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Protein cages and virus-like particles: from fundamental insight to biomimetic therapeutics

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00159G, Minireview
Nicole F. Steinmetz, Sierin Lim, Frank Sainsbury
Protein cages found in nature have evolved for a variety of purposes and this review focuses on how they are being co-opted for use in immunotherapy and therapeutic delivery.
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Self-assembled nucleo-tripeptide hydrogels provide local and sustained doxorubicin release

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00134A, Paper
Kiheon Baek, Alexander David Noblett, Pengyu Ren, Laura J. Suggs
Doxorubicin is intercalated within the nanofibril structure of self-assembled nucleo-peptide hydrogels and injection leads to decrease in tumor volume and greater concentration of chemotherapeutic relative to soluble form.
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ZBTB20-mediated titanium particle-induced peri-implant osteolysis by promoting macrophage inflammatory responses

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00147C, Paper
Open Access
Junxiong Qiu, Peng Peng, Min Xin, Zhenkang Wen, Zhong Chen, Sipeng Lin, Manyuan Kuang, Yuan Fu, Guibin Fang, Shixun Li, Changchuan Li, Jiaji Mao, Ling Qin, Yue Ding
Aseptic loosening (AL) caused by wear particles released from implant surfaces is one of the main causes for the failure of artificial joints, which is initiated by macrophage inflammatory responses.
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Oral biofilm elimination by combining iron-based nanozymes and hydrogen peroxide-producing bacteria

Biomater. Sci., 2020, 8,2447-2458
DOI: 10.1039/C9BM01889A, Paper
Yanqiu Wang, Xinyu Shen, Shang Ma, Qianqian Guo, Wei Zhang, Lu Cheng, Liming Ding, Zhuobin Xu, Jing Jiang, Lizeng Gao
Combining nanozymes and bacteria to eliminate dental biofilms in a mixed-species model.
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A riboflavin–ultraviolet light A-crosslinked decellularized heart valve for improved biomechanical properties, stability, and biocompatibility

Biomater. Sci., 2020, 8,2549-2563
DOI: 10.1039/C9BM01956A, Paper
Chungeng Liu, Weihua Qiao, Hong Cao, Jinchi Dai, Fei Li, Jiawei Shi, Nianguo Dong
Riboflavin–ultraviolet light A could effectively crosslink a decellularized heart valve to improve its biomechanical properties, stability and biocompatibility.
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Enhanced selectivity, cellular uptake, and in vitro activity of an intrinsically fluorescent copper–tirapazamine nanocomplex for hypoxia targeted therapy in prostate cancer

Biomater. Sci., 2020, 8,2420-2433
DOI: 10.1039/C9BM01905G, Paper
Vera L. Silva, Abdessamad Kaassis, Ashkan Dehsorkhi, Cédrik-Roland Koffi, Maja Severic, Moustafa Abdelhamid, Duuamene Nyimanu, Christopher J. Morris, Wafa’ T. Al-Jamal
Cu(TPZ)2 complex as a promising hypoxia selective cytotoxin in prostate cancer.
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Nanomedicine – a promising therapy for hematological malignancies

Biomater. Sci., 2020, 8,2376-2393
DOI: 10.1039/D0BM00129E, Review Article
Lifen Huang, Jun Huang, Junbin Huang, Hongman Xue, Zhiqing Liang, Jun Wu, Chun Chen
Nanoparticles (NPs) are used for the diagnosis and treatment of hematological tumors by loading various pharmacodynamic molecules.
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A thermo-responsive, self-assembling biointerface for on demand release of surface-immobilised proteins

Biomater. Sci., 2020, 8,2673-2681
DOI: 10.1039/C9BM01957J, Paper
Angela Saccardo, Mikhail Soloviev, Enrico Ferrari
Engineering of the neuronal SNARE proteins yields chimeric bio-materials that reversibly assemble and disassemble at set temperatures.
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The electrospinning of a thermo-responsive polymer with peptide conjugates for phenotype support and extracellular matrix production of therapeutically relevant mammalian cells

Biomater. Sci., 2020, 8,2611-2626
DOI: 10.1039/C9BM01965K, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
F. A. A. Ruiter, L. E. Sidney, K. L. Kiick, J. I. Segal, C. Alexander, F. R. A. J. Rose
The fabrication and application of a biocompatible peptide conjugated thermo-responsive fibrous scaffolds for cellular phenotype support and enzymatic-free passaging of mammalian cells.
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Highly responsive and rapid hydrogen peroxide-triggered degradation of polycaprolactone nanoparticles

Biomater. Sci., 2020, 8,2394-2397
DOI: 10.1039/C9BM02019E, Communication
Peng-Hao Hsu, Carina Arboleda, Alexandra Stubelius, Ling-Wei Li, Jason Olejniczak, Adah Almutairi
Nanoparticles formulated from fast-degrading oxidation-responsive polycaprolactone are responsive to 50 μM of H2O2.
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A multifunctional metal-biopolymer coordinated double network hydrogel combined with multi-stimulus responsiveness, self-healing, shape memory and antibacterial properties

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00425A, Paper
Kun Yan, Feiyang Xu, Chunyu Wang, Yingying Li, Yuanli Chen, Xiufang Li, Zhentan Lu, Dong Wang
A universal, straightforward macroscale assembly technology has been presented for fabrication of polysaccharide-based multifunctional DN gels based on metal coordination chemistry.
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A versatile ultrafine and super-absorptive H+-modified montmorillonite: application for metabolic syndrome intervention and gastric mucosal protection

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00474J, Paper
Qiwen Wang, Jie Shen, Enqi Mo, Haotian Zhang, Jianwei Wang, Xiurong Hu, Jun Zhou, Hongzhen Bai, Guping Tang
An H+-modified montmorillonite (H-MMT) was prepared using an acid modification method to obtain powerful absorption ability as a theranostic platform for both metabolic syndrome and gastric mucosa protection.
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Surface engineering of titanium alloy using metal-polyphenol network coating with magnesium ions for improved osseointegration

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00566E, Paper
Sangmin Lee, Yun-Young Chang, Jinkyu Lee, Sajeesh Kumar Madhurakkat Perikamana, Eun Mi Kim, Yang-Hun Jung, Jeong-Ho Yun, Heungsoo Shin
Although titanium-based implants are widely used in orthopedic and dental clinics, improved osseointegration at the bone–implant interface is still required.
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Prometryn induces apoptotic cell death through cell cycle arrest and oxidative DNA damage

Toxicol. Res., 2019, 8,833-841
DOI: 10.1039/C9TX00080A, Paper
Qiaoyun Liu, Longsheng Wang, Hanwen Chen, Bo Huang, Jiawei Xu, Ying Li, Paul Héroux, Xinqiang Zhu, Yihua Wu, Dajing Xia
Prometryn induces oxidative stress-mediated DNA damage; Prometryn induces S phase of cell cycle arrest; Prometryn induces Bax-dependent apoptosis in BEAS-2B cells.
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Cadmium telluride quantum dot-exposed human bronchial epithelial cells: a further study of the cellular response by proteomics

Toxicol. Res., 2019, 8,994-1001
DOI: 10.1039/C9TX00126C, Paper
Yan-Ming Xu, Heng Wee Tan, Wei Zheng, Zhan-Ling Liang, Fei-Yuan Yu, Dan-Dan Wu, Yue Yao, Qiu-Hua Zhong, Rui Yan, Andy T. Y. Lau
A comparative proteome analysis was conducted to identify global changes in the protein expression profiles of cadmium telluride quantum dot-exposed human bronchial epithelial BEAS-2B cells.
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Synergistic antioxidant capacity of CsNPs and CurNPs against cytotoxicity, genotoxicity and pro-inflammatory mediators induced by hydroxyapatite nanoparticles in male rats

Toxicol. Res., 2019, 8,939-952
DOI: 10.1039/C9TX00221A, Paper
Israa F. Mosa, Mokhtar Youssef, Maher Kamel, Osama F. Mosa, Yasser Helmy
Due to their dynamic characteristics, hydroxyapatite nanoparticles (HAP-NPs) have been employed numerous times in nanomedicine and in tissue engineering, particularly as diagnostic and therapeutic agents.
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Phytochemicals protect L02 cells against hepatotoxicity induced by emodin via the Nrf2 signaling pathway

Toxicol. Res., 2019, 8,1028-1034
DOI: 10.1039/C9TX00220K, Paper
Yan Yan, Kang Wang, Xu Tang, Jun-feng Gao, Bin-yu Wen
Dihydromyricetin (DMY), hyperoside and silybin are phytochemicals that belong to a class called flavonoids, and they have been used in liver protection pharmaceutical preparations, but the specific mechanism of these chemicals is still unclarified.
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The protective effect of thymoquinone on tert-butylhydroquinone induced cytotoxicity in human umbilical vein endothelial cells

Toxicol. Res., 2019, 8,1050-1056
DOI: 10.1039/C9TX00235A, Paper
Zahra Karimi, Maryam Ghaffari, Jafar Ezzati Nazhad Dolatabadi, Parvin Dehghan
2-tert-Butyl-4-hydroquinone (TBHQ) is used for inhibition of oxidative rancidity in the food industry.
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India's credit profile to face further pressure due to Covid-19: Moody's

Moody's rating on the government of India is Baa2 with negative outlook




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Vizag gas leak: NGT orders LG Polymers to deposit Rs 50 cr pending probe

NGT bench set up fact-finding committee, to be headed by former AP High Court judge




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Probing permanent dipoles in CdSe nanoplatelets with transient electric birefringence

Nanoscale, 2020, Advance Article
DOI: 10.1039/D0NR00884B, Paper
Ivan Dozov, Claire Goldmann, Patrick Davidson, Benjamin Abécassis
Transient electric birefringence experiments with colloidal suspensions of zinc-blende CdSe semiconducting nanoplatelets prove that these particles bear a large ground-state electric dipole despite the cubic structure of bulk zinc-blende CdSe.
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Hybrid Phase 1T/2H-MoS2 with Controllable 1T Concentration and Its Promoted Hydrogen Evolution Reaction

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR02525A, Paper
Yuxiao Zhang, Yasutaka Kuwahara, Kohsuke Mori, Catherine Louis, Hiromi Yamashita
MoS2 has been investigated as a low-cost alternative to Pt in electrochemical hydrogen evolution reaction. One of the promising method to further activate MoS2 is phase engineering. MoS2 generally exhibit...
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A super stable assembled P nanowire with variant structural and magnetic/electronic properties via transition metal adsorption

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR02176H, Paper
Sukai Wang, Jinxing Gu, Yinan Dong, Linwei Sai, Fengyu Li
By means of first-principles calculations, we systematically investigated the structure, stability, magnetic and electronic properties of one-dimensional P nanowire (1D-P10 NW) assembled by Pn subunits (n = 2, 8) and...
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Facile fabrication of sponge-like porous micropillar arrays via an electrochemical process

Nanoscale, 2020, Advance Article
DOI: 10.1039/D0NR01518K, Paper
Deyin Zheng, Chang-Hwan Choi, Xin Zhao, Guangyi Sun
Highly ordered and aligned pore structures perpendicular to the exposed surfaces are achieved on the surfaces of 3D Si microstructures.
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Proton exchange membrane with plasmon-active surface for enhancement of fuel cell effectivity

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR00295J, Paper
Roman Elashnikov, Kristina Zahorjanova, Elena Miliutina, Zdenka Kolska, Miroslav Cieslar, Václav Švorčík, Oleksiy Lyutakov
The action of fuel cells with proton-exchanged membrane (PEM) requires the implementation of hydrogen oxidation reaction (HOR) and oxygen reduction reaction (ORR) on the opposite sides of PEM. Recently, based...
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Self-responsive co-delivery system for remodeling tumor intracellular microenvironment to promote PTEN-mediated anti-tumor therapy

Nanoscale, 2020, 12,9392-9403
DOI: 10.1039/D0NR00563K, Paper
Yifei Wang, Ruiting Wang, Sixuan Wu, Jingyi An, Yan Liang, Lin Hou, Zhenzhong Zhang
Delivering the pten gene into tumor cells to reacquire PTEN functionality is considered to be an attractive method for cancer treatment.
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Ionic liquid assisted preparation and modulation of the photoluminescence kinetics for highly efficient CsPbX3 nanocrystals with improved stability

Nanoscale, 2020, 12,9569-9580
DOI: 10.1039/D0NR00579G, Paper
Ting Chen, Yanqiao Xu, Zhixiang Xie, Weihui Jiang, Lianjun Wang, Wan Jiang
A facile approach was performed to synthesize CsPbBr3 NCs with the assistance of ionic liquid [Bmim]Br, which could modulate the surface property and enhace the stability of NCs effectively.
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A solution-processed zero-dimensional all-inorganic perovskite scintillator for high resolution gamma-ray spectroscopy detection

Nanoscale, 2020, 12,9727-9732
DOI: 10.1039/D0NR00772B, Paper
Qiang Xu, Juan Wang, Wenyi Shao, Xiao Ouyang, Xiang Wang, Xinlei Zhang, Yong Guo, Xiaoping Ouyang
A zero-dimensional all-inorganic CsPbBr3 nanocrystal embedded Cs4PbBr6 scintillator has been achieved. Owing to the low dimensional quantum effect, this all-inorganic scintillator exhibits desirable scintillation performance.
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Neuron-like cell differentiation of hADSCs promoted by a copper sulfide nanostructure mediated plasmonic effect driven by near-infrared light

Nanoscale, 2020, 12,9833-9841
DOI: 10.1039/D0NR02319A, Paper
Shan Zhang, Min Hao, Wenqiang Gao, Feng Liu, Jiazhi Duan, Ying Kong, Duo Liu, Hong Liu
Neuron-like cell differentiation of hADSCs promoted by a CuS nanostructure mediated plasmonic effect driven by near-infrared light.
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High charge carrier mobility in solution processed one-dimensional lead halide perovskite single crystals and their application as photodetectors

Nanoscale, 2020, 12,9688-9695
DOI: 10.1039/D0NR01495H, Paper
Tianjun Liu, Weidong Tang, Sally Luong, Oliver Fenwick
Large space-charge limited mobility and a fast optical response is reported in low dimensional halide perovskite crystals. A transition between hopping transport and band-like transport is observed at 200 K.
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A novel split mode TFBAR device for quantitative measurements of prostate specific antigen in a small sample of whole blood

Nanoscale, 2020, 12,9647-9652
DOI: 10.1039/D0NR00416B, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Ewelina Wajs, Girish Rughoobur, Keith Burling, Anne George, Andrew J. Flewitt, Vincent J. Gnanapragasam
TFBAR technology demonstrates a cost-effective means for point-of-care diagnostics and monitoring of PSA.
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Mild generation of surface oxygen vacancy on CeO2 for improved CO2 photoreduction activity.

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR00717J, Paper
Min Wang, Meng Shen, Xixiong Jin, Jianjian Tian, Yajun Zhou, Yiran Shao, Lingxia Zhang, Yongsheng Li, Jianlin Shi
The vacancy defects of semiconductor photocatalysts play a key role in enhancing their photocatalytic CO2 reduction activity. In this work, CeO2 was chosen as a model catalyst and oxygen vacancy...
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Bad Neighbour, Good Neighbour: How Magnetic Dipole Interactions Between Soft and Hard Ferrimagnetic Nanoparticles Affect Macroscopic Magnetic Properties in Ferrofluids

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR02023K, Paper
Niéli Daffé, Jovana Zecevic, Kalliopi Trohidou, Marcin Sikora, Mauro Rovezzi, Claire Carvallo, Marianna Vasilakaki, Sophie Neveu, Johannes D. Meeldijk, Nadejda Bouldi, Veronica Gavrilov, Yohan Guyodo, Fadi Choueikani, Vincent Dupuis, Dario Taverna, Philippe Sainctavit, Amélie JUHIN
Fluids responding to magnetic fields (ferrofluids) offer a scene with no equivalent in nature to explore long-range magnetic dipole interactions. Here, we studied the very original class of binary ferrofluids,...
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Topological semimetal Li2CrN2 sheet as a promising hydrogen storage material

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR02180F, Paper
Lijuan Ma, Qiang Sun
An ideal electrode for electrochemical storage of hydrogen needs to be conductive for electron. The robust conductivity protected by topology in topological quantum materials just meets this requirement. However, such...
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How to handle rejection in your professional life

In this installment of Your Unicorn Career, our columnist writes about the power of persistence




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Cable-drawn ferry collides with 'progress'




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Hoover Dike protects 'Big Water' (Lake Okeechobee)




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'Hurricane-proof' inn success from the start




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Wacissa more promising than Tallahassee to Episcopaleans




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Dade Court House has 'escape proof' jail




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William C. Brooker, probate perfectionist




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Potential economic effects of the proposed Dominican Republic-Central America free trade agreement (DR-CAFTA) on the state of Florida




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The economic impact of the prosperity campaign on Hillsborough and Pinellas Counties




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The medical products industry cluster in Tampa Bay and Florida




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Potential economic effects of the proposed Free Trade Area of the Americas (FTAA) on the state of Florida




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The wage and productivity impacts of new jobs on the Hillsborough County economy




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The wage and productivity impacts of new jobs on the Hillsborough County economy




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The wage and productivity impacts of new jobs on the Hillsborough County economy




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Historical profile for the economy and demographics of Hardee County, 1990-2000




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Supplement to Historical profile for the economy and demographics of Hardee County, 1990-2000