paper to write a nutrition case study paper By english.al-akhbar.com Published On :: to write a nutrition case study paper Full Article
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paper Update of the Readiness Assessment for Cross-Border Paperless Trade: Bangladesh By www.adb.org Published On :: 2024-11-08 This report highlights Bangladesh’s cross-border paperless trade readiness, outlines the significant legal and technical gaps it still needs to address, and provides a comprehensive action plan. Full Article
paper Physicists determined the paper most likely to give you a paper cut By www.newscientist.com Published On :: Fri, 28 Jun 2024 13:00:04 +0100 An experiment with a robot and gelatine determined that 65-micrometre-thick paper is the most prone to slicing our skin – but it can also make for a handy recyclable knife Full Article
paper NEAT1 promotes genome stability via m6A methylation-dependent regulation of CHD4 [Research Papers] By genesdev.cshlp.org Published On :: 2024-10-16T07:18:56-07:00 Long noncoding (lnc)RNAs emerge as regulators of genome stability. The nuclear-enriched abundant transcript 1 (NEAT1) is overexpressed in many tumors and is responsive to genotoxic stress. However, the mechanism that links NEAT1 to DNA damage response (DDR) is unclear. Here, we investigate the expression, modification, localization, and structure of NEAT1 in response to DNA double-strand breaks (DSBs). DNA damage increases the levels and N6-methyladenosine (m6A) marks on NEAT1, which promotes alterations in NEAT1 structure, accumulation of hypermethylated NEAT1 at promoter-associated DSBs, and DSB signaling. The depletion of NEAT1 impairs DSB focus formation and elevates DNA damage. The genome-protective role of NEAT1 is mediated by the RNA methyltransferase 3 (METTL3) and involves the release of the chromodomain helicase DNA binding protein 4 (CHD4) from NEAT1 to fine-tune histone acetylation at DSBs. Our data suggest a direct role for NEAT1 in DDR. Full Article
paper YY1 knockout in pro-B cells impairs lineage commitment, enabling unusual hematopoietic lineage plasticity [Research Papers] By genesdev.cshlp.org Published On :: 2024-10-16T07:18:56-07:00 During B-cell development, cells progress through multiple developmental stages, with the pro-B-cell stage defining commitment to the B-cell lineage. YY1 is a ubiquitous transcription factor that is capable of both activation and repression functions. We found here that knockout of YY1 at the pro-B-cell stage eliminates B lineage commitment. YY1 knockout pro-B cells can generate T lineage cells in vitro using the OP9-DL4 feeder system and in vivo after injection into sublethally irradiated Rag1–/– mice. These T lineage-like cells lose their B lineage transcript profile and gain a T-cell lineage profile. Single-cell RNA-seq experiments showed that as YY1 knockout pro-B cells transition into T lineage cells in vitro, various cell clusters adopt transcript profiles representing a multiplicity of hematopoietic lineages, indicating unusual lineage plasticity. In addition, YY1 KO pro-B cells in vivo can give rise to other hematopoietic lineages in vivo. Evaluation of RNA-seq, scRNA-seq, ChIP-seq, and scATAC-seq data indicates that YY1 controls numerous chromatin-modifying proteins leading to increased accessibility of alternative lineage genes in YY1 knockout pro-B cells. Given the ubiquitous nature of YY1 and its dual activation and repression functions, YY1 may regulate commitment in multiple cell lineages. Full Article
paper A germline PAF1 paralog complex ensures cell type-specific gene expression [Research Papers] By genesdev.cshlp.org Published On :: 2024-10-16T07:18:56-07:00 Animal germline development and fertility rely on paralogs of general transcription factors that recruit RNA polymerase II to ensure cell type-specific gene expression. It remains unclear whether gene expression processes downstream from such paralog-based transcription is distinct from that of canonical RNA polymerase II genes. In Drosophila, the testis-specific TBP-associated factors (tTAFs) activate over a thousand spermatocyte-specific gene promoters to enable meiosis and germ cell differentiation. Here, we show that efficient termination of tTAF-activated transcription relies on testis-specific paralogs of canonical polymerase-associated factor 1 complex (PAF1C) proteins, which form a testis-specific PAF1C (tPAF). Consequently, tPAF mutants show aberrant expression of hundreds of downstream genes due to read-in transcription. Furthermore, tPAF facilitates expression of Y-linked male fertility factor genes and thus serves to maintain spermatocyte-specific gene expression. Consistently, tPAF is required for the segregation of meiotic chromosomes and male fertility. Supported by comparative in vivo protein interaction assays, we provide a mechanistic model for the functional divergence of tPAF and the PAF1C and identify transcription termination as a developmentally regulated process required for germline-specific gene expression. Full Article
paper Dysregulating mTORC1-4E-BP2 signaling in GABAergic interneurons impairs hippocampus-dependent learning and memory [RESEARCH PAPERS] By learnmem.cshlp.org Published On :: 2024-10-28T08:52:55-07:00 Memory formation is contingent on molecular and structural changes in neurons in response to learning stimuli—a process known as neuronal plasticity. The initiation step of mRNA translation is a gatekeeper of long-term memory by controlling the production of plasticity-related proteins in the brain. The mechanistic target of rapamycin complex 1 (mTORC1) controls mRNA translation, mainly through phosphorylation of the eukaryotic initiation factor 4E (eIF4E)-binding proteins (4E-BPs) and ribosomal protein S6 kinases (S6Ks). mTORC1 signaling decreases throughout brain development, starting from the early postnatal period. Here, we discovered that in mice, the age-dependent decrease in mTORC1 signaling occurs selectively in excitatory but not inhibitory neurons. Using a gene conditional knockout (cKO) strategy, we demonstrate that either up- or downregulating the mTORC1-4E-BP2 axis in GAD65 inhibitory interneurons, but not excitatory neurons, results in long-term object recognition and object location memory deficits. Our data indicate that the mTORC1 pathway in inhibitory but not excitatory neurons plays a key role in memory formation. Full Article
paper The influence of categorical stimuli on relational memory binding [RESEARCH PAPERS] By learnmem.cshlp.org Published On :: 2024-10-31T09:40:31-07:00 Binding of arbitrary information into distinct memory representations that can be used to guide behavior is a hallmark of relational memory. What is and is not bound into a memory representation and how those things influence the organization of that representation remain topics of interest. While some information is intentionally and effortfully bound—often the information that is consistent with task goals or expectations about what information may be required later—other information appears to be bound automatically. The present set of experiments sought to investigate whether spatial memory would be systematically influenced by the presence and absence of distinct categories of stimuli on a spatial reconstruction task. In this task, participants must learn multiple item-location bindings and place each item back in its studied location after a short delay. Across three experiments, participants made significantly more within-category errors (i.e., misassigning one item to the location of a different item from the same category) than between-category errors (i.e., misassigning one item to the location of an item from a different category) when categories were perceptually or semantically distinct. These data reveal that category information contributed to the organization of the memory representation and influenced spatial reconstruction performance. Together, these results suggest that categorical information can influence memory organization, and not always to the benefit of overall task performance. Full Article
paper RPG Cast – Episode 697: “Paper Marliano” By rpgamer.com Published On :: Sat, 28 Oct 2023 19:27:40 +0000 Chris builds a house with a tiger in it. Ryan remembers that bush. And Robert has to fend off the fan boys trying to take his Nikke girls. One week till Extra Life, please help us heal kids and identify bicycles. The post RPG Cast – Episode 697: “Paper Marliano” appeared first on RPGamer. Full Article News Podcasts RPG Cast Final Fantasy V Mary Skelter 2 Path of Exile Silent Hope
paper The Sunday Papers By www.rockpapershotgun.com Published On :: Sun, 03 Nov 2024 11:00:00 +0000 It's official: I am once again the Sunday correspondent around here. That means it falls to me to round up (mostly) good (mostly) writing about (mostly) video games. I will otherwise be spending my Sunday continuing the fight against my dog's fleas, which rebound every three weeks no matter how much I spray, scrub or throw things away. On, the independent video game magazine which I linked to last week, has run a series of brief interviews with each of the contributors to its launch issue. I recommend Christian Donlan's for the puzzle game recommendations and Margaret Robertson's which expands on her fascination with Japanese paper games. Read more Full Article The Sunday Papers Blockbuster
paper The Sunday Papers By www.rockpapershotgun.com Published On :: Sun, 10 Nov 2024 11:00:00 +0000 November 8th, 2005 was my first day as a full-time games journalist, which means I have now entered my 20th year of doing this. "This" has changed a lot over time: from producing CD and DVD coverdiscs, to writing for a magazine, to editing magazines and a website, to solely editing a website, to managing several websites. Sprinkle podcasts, videos, events and a lot of other things in there and "games journalist" doesn't really cover it. One of the only constants is that I read a lot of writing about video games. Dapper gent Oli Welsh wrote for Polygon about the fan reboot of City Of Heroes. We briefly covered fans getting an official license earlier this year, but Oli went and spoke to the folks making it all work. Read more Full Article The Sunday Papers Blockbuster
paper TekniPlex Healthcare to debut strong paper for medical packaging at Pack Expo By www.medicalplasticsnews.com Published On :: Fri, 01 Nov 2024 10:00:00 -0000 TekniPlex Healthcare is set to unveil its strongest-ever reinforced paper for medical device packaging applications at Pack Expo 2024, 3-6 November in Chicago. Full Article
paper Last Call for SAS Global Forum Papers By www.sas.com Published On :: 2016-09-29T12:00:00Z You have just a few more days to submit your paper proposal for the 2017 SAS® Global Forum in Orlando on April 2–5. The call for papers ends and registration begins October 3. Full Article
paper Mock Test Papers Series I and II for CA Final Students Appearing in Nov 2024 Exams By www.caclubindia.com Published On :: Thu, 5 Sep 2024 09:08:57 GMT Mock Test Papers Series I & II for CA Final Students Appearing in Nov 2024 Exams Full Article
paper CA Intermediate Advanced Accounting Question Paper New Course September 2024 By www.caclubindia.com Published On :: Sat, 14 Sep 2024 10:44:39 GMT Download CA Intermediate Advanced Accounting Question Papers New Course Sep 2024 in PDF. For other question papers of CA IPC May 2024, Nov 2023, May 2023, Nov 2022, May 2022, Dec 2021, Nov 2020, Nov 18, May 18, Nov 2017, May 2017, May 2016, CA IPC Nov 2015, CA IPC may 2015, CA IPC Nov 2014 check similar section. Previous years Advanced Accounting CA Intermediate IPC question papers can also be downloaded using Search. You can also search and download may 2015 Final question papers here. We are providing ca final question papers of may 2016 for Financial Reporting FR, Advanced Financial Management AFM, Advanced Auditing and Professional Ethics, Direct Tax Laws DT, Indirect Tax Laws IDT and Inter/IPC May 2024 question papers for Advanced Accounting, Corporate and Other Laws, Taxation, Advanced Accounting , Auditing & Assurance, Information Technology & Strategic Management ITSM. Full Article
paper CA Intermediate Corporate and Other Laws Question Paper New Course September 2024 By www.caclubindia.com Published On :: Tue, 17 Sep 2024 17:16:02 GMT Download CA Inter Corporate and Other Laws New Course Question Papers Sep 2024 in PDF. For other question papers of CA IPC May 2023, Nov 2023, May 2023, Nov 2022, May 2022, Dec 2021, July 2021, Nov 2020, Nov 2019, May 2019, Nov 18, May 18, Nov 2017, May 17, Nov 2016, may 2016, CA IPC Nov 2015, CA IPC may 2015, CA IPC Nov 2014 check similar section. Previous years business law, Ethics and Communication CA Inter IPC question papers can also be downloaded using Search. You can also search and download may 2015 Final question papers here. We are providing ca final question papers of may 2016 for Financial Reporting FR, Advanced Financial Management AFM, Advanced Auditing and Professional Ethics, Corporate & Allied business laws, Advanced & Management Accounting AMA, Information Systems Control & Audit ISCA, Direct Tax business laws DT, Indirect Tax business laws IDT and Inter/IPC may 2015 question papers for Advanced Accounting, Taxation, Advanced Accounting , Auditing & Assurance, Information Technology & Strategic Management ITSM Full Article
paper CA Intermediate Taxation Question Paper New Course September 2024 By www.caclubindia.com Published On :: Thu, 19 Sep 2024 16:21:20 GMT Download CA Intermediate Taxation Question Papers New Course Sep 2024 in PDF. For other question papers of CA Inter May 2024, Nov 2023, May 2023, Nov 2022, May 2022, Dec 2021, July 2021, Nov 2020, Nov 2019, May 2019, Nov 18, May 2018, Nov 2017, Nov 2016, May 2016, May 17, may 2016, CA IPC Nov 2015, CA IPC may 2015, CA IPC Nov 2014 check similar section. Previous years Taxation CA IPCC IPC question papers can also be downloaded using Search. You can also search and download may 2015 Final question papers here. We are providing ca final question papers of may 2016 for Financial Reporting FR, Advanced Financial Management AFM, Advanced Auditing and Professional Ethics, Taxation, Corporate & Allied Laws,Advanced & Management Accounting AMA, Direct Tax Laws DT, Indirect Tax Laws IDT and IPCC/IPC may 2015 question papers for Advanced Accounting , Business, Law, Ethics & Communications, Taxation, Advanced Accounting , Auditing & Assurance, Information Technology & Strategic Management ITSM. Full Article
paper CA Intermediate Cost and Management Accounting Question Paper New Course September 2024 By www.caclubindia.com Published On :: Fri, 20 Sep 2024 17:09:45 GMT Download CA Intermediate Cost and Management Accounting Question Papers New Course Sep 2024 in PDF. For other question papers of CA Inter May 2024, Nov 2023, May 2023, Nov 2022, May 2022, Dec 2021, July 2021, Nov 2020, Nov 2019, May 2019, Nov 18, May 2018, Nov 2017, Nov 2016, May 2016, May 17, may 2016, CA IPC Nov 2015, CA IPC may 2015, CA IPC Nov 2014 check similar section. Previous years Taxation CA IPCC IPC question papers can also be downloaded using Search. You can also search and download may 2015 Final question papers here. We are providing ca final question papers of may 2016 for Financial Reporting FR, Advanced Financial Management AFM, Advanced Auditing and Professional Ethics, Taxation, Corporate & Allied Laws,Advanced & Management Accounting AMA, Direct Tax Laws DT, Indirect Tax Laws IDT and IPCC/IPC may 2015 question papers for Advanced Accounting , Business, Law, Ethics & Communications, Taxation, Advanced Accounting , Auditing & Assurance, Information Technology & Strategic Management ITSM. Full Article
paper CA Intermediate Auditing and Ethics Question Paper New Course September 2024 By www.caclubindia.com Published On :: Tue, 24 Sep 2024 12:37:29 GMT Download CA Intermediate Auditing and Ethics Question Papers New Course Sep 2024 in PDF. For other question papers of CA IPC May 2024, Nov 2023, May 2023, Nov 2022, May 2022, Dec 2021, Nov 2020, Nov 18, May 18, Nov 2017, May 2017, May 2016, CA IPC Nov 2015, CA IPC may 2015, CA IPC Nov 2014 check similar section. Previous years Auditing and Ethics CA Intermediate IPC question papers can also be downloaded using Search. You can also search and download may 2015 Final question papers here. We are providing ca final question papers of may 2016 for Financial Reporting FR, Advanced Financial Management AFM, Advanced Auditing and Professional Ethics, Direct Tax Laws DT, Indirect Tax Laws IDT and Inter/IPC May 2024 question papers for Advanced Accounting, Corporate and Other Laws, Taxation, Advanced Accounting , Auditing & Assurance, Information Technology & Strategic Management ITSM. Full Article
paper CA Intermediate Financial Management and Strategic Management Question Paper New Course September 2024 By www.caclubindia.com Published On :: Wed, 25 Sep 2024 17:02:36 GMT Download CA Intermediate Financial Management and Strategic Management Question Papers New Course Sep 2024 in PDF. For other question papers of CA Inter May 2024, Nov 2023, May 2023, Nov 2022, May 2022, Dec 2021, July 2021, Nov 2020, Nov 2019, May 2019, Nov 18, May 2018, Nov 2017, Nov 2016, May 2016, May 17, may 2016, CA IPC Nov 2015, CA IPC may 2015, CA IPC Nov 2014 check similar section. Previous years Taxation CA IPCC IPC question papers can also be downloaded using Search. You can also search and download may 2015 Final question papers here. We are providing ca final question papers of may 2016 for Financial Reporting FR, Advanced Financial Management AFM, Advanced Auditing and Professional Ethics, Taxation, Corporate & Allied Laws,Advanced & Management Accounting AMA, Direct Tax Laws DT, Indirect Tax Laws IDT and IPCC/IPC may 2015 question papers for Advanced Accounting , Business, Law, Ethics & Communications, Taxation, Advanced Accounting , Auditing & Assurance, Information Technology & Strategic Management ITSM. Full Article
paper CA Final Advanced Financial Management (AFM) Paper New Course Nov 2024 By www.caclubindia.com Published On :: Wed, 6 Nov 2024 12:07:08 GMT Download CA Final Advanced Financial Management (AFM) Question Papers New Course Nov 2024 in PDF. For older question papers of CA final May 2024, Nov 2023, May 2023, Nov 2022, May 2022, Dec 2021, Nov 2020, May 2019, Nov 2018,CA final May 2018, Nov 2017, May 2017, CA final may 2016, CA final Nov 2016 check similar section. Previous years CA final Financial Reporting FR question papers can also be downloaded using Search. You can also search and download may 2015 IPCC & IPC question papers here. We are providing ca final question papers of may 2016 for Financial Reporting FR, Advanced Financial Management AFM, Advanced Auditing and Professional Ethics, Direct Tax Laws DT, Indirect Tax Laws IDT,Integrated Business Solutions (Multidisciplinary Case Study with Strategic Management) and IPCC/IPC Nov 2023 question papers for Accounting, Business, Law, Ethics & Communications , Cost Accounting & Financial Management CAFM, Taxation, Advanced Accounting , Auditing & Assurance, Information Technology & Strategic Management ITSM. Full Article
paper CA Final Financial Reporting (FR) Paper New Course Nov 2024 By www.caclubindia.com Published On :: Wed, 6 Nov 2024 12:07:24 GMT Download CA Final Financial Reporting FR Question Papers New Course Nov 2024 in PDF. For older question papers of CA final May 2024, Nov 2023, May 2023, Nov 2022, May 2022, Dec 2021, Nov 2020, May 2019, Nov 2018,CA final May 2018, Nov 2017, May 2017, CA final may 2016, CA final Nov 2016 check similar section. Previous years CA final Financial Reporting FR question papers can also be downloaded using Search. You can also search and download may 2015 IPCC & IPC question papers here. We are providing ca final question papers of may 2016 for Financial Reporting FR, Advanced Financial Management AFM, Advanced Auditing, Assurance And Professional Ethics, Direct Tax Laws DT, Indirect Tax Laws IDT, Integrated Business Solutions (Multidisciplinary Case Study with Strategic Management) and IPCC/IPC Nov 2023 question papers for Accounting , Business, Law, Ethics & Communications , Cost Accounting & Financial Management CAFM, Taxation, Advanced Accounting , Auditing & Assurance, Information Technology & Strategic Management ITSM. Full Article
paper CA Final Advanced Auditing, Assurance And Professional Ethics Question Paper New Course Nov 2024 By www.caclubindia.com Published On :: Fri, 8 Nov 2024 15:02:17 GMT Download CA Final Advanced Auditing, Assurance And Professional Ethics Question Papers Nov 2024 in PDF. For older question papers of CA final May 2024, Nov 2024, May 2023, Nov 2022, May 2022, Dec 2021, July 2021, Jan 2021, Dec 2020, Nov 2020, Nov 19, May 2019, Nov 2018, May 18, Nov 2017, May 2017, May 16, Nov 2015, CA final may 2014, CA final Nov 2014 check similar section. Previous years CA final Advanced Auditing and Professional Ethics question papers can also be downloaded using Search. You can also search and download may 2015 IPCC & IPC question papers here. We are providing ca final question papers of may 2016 for Financial Reporting FR, Advanced Financial Management AFM, Advanced Auditing, Assurance And Professional Ethics, Direct Tax Laws DT, Indirect Tax Laws IDT, Integrated Business Solutions (Multidisciplinary Case Study with Strategic Management) and IPCC/IPC Nov 2023 question papers for Accounting , Business, Law, Ethics & Communications , Cost Accounting & Financial Management CAFM, Taxation, Advanced Accounting , Auditing & Assurance, Information Technology & Strategic Management ITSM. Full Article
paper CA Final Direct Tax Laws and International Taxation (DT) Question Paper New Course Nov 2024 By www.caclubindia.com Published On :: Mon, 11 Nov 2024 12:36:57 GMT Download Direct Tax Laws & International Taxation (DT) Question Papers New Course Nov 2024 in PDF. For older question papers of CA final May 2024, Nov 2023, May 2023, Nov 2022, May 2022, Dec 2021, July 2021, Nov 2020, Nov 2019, May 2019, Nov 2018,CA final May 2018, Nov 2017, May 2017, CA final may 2016, CA final Nov 2016 check similar section. Previous years CA final Financial Reporting FR question papers can also be downloaded using Search. You can also search and download may 2015 IPCC & IPC question papers here. We are providing ca final question papers of may 2016 for Financial Reporting FR, Advanced Financial Management AFM, Advanced Auditing, Assurance And Professional Ethics, Direct Tax Laws DT, Indirect Tax Laws IDT,Integrated Business Solutions (Multidisciplinary Case Study with Strategic Management) and IPCC/IPC Nov 2023 question papers for Accounting, Business, Law, Ethics & Communications , Cost Accounting & Financial Management CAFM, Taxation, Advanced Accounting , Auditing & Assurance, Information Technology & Strategic Management ITSM. Full Article
paper What the newspapers think is important about Barack Obama By cheezburger.com Published On :: Thu, 28 May 2009 20:36:04 -0700 Full Article barack obama dogs healthcare importance iraq war
paper How pen and paper comes to the rescue in an IT crisis By www.bbc.com Published On :: Thu, 26 Sep 2024 23:04:07 GMT Firms are advised to practise operating with pens and paper in case of a computer meltdown. Full Article
paper The Papers: Welby quits and hospital chiefs get waiting times warning By www.bbc.com Published On :: Wed, 13 Nov 2024 01:24:57 GMT The resignation of the Archbishop of Canterbury and new performance measures for the NHS lead the papers. Full Article
paper Border-Gavaskar Trophy: Virat Kohli features on Aussie newspapers' front page, headlines in Hindi, Punjabi go viral By www.dnaindia.com Published On :: Tue, 12 Nov 2024 10:48:00 GMT The much anticipated Border-Gavaskar series between India and Australia will begin on November 22, with the first Test at Perth. Full Article Sports
paper Understanding clinical papers [Electronic book] / David Bowers, Allan House, David Owens, Bridgette Bewick. By encore.st-andrews.ac.uk Published On :: Chichester : John Wiley & Sons Inc., 2013. Full Article
paper Distance-based paper analytical device for multiplexed quantification of cytokine biomarkers using carbon dots integrated with molecularly imprinted polymer By pubs.rsc.org Published On :: Lab Chip, 2024, 24,2262-2271DOI: 10.1039/D4LC00055B, PaperKawin Khachornsakkul, Ruben Del-Rio-Ruiz, Lita Chheang, Wenxin Zeng, Sameer SonkusaleA carbon dots and dopamine-imprinted polymer was immobilized onto a distance-based paper channel for simultaneous detection of three cytokine biomarkers without requiring expensive reagents and instruments.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
paper A novel ratiometric design of microfluidic paper-based analytical device for the simultaneous detection of Cu2+ and Fe3+ in drinking water using a fluorescent MOF@tetracycline nanocomposite By pubs.rsc.org Published On :: Lab Chip, 2024, 24,2306-2316DOI: 10.1039/D3LC01045G, PaperSabah H. Al-Jaf, Sameera Sh. Mohammed Ameen, Khalid M. OmerOn-site monitoring of ions in drinking water is essential for safeguarding public health, ensuring high water quality, and preserving the ecological balance of aquatic ecosystems.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article