Since lung cancer (LC) is still the leading cause of cancer deaths worldwide [1], early detection through screening represents an important opportunity to improve LC survival and is a priority area for cancer care. The National Lung Screening Trial (NLST) aimed to compare low-dose helical computed tomography (LDCT) with chest radiography in LC screening of current or former heavy smokers. The trial found a relative reduction in mortality from LC of 20% in those who had undergone LDCT screening. LC screening has regained prominence in the thoracic oncology literature with the completion of NELSON and other European trials, which support the role of LC screening in achieving early diagnosis and reducing mortality. A growing number of implementation pilots are providing an impetus towards organised, national programmes for LC screening, which are in need of long-term follow-up data such as those presented in this study.

A 78-year-old male presented at the emergency room complaining of dry cough, fever up to 38.5 °C and malaise for 1 month. He had visited a general practitioner and received amoxicillin 500 mg three times a day for 7 days for a presumed chest infection, without improvement. He had a history of diabetes and arterial blood hypertension, for which he was receiving metformin 1000 mg twice a day and amlodipine 10 mg a day for 7 years. He reported no alcohol abuse and was an ex-smoker of 20 pack-years (quit 30 years ago). He had no recent hospitalisations or any medical interventions.

Bearing in mind that maintaining a united front against the virus can bode well for the country.

Congratulations to first-time mother Echo the cheetah!

The war veteran has raised more than £30million so far

The nation is preparing to celebrate the 75th anniversary of Victory in Europe (VE) Day , with the Queen set to make a historic address to mark the occasion.

The Nation

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Lockdown life is raising new challenges for all of us, but the experience may help people empathise with single parents more, writes single mother and The Mother Edit blogger, Rebecca Cox

Plus tips from a National Trust gardener on how to grow your own at home

A group of cyber sleuths from Adelaide takes out the national missing persons "hackathon", finding nearly 100 new pieces of information for police to investigate.

Donald Trump has in recent days turned the war against COVID-19 into a war against the states, in a desperate effort to shirk responsibility for his pandemic denialism.

We appreciate the diligent work of the National Research Council’s committee on forensic science in preparing this report. The Department of Justice’s principal focus in dealing with forensic evidence is on applying it dispassionately to law enforcement challenges, and we regularly use forensics to not only convict the guilty, but also to exonerate the innocent.

"Tonight we hold a vigil, but every day we must be vigilant. So let us bind ourselves together with a new bond of service -- to make our country brighter, safer and more hopeful -- and in so doing, let us honor the memory of our fallen heroes every day."

"Let us bind ourselves together in a new bond of service -- to make our country brighter, safer, and more hopeful -- and in so doing, let us bear true witness to the legacies of our fallen heroes."

"Preventing the sexual exploitation of children, and stopping and punishing those who do it are a leading priority. The Department aggressively enforces the laws at our disposal to protect our children."

"By focusing on increased cooperation between the U.S. and Mexican governments as well as enhanced communication within U.S. law enforcement agencies, the National Southwest Border Counternarcotics Strategy we introduce today provides an effective way forward that will crack down on cartels and make our country safer."

"You at NIJ are not only the scientists, you are also the builders. As you design and test your theories, you construct a foundation on which together we will build strong, credible policies. I thank you for your commitment to science and to improving the world in which we live. What you do is important to every citizen in this country."

Deputy Attorney General David W. Ogden today announced plans by the Department of Justice to significantly expand its training and education operations at the National Advocacy Center (NAC), the core training facility for local, state and federal attorneys, law enforcement agents and support personnel.

"As a prosecutor, you need to be determined enough to pursue every single violent criminal, no matter how cold the evidence. You need to be dogged enough to charge all meritorious cases, no matter how difficult the challenges. You need to be tough enough to withstand public scrutiny, no matter how unfair the criticism."

"People who actually work in law enforcement, and people who actually work in our nation’s schools, know that our jobs are closely interwoven. When their neighborhoods and homes don’t feel safe, our children have a tough time paying attention in school. And when our children are not engaged at school, they’re going to be much more likely to get into trouble outside of it."

Sexual violence is not just an issue for the victim, or his or her family. We believe the community must be involved in addressing the needs of survivors and holding offenders accountable.

"Today’s summit marks a critical step forward in the work being done by HEAT, our Health Care Fraud Prevention and Enforcement Action Team," said Attorney General Holder.

"These days of reflection are an important opportunity for us to come together in support of victims, to give voice to their suffering and to light the way toward a hopeful future," said Attorney General Holder.

"Today, we’ve come together, from as far as Omaha and Albuquerque, Portland and Philadelphia, to recognize men and women who have found their calling in the service of others," said Attorney General Holder.

"For today’s Justice Department, our work to pursue human trafficking investigations and prosecutions and to support those who serve and assist victims is not simply a top priority. It’s also a source of great pride," said Attorney General Holder.

As you know better than anyone else, our Internet Crimes Against Children Task Forces, are truly the front line fighters in the battle against child exploitation.

"Every year, hundreds of billions of dollars are spent to provide health care for millions of American seniors, children and the disabled," said Acting Deputy Attorney General Gary G. Grindler.

"Tonight is testament to the indispensable role the Memorial Fund plays in honoring the service and sacrifice of our nation’s men and women in uniform – not only at this annual vigil but every day of the year," said Attorney General Holder.

"The Justice Department is proud to count the National Center as a partner. And, today, I’m pleased to announce an award to the National Center of more than $30 million to support and continue its critical work," said Attorney General Holder.

"For nearly two decades, NADCP’s leadership and membership have served as extraordinary partners to government in the administration of justice," said Attorney General Holder.

"The progress made in 20 years is remarkable. But our anniversary celebration must be marked by turning our attention to the next 20 years so that we can continue to create a nation where every individual has access to equal opportunity and equal justice," said Assistant Attorney General Thomas E. Perez

"It’s my understanding that strengthening federal and state partnerships was one of the founding principles of this Association, and I hope to summon this afternoon the same spirit of shared aspiration, joint responsibility and, above all, strong partnership, that this association has been cultivating for more than a century," said Acting Deputy Attorney General Grindler.

"As the Justice Department brings its fight against child exploitation to a new level today, I am honored to stand with so many incredible colleagues and public servants who have made it their life’s work to protect exploited children and seek justice for the most vulnerable members of our society," said Acting Deputy Attorney General Grindler.

"Today marks an important step forward in meeting these responsibilities and taking our fight against child exploitation and sexual abuse to the next level," said Attorney General Holder.

"Today, as we read the names of these fallen heroes, we also reflect on their lives, their legacies, their courage, and their special calling – a calling to serve others; a calling that’s shared by every member of our nation’s law enforcement community; and a calling that’s firmly founded on the principles of self-sacrifice and personal bravery which were so vividly exemplified by each of these men and women whom we honor here this morning," said Attorney General Holder.

"I am proud to be a part of this celebration. And I am honored to gather with so many partners, public servants, and distinguished guests as we break ground on a center that will become a place of learning and healing, of reflection and inspiration."

"I am deeply honored by your invitation to be with you today and to share with you some of the work in which we have been engaged at the Department of Justice to improve life in Indian Country," said Assistant Attorney General West.

"As our nation’s Attorney General, and as a parent of two teenage daughters, addressing violence rates – and implementing bold, innovative and collaborative solutions – is a top priority."

"The importance of this process can not be overstated – our system of government relies upon giving everyone an equal voice – and the decennial redistricting process ensures integrity in our system."

"I believe that this is a time of extraordinary opportunity – the opportunity to be more creative and innovative; to transform systems in need of reform; to harness 21st-century technologies; to incorporate research and science into our decision-making processes; to break down long-standing barriers to communication and cost-sharing; to forge and strengthen partnerships across, and beyond, government; and, even as we’re called on to do more with less, to do better for the most vulnerable citizens we serve."

"President Obama and Attorney General Holder recognize that civil rights enforcement is about protecting individual rights and helping entire communities," said Assistant Attorney General Perez.

"Each of you has been invited because of your experience, your expertise, and your influence within your constituencies. What we have in this room today is a gathering of many of the most influential criminal justice stakeholders in the nation and we’re going to really try to leverage that influence."

"I know that you are dedicated to your clients, and to defending them as vigorously as you can, while at the same time recognizing the importance of criminal prosecution to society. And in representing clients who would not have the means to defend themselves without you, you are essential to our adversary system."

"As we rededicate ourselves to this work, I can’t help but feel optimistic about where we’ll arrive – and what we will achieve – together. Not only do I look forward to hearing about the discussions that you will have – and the recommendations that you will develop – during this symposium, I look forward to our continued partnership, our continued progress, and our continued pursuit of security, opportunity, and justice for all."

"This evidence-based approach to public safety issues is important across the criminal justice spectrum. I’ve made it a top priority at OJP. Shortly after taking office in 2009, I launched my Evidence Integration Initiative – we call it E2I, for short. Our goal is to both improve the quantity and quality of research and other evidence that we generate and get that information out to the field in a useable format."

"As we have seen repeatedly – most clearly on September 11th and in the aftermath of Hurricane Katrina – in times of crisis and emergency, law enforcement officers and first responders must be able to communicate quickly, across all jurisdictions. And as national security and public safety threats have continued to grow and to evolve, the need to bring public safety communications into the 21st century has never been greater."

"I know with all of us working together to shape our future – thinking together in new ways and re-imagining our potential – the victim service field will be stronger, more effective, and better able to ensure a safer and more just world."

The complaint, filed today in the U.S. District Court for the Middle District of Louisiana, alleges that Louisiana has violated the NVRA by failing to provide voter registration services at offices providing public assistance and serving persons with disabilities in Louisiana.

"As prosecutors, we occupy a unique role in the criminal justice system. Our job is not just to win cases, but also to do justice in every case."