American Public Health Association reported >3.2 million students in the United States are bullied each year; 160 000 students skip school every day for fear of bullying. Little is known about whether bullying affects health-related quality of life (HRQOL) among college students.

Different types of bullying experiences affected different domains of HRQOL. Precollege bullying had long-term effects on HRQOL. Verbal/relational bullying-victimization experiences, mediated via depression, affected psychological HRQOL. Findings inform preventive and clinical practice to ameliorate the impact of bullying. (Read the full article)

Conventional invasive pneumococcal disease (IPD) definition using laboratory confirmation lacks sensitivity. Using a vaccine-probe design, the FinIP trial showed that IPD disease burden and vaccine-preventable disease incidence were fourfold higher when a more sensitive outcome, clinically suspected IPD, was used.

Vaccine-preventable disease incidence (ie, absolute reduction due to PCV10 vaccination) during routine vaccination program was threefold with the more sensitive outcome of clinically suspected IPD compared with the conventional IPD definition. This has major implications for cost-effectiveness of PCVs. (Read the full article)

Increasing percentages of youth are living with chronic medical conditions. Although adolescents face peak risks for onset and intensification of alcohol and marijuana use, we know little about these behaviors and their associations with treatment adherence among chronically ill youth.

This study quantifies alcohol and marijuana use behaviors among a heterogeneous sample of chronically ill youth in aggregate and by condition, and measures associations between alcohol use/binge drinking and knowledge about alcohol interactions with medications/laboratory tests and also treatment nonadherence. (Read the full article)

Valve's tweet describes the upcoming title Half-Life: Alyx as the company's 'flagship VR game.' So you'll probably need a virtual headset to play it. The company will reveal more details on Thursday.

A panel of experts—including a national teacher's union president and an official from the Department of Education—discussed how to make teaching a more attractive profession.

Government went to war against Covid-19 with very low supplies in citizen trust and financial reserves, says Solly Moeng.

Background: This study summarizes drug resistance analyses in 4 recent phase 2b trials of the respiratory syncytial virus (RSV) fusion inhibitor presatovir in naturally infected adults.

Methods: Adult hematopoietic cell transplant (HCT) recipients, lung transplant recipients, or hospitalized patients with naturally acquired, laboratory-confirmed RSV infection were enrolled in 4 randomized, double-blind, placebo-controlled studies with study-specific presatovir dosing. Full-length RSV F sequences amplified from nasal swabs obtained at baseline and postbaseline were analyzed by population sequencing. Substitutions at RSV fusion inhibitor resistance-associated positions are reported.

Results: Genotypic analyses were performed on 233 presatovir-treated and 149 placebo-treated subjects. RSV F variant V127A was present in 8 subjects at baseline. Population sequencing detected treatment-emergent substitutions in 10/89 (11.2%) HCT recipients with upper and 6/29 (20.7%) with lower respiratory tract infection, 1/35 (2.9%) lung transplant recipients, and 1/80 (1.3%) hospitalized patients treated with presatovir; placebo-treated subjects had no emergent resistance-associated substitutions. Subjects with substitutions at resistance-associated positions had smaller decreases in viral load during treatment relative to those without, but similar clinical outcomes.

Conclusions: Subject population type and dosing regimen may have influenced RSV resistance development during presatovir treatment. Subjects with vs without genotypic resistance development had decreased virologic responses but comparable clinical outcomes.

Malaria parasites invade and replicate within red blood cells (RBCs), extensively modifying their structure and gaining access to the extracellular environment by placing the plasmodial surface anion channel (PSAC) into the RBC membrane. Expression of members of the cytoadherence linked antigen gene 3 (clag3) family is required for PSAC activity, a process that is regulated epigenetically. PSAC is a well-established route of uptake for large, hydrophilic antimalarial compounds and parasites can acquire resistance by silencing clag3 gene expression, thereby reducing drug uptake. We found that exposure to sub-IC50 concentrations of the histone methyltransferase inhibitor chaetocin caused substantial changes in both clag3 gene expression and RBC permeability, reversing acquired resistance to the antimalarial compound blasticidin S that is transported through PSAC. Chaetocin treatment also altered progression of parasites through their replicative cycle, presumably by changing their ability to modify chromatin appropriately to enable DNA replication. These results indicate that targeting histone modifiers could represent a novel tool for reversing epigenetically acquired drug resistance in P. falciparum.

Resistance to amoxicillin-clavulanate, a widely used beta-lactam/beta-lactamase inhibitor combination antibiotic, is rising globally, yet susceptibility testing remains challenging. To test whether whole-genome sequencing (WGS) could provide a more reliable assessment of susceptibility than traditional methods, we predicted resistance from WGS for 976 E. coli bloodstream infection isolates from Oxfordshire, UK, comparing against phenotypes from the BD Phoenix (calibrated against EUCAST guidelines). 339/976 (35%) isolates were amoxicillin-clavulanate resistant. Predictions based solely on beta-lactamase presence/absence performed poorly (sensitivity 23% (78/339)) but improved when genetic features associated with penicillinase hyper-production (e.g. promoter mutations, copy number estimates) were considered (sensitivity 82% (277/339); p<0.0001). Most discrepancies occurred in isolates with peri-breakpoint MICs. We investigated two potential causes; the phenotypic reference and the binary resistant/susceptible classification. We performed reference standard, replicated phenotyping in a random stratified subsample of 261/976 (27%) isolates using agar dilution, following both EUCAST and CLSI guidelines, which use different clavulanate concentrations. As well as disagreeing with each other, neither agar dilution phenotype aligned perfectly with genetic features. A random-effects model investigating associations between genetic features and MICs showed that some genetic features had small, variable and additive effects, resulting in variable resistance classification. Using model fixed-effects to predict MICs for the non-agar dilution isolates, predicted MICs were in essential agreement (±1 doubling dilution) with observed (BD Phoenix) MICs for 691/715 (97%) isolates. This suggests amoxicillin-clavulanate resistance in E. coli is quantitative, rather than qualitative, explaining the poorly reproducible binary (resistant/susceptible) phenotypes and suboptimal concordance between different phenotypic methods and with WGS-based predictions.

Carbapenem pharmacokinetic profiles are significantly changed in critically ill patients because of the drastic variability of the patients' physiological parameters. Published population PK studies have mainly focused on specific diseases and the majority of these studies had small sample sizes. The aim of this study was to develop a population PK model of imipenem in critically ill patients that estimated the influence of various clinical and biological covariates and the use of Extracorporeal Membrane Oxygenation (ECMO) and Continuous Renal Replacement Therapy (CRRT). A two-compartment population PK model with Creatinine clearance (CrCL), body weight (WT), and ECMO as fixed effects was developed using the non-linear mixed effect model (NONMEM). A Monte Carlo simulation was performed to evaluate various dosing schemes and different levels of covariates based on the pharmacokinetic/pharmacodynamic index (f%T>MIC) for the range of clinically relevant minimum inhibitory concentrations(MICs). The results showed that there may be insufficient drug use in the clinical routine drug dose regimen, and 750mg Q6h could achieve a higher treatment success rate. The blood concentrations of imipenem in ECMO patients were lower than that of non-ECMO patients, therefore dosage may need to be increased. The dosage may need adjustment for patients with CrCL ≤ 70ml/min, but dose should be lowered carefully to avoid the insufficient drug exposure. Dose adjustment is not necessary for patients within the WT ranging from 50-80 kg. Due to the large variation in PK profile of imipenem in critically ill patients, TDM should be carried out to optimize drug regimens.

Treatment of dogs naturally infected with Leishmania infantum using meglumine antimoniate (MA) encapsulated in conventional liposomes (LC) in association with allopurinol has been previously reported to promote marked reduction in the parasite burden in the main infection sites. Here, a new assay in naturally infected dogs was performed using a novel liposome formulation of MA consisting of a mixture of conventional and long-circulating (PEGylated) liposomes (LCP), with expected broader distribution among affected tissues of the mononuclear phagocyte system. Experimental groups of naturally infected dogs were as follows: LCP+Allop, receiving LCP intravenously as 2 cycles of 6 doses (6.5 mg Sb/kg/dose) at 4-day intervals, plus allopurinol at 30 mg/kg/12 h p.o. during 130 days; LC+Allop, receiving LC intravenously as 2 cycles of 6 doses (6.5 mg Sb/kg/dose), plus allopurinol during 130 days; Allop, treated with allopurinol only; non-treated control. Parasite loads were evaluated by quantitative PCR in liver, spleen and bone marrow and by immunohistochemistry in the ear skin, before, just after treatment and 4 months later. LCP+Allop and LC+Allop groups, but not the Allop group, showed significant suppression of the parasites in the liver, spleen and bone marrow 4 months after treatment, compared to the pre-treatment period or the control group. Only LCP+Allop group showed significantly lower parasite burden in the skin, in comparison to the control group. On the basis of clinical staging and parasitological evaluations, LCP formulation exhibited a more favorable therapeutic profile, when compared to LC one, being therefore promising for treatment of canine visceral leishmaniasis.

Pharmacokinetic changes are often seen in patients with severe infections. Administration by continuous infusion has been suggested to optimize antibiotic exposure and pharmacokinetic/pharmacodynamic (PK/PD) target attainment for β-lactams. In an observational study, unbound piperacillin concentrations (n=196) were assessed in 78 critically ill patients following continuous infusion of piperacillin/tazobactam (ratio 8:1). The initial dose of 8, 12 or 16 g (piperacillin component) was determined by individual creatinine clearance (CRCL). Piperacillin concentrations were compared to the EUCAST clinical breakpoint MIC for Pseudomonas aeruginosa (16 mg/L), and the following PK/PD targets were evaluated: 100% fT>1xMIC and 100% fT>4xMIC. A population pharmacokinetic model was developed using NONMEM 7.4.3 consisting of a one-compartment disposition model with linear elimination separated into non-renal and renal (linearly increasing with patient CRCL) clearances. Target attainment was predicted and visualized for all individuals based on the utilized CRCL dosing algorithm. The target of 100% fT>1xMIC was achieved for all patients based on the administered dose, but few patients achieved the target of 100% fT>4xMIC. Probability of target attainment for a simulated cohort of patients showed, that increasing the daily dose by 4 g increments (piperacillin component) did not result in substantially improved target attainment for the 100% fT>4xMIC target. To conclude, in patients with high CRCL combined with high-MIC bacterial infections, even a CI regimen with a daily dose of 24 g may be insufficient to achieve therapeutic concentrations.

As resistance to artemisinins (current frontline drugs in malaria treatment) emerges in south East Asia, there is an urgent need to identify the genetic determinants and understand the molecular mechanisms underpinning such resistance. Such insights could lead to prospective interventions to contain resistance and prevent the eventual spread to other malaria endemic regions. Artemisinin reduced susceptibility in South East Asia (SEA) has been primarily linked to mutations in P. falciparum Kelch-13, which is currently widely recognised as a molecular marker of artemisinin resistance. However, 2 mutations in a ubiquitin hydrolase, UBP-1, have been previously associated with artemisinin reduced susceptibility in a rodent model of malaria and some cases of UBP-1 mutation variants associating with artemisinin treatment failure have been reported in Africa and SEA. In this study, we have employed CRISPR-Cas9 genome editing and pre-emptive drug pressures to test these artemisinin susceptibility associated mutations in UBP-1 in P. berghei sensitive lines in vivo. Using these approaches, we have shown that the V2721F UBP-1 mutation results in reduced artemisinin susceptibility, while the V2752F mutation results in resistance to chloroquine and moderately impacts tolerance to artemisinins. Genetic reversal of the V2752F mutation restored chloroquine sensitivity in these mutant lines while simultaneous introduction of both mutations could not be achieved and appears to be lethal. Interestingly, these mutations carry a detrimental growth defect, which would possibly explain their lack of expansion in natural infection settings. Our work has provided independent experimental evidence on the role of UBP-1 in modulating parasite responses to artemisinin and chloroquine under in vivo conditions.

Treatment of exacerbations of chronic Pseudomonas aeruginosa infections in patients with cystic fibrosis (CF) is highly challenging due to hypermutability, biofilm formation and an increased risk of resistance emergence. We evaluated the impact of ciprofloxacin and meropenem as monotherapy and in combination in the dynamic in vitro CDC biofilm reactor (CBR). Two hypermutable P. aeruginosa strains, PAOmutS (MIC_{ciprofloxacin} 0.25 mg/L, MIC_meropenem 2 mg/L) and CW44 (MIC_{ciprofloxacin} 0.5 mg/L, MIC_meropenem 4 mg/L), were investigated for 120h. Concentration-time profiles achievable in epithelial lining fluid (ELF) following FDA-approved doses were simulated in the CBR. Treatments were ciprofloxacin 0.4g every 8h as 1h-infusions (80% ELF penetration), meropenem 6 g/day as continuous infusion (CI; 30% and 60% ELF penetration) and their combinations. Counts of total and less-susceptible planktonic and biofilm bacteria and MICs were determined. Antibiotic concentrations were quantified by UHPLC-PDA. For both strains, all monotherapies failed with substantial regrowth and resistance of planktonic (≥8log₁₀ CFU/mL) and biofilm (>8log₁₀ CFU/cm²) bacteria at 120h (MIC_{ciprofloxacin} up to 8 mg/L, MIC_meropenem up to 64 mg/L). Both combination treatments demonstrated synergistic bacterial killing of planktonic and biofilm bacteria of both strains from ~48h onwards and suppressed regrowth to ≤4log₁₀ CFU/mL and ≤6log₁₀ CFU/cm² at 120h. Overall, both combination treatments suppressed amplification of resistance of planktonic bacteria for both strains, and biofilm bacteria for CW44. The combination with meropenem at 60% ELF penetration also suppressed amplification of resistance of biofilm bacteria for PAOmutS. Thus, combination treatment demonstrated synergistic bacterial killing and resistance suppression against difficult-to-treat hypermutable P. aeruginosa strains.

Six sources confirmed Apple changed its mind on end-to-end encrypted backups two years ago following an FBI complaint and concerns users could lose access to their own data.

Equity markets have rallied Monday as countries eased coronavirus lockdown measures, but oil prices tumbled as a supply glut offset output cuts.

In number 10 in our countdown, I tried to offer a few thoughts to funders as they embraced new agendas and looked to avoid repeating yesterday's missteps.

BACKGROUND AND OBJECTIVES:

Rates of sexually transmitted infections (STIs) have increased over the decade. Guidelines recommend HIV testing with incident STIs. Prevalence and factors associated with HIV testing in acute STIs are unknown in adolescents. Our objective was to determine the prevalence of completed HIV testing among adolescents with incident STIs and identify patient and health care factors associated with HIV testing.

Jake Griggs, who will graduate Saturday with a 3.95 GPA with dual majors in management and political science, has been named Smeal’s spring 2020 management and organization student marshal.

To assess public perceptions about COVID-19 and identify populations whose behaviors put them at risk of infection, researchers at Penn State have released an online survey for the general public.

Free apps are cool, but a few bucks can get you so much more. If you are looking to buy in the Google Play store, here are the best paid Android apps to put on your phone.

I was just sitting down to write this week's column when the Red Arrows flew right over my head.

The world's largest education research group said it will work to convert much of the annual meeting into a virtual experience for attendees and presenters.

Katherine H. Burns
Oct 1, 2010; 126:638-646
ARTICLES

Yong Y. Han
Dec 1, 2005; 116:1506-1512
ARTICLES

Do your bit for the environment and reduce clutter in your own home or office by cutting down on the paper you use and keep. Learn how to go paperless with productivity expert Jill Duffy's tips and suggestions.

In a shocking display of ignorance, pay for performance has become reformers' blitzkrieg. Both common sense and research are being ignored.

The champion of disruptive innovation in business and education passed away this month. One of Christensen's co-authors of "Disrupting Class," Michael B. Horn, assesses the impact his late colleague had on schools.

A new study finds that materials often portray scientists as geniuses working alone—a framing that can make students think science isn't for them.

Juan Roberto Meléndez-Colón was exonerated, in 2002, after nearly 18 years on death row for a crime he did not commit. He visited Penn State Fayette, The Eberly Campus to share his story on March 5.

Two-factor authentication, or 2FA, is becoming increasingly common, but one reader points out that it seems easy to get around its protection. Is he right? Security expert Max Eddy takes a look.

The spring season at Penn State College of Medicine is packed full of research presentations, awards and ceremonies. Since experts cannot predict when social distancing guidelines will be relaxed, College of Medicine leaders plan on celebrating many of these springtime celebrations virtually — including commencement.

Student Wellness Project offers help and support to Penn State York students during time away from campus, and remote learning.

Holyrood’s Economy, Energy and Fair Work Committee is to have an inquiry into the role of Scottish Development International (SDI) in developing a Scotland that competes on the international stage.

OMer Martin sees Muslims coming to Christ as he ministers to Turkish speakers in France.

The bill would mandate local bullying policies and require data collection and reporting at the local, state, and federal level.

The forthcoming bullying debate will prompt the first votes on lesbian, gay, bisexual, and transgender issues since the U.S. Supreme Court ruling on the right to same-sex marriage.

By Sr. Joan L. Roccasalvo, C.S.J.

He’s been dubbed: “The Poet-Philosopher of Baseball,” “A Voice for the Ages,” “The Velvet Voice.” He’s been compared to Walter Cronkite, Mark Twain, and Garrison Keilor.  

In 1982, the Hollywood Walk of Fame honored him with a star among the Greats of stardom in the same year the National Baseball Hall of Fame enshrined his name among the Greats of baseball.

Vin Scully may be the very model of sartorial perfection, but it’s not the wardrobe that has endeared him to baseball for sixty-seven years. It’s his deep baritone voice and the power of his words.

A Catholic Education

There’s much to be said for childhood dreams.  At eight, when he wrote an assignment about his future, Vin imagined himself as a sports commentator. That dream has come true.

Vin Scully was born in the Bronx, N.Y. and received his elementary school education from the Sisters of Charity.  At Fordham Prep and Fordham University, both conducted by the Jesuits, his eager mind opened itself wide to the liberal arts, to Latin and Greek, science, literary and refining arts. He acted in plays, engaged in debate, learned to read and write well, and above all, to speak well; this is eloquentia perfecta, the hallmark of Jesuit education. When his head was not in books, he took up menial jobs to make ends meet delivering beer, pushing garment racks, and cleaning silver in the basement of the Pennsylvania Hotel in New York City. Vin Scully, the Renaissance man graduated from Fordham in 1949 with a major in communications.

With the Brooklyn Dodgers

In 1947, baseball executive Branch Rickey signed Jackie Robinson to play infield on the Brooklyn Dodgers team.  Against a tide of opposition, Rickey was determined to integrate the ball club.  Against a tide of opposition, the all-round athlete broke the color barrier in major league baseball at a great personal cost to him and his wife Rachel.  If you wanted to see electricity personified, you went to Ebbets Field where you could fix your eyes on Jackie at home plate and on the base pads tantalizing the opposing team.  There was nothing like it.  Said Rickey, “There was never a man in the game who could put mind and muscle together quicker than Jackie Robinson.”

Three years later, a twenty-two year old Vin Scully joined veteran Dodgers announcers, Red Barber and Connie Desmond to complete the broadcasting team.  As the rookie, Scully was assigned to announce only two innings.  Before long, he was announcing World Series games. He was not yet thirty.

Scully called Jackie Robinson “perhaps the most exciting, most driven player I’ve ever seen.” He spoke fondly of two other players:  “Gil Hodges was probably my all-time favorite.  He was as straight an arrow as they come.”  Duke Snider was “a true star. Subject to teasing from teammates. Great talent.”

When, in 1955, the Brooklyn ‘Bums’ won their only World Series, Scully stood and proclaimed: “Ladies and Gentlemen, the Brooklyn Dodgers are the champions of the world.”

Heartbreak in Brooklyn

In 1957, the Dodgers relocated from Brooklyn to Los Angeles.  For years, Walter O’Malley, the team’s major co-owner, had been searching for a more suitable land on which to build a new ballpark. When he and Robert Moses, the controversial construction coordinator of New York City, could not agree on a real estate price for a new Brooklyn location, O’Malley lost no time in accepting the offer of Los Angeles officials to purchase land suitable for building the ballpark he had wanted to build in Brooklyn.  Their departure triggered a virtual depression in Brooklyn.  The fans lost not only their team but also their beloved announcer.  Scully had pledged his loyalty to the team and followed them to Los Angeles.  

When, in 1959, the Los Angeles Dodgers honored Roy Campanella, one of the stars on the Brooklyn team, he was wheeled onto the field for a ceremony of lighting candles in his honor.  (He had been injured in a car accident leaving him paralyzed.) Vin Scully stood, and in tribute, spoke these memorable words:

“The lights are now starting to come out, like thousands and thousands of fireflies, starting deep in center field, glittering to left, and slowly, the entire ballpark. A sea of lights at the Coliseum. Let there be a prayer for every light, and wherever you are, maybe you, in silent tribute to Roy Campanella, can also say a prayer for his well-being. Campanella, for thousands of times, made the trip to the mound to help somebody out: a tired pitcher, a disgusted youngster, a boy perhaps who had his heart broken in the game of baseball. And tonight, on his last trip to the mound, the city of Los Angeles says hello.”

Honorary Doctorate from Alma Mater

In May, 2000, Vin Scully received an Honorary Doctorate of Humane Letters from Fordham University. In his address to the graduates, he shared some memories of his years at Fordham.  . . . “I was once you.  I walked the halls you walked.  I sat in the same classrooms.  I took the same notes and sweated out the final exams.  I played sports on your grassy fields. I hit a home run here—in Jack Coffey Field against CCNY—the only one I ever hit.”

Fordham, he said, evoked three words for him: home, love and hope. Home, because he spent eight years at Fordham both in the preparatory school and as an undergraduate. Love, because he made lifelong friends, and hope because Fordham is where his dreams thrived.

He urged all present “to take some time away from the craziness around you to foster the things that are important. Don’t let the winds blow away your dreams or your faith in God. And remember, sometimes your wildest dreams come true.”

In presenting the award, Michael T. Gillan, dean of Fordham College of Liberal Studies, noted that “when Jesuit schoolmasters developed their plan of studies in the 16th and 17th centuries, they defined “the goal of Jesuit education as eloquentia perfecta … which connotes a mastery of expression that is informed by good judgment and consistent principles. Those Jesuit schoolmasters of another age, if they had known anything about baseball, would certainly have approved the rhetorical gifts of the man who has been the voice of the Dodgers for the past fifty-one years, Vincent E. Scully.”

The Scully Anaphora

For years, every Scully broadcast has repeated the same avuncular opening:  “It’s time for Dodger baseball! Hi, everybody, and a very pleasant afternoon/evening to you, wherever you may be. Pull up a chair and relax;” The poet-philosopher announced the games painting vivid word pictures with his musical voice, tinged with Irish inflection.

Scully held himself to three rules:  Avoid criticizing managers and umpires; keep your personal opinions to yourself; avoid using clichés to describe a play. The Scully trademark, he insists, is silence—silence to allow the roar of the crowd to touch the listening audience.

Scully in His Own Words     

There are numerous quotes attributed to Mr. Scully. In describing Tom Glavine as a strike-out pitcher, he mused: “He’s like a tailor, a little off here, a little off there, and you’re done, take a seat.” The talent of Stan Musial of the St. Louis Cardinals amazed Scully:  “How good was Stan Musial? He was good enough to take your breath away.”

Vin was known to spin some philosophy out of the play at the moment.  In 1991, he remarked: “Andre Dawson has a bruised knee and is listed as day-to-day (Pause).  Aren’t we all?”  

Then there were his philosophical quips: “Good is not good enough when better is expected.” “Statistics are used much like a drunk who uses a lamp post—for support, not illumination.” “Losing feels worse than winning feels good.”     

One day, when Vin joked that Joe Torre might be apprehensive about returning from third base to catcher after getting hit by a foul tip.  “If he were apprehensive, Torre would forever be known as “Chicken Catcher Torre.”  At this, the crowd groaned.

Awards

Listed among Vin Scully’s many awards are:
1976 Most Memorable Personality in L.A. Dodger history by Dodger fans
1982 Induction into the National Baseball Hall of Fame as the Ford C. Frick Award recipient.
Four times, voted as the country’s Outstanding Sportscaster.  
Twenty-two times voted, as California Sportscaster of the Year by the National Sportscasters and Sportswriters Association.
2009  NAB Broadcasting Hall of Fame
2009  Ambassador Award of Excellence by the LA Sports & Entertainment Commission
2014 The Gabriel Personal Achievement Award from the Catholic Academy of Communication Professionals.

Personal Life

Vin Scully has not been one to wear his feelings in the open.  Yet, he has experienced two family tragedies.  In 1972, after fifteen years of married life, his wife died from an accidental medical overdose.  The next year, his thirty-three old son Michael was killed in a helicopter crash while working for the ARCO Transportation Company.  A chemist, he was inspecting oil pipelines for leaks near Fort Tejon.

Vin credits his strong Roman  Catholic  faith for helping him cope with family grief and then to resume his work as an announcer. “As long as you live,” he reflects, “keep smiling because it brightens everybody’s day.”

The Final Inning

The longevity of Vin Scully’s baseball life has drawn to a conclusion.  As part of a conference call before the Dodgers played the Giants on Sept 19th, Scully he spoke about all the attention he had received in the closing days of his long career: “First of all, I attribute it to one thing and one thing only,” Scully reflected, “God’s Grace to allow me to do what I’ve been doing for 67 years. To me, that’s really the story. Not really me, I’m just a vessel that was passed hand-to-hand, down through all those years. So I don’t take it to heart as some great compliment. I just realize that because I’ve been doing this for 67 years, that’s why everybody wants to talk about it. So I think I’ve kept it in proper perspective” (Courtesy of MLB Network).

Finally, a favorite Irish prayer and blessing from Mr. Scully:

May God give you for every storm, a rainbow,
For every tear, a smile,
For every care, a promise,
And a blessing in each trial.
For every problem life send,]
A faithful friend to share,
For every sigh, a sweet song
And an answer for each prayer.

Dear Mr. Scully, ad multos annos.

 

The Leonardo opened its doors on Tuesday 3 March. Developers of the 234-metre tall building said the 240-suite hotel and residences were ready for occupation and some residents were already in the process of moving in.

On March 21, more than 120 student government representatives from 19 Penn State campuses virtually attended the Council of Commonwealth Student Governments’ first sustainability summit, featuring a poster expo of students showcasing their campus’ sustainability efforts, and a presentation on students’ potential impact on climate change by Richard Alley, Evan Pugh Professor of Geosciences.

Graduating members of Penn State Scranton’s Lambda Pi Eta Alpha Epsilon Pi chapter received their honor cords recently during a virtual celebration. Lambda Pi Eta is the official honor society of the National Communication Association and currently, the only academic honor society at Penn State Scranton.

The deal will combine the CBS television network, CBS News, Showtime cable networks with MTV Networks, Nickelodeon, Comedy Central and Paramount Pictures.

In India, however, this is not likely to be a separate offering — Disney titles are being made available on the homegrown Hotstar, with no change in subscription plans, as of now.

<strong>New Delhi:</strong> Gauri Khan took a stroll down her memory lane and shared a throwback family picture from their vacation featuring husband and megastar Shah Rukh Khan and their two kids. However, it is the doting father and a husband's response over the adorable picture which will just melt

Salman Khan's Radhe is still in the post-production stage

With the passing of Reverend Billy Graham on Wednesday, February 21 2018, President Trump has ordered American flags at all government buildings and facilities be flown at half-staff the day of his interment, this Friday March 2. In concurrence with the President’s order, Governor Carney has ordered the American and Delaware flags at state buildings […]

More than 30 Delaware farmers have Christmas trees available for First State merrymakers this holiday season, with firs, spruces and pines in abundance – and easy to find and buy with the Delaware Fresh mobile app. The app and a related website, de.gov/christmastrees, feature locations, hours and other shopping information.

More than 30 Delaware farmers have Christmas trees available for First State families this holiday season, with local firs, spruces and pines in abundance – and easy to find and buy with the Delaware Fresh mobile app and the Delaware Buy Local guide, de.gov/buylocal.