year A 52-Year-Old Woman With Hypertension and Diabetes Who Presents With Chest Pain By clinical.diabetesjournals.org Published On :: 2007-07-01 George D. HarrisJul 1, 2007; 25:115-118Case Studies Full Article
year Plasma and Dietary Linoleic Acid and 3-Year Risk of Type 2 Diabetes After Myocardial Infarction: A Prospective Analysis in the Alpha Omega Cohort By care.diabetesjournals.org Published On :: 2020-01-20T12:00:30-08:00 OBJECTIVE To study plasma and dietary linoleic acid (LA) in relation to type 2 diabetes risk in post–myocardial infarction (MI) patients. RESEARCH DESIGN AND METHODS We included 3,257 patients aged 60–80 years (80% male) with a median time since MI of 3.5 years from the Alpha Omega Cohort and who were initially free of type 2 diabetes. At baseline (2002–2006), plasma LA was measured in cholesteryl esters, and dietary LA was estimated with a 203-item food-frequency questionnaire. Incident type 2 diabetes was ascertained through self-reported physician diagnosis and medication use. Hazard ratios (with 95% CIs) were calculated by Cox regressions, in which dietary LA isocalorically replaced the sum of saturated (SFA) and trans fatty acids (TFA). RESULTS Mean ± SD circulating and dietary LA was 50.1 ± 4.9% and 5.9 ± 2.1% energy, respectively. Plasma and dietary LA were weakly correlated (Spearman r = 0.13, P < 0.001). During a median follow-up of 41 months, 171 patients developed type 2 diabetes. Plasma LA was inversely associated with type 2 diabetes risk (quintile [Q]5 vs. Q1: 0.44 [0.26, 0.75]; per 5%: 0.73 [0.62, 0.86]). Substitution of dietary LA for SFA+TFA showed no association with type 2 diabetes risk (Q5 vs. Q1: 0.78 [0.36, 1.72]; per 5% energy: 1.18 [0.59, 2.35]). Adjustment for markers of de novo lipogenesis attenuated plasma LA associations. CONCLUSIONS In our cohort of post-MI patients, plasma LA was inversely related to type 2 diabetes risk, whereas dietary LA was not related. Further research is needed to assess whether plasma LA indicates metabolic state rather than dietary LA in these patients. Full Article
year Similar Breast Cancer Risk in Women Older Than 65 Years Initiating Glargine, Detemir, and NPH Insulins By care.diabetesjournals.org Published On :: 2020-03-20T11:50:34-07:00 OBJECTIVE To assess whether initiation of insulin glargine (glargine), compared with initiation of NPH or insulin detemir (detemir), was associated with an increased risk of breast cancer in women with diabetes. RESEARCH DESIGN AND METHODS This was a retrospective new-user cohort study of female Medicare beneficiaries aged ≥65 years initiating glargine (203,159), detemir (67,012), or NPH (47,388) from September 2006 to September 2015, with follow-up through May 2017. Weighted Cox proportional hazards regression was used to estimate hazard ratios (HRs) and 95% CIs for incidence of breast cancer according to ever use, cumulative duration of use, cumulative dose of insulin, length of follow-up time, and a combination of dose and length of follow-up time. RESULTS Ever use of glargine was not associated with an increased risk of breast cancer compared with NPH (HR 0.97; 95% CI 0.88–1.06) or detemir (HR 0.98; 95% CI 0.92–1.05). No increased risk was seen with glargine use compared with either NPH or detemir by duration of insulin use, length of follow-up, or cumulative dose of insulin. No increased risk of breast cancer was observed in medium- or high-dose glargine users compared with low-dose users. CONCLUSIONS Overall, glargine use was not associated with an increased risk of breast cancer compared with NPH or detemir in female Medicare beneficiaries. Full Article
year Iowa man receives postcard mailed 33 years earlier By www.upi.com Published On :: Thu, 07 May 2020 13:35:11 -0400 An Iowa man who received a postcard from his sister said he was surprised to note the card had been mailed in 1987. Full Article
year Watch: Utah man reunited with class ring 38 years after it was lost in Germany By www.upi.com Published On :: Thu, 07 May 2020 15:42:56 -0400 A Utah man who lost his high school class ring in Germany in 1982 was reunited with the ring thanks to a man who found it on a beach in the United States. Full Article
year Fortune cookie numbers earn $2 million lottery jackpot after 5 years By www.upi.com Published On :: Thu, 07 May 2020 15:48:47 -0400 A North Carolina man said the lottery numbers he took from a fortune cookie earned him a $2 million jackpot after five years of using them to play Mega Millions. Full Article
year Lipid and Inflammatory Cardiovascular Risk Worsens Over 3 Years in Youth With Type 2 Diabetes: The TODAY clinical trial By care.diabetesjournals.org Published On :: 2013-06-01 TODAY Study GroupJun 1, 2013; 36:1758-1764TODAY Study Full Article
year Update on Cardiovascular Outcomes at 30 Years of the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study By care.diabetesjournals.org Published On :: 2014-01-01 John M. LachinJan 1, 2014; 37:39-43DCCT/EDIC 30th Anniversary Summary Findings Full Article
year Intensive Diabetes Treatment and Cardiovascular Outcomes in Type 1 Diabetes: The DCCT/EDIC Study 30-Year Follow-up By care.diabetesjournals.org Published On :: 2016-05-01 The Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications (EDIC) Study Research GroupMay 1, 2016; 39:686-693Cardiovascular Disease and Diabetes Full Article
year The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study at 30 Years: Overview By care.diabetesjournals.org Published On :: 2014-01-01 David M. NathanJan 1, 2014; 37:9-16DCCT/EDIC 30th Anniversary Summary Findings Full Article
year Effect of a Lifestyle Intervention Program With Energy-Restricted Mediterranean Diet and Exercise on Weight Loss and Cardiovascular Risk Factors: One-Year Results of the PREDIMED-Plus Trial By care.diabetesjournals.org Published On :: 2019-05-01 Jordi Salas-SalvadóMay 1, 2019; 42:777-788Continuing Evolution of Nutritional Therapy for Diabetes Full Article
year The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study at 30 Years: Overview By care.diabetesjournals.org Published On :: 2014-01-01 David M. NathanJan 1, 2014; 37:9-16DCCT/EDIC 30th Anniversary Summary Findings Full Article
year 2019 marks big year for Washington office By www.ada.org Published On :: Thu, 23 Jan 2020 11:56:00 -0600 The Association’s Washington office covered a wide range of advocacy issues in 2019 — from vaping to student loan reform to making sure dentistry was exempt from the U.S. Mexico-Tourism Act. Full Article
year After 3 years, Find-a-Dentist initiative a ‘success’ By www.ada.org Published On :: Mon, 10 Feb 2020 15:06:00 -0600 Of the more than 3 million profile views, the program found that 17% resulted in action, which include potential patients visiting a dentist’s website, calling or emailing the practice and sharing their profile. Industry average for similar sites is only 1-4%, so patients are nearly six times more likely to contact an ADA dentist through Find-a-Dentist. Full Article
year EIA sees fuel prices below 2018 average for the next two years By www.upi.com Published On :: Thu, 17 Jan 2019 08:11:18 -0500 U.S. retail fuel prices will drop this year and in 2020 from 2018, but in both cases higher than January levels due to mandated lower sulfur in marine fuel. Full Article
year Suicide risk high in first year after brain cancer diagnosis By www.upi.com Published On :: Fri, 01 May 2020 13:28:09 -0400 People with brain cancer are at increased risk for suicide compared to the general population, particularly within the first year following diagnosis, a new analysis has found. Full Article
year Erratum. Predicting 10-Year Risk of End-Organ Complications of Type 2 Diabetes With and Without Metabolic Surgery: A Machine Learning Approach. Diabetes Care 2020;43:852-859 By care.diabetesjournals.org Published On :: 2020-04-15T14:26:52-07:00 Full Article
year Astronauts anticipate first crewed launch from U.S. soil in nine years By www.upi.com Published On :: Fri, 01 May 2020 18:15:49 -0400 The two astronauts who are to begin a new era of human spaceflight from U.S. soil this month said Friday they hope to inspire generations of Americans. Full Article
year Astronomers find black hole just 1,000 light-years from Earth By www.upi.com Published On :: Wed, 06 May 2020 15:35:41 -0400 Scientists have discovered the closest black hole to Earth, located just 1,000 light-years away. Full Article
year Trump’s First Year on Immigration Policy: Rhetoric vs. Reality By www.migrationpolicy.org Published On :: Wed, 17 Jan 2018 11:51:07 -0500 Looking back after one year in office, it is striking how just closely the Trump administration’s actions on immigration have hewed to priorities Donald Trump outlined in an uncommonly detailed policy speech in August 2016. This report revisits those pledges to assess where the administration has made the most and least headway, and what its policy agenda ahead might look like. Full Article
year [ Marriage & Divorce ] Open Question : 5 year old doesn’t want to go to her dads? By answers.yahoo.com Published On :: Sat, 09 May 2020 17:24:30 +0000 My step daughter is 5 and her dad lives states away. He calls her maybe once a month (not even on holidays) he hasn’t had her since she was one (when they lived in the same state) he had told my wife if our daughter wanted to see him we could bring her to him but he wasn’t coming to our state. My wife asked him beginning of this year if he’d sign his rights over. He doesn’t talk to her and he was behind on child support. He said no and that we was going to finally pick her up. He is getting married and didn’t include the little one we told him if he is going to get her he needs to tell her that it’s not just him living there and he is getting married. Our daughter was hurt by it that he hid this from her (they’ve been engaged for 4 years). She’s been crying she doesn’t want to go and he isn’t willing to come stay the week here to visit. He said he is taking her back to his state for a month. Yes it’s in their agreement but is there anything we can do? She really doesn’t want to go to a “strangers” house is what my daughter says. Full Article
year Immigration-Related Policy Changes in the First Two Years of the Trump Administration By www.migrationpolicy.org Published On :: Mon, 06 May 2019 16:16:15 -0400 In the two years since President Trump entered office, U.S. immigration policy has changed in many ways. Some actions have received significant media attention and public scrutiny, and others have been implemented with little fanfare. This document chronicles these wide-reaching policy changes, covering immigration enforcement, the immigration courts, humanitarian admissions, visa processing, and more. Full Article
year Dear first year, this isn’t something you can plan for (Part 3) By blogs.ams.org Published On :: Wed, 15 Jan 2020 15:00:57 +0000 In case you want to catch up: here are Parts 1 & 2 of my first-year journey. We like to think that our life stories have happy endings, perhaps that we can carefully partition our lives into fourths of each … Continue reading → Full Article Advice Grad School Grad student life Starting Grad Schol Uncategorized
year Genetic Susceptibility Determines {beta}-Cell Function and Fasting Glycemia Trajectories Throughout Childhood: A 12-Year Cohort Study (EarlyBird 76) By care.diabetesjournals.org Published On :: 2020-02-20T11:55:30-08:00 OBJECTIVE Previous studies suggested that childhood prediabetes may develop prior to obesity and be associated with relative insulin deficiency. We proposed that the insulin-deficient phenotype is genetically determined and tested this hypothesis by longitudinal modeling of insulin and glucose traits with diabetes risk genotypes in the EarlyBird cohort. RESEARCH DESIGN AND METHODS EarlyBird is a nonintervention prospective cohort study that recruited 307 healthy U.K. children at 5 years of age and followed them throughout childhood. We genotyped 121 single nucleotide polymorphisms (SNPs) previously associated with diabetes risk, identified in the adult population. Association of SNPs with fasting insulin and glucose and HOMA indices of insulin resistance and β-cell function, available from 5 to 16 years of age, were tested. Association analysis with hormones was performed on selected SNPs. RESULTS Several candidate loci influenced the course of glycemic and insulin traits, including rs780094 (GCKR), rs4457053 (ZBED3), rs11257655 (CDC123), rs12779790 (CDC123 and CAMK1D), rs1111875 (HHEX), rs7178572 (HMG20A), rs9787485 (NRG3), and rs1535500 (KCNK16). Some of these SNPs interacted with age, the growth hormone–IGF-1 axis, and adrenal and sex steroid activity. CONCLUSIONS The findings that genetic markers influence both elevated and average courses of glycemic traits and β-cell function in children during puberty independently of BMI are a significant step toward early identification of children at risk for diabetes. These findings build on our previous observations that pancreatic β-cell defects predate insulin resistance in the onset of prediabetes. Understanding the mechanisms of interactions among genetic factors, puberty, and weight gain would allow the development of new and earlier disease-management strategies in children. Full Article
year Predicting 10-Year Risk of End-Organ Complications of Type 2 Diabetes With and Without Metabolic Surgery: A Machine Learning Approach By care.diabetesjournals.org Published On :: 2020-03-20T11:50:34-07:00 OBJECTIVE To construct and internally validate prediction models to estimate the risk of long-term end-organ complications and mortality in patients with type 2 diabetes and obesity that can be used to inform treatment decisions for patients and practitioners who are considering metabolic surgery. RESEARCH DESIGN AND METHODS A total of 2,287 patients with type 2 diabetes who underwent metabolic surgery between 1998 and 2017 in the Cleveland Clinic Health System were propensity-matched 1:5 to 11,435 nonsurgical patients with BMI ≥30 kg/m2 and type 2 diabetes who received usual care with follow-up through December 2018. Multivariable time-to-event regression and random forest machine learning models were built and internally validated using fivefold cross-validation to predict the 10-year risk for four outcomes of interest. The prediction models were programmed to construct user-friendly web-based and smartphone applications of Individualized Diabetes Complications (IDC) Risk Scores for clinical use. RESULTS The prediction tools demonstrated the following discrimination ability based on the area under the receiver operating characteristic curve (1 = perfect discrimination and 0.5 = chance) at 10 years in the surgical and nonsurgical groups, respectively: all-cause mortality (0.79 and 0.81), coronary artery events (0.66 and 0.67), heart failure (0.73 and 0.75), and nephropathy (0.73 and 0.76). When a patient’s data are entered into the IDC application, it estimates the individualized 10-year morbidity and mortality risks with and without undergoing metabolic surgery. CONCLUSIONS The IDC Risk Scores can provide personalized evidence-based risk information for patients with type 2 diabetes and obesity about future cardiovascular outcomes and mortality with and without metabolic surgery based on their current status of obesity, diabetes, and related cardiometabolic conditions. Full Article
year Persistence of Continuous Glucose Monitoring Use in a Community Setting 1 Year After Purchase By clinical.diabetesjournals.org Published On :: 2013-07-01 James ChamberlainJul 1, 2013; 31:106-109Feature Articles Full Article
year Schools in Massachusetts to Remain Closed for Rest of Year By feedproxy.google.com Published On :: Tue, 21 Apr 2020 00:00:00 +0000 School buildings in Massachusetts will remain closed through the end of the academic year, but remote learning will continue, Gov. Charlie Baker announced Tuesday. Full Article Massachusetts
year North Carolina public schools closed for rest of school year By feedproxy.google.com Published On :: Mon, 27 Apr 2020 00:00:00 +0000 Full Article North_Carolina
year Schools closed for rest of academic year amid virus threat By feedproxy.google.com Published On :: Wed, 22 Apr 2020 00:00:00 +0000 Full Article Virginia
year Planning process for Arizona's next school year underway By feedproxy.google.com Published On :: 2020-05-02T17:43:47-04:00 Full Article Education
year New Jersey schools to stay closed for rest of academic year By feedproxy.google.com Published On :: 2020-05-04T16:48:45-04:00 Full Article Education
year Gay teacher ousted from Catholic school after 23 years By feedproxy.google.com Published On :: 2020-05-04T22:56:59-04:00 Full Article Education
year Lamont canceling in-person classes for rest of school year By feedproxy.google.com Published On :: 2020-05-05T23:44:20-04:00 Full Article Education
year School-Year Closures Now Affect 50 Million Students By feedproxy.google.com Published On :: Thu, 07 May 2020 00:00:00 +0000 Maryland's announcement Wednesday that school buildings won't reopen this academic year marked a a sobering milestone in the disruption to American education caused by the coronavirus pandemic. Full Article Wyoming
year Some Wyoming schools decide to remain closed for year By feedproxy.google.com Published On :: Tue, 28 Apr 2020 00:00:00 +0000 Full Article Wyoming
year Feds: No Penalties for Nevada After Smarter Balanced Testing Woes Last Year By feedproxy.google.com Published On :: Thu, 17 Mar 2016 00:00:00 +0000 The state requested a waiver from the federal requirement in January. Failure to meet the 95-percent requirement can lead to funding penalties for states. Full Article North_Dakota
year Beshear: Schools to stay closed for rest of academic year By feedproxy.google.com Published On :: Tue, 21 Apr 2020 00:00:00 +0000 Full Article Kentucky
year New York City Schools Will Stay Closed for Academic Year, Mayor Says By feedproxy.google.com Published On :: Sat, 11 Apr 2020 00:00:00 +0000 Gov. Andrew Cuomo pushed back on the Mayor Bill de Blasio's announcement, however, saying "no decision" had been made about reopening schools in New York City or elsewhere in the state. Full Article New_York
year School Closures for Coronavirus Could Extend to the End of School Year, Some Say By feedproxy.google.com Published On :: Sun, 15 Mar 2020 00:00:00 +0000 More than half of all states have ordered schools closed for multiple weeks to help slow the pandemic. Full Article New_York
year Planning process for Arizona's next school year underway By feedproxy.google.com Published On :: 2020-05-04T08:42:11-04:00 Full Article Education
year New Jersey schools to stay closed for rest of academic year By feedproxy.google.com Published On :: 2020-05-04T15:09:00-04:00 Full Article Education
year Gay teacher ousted from Catholic school after 23 years By feedproxy.google.com Published On :: 2020-05-05T08:38:08-04:00 Full Article Education
year Lamont canceling in-person classes for rest of school year By feedproxy.google.com Published On :: 2020-05-06T08:43:51-04:00 Full Article Education
year School-Year Closures Now Affect 50 Million Students By feedproxy.google.com Published On :: Thu, 07 May 2020 00:00:00 +0000 Maryland's announcement Wednesday that school buildings won't reopen this academic year marked a a sobering milestone in the disruption to American education caused by the coronavirus pandemic. Full Article Montana
year New Jersey schools to stay closed for rest of academic year By feedproxy.google.com Published On :: Mon, 04 May 2020 00:00:00 +0000 Full Article New_Jersey
year Utah becomes latest state to cancel rest of school year By feedproxy.google.com Published On :: Wed, 15 Apr 2020 00:00:00 +0000 Full Article Utah
year Schools ordered to remain closed until end of academic year By feedproxy.google.com Published On :: Thu, 09 Apr 2020 00:00:00 +0000 Full Article Pennsylvania
year The Year in Personalized Learning: 2017 in Review By feedproxy.google.com Published On :: Thu, 21 Dec 2017 00:00:00 +0000 The Chan Zuckerberg Initiative, states like Vermont and Rhode Island, and companies such as AltSchool all generated headlines about personalized learning in 2017. Full Article Rhode_Island
year Lamont canceling in-person classes for rest of school year By feedproxy.google.com Published On :: Wed, 06 May 2020 00:00:00 +0000 Full Article Connecticut
year Georgia Leader Chosen as National 2019 Superintendent of the Year By feedproxy.google.com Published On :: Fri, 15 Feb 2019 00:00:00 +0000 Curtis Jones, a U.S. Army veteran, has led Georgia's Bibb County school system since 2015. Full Article Georgia
