migration

HOLCIM accélère la migration de ses postes de travail vers Windows 7 avec IBM

IBM et Holcim France Benelux annoncent la migration vers Windows 7 des postes de travail de 2500 utilisateurs sur 286 sites en seulement trois mois grâce au savoir-faire d’IBM Global Technology Services.



  • Global Business Solutions

migration

Wimpie Nortje: Database migration libraries for PostgreSQL.

It may be tempting at the start of a new project to create the first database tables manually, or write SQL scripts that you run manually, especially when you first have to spend a significant amount of time on sifting through all the migration libraries and then some more to get it working properly.

Going through this process did slow me down at the start of the project but I was determined to use a migration tool because hunting inexplicable bugs that only happen in production just to find out there is a definition mismatch between the production and development databases is not fun. Using such a tool also motivates you to write both the setup and teardown steps for each table while the current design is still fresh in your mind.

At first I considered a standalone migration tool because I expect them to be very good at that single task. However, learning the idiosyncrasies of a new tool and trying to make it fit seamlessly into my development workflow seemed like more trouble than it is worth.

I decided to stick with a Common Lisp library and found the following seven that work with PostgreSQL and/or Postmodern:

I quickly discounted Crane and Mito because they are ORM (Object Relational Mapper) libraries which are way more complex than a dedicated migration library. Development on Crane have stalled some time ago and I don't feel it is mature enough for frictionless use yet. Mito declares itself as being in Alpha state; also not mature enough yet.

I only stumbled onto cl-mgr and Orizuru-orm long after making my decision so I did not investigate them seriously. Orizuru-orm is in any case an ORM which I would have discounted because it is too complex for my needs. CL-mgr looks simple, which is a good thing. It is based on cl-dbi which makes it a good candidate if you foresee switching databases but even if I discovered it sooner I would have discounted it for the same reason as CL-migrations.

CL-migrations looks very promising. It is a simple library focusing only on migrations. It uses clsql to interface with the database which bothered me because I already committed to using Postmodern and I try to avoid adding a lot of unused code to my projects. The positive side is that it interfaces to many different databases so it is a good candidate if you are not committed to using Postmodern. It is also a stable code base with no outstanding bug reports.

The two projects I focused on was Postmodern-passenger-pigeon and Database-migrations because they both use Postmodern for a database interface.

Postmodern-passenger-pigeon was in active development at the time and it seemed safer to use than Database-migrations because it can do dry runs, which is a very nice feature when you are upgrading your production database and face the possibility of losing data when things go awry. Unfortunately I could not get it working within a reasonable amount of time.

I finally settled on Database-migrations. It is a small code base, focused on one task, it is mature and it uses Postmodern so it does not pull in a whole new database interface into my project. There are however some less positive issues.

The first issue is a hindrance during development. Every time the migrations ASDF system (or the file containing it, as ASDF prefers that all systems be defined in a single file) is recompiled it adds all the defined migrations to the migrations list. Though each one will only be applied once to the DB it is still bothersome. One can then clear the list with (setf database-migrations::*migrations* nil) but then only newly modified migration files will be added. The solution then is to touch the .asd file after clearing the migrations list.

The second negative point is quite dangerous. The downgrade function takes a target version as parameter, with a default target of 0. This means that if you execute downgrade without specifying a target version you delete your whole database.

I am currently using Database-migrations and it works well for me. If for some reason I need to switch I will use cl-migrations.

Using Database-migrations

To address the danger of unintentionally deleting my database I created a wrapper function that does both upgrade and downgrade, and it requires a target version number.

Another practical issue I discovered is that upgrades and downgrades happen in the same order as they are defined in the migration file. If you create two tables in a single file where table 2 depends on table 1 then you can not revert / downgrade because Database-migrations will attempt to delete table 1 before table 2. The solution here is to use the def-queries-migration macro (instead of def-query-migration) which defines multiple queries simultaneously . If you get overwhelmed by a single definition that defines multiple tables the other option is to stick with one migration definition per file.




migration

Immigration detention is a public health hazard

As physicians who work in New York City hospitals, we are witnessing how COVID-19 is ravaging the communities we serve. The only way to slow this pandemic is to stop the transmission of the disease. Yet despite everything we know about how the virus spreads and the unprecedented sacrifices workers have made to slow the spread, Immigration and Customs Enforcement (ICE) continues to endanger the lives of over 40,000 immigrants in more than 200 jails and prisons nationally. Most people in immigration detention have committed no criminal offense and have been deemed by ICE to pose no danger, yet they are held arbitrarily pending disposition of their asylum claims or deportation orders.




migration

Immigration, Innovation, and Growth -- by Konrad B. Burchardi, Thomas Chaney, Tarek Alexander Hassan, Lisa Tarquinio, Stephen J. Terry

We show a causal impact of immigration on innovation and dynamism in US counties. To identify the causal impact of immigration, we use 130 years of detailed data on migrations from foreign countries to US counties to isolate quasi-random variation in the ancestry composition of US counties that results purely from the interaction of two historical forces: (i) changes over time in the relative attractiveness of different destinations within the US to the average migrant arriving at the time and (ii) the staggered timing of the arrival of migrants from different origin countries. We then use this plausibly exogenous variation in ancestry composition to predict the total number of migrants flowing into each US county in recent decades. We show four main results. First, immigration has a positive impact on innovation, measured by the patenting of local firms. Second, immigration has a positive impact on measures of local economic dynamism. Third, the positive impact of immigration on innovation percolates over space, but spatial spillovers quickly die out with distance. Fourth, the impact of immigration on innovation is stronger for more educated migrants.




migration

Popular pesticide throws off birds’ feeding and migration schedules

Delays during migration can imperil birds’ chances of a successful breeding season.




migration

Trump's new immigration freeze is just more of his tired political posturing

The Trump coronavirus immigration order shows he has yet to find a crisis he can't try to exploit for his own political gain.




migration

L.A. Times updates guidelines for covering immigration

The Los Angeles Times has announced new guidelines for covering immigration.




migration

World's biggest mass migration begins as China prepares to mark New Year

Three billion trips to be made during Spring Harvest




migration

Review: 'The Infiltrators' is an inventive hybrid of immigration drama and heist thriller

Directed by Alex Rivera and Cristina Ibarra, "The Infiltrators" is a mix of documentary footage and staged fiction scenes to tell the story of undocumented young immigration activists taking their work inside a Florida detention facility.




migration

It’s not racist to be concerned about a weak immigration policy, says PETER HILL



FOLLOWING the Windrush scandal the NHS says that its records will no longer be used to track down illegal immigrants.




migration

Witnessing migration in action is to see a natural miracle, says JOHN INGHAM



THE summer that just keeps giving had the swallows all in a flutter last week. On the south coast of the Isle of Wight hundreds streamed past me and my family as we walked over the downs, enchanted by dart-like birds racing over the white cliffs and the green sward. Yet they were flying north-east instead of south towards Africa. Some were even coming in from the sea instead of heading out over the Channel.




migration

Migrations Engineer

Our customer in New York City is looking for an engineer to migrate their entire infrastructure from Lotus Note 8.5 to Windows Office 365. The project is expected to last at least 6 months. The right candidate must have experience performing Windows Office 365 migrations at an enterprise level, m




migration

Coronavirus: Immigration detention centres in crisis

There are Covid-19 outbreaks in supply-strapped detention centres across the US.




migration

Rihanna has a message for President Trump about immigration

The native of Barbados apparently doesn't like Trump's immigration policies.




migration

Trump’s immigration policies speak louder than his racist, xenophobic words

Sadly, the most recent horrors are not an aberration.




migration

The 1930s were a dark period for immigration policies. There’s one way today’s could be worse.

Trump has gutted the asylum system that grew in part out of our shame over our heartless refugee policies in the 1930s.




migration

Stephen Miller is right about immigration — but not in the way that he means

Immigration does touch on many other policy issues, though maybe not in the manner he suggests.




migration

Trump found a way to simultaneously sabotage our health-care and immigration systems

He just took out two birds with one proclamation.




migration

Trump has bulldozed over Congress on immigration. Will lawmakers ever act?

The president and his team of unelected bureaucrats have siphoned power away from the legislature.




migration

There’s no other way to explain Trump’s immigration policy. It’s just bigotry.

The administration has cracked down on all migrants, even those with the most to contribute.




migration

Why Tom Cotton’s immigration idea makes no sense

America only benefits from U.S.-trained scientists.




migration

America’s Immigration Battle By the Numbers

The U.S. has deported an average of 403,500 people each year during the Obama administration. What else do the numbers say about the nation's immigration system?




migration

Is It Too Late for Obama On Immigration Reform?

Unless the Supreme Court acts fast, the window might be closed for President Obama on immigration reform.




migration

Webinar: COVID-19 and the Impact on Latin American Migration

Research Event

14 May 2020 - 3:00pm to 4:00pm
Add to Calendar

Ambassador Arturo Sarukhan, Associate Fellow, US and the Americas Programme, Chatham House; Mexican Ambassador to the US, 2007 - 13
Professor Anita Isaacs, Benjamin R. Collins Professor of Social Sciences, Haverford College
Chair: Dr Christopher Sabatini, Senior Research Fellow for Latin America, US and the Americas Programme, Chatham House

The US government recently announced restrictions on immigration, stating the new measures were necessary due to COVID-19 and the effect the pandemic has had on the US economy. But what is the role of immigrants in the essential official and unofficial services in the COVID-19 stay-at-home era? How is COVID-19 affecting immigration from Central America and Mexico? 

Separately, there have also been instances of outbreaks among detainees in US Immigration and Customs Enforcement centers and claims that immigrants who are returning to Guatemala are spreading the virus. How have US immigration policies affected infection rates in Central America and Mexico and among its citizens?

Arturo Sarukhan, Mexican Ambassador to the US from 2007 - 13, and Anita Isaacs, Benjamin R. Collins Professor of Social Sciences, Haverford College, will join us to discuss the impact COVID-19 is having on migrants.

Chatham House would like to thank BTG Pactual, Cairn Energy plc, Diageo plc, Equinor, Fresnillo Management Services, HSBC Holdings plc and Wintershall Dea for their generous support of the Latin America Initiative.

This event is scheduled to take place from 15:00 – 16:00 BST.

US and Americas Programme




migration

The Morass of Central American Migration: Dynamics, Dilemmas and Policy Alternatives

Invitation Only Research Event

22 November 2019 - 8:15am to 9:30am

Chatham House | 10 St James's Square | London | SW1Y 4LE

Event participants

Anita Isaacs, Professor of Political Science, Haverford College; Co-Director, Migration Encounters Project
Juan Ricardo Ortega, Principal Advisor for Central America, Inter-American Development Bank
Chair: Amy Pope, Associate Fellow, Chatham House; US Deputy Homeland Security Adviser for the Obama Administration (2015-17)

2019 has seen a record number of people migrating from Central America’s Northern Triangle – an area that covers El Salvador, Guatemala and Honduras. Estimates from June 2019 have placed the number of migrants at nearly double of what they were in 2018 with the increase in numbers stemming from a lack of economic opportunity combined with a rise in crime and insecurity in the region. The impacts of migration can already be felt within the affected states as the exodus has played a significant role in weakening labour markets and contributing to a ‘brain drain’ in the region. It has also played an increasingly active role in the upcoming US presidential election with some calling for more security on the border to curb immigration while others argue that a more effective strategy is needed to address the sources of migration. 

What are the core causes of Central American migration and how have the US, Central American and now also Mexican governments facilitated and deterred migration from the region? Can institutions be strengthened to alleviate the causes of migration? And what possible policy alternatives and solutions are there that could alleviate the pressures individuals and communities feel to migrate?   

Anita Isaacs, professor of Political Science at Haverford College and co-director of the Migration Encounters Project, and Juan Ricard Ortega, principal advisor for Central America at the Inter-American Development Bank, will join us for a discussion on the core drivers of migration within and across Central America.

Attendance at this event is by invitation only. 

Event attributes

Chatham House Rule

Department/project

US and Americas Programme




migration

Coronavirus in Latin America and Mexico: Infection Rates, Immigration and Policy Responses

Invitation Only Research Event

25 March 2020 - 4:00pm to 5:00pm

Event participants

Jude Webber, Mexico and Central America Correspondent, Financial Times
Michael Stott, Latin America Editor, Financial Times
Chair: Dr Christopher Sabatini, Senior Research Fellow for Latin America, US and the Americas Programme, Chatham House

This event is part of the Inaugural Virtual Roundtable Series on the US, Americas and the State of the World and will take place virtually only.  Participants should not come to Chatham House for these events

US and Americas Programme




migration

Webinar: COVID-19 and the Impact on Latin American Migration

Research Event

14 May 2020 - 3:00pm to 4:00pm
Add to Calendar

Ambassador Arturo Sarukhan, Associate Fellow, US and the Americas Programme, Chatham House; Mexican Ambassador to the US, 2007 - 13
Professor Anita Isaacs, Benjamin R. Collins Professor of Social Sciences, Haverford College
Chair: Dr Christopher Sabatini, Senior Research Fellow for Latin America, US and the Americas Programme, Chatham House

The US government recently announced restrictions on immigration, stating the new measures were necessary due to COVID-19 and the effect the pandemic has had on the US economy. But what is the role of immigrants in the essential official and unofficial services in the COVID-19 stay-at-home era? How is COVID-19 affecting immigration from Central America and Mexico? 

Separately, there have also been instances of outbreaks among detainees in US Immigration and Customs Enforcement centers and claims that immigrants who are returning to Guatemala are spreading the virus. How have US immigration policies affected infection rates in Central America and Mexico and among its citizens?

Arturo Sarukhan, Mexican Ambassador to the US from 2007 - 13, and Anita Isaacs, Benjamin R. Collins Professor of Social Sciences, Haverford College, will join us to discuss the impact COVID-19 is having on migrants.

Chatham House would like to thank BTG Pactual, Cairn Energy plc, Diageo plc, Equinor, Fresnillo Management Services, HSBC Holdings plc and Wintershall Dea for their generous support of the Latin America Initiative.

This event is scheduled to take place from 15:00 – 16:00 BST.

US and Americas Programme




migration

Webinar: COVID-19 and the Impact on Latin American Migration

Research Event

14 May 2020 - 3:00pm to 4:00pm
Add to Calendar

Ambassador Arturo Sarukhan, Associate Fellow, US and the Americas Programme, Chatham House; Mexican Ambassador to the US, 2007 - 13
Professor Anita Isaacs, Benjamin R. Collins Professor of Social Sciences, Haverford College
Chair: Dr Christopher Sabatini, Senior Research Fellow for Latin America, US and the Americas Programme, Chatham House

The US government recently announced restrictions on immigration, stating the new measures were necessary due to COVID-19 and the effect the pandemic has had on the US economy. But what is the role of immigrants in the essential official and unofficial services in the COVID-19 stay-at-home era? How is COVID-19 affecting immigration from Central America and Mexico? 

Separately, there have also been instances of outbreaks among detainees in US Immigration and Customs Enforcement centers and claims that immigrants who are returning to Guatemala are spreading the virus. How have US immigration policies affected infection rates in Central America and Mexico and among its citizens?

Arturo Sarukhan, Mexican Ambassador to the US from 2007 - 13, and Anita Isaacs, Benjamin R. Collins Professor of Social Sciences, Haverford College, will join us to discuss the impact COVID-19 is having on migrants.

Chatham House would like to thank BTG Pactual, Cairn Energy plc, Diageo plc, Equinor, Fresnillo Management Services, HSBC Holdings plc and Wintershall Dea for their generous support of the Latin America Initiative.

This event is scheduled to take place from 15:00 – 16:00 BST.

US and Americas Programme




migration

Islam, Immigration and Identity in Europe




migration

Migration and Health: Barriers and Means to Achieving Universal Health Coverage




migration

CBD News: Message by Dr. Ahmed Djoghlaf, Executive Secretary of the Convention on Biological Diversity, on the occasion of the World Migratory Bird Day 2009: "Barriers to Migration", 9 - 10 May 2009.




migration

CBD News: Message of the Executive Secretary of the Convention on Biological Diversity, Dr. Cristiana Pasca Palmer, on the occasion of International Mountain Day 11 December 2017: "Mountains under pressure: climate, hunger and migration"




migration

CBD News: Rachel Carson, the late American biologist and conservationist, suggested "there is symbolic as well as actual beauty in the migration of the birds... something infinitely healing in the repeated refrains of nature - the assurance that dawn




migration

What startups need to know about new UK immigration rules

The government has unveiled its new points-based immigration system, due to come into force in 2021, we break down what it means for the UK startup sector




migration

Immigration services to resume

The Immigration Department today announced that aside from its Smart Identity Card Replacement Centres (SIDCC) service and passenger immigration clearance service, it will resume full public services on May 4.

 

Due to the COVID-19 epidemic, the services of the nine SIDCCs had been suspended earlier.

 

Around 640,000 people could not replace their Hong Kong identity cards during their specified periods and about 90,000 people are waiting to collect their new identity cards.

 

To allow affected people to apply for and collect identity cards in an orderly manner, the SIDCCs will first provide identity card collection service and arrange applicants born in 1957 to 1961 who had made appointments before to have their cards replaced once the service resumes.

 

Other applicants are advised to make appointments to replace their identity cards if they have not done so before.

 

The department plans to revise designated replacement periods for identity card holders born in 1957 to 1963 and between 1970 and 1976.

 

Details will be announced later. For enquiries regarding identity cards, call 3521 6565.

 

Additionally, passenger immigration clearance services at immigration control points except for the Hong Kong International Airport, Shenzhen Bay and Hong Kong-Zhuhai-Macao Bridge Control Points will remain suspended until further notice.

 

Call 2824 6111 or send an email for enquiries.




migration

Real-time visualization of solid-phase ion migration

(University of Science and Technology of China) Researchers from University of science and technology of China has shed new lights on the topic of solid-phase ion migration. Researchers demonstrated a unique in-situ strategy for visualizing the dynamic solid-phase ion migration between nanostructures with nanogap at the atomic scale. The research article entitled "Real-Time Visualization of Solid-Phase Ion Migration Kinetics on Nanowire Monolayer" was published in Journal of the American Chemical Society on April 29th.




migration

Migration Deals Risk Undermining Global Refugee Protection

13 April 2018

Amanda Gray Meral

Associate Fellow, International Law Programme
While some aspects of agreements like that between the EU and Turkey reflect a genuine effort to cooperate in addressing the needs of refugees, other elements risk undermining the very essence of the global refugee protection regime.

2018-04-13-Lesbos.jpg

A boat carrying migrants approaches shore after making the crossing from Turkey to the Greek island of Lesbos in November 2015. Photo: Getty Images.

Last month the European Commission proposed that the EU should mobilize the next tranche of funding for Turkey (€3 billion) under the EU–Turkey deal agreed in 2016. The deal is part of a rapidly developing strategy on the part of the EU to improve cooperation on migration issues with countries of origin as well as those through which migrants and refugees transit en route to Europe. Since 2015, the EU has ramped up negotiations, with the New Partnership Framework underpinning arrangements with countries such as Niger, Mali and Ethiopia, and endorsing a memorandum of understanding between Italy and Libya in February 2017.

A common thread that runs across all of these deals is their focus on containment in exchange for funding, rather than a principled approach to refugee protection. For example, the EU has committed around €6 billion to Turkey as a contribution towards the cost of humanitarian assistance for the over 3 million Syrian refugees residing there. This funding also operates as an incentive for Turkey to take back all refugees and migrants who have irregularly arrived in Greece via Turkey since the deal entered effect.

Similarly, the EU is providing financial support to Libya in exchange for its cooperation in reducing the flow of migrants and refugees towards Europe, while the New Partnership Framework aims to reduce the number of migrants and refugees departing for Europe in exchange for EU aid. While financial incentives geared towards containment do not amount to new policy, with the increasing number of deals being negotiated, the use of such a strategy appears to be both accelerating and becoming more explicit.

An effective investment?

Implementation of these deals has been hindered by obligations under international law, raising questions not only as to their legality but also their value for money.

Under the EU–Turkey deal, refugees arriving in Greece irregularly were to be returned to Turkey, with an equal number of Syrian refugees resettled to Europe in exchange. However, implementation of this aspect of the deal has been limited.

Under EU asylum law, Greece is obliged to provide access to asylum procedures for those arriving on its shores. Given that most arrivals from Turkey came from refugee-producing countries (including Syria, Afghanistan and Iraq), an individualized assessment of ‘safe third country’ is required before any possible return to Turkey can take place. This requires a finding that Turkey can guarantee effective access to protection for the individual in question, including protection against refoulement (i.e. forced return to a country where he or she is at risk of serious harm or persecution). By the end March 2018, only 2,164 people had been returned to Turkey.

As for Italy, with EU support, under the MOU with Libya it has been training as well as providing funding and logistical support to the Libyan coastguard – including an Italian naval presence in Libyan waters – to intercept boats in the Mediterranean. Given the mounting evidence of abuse of migrants and refugees, whether by Libyan coastguards or inside Libyan detention centres, this raises questions as to whether the support being provided by Italy and the EU amounts to a breach of international law.

Despite concerns about the protection risks for refugees, advocates of such deals claim they have the potential to prevent dangerous journeys, saving lives and interrupting the business model of smugglers. Numbers crossing the Mediterranean have indeed dropped since the deals were agreed. However, in Libya it has created an ‘anti-smuggling’ market which, despite leading to a reduction of migration in the short term, may not be sustainable in the long term if it drives conflict between various non-state actors.

In the case of the EU–Turkey deal, while it has led to a fall in arrivals to the Greek islands in the first six months of 2017, there is also evidence that smugglers were already adapting their routes, forcing refugees and migrants to travel on the more dangerous central Mediterranean route.

For now, at least, these deals appear to have gained significant popular support within the EU. Italy’s approaches in Libya, for example, have been broadly backed by the Italian public – unsurprising given that some polls indicate 50 percent of the Italian population believe migrants to be a threat to public security. However, the drivers of public attitudes towards refugees and migration are complex and, as noted in a policy brief published under the Chatham House–ODI Forum on Refugee and Migration Policy, influenced in part by narratives driven by politicians and the media.

What some of these deals have achieved is the significant flow of aid money towards job creation and economic opportunities for refugees, incentivizing policy change in some contexts and producing real benefits for the refugees concerned (while reducing pressures on them to move onwards via dangerous journeys).

A prominent example is the Jordan Compact, a 2016 agreement between Jordan, the EU and international financial institutions including the World Bank to improve the livelihoods and education of Syrian refugees inside Jordan. While challenges in its implementation remain, including concerns about labour rights, the Jordan Compact has resulted in real improvements in education and access to the labour market for Syrian refugees. The Jordanian government has made policy concessions on access to work permits for Syrian refugees, removing some of the barriers that prevented refugees accessing jobs, while the EU has committed to ease trade barriers for goods produced in Jordanian factories on condition they hire a percentage of Syrian refugees.

Likewise, the EU–Turkey deal’s most successful component has been its financial contribution of €3 billion of aid under the EU Facility for Refugees towards support for the 3.7 million Syrian refugees currently being hosted by Turkey. This includes €1 billion allocated to the Emergency Social Safety Net, described by the European Commission as the ‘largest single humanitarian project in the history of the EU’, directly impacting the livelihoods of some 1.1 million vulnerable refugees.

Moving ahead

While some aspects of these deals reflect a genuine effort to cooperate in addressing the needs of refugees, other elements risk undermining the very essence of the global refugee protection regime.

The diplomatic squabble over a proposed refugee ‘swap’ of 1,250 refugees between the US and Australia in February 2017 highlights the danger of refugees becoming bargaining chips. Similarly, the Kenyan government’s announcement that it would close Dadaab refugee camp in late November 2016 cited the EU-Turkey deal as justification. Migration partnerships which emphasise the securing of EU borders against refugee arrivals may diminish the willingness of states in the Global South to continue to host large numbers of refugees.

While the positive aspects of such deals deserve acknowledgement, understanding their impact on refugee protection must be given greater attention. This is vital not only to ensure their workability but also to ensure that those countries who spearheaded the creation of the global refugee protection regime do not end up undermining its existence.




migration

Forum on Refugee and Migration Policy - Roundtable 3

Invitation Only Research Event

14 May 2018 - 10:00am to 5:30pm

Chatham House | 10 St James's Square | London | SW1Y 4LE London

This roundtable focuses on the economic dimensions of displacement and migration and brings together an international group of experts from government, international organizations, civil society, research institutes and the private sector.   

The event was co-hosted with the Overseas Development Institute.

Event attributes

Chatham House Rule




migration

A flexible network of vimentin intermediate filaments promotes migration of amoeboid cancer cells through confined environments [Cell Biology]

Tumor cells can spread to distant sites through their ability to switch between mesenchymal and amoeboid (bleb-based) migration. Because of this difference, inhibitors of metastasis must account for each migration mode. However, the role of vimentin in amoeboid migration has not been determined. Because amoeboid leader bleb–based migration (LBBM) occurs in confined spaces and vimentin is known to strongly influence cell-mechanical properties, we hypothesized that a flexible vimentin network is required for fast amoeboid migration. To this end, here we determined the precise role of the vimentin intermediate filament system in regulating the migration of amoeboid human cancer cells. Vimentin is a classic marker of epithelial-to-mesenchymal transition and is therefore an ideal target for a metastasis inhibitor. Using a previously developed polydimethylsiloxane slab–based approach to confine cells, RNAi-based vimentin silencing, vimentin overexpression, pharmacological treatments, and measurements of cell stiffness, we found that RNAi-mediated depletion of vimentin increases LBBM by ∼50% compared with control cells and that vimentin overexpression and simvastatin-induced vimentin bundling inhibit fast amoeboid migration and proliferation. Importantly, these effects were independent of changes in actomyosin contractility. Our results indicate that a flexible vimentin intermediate filament network promotes LBBM of amoeboid cancer cells in confined environments and that vimentin bundling perturbs cell-mechanical properties and inhibits the invasive properties of cancer cells.




migration

The Morass of Central American Migration: Dynamics, Dilemmas and Policy Alternatives

Invitation Only Research Event

22 November 2019 - 8:15am to 9:30am

Chatham House | 10 St James's Square | London | SW1Y 4LE

Event participants

Anita Isaacs, Professor of Political Science, Haverford College; Co-Director, Migration Encounters Project
Juan Ricardo Ortega, Principal Advisor for Central America, Inter-American Development Bank
Chair: Amy Pope, Associate Fellow, Chatham House; US Deputy Homeland Security Adviser for the Obama Administration (2015-17)

2019 has seen a record number of people migrating from Central America’s Northern Triangle – an area that covers El Salvador, Guatemala and Honduras. Estimates from June 2019 have placed the number of migrants at nearly double of what they were in 2018 with the increase in numbers stemming from a lack of economic opportunity combined with a rise in crime and insecurity in the region. The impacts of migration can already be felt within the affected states as the exodus has played a significant role in weakening labour markets and contributing to a ‘brain drain’ in the region. It has also played an increasingly active role in the upcoming US presidential election with some calling for more security on the border to curb immigration while others argue that a more effective strategy is needed to address the sources of migration. 

What are the core causes of Central American migration and how have the US, Central American and now also Mexican governments facilitated and deterred migration from the region? Can institutions be strengthened to alleviate the causes of migration? And what possible policy alternatives and solutions are there that could alleviate the pressures individuals and communities feel to migrate?   

Anita Isaacs, professor of Political Science at Haverford College and co-director of the Migration Encounters Project, and Juan Ricard Ortega, principal advisor for Central America at the Inter-American Development Bank, will join us for a discussion on the core drivers of migration within and across Central America.

Attendance at this event is by invitation only. 

Event attributes

Chatham House Rule

Department/project

US and Americas Programme




migration

Coronavirus in Latin America and Mexico: Infection Rates, Immigration and Policy Responses

Invitation Only Research Event

25 March 2020 - 4:00pm to 5:00pm

Event participants

Jude Webber, Mexico and Central America Correspondent, Financial Times
Michael Stott, Latin America Editor, Financial Times
Chair: Dr Christopher Sabatini, Senior Research Fellow for Latin America, US and the Americas Programme, Chatham House

This event is part of the Inaugural Virtual Roundtable Series on the US, Americas and the State of the World and will take place virtually only.  Participants should not come to Chatham House for these events

US and Americas Programme




migration

Webinar: COVID-19 and the Impact on Latin American Migration

Research Event

14 May 2020 - 3:00pm to 4:00pm
Add to Calendar

Ambassador Arturo Sarukhan, Associate Fellow, US and the Americas Programme, Chatham House; Mexican Ambassador to the US, 2007 - 13
Professor Anita Isaacs, Benjamin R. Collins Professor of Social Sciences, Haverford College
Chair: Dr Christopher Sabatini, Senior Research Fellow for Latin America, US and the Americas Programme, Chatham House

The US government recently announced restrictions on immigration, stating the new measures were necessary due to COVID-19 and the effect the pandemic has had on the US economy. But what is the role of immigrants in the essential official and unofficial services in the COVID-19 stay-at-home era? How is COVID-19 affecting immigration from Central America and Mexico? 

Separately, there have also been instances of outbreaks among detainees in US Immigration and Customs Enforcement centers and claims that immigrants who are returning to Guatemala are spreading the virus. How have US immigration policies affected infection rates in Central America and Mexico and among its citizens?

Arturo Sarukhan, Mexican Ambassador to the US from 2007 - 13, and Anita Isaacs, Benjamin R. Collins Professor of Social Sciences, Haverford College, will join us to discuss the impact COVID-19 is having on migrants.

Chatham House would like to thank BTG Pactual, Cairn Energy plc, Diageo plc, Equinor, Fresnillo Management Services, HSBC Holdings plc and Wintershall Dea for their generous support of the Latin America Initiative.

This event is scheduled to take place from 15:00 – 16:00 BST.

US and Americas Programme




migration

Should doctors boycott working in Australia’s immigration detention centres?

However well intentioned, working in detention centres amounts to complicity in torture, says David Berger, a district medical officer in emergency medicine at Broome Hospital in Australia. However, Steven Miles, chair in bioethics at the University of Minnesota thinks that they play an important role in telling the world about conditions in...




migration

What forced migration can tell us about diabetes

Worldwide, the rate of type II diabetes is estimated to be around 1 in 11 people - about 9%. For the Pima people of Arizona, 38% of the adult population have the condition - but across the border in Mexico, the rate drops down to 7%. The difference between the groups is their life experience - one side displaced, the other on their traditional...




migration

Twenty Five Years Later: Reflecting on the Immigration Act of 1990

A discussion marking the 25th anniversary of the 1990 Immigration Act, where experts examinine the history of the legislation, how it was accomplished politically, and the stakeholders and issues that were critical to its passage.




migration

13th Annual Immigration Law & Policy Conference

With issues of immigration policy very much at the forefront of the 2016 elections, this annual conference offers policy and legal analysis on key immigration topics facing the country and the incoming administration and Congress in 2017.




migration

13th Annual Immigration Law & Policy Conference

The 13th annual Immigration Law & Policy Conference offered policy and legal analysis on key immigration topics, including: the election and the future of immigration policy; refugee resettlement in the United States; immigration detention and enforcement; and the impacts of the Supreme Court opinion in the important U.S. vs Texas case




migration

Immigration Data Matters: How to Find the Most Accurate Resources

With immigration increasingly visible in the news and the political space in the United States and internationally, getting access to accurate, high-quality data is essential to understand immigration’s demographic effects and impacts on the economy, education and labor systems, and communities. This event marks the release of the Immigration Data Matters guide.




migration

It’s Relative: A Crosscountry Comparison of Family-Migration Policies and Flows

As policymakers in a number of countries, the United States among them, debate limiting family-based immigration, this issue brief explores family-migration trends and policies in the United States, Australia, Canada, the United Kingdom, and several other European countries. Family admissions play a key role, even in countries that prioritize economic or other immigration streams.




migration

A Walk-Through on How to Find Top Immigration Stats on the Web

Where can you find the most accurate statistics on some of the top immigration issues—ranging from the size of immigrant and emigrant populations, to humanitarian and labor flows, naturalization rates, enforcement statistics, remittances, and more? In this brief video, Jeanne Batalova, who manages the Migration Policy Institute’s Migration Data Hub, walks you through the Immigration Data Matters guide developed by MPI and the Population Reference Bureau.