The "John Evenson" tugboat was helping another ship enter the Sturgeon Bay Ship Canal in Wisconsin when it sank to the bottom of Lake Michigan in 1895

While the annual shower usually makes for a sleepy showing, it has been known to produce fantastic outbursts in the past

The 4,000-year-old burial chamber featured hieroglyphs referring to the woman, known as Idi, as the "lady of the house"

The success is a giant leap toward the company's goal to take humans and cargo all the way to Mars on the world's biggest and most powerful launch vehicle

A scientist used at-home experiments to test whether cats hesitated when moving through increasingly shorter or narrower openings

The banana duct-taped to a wall was created to be a "reflection on what we value." An upcoming auction may deliver an answer

The deep penetrations suggest that the feline was pressing its claws into the clay, a behavior sometimes known as "making biscuits"

Some 250 volunteers transported more than 2,000 books

As Week 3 of the provincial election campaign begins, there are questions about how Nova Scotia's major political parties plan to combat the rising number of opioid overdose deaths. 

Building highways isn't the only solution to the growing problem of traffic congestion in and around the Halifax Regional Municipality, says the head of an organization that advocates for rail-based public transit.

Mosquitoes take blood meals from a diverse range of host animals and their host associations vary by species. Characterizing these associations is an important element of the transmission dynamics of mosquito-vectored pathogens. To characterize mosquito host associations, various molecular techniques have been developed, which are collectively referred to as blood meal analysis. DNA barcoding has diverse biological applications and is well-suited to mosquito blood meal analysis. The standard DNA barcoding marker for animals is a 5' fragment of the cytochrome c oxidase I (COI) gene. A major advantage of this marker is its taxonomic coverage in DNA sequence reference databases, making it feasible to identify a wider range of mosquito host species than with any other gene. However, the COI gene contains high sequence variation at potential priming sites between vertebrate orders. Coupled with the need for primer sequences to be mismatched with mosquito priming sites so that annealing to mosquito DNA is inhibited, it can be difficult to design primers suitable for blood meal analysis applications. Several primers are available that perform well in mosquito blood meal analysis, annealing to priming sites for most vertebrate host taxa, but not to those of mosquitoes. Because priming site sequence variation among vertebrate taxa can cause amplification to fail, a hierarchical approach to DNA barcoding-based blood meal analysis can be applied. In such an approach, no single primer set is expected to be effective for 100% of potential host species. If amplification fails in the initial reaction, a subsequent reaction is attempted with primers that anneal to different priming sites, and so on, until amplification is successful.

The insect eggshell is a multifunctional structure with several important roles, including generating an entry point for sperm via the micropyle before oviposition, serving as an oviposition substrate attachment surface, and functioning as a protective layer during embryo development. Eggshell proteins play major roles in eggshell tanning and hardening following oviposition and provide molecular cues that define dorsal–ventral axis formation. Precise eggshell formation during ovarian follicle maturation is critical for normal embryo development and the synthesis of a defective eggshell often gives rise to inviable embryos. Therefore, simple and accurate methods for identifying eggshell proteins will facilitate our understanding of the molecular pathways regulating eggshell formation and the mechanisms underlying normal embryo development. This protocol describes how to isolate and enrich eggshells from mature oocytes of Aedes aegypti mosquitoes and how to extract their eggshell proteins for liquid chromatography with tandem mass spectrometry (LC–MS/MS) proteomic analysis. Although this methodology was developed for studying mosquito eggshells, it may be applicable to eggs from a variety of insects. Mosquitoes are ideal model organisms for this study as their ovarian follicle development and eggshell formation are meticulously regulated by blood feeding and their follicles develop synchronously throughout oogenesis in a time-dependent manner.

Advocates say pay equity laws, while needed, often do not help the most vulnerable workers.

Eight years ago, a woman filed a complaint about two RCMP constables in Moncton. She accused them of having "an improper and racist attitude" and of discriminating against her and her husband during an investigation into a stolen truck and trailer. 

Roughly 30 percent of Catalonia is protected land making it a stunning place to hit the trails

In the new year, Ontario is supposed to be fully accessible for disabled people, but advocates say the province is ‘nowhere near’ meeting standards it created 20 years ago.

Bo Levi Mitchell is a CFL all-star for the third time. The Hamilton Tiger-Cats quarterback and East Division finalist for the CFL's outstanding player award was named to the 2024 all-star squad on Thursday.

Here comes Santa Claus! There are a number of parades set to take place in November and December both during the day and in the evening. Here's a list of where you can find the big man in red.

Midway through her second term as a public school board trustee in Windsor-Essex, Sarah Cipkar is resigning for what she calls mainly “personal and professional” reasons.

A Syilx Okanagan woman has filed a lawsuit against church authorities and the Canadian government alleging she was physically and sexually abused as a child at a Catholic-run Vernon, B.C., school.

A young Toronto Maple Leafs fan has caught the attention of the NHL with his Halloween costume this year. With the help of his dad, Grayson Haire, of Trenton, Ont., will wear a 3D version of an Upper Deck MVP Auston Matthews hockey card.

Newly announced mixed doubles duo Rachel Homan and John Morris, skips Jennifer Jones and Brad Gushue, and broadcasters Mike Harris, Joanne Courtney and Bruce Rainnie all break down a busy week in curling news.

R&D ‘Sandbox’ Previews Some Potential Capabilities for 3D CAD Software

New Licensing, Support Programs For Certification Accompany Software Upgrades

SolidWorks CAD Software Enables Engineering Students to Fit ‘CubeSat’ Components Into a Four-Inch Square Box

Fabricators & Manufacturers Association teams with SolidWorks to encourage students to get formal manufacturing training

U.K.

3,200 German vocational students in 30 colleges learn engineering fundamentals and prepare for professional careers with SolidWorks software

Automation systems provider also streamlines product design and analysis with SolidWorks 3D mechanical design and COSMOS design analysis software

SolidWorks 3D mechanical design and COSMOS design analysis software prepare students for careers at global enterprises

Electronics air filter manufacturer sees dramatic 30 percent increase in Web site traffic, reduces customer product development by two months

Company's Linear Motion and Assembly Technologies Group increases sales by 40 percent, leads by 25 percent, with redesigned Web site featuring downloadable 3D models

Customized valve and cylinder maker sees 420 percent increase in online transactions in the first three months

Students cut 20 percent out of initial project development time with SolidWorks 3D modeling and COSMOS design analysis software

SolidWorks Education Edition prepares students for engineering careers with SolidWorks 3D mechanical design and COSMOS analysis software

T-slotted frame manufacturer responds to market demand for downloadable 3D models

Motion control product leader to cut custom part configuration from days to minutes

Strong education programs, key sponsorships, and intuitive software put company on top

Aarhus purchases 500 licenses of SolidWorks 3D CAD and COSMOS design analysis software to teach students engineering fundamentals

Expanded 3D CAD curriculum gives instructors more time for individual instruction and special projects

U.K.

Motor manufacturer experiences 50 percent increase in Web site traffic from potential customers in first month using 3D-enabled online catalog

Students will begin learning 3D mechanical design as early as seventh grade

Enhanced online parts library addresses growing global demand for online design content

Test enables teachers, potential employers to evaluate students' modeling skills as well as their grasp of engineering principles

Students in 500 second level schools across the country will learn fundamental engineering and design skills with easy-to-learn 3D CAD software

Schools combine SOLIDWORKS 3D CAD software with 3D scanning and printing to enrich student learning

Japanese university teaches mechanical engineering using SOLIDWORKS 3D CAD and COSMOS design analysis software

Students design real-world projects such as a moveable floor on a floating hospital in South America using SOLIDWORKS 3D CAD and COSMOS design analysis software