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Calidore String Quartet




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Grammy-winning, genre-smashing quartet to visit Williamsport

Groundbreaking, Grammy-winning quartet Béla Fleck & The Flecktones is celebrating its 30th anniversary with an extended tour that will stop by the Community Arts Center on Tuesday, March 24, at 7:30 p.m.




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Quality Content in Demand as Multimedia Use Expands

Digital curricula repositories are helping to fill the growing need for more and better multimedia content.




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Quality Counts 2017: State Report Cards Map

This interactive map offers a quick way to examine state-by-state grades and summary data.




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Fin24.com | Indonesia was rocked by more than 11 000 earthquakes last year

Indonesia was rattled by more than 11 500 earthquakes last year, almost double the annual average of the past decade, according to the nation’s meteorological agency.




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Fin24.com | OPINION | Inequality, the part of the scary movie they don't show you

There’s always been massive inequality in South Africa, but those who have the money and power still aren’t getting it, says Carmen Williams.




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North Kivu: Into the Quagmire? An Overview of the Current Crisis in North Kivu




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Advanced quantification methods to improve the 18b dormancy model for assessing the activity of tuberculosis drugs in vitro. [Clinical Therapeutics]

One of the reasons for the lengthy tuberculosis (TB) treatment is the difficult to treat non-multiplying mycobacterial subpopulation. In order to assess the ability of (new) TB drugs to target this subpopulation, we need to incorporate dormancy models in our pre-clinical drug development pipeline. In most available dormancy models it takes a long time to create a dormant state and it is difficult to identify and quantify this non-multiplying condition.

The Mycobacterium tuberculosis 18b strain might overcome some of these problems, because it is dependent on streptomycin for growth and becomes non-multiplying after 10 days of streptomycin starvation, but still can be cultured on streptomycin-supplemented culture plates. We developed our 18b dormancy time-kill kinetic model to assess the difference in the activity of isoniazid, rifampicin, moxifloxacin and bedaquiline against log-phase growth compared to the non-multiplying M. tuberculosis subpopulation by CFU counting including a novel AUC-based approach as well as time-to-positivity (TTP) measurements.

We observed that isoniazid and moxifloxacin were relatively more potent against replicating bacteria, while rifampicin and high dose bedaquiline were equally effective against both subpopulations. Moreover, the TTP data suggest that including a liquid culture-based method could be of additional value as it identifies a specific mycobacterial subpopulation that is non-culturable on solid media.

In conclusion, the results of our study underline that the time-kill kinetics 18b dormancy model in its current form is a useful tool to assess TB drug potency and thus has its place in the TB drug development pipeline.




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Champions League Fantasy Matchday 7: The Scout squad

As the knockout stage kicks off this week, The Scout has put together a squad drawing on players from nine teams.




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Fin24.com | SA inequality grows as rich take larger share - report

New research has found that inequality in SA has increased, with wealth becoming ever more concentrated among the rich.




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Germany's Martinez equals UEFA finals scoring record

Germany's Shekiera Martinez, at 16, has written herself into UEFA's record books by scoring nine goals in a final tournament.




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Women's U17 EURO qualifying round report

The elite round line-up is set, with 26 teams earning spots alongside Germany and holders Spain in the 23 November draw.




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2019/20 #WU17EURO qualifying round draw

The 2019/20 qualifying round draw has been made, setting the first steps on the road to Sweden.




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Futsal EURO qualifying main round: full guide

Seven of the 12 places at UEFA Futsal EURO 2018 in Slovenia will be decided when the main round is played between Saturday and Tuesday, with Spain beginning their title defence.




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Spain, Italy, Russia among qualifiers as main round ends

Italy, Azerbaijan, Ukraine, Portugal, Spain, Kazakhstan and Russia joined hosts Slovenia in the finals by winning their main round groups while the eight play-off contenders are confirmed.




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Youth Olympics futsal qualifying report

The future of European futsal – male and female – was displayed over the last week in qualifying for the 2018 Youth Olympic games with Russia and Portugal coming out on top.




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Deals: Acer Computers, Blink XT2, 65-Inch Vizio P-Series Quantum X

Amazon is offering up to 30 percent off Acer laptops, desktops, and monitors. Plus, you can save $930 on the 65-inch Vizio P-Series Quantum X 4K TV.




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Back in the Sporting Day: 1970 Goodbye Lisbon Lions, hello Quality Street Gang

When Celtic arrived home after their defeat by Feyenoord on May 6, 1970, everyone at Parkhead was understandably deflated, while the fans were in mourning for the lost chance of glory.




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Coronavirus in Scotland: UK 'to bring in 14-day quarantine' for air passengers next month

People travelling to the UK will be quarantined for two weeks upon arrival as part of measures to prevent a second peak of the coronavirus pandemic.




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Collaborative Quality Improvement for Neonatal Intensive Care

Jeffrey D. Horbar
Jan 1, 2001; 107:14-22
ARTICLES




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2018/19 U19 EURO qualifying round draw made

The 2018/19 UEFA European Under-19 Championship qualifying round draw has been made in Nyon, starting the road to the July 2019 finals in Armenia.




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U19 EURO qualifying round report

The 13 qualifying round groups are complete, with 26 teams through to join top seeds Portugal and Germany in the elite round.




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U19 qualifying round latest

See who is through after October's mini-tournaments; the remaining groups run from 13 to 19 November.




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All October's qualifying results

Switzerland, England, Spain, Denmark, Germany, Netherlands and France extended their 100% starts.




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Crisis Group Congratulates the Tunisian National Dialogue Quartet

The International Crisis Group congratulates the members of the Tunisian National Dialogue Quartet as this year’s recipient of the Nobel Peace Prize. It is an apt recognition of its achievement in allowing the spirit of inclusion and compromise to triumph over the polarisation and violence that has been all too prevalent in the region, and of the central role civil society can play at moments of crisis.




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Champions League Fantasy Matchday 8: The Scout squad

Home advantage could be key with 13 of the 15 players in The Scout's squad playing second legs on their own ground.




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First Look: Apple's Pro Display XDR, Reference-Quality Imagery at a Palatable Price?

Apple's new $4,999 Pro Display XDR monitor (and its $1,000 stand) may sound mighty expensive on the surface. It has the potential to upend a whole industry, however—it's made to compete with panels five to ten times the price. We have one in-house, and here are our first impressions.




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Quarantine Rolls

Source: www.bitsandpieces.us - Friday, May 08, 2020
via




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Draws for the third qualifying round of UEFA Champions League and UEFA Europa League

041 - Draws to be held at UEFA headquarters in Nyon on 19 July




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Holyrood Committee launches inquiry into equality and human rights impact of Covid-19

The detrimental impact of Covid-19 and the lockdown measures imposed on people across Scotland is to be investigated by MSPs.




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Fin24.com | Unit trusts: the great equaliser

Unit trusts make investing possible for everyone.




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2018/19 U17 EURO qualifying round draw made

The road to the 16-team 2018/19 U17 EURO finals in the Republic of Ireland has begun with the qualifying round draw made, involving 52 of the hopefuls.




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U17 EURO qualifying round report

The 32 teams that will take part in March's elite round have been decided.




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2019/20 U17 qualifying round draw

The 2019/20 qualifying round draw has set the first steps on the road to Estonia.




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France's Aouchiche equals UEFA finals scoring record

France's Adil Aouchiche equalled a record shared by Michel Platini with his nine U17 EURO finals goals.




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Jimmy Kimmel’s Quarantine Monologue – Trump Won’t Wear Masks & Jane's Pancake Stand-off

Source: www.youtube.com - Wednesday, May 06, 2020




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2018/19 Women's U19 EURO qualifying round draw

The 2018/19 qualifying round draw has been made in Nyon involving 48 of the record entry of 51, with Liechtenstein making their debut in a women's football competition.




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Women's U19 EURO qualifying round report

The elite round line-up is complete with best third-placed teams Greece and Bulgaria joining the top two in each group.




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#UWCL qualifying round report

Breidablik, Mitrovica, Hibernian, Minsk, ŽFK Spartak, BIIK-Kazygurt, Braga, Anderlecht, Twente and Vllaznia made it through.




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Women's U19 qualifying round report

See which 28 teams are through to the elite round after the 11 qualifying round groups ended.




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Women's Champions League quarter-final line-up complete

Arsenal, Glasgow and Paris have joined Atlético, Barcelona, Bayern, holders Lyon and Wolfsburg in the last eight.




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Women's Champions League quarter-final guide

Holders Lyon face Bayern, Atlético take on Barcelona, Arsenal meet Paris and Glasgow play Wolfsburg.




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Women's EURO 2021 qualifying: how it stands

See how the groups are unfolding and how the 15 sides to join England in the finals will be decided.




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Google Claims Quantum Computing Achievement, IBM Says Not So Fast

Google's quantum computer performed a computation in 200 seconds that would have taken the world's fastest supercomputer 10,000 years to calculate. But IBM is dismissing Google's claim that it achieved quantum supremacy.




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Youth League quarter-final line-up complete

Real Madrid, Chelsea, Liverpool, Atlético Madrid, Tottenham and Porto won their round of 16 ties on Wednesday to join Barcelona and Manchester City in the quarter-finals.




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Youth League quarter-finals full of drama

Holders Barcelona, fellow two-time winners Chelsea, Porto and debutants Hoffenheim won their quarter-finals to reach Nyon.





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Wintrust Financial Corporation Reports Record Full-Year 2019 Net Income of $355.7 million and Fourth Quarter 2019 Net Income of $86.0 million, up 8% from the Fourth Quarter 2018

To view more press releases, please visit http://ir.wintrust.com/news.aspx?iid=1024452.




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Wintrust Financial Corporation Announces Cash Dividends, Increasing Quarterly Common Stock Dividend Rate 12%

To view more press releases, please visit http://ir.wintrust.com/news.aspx?iid=1024452.