In support of their AI ambitions, tech companies are rapidly expanding US data centres, and this growth is on track to significantly increase US gas demand by 2030

Soil is full of an uncountable number of viruses, and scientists are only beginning to understand just how substantial their role in the carbon cycle may be

A 2200-year-old burial ground in northern Italy includes people interred with dogs and horses, perhaps showing they had strong bonds with their animals

Isotopic analysis of horse teeth from a medieval burial site suggest that the animals were imported to England from Scandinavia or the Alps, perhaps for use in battle or jousting

Genetic analysis of 50,000-year-old Neanderthal skeletons has uncovered the remnants of three viruses related to modern human pathogens, and the researchers think they could be recreated

Title: Sunglasses Rival Lotions as Vital for Safety
Category: Health News
Created: 8/20/2010 12:10:00 PM
Last Editorial Review: 8/23/2010 12:00:00 AM

Title: U.S. Child Abuse Cases Falling, Despite Recession
Category: Health News
Created: 8/25/2010 12:10:00 PM
Last Editorial Review: 8/26/2010 12:00:00 AM

Title: CDC Revises Death Estimates From Flu
Category: Health News
Created: 8/26/2010 2:10:00 PM
Last Editorial Review: 8/27/2010 12:00:00 AM

Title: Missed Diagnoses in ICU Often Have Deadly Results: Review
Category: Health News
Created: 8/28/2012 2:05:00 PM
Last Editorial Review: 8/29/2012 12:00:00 AM

Title: West Nile Virus Cases Continue to Climb
Category: Health News
Created: 8/30/2012 11:00:00 AM
Last Editorial Review: 8/30/2012 12:00:00 AM

Title: New Clues to Causes of Autism Found
Category: Health News
Created: 8/29/2013 9:35:00 AM
Last Editorial Review: 8/29/2013 12:00:00 AM

Title: Mental and Substance Disorders Major Cause of Nonfatal Illnesses
Category: Health News
Created: 8/28/2013 7:35:00 PM
Last Editorial Review: 8/29/2013 12:00:00 AM

Title: Drinking Before First Pregnancy Raises Risk of Breast Cancer: Study
Category: Health News
Created: 8/28/2013 4:35:00 PM
Last Editorial Review: 8/29/2013 12:00:00 AM

Title: In Showdowns Between Sexes, Male Ego Bruises Easily
Category: Health News
Created: 8/30/2013 9:35:00 AM
Last Editorial Review: 8/30/2013 12:00:00 AM

Title: 2 Cases Suggest Stem Cell Transplant Might Ease 'Stiff Person' Syndrome
Category: Health News
Created: 8/26/2014 4:36:00 PM
Last Editorial Review: 8/27/2014 12:00:00 AM

Title: Electrical Pulses to Scalp May Boost Memory: Study
Category: Health News
Created: 8/28/2014 2:36:00 PM
Last Editorial Review: 8/29/2014 12:00:00 AM

Title: ADHD Risk Rises for Each Week a Preemie Is Born Early
Category: Health News
Created: 8/24/2015 12:00:00 AM
Last Editorial Review: 8/25/2015 12:00:00 AM

Title: Richer Houses Home to Wider Range of Bugs
Category: Health News
Created: 8/19/2016 12:00:00 AM
Last Editorial Review: 8/22/2016 12:00:00 AM

Title: Does Your Child Need Eyeglasses?
Category: Health News
Created: 8/19/2016 12:00:00 AM
Last Editorial Review: 8/22/2016 12:00:00 AM

Title: CDC Advises Pregnant Women to Avoid Miami Beach Due to Zika
Category: Health News
Created: 8/19/2016 12:00:00 AM
Last Editorial Review: 8/22/2016 12:00:00 AM

Title: Five Local Zika Cases Reported in Miami Beach
Category: Health News
Created: 8/19/2016 12:00:00 AM
Last Editorial Review: 8/22/2016 12:00:00 AM

Title: Five More Cases of Local Zika Infection Reported in Florida
Category: Health News
Created: 8/24/2016 12:00:00 AM
Last Editorial Review: 8/24/2016 12:00:00 AM

Title: Early Virus Raises Asthma Risk in Certain Kids: Study
Category: Health News
Created: 8/26/2016 12:00:00 AM
Last Editorial Review: 8/26/2016 12:00:00 AM

Title: Science Weighs in On How Fat Raises Cancer Risk
Category: Health News
Created: 9/1/2017 12:00:00 AM
Last Editorial Review: 9/1/2017 12:00:00 AM

Title: School Kids Need Supervision After Classes End
Category: Health News
Created: 8/26/2018 12:00:00 AM
Last Editorial Review: 8/27/2018 12:00:00 AM

Title: Low Back Pain? These Exercises May Help
Category: Health News
Created: 8/30/2018 12:00:00 AM
Last Editorial Review: 8/30/2018 12:00:00 AM

Title: Climate Change Raises Athletes' Risk of Heat Illness
Category: Health News
Created: 8/27/2019 12:00:00 AM
Last Editorial Review: 8/27/2019 12:00:00 AM

Title: AHA News: Study of Skiers Holds Surprises About A-Fib, Stroke and Intense Exercise
Category: Health News
Created: 8/26/2019 12:00:00 AM
Last Editorial Review: 8/27/2019 12:00:00 AM

Title: For Muslim Pilgrimage, Climate Change Poses Health Risks
Category: Health News
Created: 8/28/2019 12:00:00 AM
Last Editorial Review: 8/29/2019 12:00:00 AM

Title: Just Like COVID, Severe Flu Can Trigger Heart Crises
Category: Health News
Created: 8/25/2020 12:00:00 AM
Last Editorial Review: 8/25/2020 12:00:00 AM

Title: Thousands of COVID Cases Already on College Campuses
Category: Health News
Created: 8/26/2020 12:00:00 AM
Last Editorial Review: 8/26/2020 12:00:00 AM

Title: Maine Summer Camps Identified, Isolated COVID-19 Cases
Category: Health News
Created: 8/27/2020 12:00:00 AM
Last Editorial Review: 8/27/2020 12:00:00 AM

Title: President Trump Promises a COVID Vaccine Before the End of the Year
Category: Health News
Created: 8/28/2020 12:00:00 AM
Last Editorial Review: 8/28/2020 12:00:00 AM

Title: One Activity Causes 4 Out of 5 Sports-Linked Spinal Injuries
Category: Health News
Created: 8/25/2021 12:00:00 AM
Last Editorial Review: 8/25/2021 12:00:00 AM

Title: Recent COVID-19 Raises Odds for Clots After Surgery by 90%
Category: Health News
Created: 8/25/2021 12:00:00 AM
Last Editorial Review: 8/25/2021 12:00:00 AM

Title: Record High COVID Cases and Deaths Reported in Florida
Category: Health News
Created: 8/26/2021 12:00:00 AM
Last Editorial Review: 8/26/2021 12:00:00 AM

Title: COVID Vaccination Will Be Required on Disney Cruises to Bahamas
Category: Health News
Created: 8/26/2021 12:00:00 AM
Last Editorial Review: 8/26/2021 12:00:00 AM

Title: As Classes Resume, Some Health Tips From the CDC
Category: Health News
Created: 8/27/2021 12:00:00 AM
Last Editorial Review: 8/27/2021 12:00:00 AM

Title: Could Electrode 'Pulses' Cut Back, Leg Pain Without Drugs?
Category: Health News
Created: 8/26/2021 12:00:00 AM
Last Editorial Review: 8/27/2021 12:00:00 AM

Title: Cases of Advanced Cervical Cancer Keep Rising Among U.S. Women
Category: Health News
Created: 8/19/2022 12:00:00 AM
Last Editorial Review: 8/22/2022 12:00:00 AM

Title: What Causes Congestive Heart Failure?
Category: Diseases and Conditions
Created: 6/12/2020 12:00:00 AM
Last Editorial Review: 8/26/2022 12:00:00 AM

Title: Monkeypox Cases May Finally Be Ebbing, With Declines Seen in Europe, WHO Says
Category: Health News
Created: 8/25/2022 12:00:00 AM
Last Editorial Review: 8/25/2022 12:00:00 AM

Title: What Causes Henipavirus?
Category: Diseases and Conditions
Created: 8/26/2022 12:00:00 AM
Last Editorial Review: 8/26/2022 12:00:00 AM

Title: As Pandemic Eases, It's Boom Times for Cosmetic Surgeons
Category: Health News
Created: 8/24/2022 12:00:00 AM
Last Editorial Review: 8/24/2022 12:00:00 AM

Title: What Causes Lower Abdominal Pain in Men?
Category: Diseases and Conditions
Created: 7/15/2022 12:00:00 AM
Last Editorial Review: 7/15/2022 12:00:00 AM

Title: Bedsores Can Cause Serious Harm — Are U.S. Nursing Homes Hiding Cases?
Category: Health News
Created: 8/17/2022 12:00:00 AM
Last Editorial Review: 8/18/2022 12:00:00 AM

Title: Salicylate Sensitivity Causes, Symptoms, and Foods to Avoid
Category: Health and Living
Created: 7/8/2022 12:00:00 AM
Last Editorial Review: 7/8/2022 12:00:00 AM

Retrotransposable elements (RTEs) are common mobile genetic elements comprising ~42% of the human genome. RTEs play critical roles in gene regulation and function, but how they are specifically involved in complex diseases is largely unknown. Here, we investigate the cellular heterogeneity of RTEs using 12 single-cell transcriptome profiles covering three neurodegenerative diseases, Alzheimer's disease (AD), Parkinson's disease, and multiple sclerosis. We identify cell type marker RTEs in neurons, astrocytes, oligodendrocytes, and oligodendrocyte precursor cells that are related to these diseases. The differential expression analysis reveals the landscape of dysregulated RTE expression, especially L1s, in excitatory neurons of multiple neurodegenerative diseases. Machine learning algorithms for predicting cell disease stage using a combination of RTE and gene expression features suggests dynamic regulation of RTEs in AD. Furthermore, we construct a single-cell atlas of retrotransposable elements in neurodegenerative disease (scARE) using these data sets and features. scARE has six feature analysis modules to explore RTE dynamics in a user-defined condition. To our knowledge, scARE represents the first systematic investigation of RTE dynamics at the single-cell level within the context of neurodegenerative diseases.

PWAS (proteome-wide association study) is an innovative genetic association approach that complements widely used methods like GWAS (genome-wide association study). The PWAS approach involves consecutive phases. Initially, machine learning modeling and probabilistic considerations quantify the impact of genetic variants on protein-coding genes’ biochemical functions. Secondly, for each individual, aggregating the variants per gene determines a gene-damaging score. Finally, standard statistical tests are activated in the case-control setting to yield statistically significant genes per phenotype. The PWAS Hub offers a user-friendly interface for an in-depth exploration of gene–disease associations from the UK Biobank (UKB). Results from PWAS cover 99 common diseases and conditions, each with over 10,000 diagnosed individuals per phenotype. Users can explore genes associated with these diseases, with separate analyses conducted for males and females. For each phenotype, the analyses account for sex-based genetic effects, inheritance modes (dominant and recessive), and the pleiotropic nature of associated genes. The PWAS Hub showcases its usefulness for asthma by navigating through proteomic-genetic analyses. Inspecting PWAS asthma-listed genes (a total of 27) provide insights into the underlying cellular and molecular mechanisms. Comparison of PWAS-statistically significant genes for common diseases to the Open Targets benchmark shows partial but significant overlap in gene associations for most phenotypes. Graphical tools facilitate comparing genetic effects between PWAS and coding GWAS results, aiding in understanding the sex-specific genetic impact on common diseases. This adaptable platform is attractive to clinicians, researchers, and individuals interested in delving into gene–disease associations and sex-specific genetic effects.

Sequence variation observed in populations of pathogens can be used for important public health and evolutionary genomic analyses, especially outbreak analysis and transmission reconstruction. Identifying this variation is typically achieved by aligning sequence reads to a reference genome, but this approach is susceptible to reference biases and requires careful filtering of called genotypes. There is a need for tools that can process this growing volume of bacterial genome data, providing rapid results, but that remain simple so they can be used without highly trained bioinformaticians, expensive data analysis, and long-term storage and processing of large files. Here we describe split k-mer analysis (SKA2), a method that supports both reference-free and reference-based mapping to quickly and accurately genotype populations of bacteria using sequencing reads or genome assemblies. SKA2 is highly accurate for closely related samples, and in outbreak simulations, we show superior variant recall compared with reference-based methods, with no false positives. SKA2 can also accurately map variants to a reference and be used with recombination detection methods to rapidly reconstruct vertical evolutionary history. SKA2 is many times faster than comparable methods and can be used to add new genomes to an existing call set, allowing sequential use without the need to reanalyze entire collections. With an inherent absence of reference bias, high accuracy, and a robust implementation, SKA2 has the potential to become the tool of choice for genotyping bacteria. SKA2 is implemented in Rust and is freely available as open-source software.