White collar boxing training offered to fundraisers.

A charity concert has raised £700 for the Edgbaston-based charity Ammalife.

Final call for STEM organisations to apply for grant funding.

Applications now open for life-changing opportunity.

Ball helps community group.

Transport firm raise record amount for childrens charity.

Pallet-Track golf day tees up £8,000 for Marie Curie.

Pedal power replaces horse power on London 2 Paris charity bike ride.

There comes a point in every podcast when it's necessary to say a URL. If for nothing else, at least your podcast's own home on the Internet. (And you should have a domain for your podcast!)

The post 11 Tips for Sharing URLs in Your Podcast first appeared on The Audacity to Podcast.

For those able to do so, donating or fundraising for charities seems like a good idea, especially with the holidays coming up. For USAmericans, this has the dual function of denying your tax $$ to the incoming government and helping the people that government wishes to harm. I thought it might be nice to crowdsource a thread of charities which do useful work for the communities under threat. Below are a few to start us off:

RAICES - Texas-based group helping immigrants and refugees United We Dream - working for immigrant youth Trans Lifeline - phone hotline, microgrants and legal help for trans folk The Trevor Project - helping LGBTQ+ youth NAACP legal defense fund - among other things, very useful for arrested racial justice protesters Southern Poverty Law Center - social, racial and economic justice National Network of Abortion Funds A couple of election integrity charities, since that will be crucial in the near future: Lawyers' Committee for Civil Rights Under Law - civil rights, election integrity, voting rights VoteRiders - Election integrity, voting rights But that's just a few! Please post the orgs you know of doing good and useful work.

Through your generosity, precious individuals—people like Rej—are being introduced daily to the Prince of Peace and lives are being transformed for His kingdom.

Updated at 7:57 p.m. ET To help figure out the U.S. citizenship status of every adult living in the country, the Trump administration has been accumulating driver's license information from states including South Dakota, NPR has learned. South Dakota Public Safety Secretary Craig Price — who was appointed to President Trump's commission on law enforcement this year — signed an agreement in April to share information from driver's licenses and state ID cards with the U.S. Census Bureau, according to a copy of the memorandum of understanding the state's Department of Public Safety provided to NPR. In the past year since the Trump administration failed in its attempt to add the now-blocked citizenship question to 2020 census forms, the Census Bureau has been gathering state and federal records under directives from Commerce Secretary Wilbur Ross , who oversees the bureau, and an executive order Trump issued in July 2019 . In addition to allowing states to redistrict using the number of

Bob didn’t feel right about the ecstatic gibberish he was hearing in church. When he stumbled across the Amazing Facts website, the truths he heard changed his life. The devil uses counterfeits to deceive many who are looking for trustworthy answers to their Bible questions. However, God can use you and your gifts to uncover Satan’s deceptions and uphold essential truth. Thank you for being a beacon of light in this dark world!

The British-Indian novelist and journalist spoke with Eleanor Wachtel in 2017.

Matilda Finnegan is inviting locals for an afternoon tea which she hopes will help land her a place in a top beauty contest

A woman from Cambodia who is dying scam you.

A response from Fang Wengen, the lawyer of Mrs Yang Huiyan

Mrs Sulak is dying, but she will always stay alive, long enough for someone to reply. That's 419 scam law!

Margaret Loughrey wants to give you some of her winnings... not really... 419 scammers are piggybacking on her story, which is already OLD news.

The Women’s Resource Centre [WRC], in partnership with SCARS and the Centre Against Abuse [CAA] launched a new community support group for women – SASS – Sexual Assault Survivors Support Group. A spokesperson said, “As we close Sexual Assault Awareness month, which is observed annually during the month of April, The Women’s Resource Centre [WRC], […]

The St. George’s Club Hotel will support a United Kingdom charity golf tournament organized by Rosemary Lockwood, the Lady Captain of Wollaton Park Golf Club in England. A spokesperson said, “The St. George’s Club Hotel has agreed to support a UK charity golf tournament being organized by a long-time Bermuda visitor Rosemary Lockwood, Lady Captain […]

The Swan’s Charity 5K race is set to take place on Sunday, October 20 at John Smith’s Bay, supporting the Crossroads Warriors Community Club. A spokesperson said, “This weekend is the Swan’s Charity 5K race – Sunday, Oct. 20, 2024. This race runs along the scenic route of South Shore and Harrington Sound Road, starting […]

Domico Watson and Marielle Beaulieu raced to victory 2024 Swan’s Charity 5K race this weekend. Watson secured his second victory of the season with a winning time of 18:16. Tim Price followed closely, finishing second with a time of 18:43, while Kwame Curling took third place with a time of 18:59. In the women’s division, […]

The Wollaton Park Captains Charity Open is set to be held on Friday [Sept 13], with proceeds to benefit cancer-related charities. A spokesperson said, “For more than a century, Bermuda’s biggest fans have been our repeat visitors who have fallen in love with our beloved country. “Ever wonder what motivates a person[s] or families to […]

Have you got friends or family wondering what this astral projecting interest of yours is all about?

Do you ?nd it tough to explain in a simple, accessible way?

Well here’s a little site that may work well – especially for your peeps who like to keep a beat.

WARNING: Volume. RIP headphone users.

read more

Evaluation report for the inter-authority learning exchange between Shetland Islands, Falkirk and Glasgow Councils throughcare and aftercare teams. In February 2014 a member of the Throughcare and Aftercare team from Shetland, spent two weeks in each host authority as a means of developing and sharing practice, experience and learning. The report describes the planning process, in-situ experience, and post-exchange learning of participants, it also report highlights the positive learning outcomes and benefits achieved for all participating local authorities. The report identifies ideas for future applications of such a learning and practice exchange model to improve practice for looked after young people and care leavers.

Meta has been fined 21.62 billion won ($15.67 million) by South Korea's data privacy watchdog for illegally collecting sensitive personal information from Facebook users, including data about their political views and sexual orientation, and sharing it with advertisers without their consent. The country's Personal Information Protection Commission (PIPC) said Meta gathered information such as

In honor of his parents, Chemistry Nobel Laureate David MacMillan has founded The May and Billy MacMillan Foundation to provide educational opportunities for financially disadvantaged students in Scotland.

Daniel Khalife told jurors at his trial that he cannot remember the document in question.

The Magic Cottage was the epicentre of the blaze which broke out in Abergavenny on Sunday night.

The former Rangers and Liverpool star said charity fundraising allowed people to see "the real me".

The quirky folks at Fodor’s let me share some of the world’s weirdest plants, fungi, and microorganisms to inspire your #plantnerd bucket list (I’ve seen 5 out of 10 of these weirdos out in the wild!) 10 Plants From Around the World That Will Upset and Delight | Fodor’s Travel

The article EIT Elsewhere | Sharing the World’s Weirdest Plants on Fodor’s Travel originated at EverInTransit.com

Animals can sense the presence of microbes in their tissues and mobilize their own defenses by recognizing and responding to conserved microbial structures (often called microbe-associated molecular patterns (MAMPs)). Successful host defenses may kill the invaders, yet the host animal may fail to restore homeostasis if the stimulatory microbial structures are not silenced. Although mice have many mechanisms for limiting their responses to lipopolysaccharide (LPS), a major Gram-negative bacterial MAMP, a highly conserved host lipase is required to extinguish LPS sensing in tissues and restore homeostasis. We review recent progress in understanding how this enzyme, acyloxyacyl hydrolase (AOAH), transforms LPS from stimulus to inhibitor, reduces tissue injury and death from infection, prevents prolonged post-infection immunosuppression, and keeps stimulatory LPS from entering the bloodstream. We also discuss how AOAH may increase sensitivity to pulmonary allergens. Better appreciation of how host enzymes modify LPS and other MAMPs may help prevent tissue injury and hasten recovery from infection.

Aloïs Dusuel
Dec 9, 2020; 0:jlr.RA120000704v1-jlr.RA120000704
Research Articles

Bacterial lipopolysaccharides (LPSs or endotoxins) can bind most proteins of the lipid transfer/LPS-binding protein (LT/LBP) family in host organisms. The LPS-bound LT/LBP proteins then trigger either an LPS-induced proinflammatory cascade or LPS binding to lipoproteins that are involved in endotoxin inactivation and detoxification. Cholesteryl ester transfer protein (CETP) is an LT/LBP member, but its impact on LPS metabolism and sepsis outcome is unclear. Here, we performed fluorescent LPS transfer assays to assess the ability of CETP to bind and transfer LPS. The effects of intravenous (iv) infusion of purified LPS or polymicrobial infection (cecal ligation and puncture [CLP]) were compared in transgenic mice expressing human CETP and wild-type mice naturally having no CETP activity. CETP displayed no LPS transfer activity in vitro, but it tended to reduce biliary excretion of LPS in vivo. The CETP expression in mice was associated with significantly lower basal plasma lipid levels and with higher mortality rates in both models of endotoxemia and sepsis. Furthermore, CETPTg plasma modified cytokine production of macrophages in vitro. In conclusion, despite having no direct LPS binding and transfer property, human CETP worsens sepsis outcomes in mice by altering the protective effects of plasma lipoproteins against endotoxemia, inflammation, and infection.

South-South Cooperation is the mutual sharing and exchange of development solutions - knowledge, experiences and good practices, policies, technology and resources - between and among countries in the global [...]

Eliminates the Cost and Complexity of Maintaining Online Parts Catalogs; Improves Search, Navigation, and Communication for Engineers Seeking 3D Part Models

Twice a week, 60 to 80 children receive a meal and learn about Jesus, the Bread of Life, through OM Panama’s Pan de Vida programme.

A man gives his life to Jesus and is used greatly by God during an international outreach in Panama.

The Passover season leads to a young Israeli woman asking about the Passover Lamb.

OM Pakistan goes into bazaars, streets and houses with literature about God to meet those eager to learn more.

OM Mexico brings the gospel to the rural Guarijios tribe during the Christmas season.

Two North Africans first experience OM on short-term outreaches; now they lead others to do the same.

Worker shares how OM’s storytelling course revitalised her English classes and friendships.

OM Hong Kong hosts a Christmas party on 23 December 2011 for Pakistani women and children.

OM Hong Kong has reached out to South Asian immigrants for more than a year now. One worker shares about the challenges they face.

In partnership with the Hope Centre in Durrës, food and supplies were handed out to widows, divorced women and poor families on Women's Day.