the

The iceberg illusion




the

Expanding the repertoire of ion traps

Researchers are simultaneously shrinking mass specs and broadening their tandem capabilities




the

Detecting traces of fentanyl in the field

Mini mass spec can detect lower opioid levels than other methods




the

Meet the Janelia chemist crafting glowing molecular tools for neuroscientists

Luke Lavis’s lab teaches old dyes new tricks at the HHMI campus




the

Discovery of new poppy enzyme might help improve yeast-based opiate synthesis

Adding enzyme to engineered yeast boosts production of thebaine, a key morphine intermediate




the

Deployment of Merck’s experimental Ebola vaccine well under way in the Democratic Republic of Congo

The first goal is to thwart the outbreak, but researchers also hope for new insights into combating the virus




the

Experimental cancer cell therapies have nearly doubled in six months

A new report from the Cancer Research Institute highlights the U.S. and China as cell therapy leaders




the

The difficult search for the right recipe in cancer immunotherapy

With so many ingredients on hand, can the oncology community figure out how to sensibly and efficiently combine checkpoint inhibitors with other drugs?




the

Drug service provider Alcami to go to another private equity firm

New investor takes on a company trying to combine a range of pharmaceutical services




the

The ACS Board of Directors demystified




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The mega-agency




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U.S. EPA advisers want to give formal feedback on plan to restrict the science used by agency

Surprised by proposal, scientific experts to ask agency chief to wait for their feedback before finalizing rule




the

Giving enzymes floppy surfaces can enhance their activity

Added surface glycine residues cause partial unfolding that adapts enyzyme to low temperatures




the

To shrink electronics further, innovative chemical deposition methods may save the day

Researchers experiment with area-selective atomic layer deposition to precisely place layers of conducting and insulating materials within circuits




the

Shining the light on outstanding contributions by women chemists




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Spectroscopy method measures enantiomeric excess on the fly

Combining vibrational circular dichroism and infrared spectroscopy yields real-time probe of asymmetric catalytic reactions




the

Drug service provider Alcami to go to another private equity firm

New investor takes on a company trying to combine a range of pharmaceutical services




the

U.S. EPA advisers want to give formal feedback on plan to restrict the science used by agency

Surprised by proposal, scientific experts to ask agency chief to wait for their feedback before finalizing rule




the

BridgeBio launches CoA Therapeutics to treat a rare neurodegenerative disease

The startup is developing allosteric activators to increase levels of the vital metabolic molecule coenzyme A in pantothenate kinase-associated neurodegeneration




the

Periodic Graphics: The chemistry of slime

Chemical educator and Compound Interest blogger Andy Brunning wrings all the molecular details out of the popular goo




the

Plastics recycling with microbes and worms is further away than people think

Headlines about plastic-eating organisms belie tough, competitive road to development




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ACS Board actions from the June executive meeting




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Alexion partners with Complement Pharma on neurodegenerative therapy




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Polarized light and the magic angle: Scientists making art




the

Chemists synthesize Saturn-shaped molecule

Flat, macrocyclic host captures fullerene guest with CH–π interactions




the

Setup may make transferring <em>tert</em>-butyl lithium and other pyrophoric reagents safer

Simple pieces of equipment decrease the danger of moving small volumes of chemicals prone to igniting




the

Synthetic biology could enable bioweapons development

A new National Academies report names and classifies the kinds of biological weapons that could emerge from techniques like CRISPR gene editing and DNA synthesis




the

A quest to drug the undruggable

Listen to the latest Stereo Chemistry episode that explores why certain drug targets are so vexing, and the cutting edge approaches chemists are taking to finally crack them




the

Enzyme conjugate synthesizes DNA

Method is possible replacement for phosphoramidite-based DNA synthesis




the

Sarepta’s Duchenne gene therapy shows promise in small study

The early peek at data from a Phase I/II study excited families, physicians, and investors 




the

Novacap to enter the U.S. by acquiring PCI Synthesis

French pharmaceutical services firm is latest to move into the U.S.




the

2-step synthesis yields large 2-D COF crystals

Separating crystal nucleation and growth processes is key to controlling crystal dimensions




the

Expanding the glucose meter’s repertoire

Molecular logic gates allow personal glucose meters to respond to many other targets




the

How the Women Chemists Committee stays relevant after 90 years




the

Topological materials move from the world of theoretical physics to experimental chemistry

These exotic materials could find applications in electronics, catalysis, and quantum computing




the

Setup may make transferring <i>tert</i>-butyl lithium and other pyrophoric reagents safer

Simple pieces of equipment decrease the danger of moving small volumes of chemicals prone to igniting




the

Gene therapy start-up Freeline Therapeutics raises $116 million




the

BridgeBio licenses compounds from NeuroVive and launches Fortify Therapeutics




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Adventures with the periodic table




the

Out of the sea and into the factory for Acasti’s heart drug ingredient

Acasti picks CordenPharma to extract omega-3s from krill




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Theracos becomes increasingly reliant on contract manufacturing as its drug advances

Piramal sites on different continents have become involved in producing Theracos’s diabetes treatment




the

AbbVie invests in switchable CAR-T therapies for cancer

The drug company is partnering with Calibr to develop universal CAR T-cells directed to different tumors via antibody switches




the

Celgene partners with Skyhawk Therapeutics to drug RNA with small molecules

Skyhawk will receive $60 million up front to develop drug candidates that target RNA in neurological diseases




the

Acknowledging the spies on campus

As universities embrace rapid communications and international students, they are learning that the free exchange of ideas comes with risks




the

Magnets tune the friction of a designed surface

Multifunctional surfaces could control liquid and particle movement in microfluidics or pipes




the

Exploring the claims of an electric bandage

The electroactive material’s makers say it can kill antibiotic-resistant bacteria and battle body odor




the

Untangling the CRISPR cancer scare

News reports linking the gene-editing technology to cancer are the latest in a series of hyped alarms due to be tested in humans soon




the

Chemists Celebrate Earth Week spreads awareness about the environment

On its 15th anniversary, ACS outreach program expands to a weeklong celebration




the

AbbVie invests in switchable CAR-T therapies for cancer

The drug company is partnering with Calibr to develop universal CAR T cells directed to different tumors via antibody switches




the

Pot purveyors get wise to instrumentation; steelhead trout shift their genetic gears