the

“Sergeants-and-soldiers” principle in the synthesis of intrinsically chiral Au13 clusters

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR03810J, Paper
Open Access
Katsuya Mutoh, Sonomi Kawakita, Teppei Yahagi, Takuya Nakashima
Single chiral ligand coordination effectively deracemizes intrinsically chiral Au13 clusters with binary mixed ligands of chiral and achiral diphosphines.
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Correction: Ce6-Conjugated and polydopamine-coated gold nanostars with enhanced photoacoustic imaging and photothermal/photodynamic therapy to inhibit lung metastasis of breast cancer

Nanoscale, 2024, 16,20354-20355
DOI: 10.1039/D4NR90194K, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Ziwei Li, Fan Yang, Di Wu, Yanhong Liu, Yang Gao, Haichen Lian, Hongxin Zhang, Zhibin Yin, Aiguo Wu, Leyong Zeng
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the

Glycosylated AIE-active Fe (III) photosensitizer activated by tumor microenvironment for synergistic type I photodynamic and chemodynamic therapy

Nanoscale, 2024, Accepted Manuscript
DOI: 10.1039/D4NR03871A, Paper
Gai-li Feng, Wei Zhou, Jinping Qiao, Guang-Jian Liu, Guo-Wen Xing
Photodynamic therapy (PDT) and chemodynamic therapy (CDT) are both promising cancer treatments to inhibit tumor cells by generating highly cytotoxic reactive oxygen species (ROS). Herein, we report a novel tumor...
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the

Advances in Flexible Ionic Thermal Sensors: Present and Perspectives

Nanoscale, 2024, Accepted Manuscript
DOI: 10.1039/D4NR03423F, Review Article
Zehao Zhao, Yun Shen, Run Hu, Dongyan Xu
Ionic thermal sensors (ITSs) represent a promising frontier in sensing technology, offering unique advantages over conventional electronic sensors. Comprising a polymer matrix and electrolyte, these sensors possess inherent flexibility, stretchability,...
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the

Applications of nanotheranostics in the second near-infrared window in bioimaging and cancer treatment

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR03058C, Review Article
Huimin Li, Pengju Li, Jiarui Zhang, Ziyi Lin, Lintao Bai, Heyun Shen
This review summarized the application of the second near-infrared nano-platform in the field of nano-agents design, optical imaging and cancer treatment, aiming at providing profound insights into its development status and future challenges.
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the

Minimizing defect states through multidentate coordination and morphology regulation for enhancing the performance of inverted perovskite solar cells

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR03140G, Paper
Himangshu Baishya, Mayur Jagdishbhai Patel, Ramkrishna Das Adhikari, Deepak Yadav, Parameswar Krishnan Iyer
The interaction between CO and Pb2+ regulated grain growth, enhanced crystallinity that effectively passivated non-radiative recombination centres and CF3 group stabilizes the perovskite structure by interacting with FA and Pb cationic defects.
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the

Oxygen electrode catalysis in N-doped graphene: the role of nitrogen coordination and solvation effects

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR03645J, Paper
Junxian Liu, Yun Wang, Yuantong Gu, Liangzhi Kou
The significance of explicit solvents in describing the adsorption behaviors of ORR/OER intermediates is emphasized. A higher HOMO level of active sites enhances binding to oxygen intermediates, thereby improving ORR/OER activity.
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the

Investigation of the temperature effect on the formation of a two-dimensional self-assembled network at the liquid/solid interface

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR02600D, Paper
Open Access
Tamara Rinkovec, Eveline Croket, Hai Cao, Jeremy N. Harvey, Steven De Feyter
In this work, we investigate the temperature effect on the formation of self-assembled molecular networks (SAMNs) at the liquid/solid interface, focusing on an alkylated achiral glycine derivative at the 1-phenyloctane/HOPG interface.
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the

Macroscopic chiral symmetry breaking in gelation of Fmoc-amino acids: homochiral selective secondary nucleation promoted by the choice of solvent or stirring

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR04011B, Communication
Kentaro Tashiro
Homochiral selective secondary nucleation, promoted by the choice of solvent or stirring, was suggested as the key process for the emergence of macroscopic chiral symmetry breaking in the gelation of Fmoc amino acids.
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the

Facile synthesis of defective ZnS-ZnO composite nanosheets for efficient piezocatalytic H2 production

Nanoscale, 2024, Accepted Manuscript
DOI: 10.1039/D4NR03733B, Paper
Xiaoxiao Lu, Xiaojing Zhao, Xiangyu Chen, Miaoqiong Xu, Miaoling Huang, Wen-Jie Chen, Yubin Liu, Xiaoyang Pan
A facile approach was developed for the synthesis of ultrathin ZnS-ZnO nanosheets. By simply manipulating the synthetic temperature, ZnS-ZnO composite nanosheets with sulfur vacancy are successfully obtained using ZnS(en)0.5 as...
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the

Ab-initio Calculations of Vibrational Fingerprints in the Photoluminescence of Graphene Quantum Dots

Nanoscale, 2024, Accepted Manuscript
DOI: 10.1039/D4NR02458C, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Ruoyu Wu, Peng Han, Tobias Dittmann, Fu-He Wang, Yan Zhang, Gabriel Bester
We use a computational method based on ab initio (constrained) density functional theory to obtain the photoluminescence spectrum of graphene quantum dots with up to 240 carbon atoms, including the...
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the

Enhanced antifungal activity of siRNA-loaded anionic liposomes against the human pathogenic fungus Aspergillus fumigatus

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR03225J, Communication
Open Access
Yidong Yu, Theresa Vogel, Sina Hirsch, Jürgen Groll, Krystyna Albrecht, Andreas Beilhack
Application of anionic liposomes co-loaded with amphotericin B and siRNA demonstrates a temporary antifungal effect lasting 3–4 days, highlighting their therapeutic potential.
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the

Insights into the electrochemical catalytic mechanism of atomically dispersed metal on h-BCN monolayer

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR02845G, Paper
Na Zhou, Yanning Wang, Jiao Wang, Panchao Zhao, Hang Zhang
Exploiting efficient and inexpensive electrocatalysts for the oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) is of great significance for the rapid development of renewable energy technologies.
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the

DON encapsulated carbon dot–vesicle conjugate in therapeutic intervention of lung adenocarcinoma by dual targeting of CD44 and SLC1A5

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR00426D, Paper
Afreen Zaman, Aparajita Ghosh, Anup Kumar Ghosh, Prasanta Kumar Das
HACD–TMAV, a carbon dot–vesicle conjugate, selectively delivered glutamine inhibitor DON to CD44-enriched cancer cells, inducing ROS triggered apoptosis by dual targeting CD44 and SLC1A5 through downregulation of PI3K/AKT/mTOR signalling cascade.
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the

Photoemission spectroscopy and microscopy for Ta@Si16 superatoms and their assembled layers

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR02778G, Paper
Open Access
Masahiro Shibuta, Tsutomu Ohta, Toshiaki Kamoshida, Kana Yamagiwa, Hironori Tsunoyama, Tomoya Inoue, Tsugunosuke Masubuchi, Atsushi Nakajima
An alkaline-like Ta-encapsulating Si16 superatom film was fabricated on a C60 substrate. Charge transfer between Ta@Si16 and C60 lowers the work function. In the multilayer film, the central Ta atom's positive charge is compensated by the Si16 cage.
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the

Design of a new process for the stabilization of FeS–Bi2S3 hybrid nanostructure and its application as a field emitter

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR04138K, Paper
Arushi Arora, Anima Mahajan, Nausad Khan, Santanu Ghosh, Menaka Jha
Design of a new process for the fabrication of FeS–Bi2S3 anisotropic nanostructure for field emission application.
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the

The interaction of glycogen nanoparticles with human blood

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR03034F, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Nadiia Davydiuk, Vaidehi Londhe, Manfred F. Maitz, Carsten Werner, Andreas Fery, Quinn A. Besford
Glycogen nanoparticles are emerging biomaterials for theranostic applications. This study investigates the interactions of glycogen nanoparticles from different sources with human blood, finding that all are hemocompatible nanomaterials.
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the

Preceramic polymer hybridized phenolic aerogels and the derived ZrC/SiC/C ceramic aerogels with ultrafine nanocrystallines

Nanoscale, 2024, Accepted Manuscript
DOI: 10.1039/D4NR03470H, Paper
Ding Nie, Hangyu Zhong, Hongli Hu, Zhenhua Luo, Boxing Zhang
Phenolic and carbon aerogels have important applications for thermal insulation and ablative resistance materials in aerospace areas. However, their antioxidant ability in long-term and high-temperature aerobic environments is facing serious...
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the

pH controlled synthesis of end to end linked Au nanorod dimer in an aqueous solution for plasmon enhanced spectroscopic applications

Nanoscale, 2024, Accepted Manuscript
DOI: 10.1039/D4NR03235G, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Satyajit Patra, Shubhangi Sharma, Théo Minchella, Susmita Pradhan, Davy Gerard, Quanbo Jiang
End-to-end linked nanorod dimer nanogap antennas exhibit superior plasmonic enhancement compared to monomers due to the coupling of localized surface plasmon resonances (LSPR) of individual nanorods. However, controlling the assembly...
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the

Nanoparticle’s shape is the game-changer for blood-brain barrier crossing and delivering through tunneling nanotubes among glioblastoma cells.

Nanoscale, 2024, Accepted Manuscript
DOI: 10.1039/D4NR03174A, Paper
Open Access
Giulia Sierri, Ines Saenz-de-Santa-Maria, Antonio Renda, Marcus Koch, Patrizia Sommi, Umberto Anselmi-Tamburini, Mario Mauri, Alessia D'Aloia, Michela Ceriani, Domenico Salerno, FRANCESCO MANTEGAZZA, Chiara Zurzolo, Francesca Re
Tunneling Nanotubes (TNTs) are thin, dynamic, long membrane protrusions that allow the intercellular exchanges of signal clues, molecules and organelles. The presence of TNTs and their involvement as drug delivery...
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the

Synthesis, Characterization, Genotoxicity Assessment and Antibacterial Applications of Zanthoxylum armatum Silver Nanoparticles (ZASNP) with Antibiotic Efficacy Enhancement Potential

Nanoscale, 2024, Accepted Manuscript
DOI: 10.1039/D4NR03608E, Paper
Open Access
Nikita Quadri, Manjunath M. Setty, Anshumali Awasthi, Usha Yogendra Nayak, Minakshi Singh, Sharad Sharma
The study aimed to develop alternative antibacterial treatments by combining traditional herbal knowledge with modern nanotechnology. This approach targets multiple bacterial strains, combats antibiotic resistance, and offers solutions for treating...
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the

Impact of catalyst support on water-assisted CO oxidation over PdO/MO2 (M = Sn, Ti, and Si) catalysts: experimental and theoretical investigation

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR03963G, Paper
Kun Liu, Luliang Liao, Guangfu Liao
This study investigates the influence of different supports on PdO-based catalysts during CO oxidation, particularly under humid conditions.
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the

A liposome-based assay for cancer biomarker detection: exploring the correlation between platelet-derived microvesicles and NSCLC-associated miRNAs

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR03704A, Paper
Mohamed Aimene Benariba, Kanza Hannachi, Sha Zhu, Yuting Zhang, Xiaoli Wang, Nandi Zhou
This research reveals a significant correlation between PMVs and their associated miRNA. Additionally, the liposome-based assay demonstrates enhanced sensitivity with calcium-induced platelet activation.
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the

Unraveling the Ammonia Sensing Behavior and Degradation Pathways of Novel Lead-Free MA2CuBr4 based Ammonia Sensor

Nanoscale, 2024, Accepted Manuscript
DOI: 10.1039/D4NR02943G, Communication
Abinash Tiwari, Arjumand Mir, Aswani Yella
We report a lead-free copper-based halide perovskite gas sensor to detect ammonia gas at ambient temperature. The sensor uses methylammonium copper bromide as the active material and can trace ammonia...
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the

Exploring Graphene's Impact on Graphite/PANI Matrix Composites: High-Press Fabrication and Enhanced Thermal-Electrical Properties

Nanoscale, 2024, Accepted Manuscript
DOI: 10.1039/D4NR03171G, Paper
Murat OZLEK, Merve Sehnaz Akbulut, Engin Burgaz
This study investigates the effects of graphene content and applied press on electrical and thermal conductivities of graphite/polyaniline (GP) and graphite/graphene/polyaniline (GGP) composites which were produced by using direct mixing...
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the

Shape-controlled, water-assisted synthesis of 2D luminescent CsPb2Br5 perovskite microcrystals for highly responsive UV detectors

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR03021D, Paper
Dipayan Ray, Ankush Saini, Ankit Kumar, Sumit Kumar, Monojit Bag, Prasenjit Kar
Water-assisted, growth-controlled synthesis of CsPb2Br5 microcrystals for fast responsive UV-detectors.
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the

Factors influencing the chiral imprinting in perovskite nanoparticles

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR03329A, Minireview
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Nazifa Tabassum, Brian P. Bloom, Gouranga H. Debnath, David H. Waldeck
This work discusses the imprinting of optoelectronic chirality on hybrid-organic inorganic perovskites, which are a new class of chiral nanomaterials for manipulation and control of spin polarized current and circularly polarized light.
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the

Effect of number ratio and size ratio on the formation of binary superlattices assembled by two-sized polymer-tethered spherical nanoparticles

Nanoscale, 2024, Accepted Manuscript
DOI: 10.1039/D4NR04032E, Communication
Open Access
Jinlan Li, Xin Yu, Jianing Zhang, Jing Jin, Yanxiong Pan, Xiangling Ji, Wei Jiang
Binary superlattices (BNSLs) with unique configurations are of great interest, attributing to the interaction between two kinds of nanoparticles, providing potential applications in sensing, electronic and optical fields. Here, polystyrene...
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the

Quantifying the polar skyrmion motion barrier in an oxide heterostructure

Nanoscale, 2024, Accepted Manuscript
DOI: 10.1039/D4NR03686G, Paper
Lizhe Hu, Yuhui Huang, Yong Jun Wu, Zijian Hong
Exotic polar topologies such as polar skyrmions have been widely observed in the ferroelectric superlattice system. The dynamic motion of the polar skyrmion under external forces holds promise for applications...
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the

Aptamer-functionalized Nucleic Acid Nanotechnology for Biosensing, Bioimaging and Cancer Therapy

Nanoscale, 2024, Accepted Manuscript
DOI: 10.1039/D4NR04360J, Review Article
Xiaofang Zheng, Zhiyong Huang, Qiang Zhang, Guoli Li, Minghui Song, Ruizi Peng
Nucleic acids have enabled to fabricate self-assemblies and perform dynamic operations. Among different functional nucleic acids, aptamers can specifically bind to wide range of targets including proteins, viral antigens, living...
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the

Electrical transport phenomena in two-dimensional metallic 2H-NbSe2: an experimental and theoretical study

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR03369H, Paper
Jeongmin Kim, Seonhye Youn, Damin Lee, Chan Woong Kim, Hongjae Moon, Seok-Hwan Chung, Hoyoung Kim, Dong Hwan Kim, Sumin Kim, Jong Wook Roh, Joonho Bang, Wooyoung Lee
Two-dimensional (2D) metallic transition metal dichalcogenides (TMDCs) have attracted extensive interest in various fields owing to their unique electronic properties.
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the

Theoretical Understanding of the In-plane Tensile Strain Effects on Enhancing the Ferroelectric Performance of Hf0.5Zr0.5O2 and ZrO2 Thin Films

Nanoscale, 2024, Accepted Manuscript
DOI: 10.1039/D4NR03333G, Paper
Kun Hee Ye, Taeyoung Jeong, Seungjae Yoon, Dohyun Kim, Cheol Seong Hwang, Jung-Hae Choi
The in-plane tensile strain was reported to enhance the ferroelectricity of Hf1-xZrxO2 thin films by promoting the formation of the polar orthorhombic (PO-) phase. However, its origin remains yet to...
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the

Hydrodynamic Slip in Nanoconfined Flows: A Review of Experimental, Computational, and Theoretical Progress

Nanoscale, 2024, Accepted Manuscript
DOI: 10.1039/D4NR03697B, Review Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Abdul Aziz Shuvo, Luis E. Paniagua-Guerra, Juseok Choi, Seong H. Kim, Bladimir Ramos Alvarado
Nanofluidics has made significant impacts and advancements in various fields, including ultrafiltration, water desalination, biomedical applications, and energy conversion. These advancements are driven by the distinct behavior of fluids at...
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the

Ultra-efficient delivery of CRISPR/Cas9 using ionic liquid conjugated polymers for genome editing-based tumor therapy

Biomater. Sci., 2024, 12,1716-1725
DOI: 10.1039/D3BM01981K, Paper
Zhongming Huang, Tongren Yang, Jie Yu, Yijian Gao, Yuhua Weng, Yuanyu Huang, Shengliang Li
Through molecular screening, ionic liquid-conjugated polymers (IL-CPs) are developed for highly efficient delivery of CRISPR/Cas9 system, which demonstrated high-performance genome editing-based tumor therapy.
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the

A highly tuneable inverse emulsion polymerization for the synthesis of stimuli-responsive nanoparticles for biomedical applications

Biomater. Sci., 2024, 12,1707-1715
DOI: 10.1039/D3BM01765F, Paper
Andrew C. Murphy, Heidi F. Oldenkamp, Nicholas A. Peppas
This article demonstrates an inverse emulsion scheme to polymerize a variety of ionizable and non-ionizable monomers to form stimuli-responsive nanoparticles with potential applications in biomaterials science.
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the

Applications of peptide-based nanomaterials in targeting cancer therapy

Biomater. Sci., 2024, 12,1630-1642
DOI: 10.1039/D3BM02026F, Review Article
Beilei Sun, Limin Zhang, Mengzhen Li, Xin Wang, Weizhi Wang
To meet the precise diagnosis and treatment as well as reduce systemic toxicity and side effects, self-assembled peptides are applied to the targeting therapy, including targeting theranostics, nanocarrier delivery, immunotherapy, and combination therapy.
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the

A microneedle patch realizes weight loss through photothermal induction of fat browning

Biomater. Sci., 2024, 12,1726-1737
DOI: 10.1039/D3BM01767B, Paper
Zichun Gao, Yixuan Liu, Wenjiao Lin, He Lian, Zhaoxu Meng
Hyaluronic acid microneedles loaded with polydopamine nanoparticles induce fat browning, offering innovative localized obesity treatment.
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the

One-pot reaction for the preparation of diatom hemostatic particles with effective hemostasis and economic benefits

Biomater. Sci., 2024, 12,1883-1897
DOI: 10.1039/D3BM01793A, Paper
Yunji Sun, Chang Su, Jinfeng Liu, Zheng He, Shengting Che, Qinglan Wan, Jingyu Cai, Hao Zhan, Chao Feng, Xiaojie Cheng, Feng Lin, Junqiang Wei, Xiguang Chen
Diatom hemostatic particles prepared by one-pot reaction have streamlined process and mass production potential, can significantly stop bleeding and reduce accidental deaths.
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the

Bi-functional quercetin/copper nanoparticles integrating bactericidal and anti-quorum sensing properties for preventing the formation of biofilms

Biomater. Sci., 2024, 12,1788-1800
DOI: 10.1039/D4BM00034J, Paper
Jingjing Cheng, Haixin Zhang, Kunyan Lu, Yi Zou, Dongxu Jia, Hong Yang, Hong Chen, Yanxia Zhang, Qian Yu
A bi-functional antibiofilm nanoplatform was developed based on a complex of quercetin and copper integrating bactericidal and anti-quorum sensing properties.
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the

Copper(II)-based metal–organic framework delivery of calcium ascorbate for enhanced chemodynamic therapy via H2O2 self-supply and glutathione depletion

Biomater. Sci., 2024, 12,1871-1882
DOI: 10.1039/D3BM01922E, Paper
Meng Zhang, Hongjin Xue, Jiaxin Yang, Xin Zhao, Mei Xue, Wei Sun, Jianfeng Qiu, Zhihong Zhu
A Cu/ZIF-8/Vc-Ca/HA nanosystem synchronously releases Fenton catalytic Cu2+ and Vc-Ca to achieve improved chemodynamic therapy via H2O2 self-supply and GSH depletion.
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the

Ferroptosis and ferroptosis-inducing nanomedicine as a promising weapon in combination therapy of prostate cancer

Biomater. Sci., 2024, 12,1617-1629
DOI: 10.1039/D3BM01894F, Review Article
Mengjun Huang, Qiliang Teng, Fei Cao, Jinsheng Huang, Jun Pang
Existing treatments could be sensitized by targeting the ferroptosis pathway in prostate cancer.
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the

Trap & kill: a neutrophil-extracellular-trap mimic nanoparticle for anti-bacterial therapy

Biomater. Sci., 2024, 12,1841-1846
DOI: 10.1039/D4BM00145A, Paper
Jingtao Zheng, Lei Rong, Yao Lu, Jing Chen, Kai Hua, Yongzhong Du, Qiang Zhang, Weishuo Li
A neutrophil-extracellular-trap mimic nanoparticle effectively eliminates bacteria in a trap & kill manner.
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the

Sorafenib and tetrakis (4-carboxyphenyl) porphyrin assembled nanoparticles for synergistic targeted chemotherapy and sonodynamic therapy of hepatocellular carcinoma

Biomater. Sci., 2024, 12,1864-1870
DOI: 10.1039/D3BM01994B, Paper
Yongzhi Chen, Qiuxia Tan, Yuanyu Tang, E. Pang, Rui Peng, Minhuan Lan, Dousheng Bai
Hepatocellular carcinoma (HCC) is characterized by a high degree of malignancy and mortality.
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the

Dynamic monitoring of the fibrosis disease by a collagen targeting near infrared probe

Biomater. Sci., 2024, 12,1924-1931
DOI: 10.1039/D3BM01926H, Paper
Xiaoke Zhang, Qianwen Yang, Sensen Zhou, Cheng Li, Xiqun Jiang
A H2O2-sensitive macromolecular optical probe which can effectively bind to collagen was developed for real time noninvasive visualization of fibrotic tissues.
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the

Futuristic Alzheimer's therapy: acoustic-stimulated piezoelectric nanospheres for amyloid reduction

Biomater. Sci., 2024, 12,1801-1821
DOI: 10.1039/D3BM01688A, Paper
Manju Sharma, Samraggi Choudhury, Anand Babu, Varun Gupta, Dipanjan Sengupta, Syed Afroz Ali, Mrunali D. Dhokne, Ashok Kumar Datusalia, Dipankar Mandal, Jiban Jyoti Panda
The graphical abstract portraying the utility of peizoactive polydopamine-coated PVDF nanospheres as potential therapeutic modalities for Alzheimer's disease. The nanospheres induced fibril disaggregation and neuroprotection upon acoustic activation in neural cells and animal model.
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the

Fibromodulin facilitates the osteogenic effect of Masquelet's induced membrane by inhibiting the TGF-β/SMAD signaling pathway

Biomater. Sci., 2024, 12,1898-1913
DOI: 10.1039/D3BM01665J, Paper
Kai Wang, Ming Zhou, Yuanshu Zhang, Yesheng Jin, Yuan Xue, Dong Mao, Yongjun Rui
Schematic illustration of the mechanism by which an IM promotes bone formation. FMOD secreted by the IM promotes osteogenesis of BMSCs and angiogenesis of HUVECs by inhibiting the TGF-β/SMAD signaling pathway, thus facilitating bone formation.
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the

Application of a meshed artificial dermal scaffold and negative-pressure wound therapy in the treatment of full-thickness skin defects: a prospective in vivo study

Biomater. Sci., 2024, 12,1914-1923
DOI: 10.1039/D3BM01675G, Paper
Open Access
Pei Wei, Lijiao Wu, Hongteng Xie, Zhaohong Chen, Rongwei Tan, Zhaorong Xu
A novel meshed ADS combined with NPWT can reduce the risk of scaffold-related complications, which helps to improve the quality of wound repair and promotes a broader range of applications.
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the

Janus hydrogels: merging boundaries in tissue engineering for enhanced biomaterials and regenerative therapies

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D3BM01875J, Review Article
Yingxue Jiang, Chenhui Zhu, Xiaoxuan Ma, Daidi Fan
In recent years, the design and synthesis of Janus hydrogels have advanced significantly, overcoming single-performance material limitations and broadening applications in tissue engineering and regenerative medicine.
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The unexplored role of alkali and alkaline earth elements (ALAEs) on the structure, processing, and biological effects of bioactive glasses

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D3BM01338C, Review Article
Open Access
Adam Shearer, Matthew Molinaro, Maziar Montazerian, Jessica J. Sly, Marta Miola, Francesco Baino, John C. Mauro
Alkali and alkaline earth elements play a crucial role in the structure, processing, and properties of bioactive glasses, widely used in medical applications since their inception in 1969.
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the

Light-inducible nanodrug-mediated photodynamic and anti-apoptotic synergy for enhanced immunotherapy in triple-negative breast cancer

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00083H, Paper
Jing Huang, Xingliang Liu, Minzhao Lin, Zecong Xiao, Xintao Shuai
An ROS-labile nanodrug co-encapsulating Ce6 and a Bcl-2 inhibitor enabled PDT and reversed apoptotic resistance, demonstrating a potent inhibitory effect on tumor growth.
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