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Discomfort and Pain in Newborns With Myelomeningocele: A Prospective Evaluation

Active termination of life in newborns with myelomeningocele because of assumed suffering in these newborns has been extensively discussed. However, the level of discomfort and pain in these newborns has never been substantially assessed.

This is the first study presenting quantitative data on discomfort and pain in newborns with myelomeningocele. Therefore, it can be of guidance in the choice of treatment: either active treatment or palliative care in the context of end-of-life decisions. (Read the full article)




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Barriers to Conducting Advance Care Discussions for Children With Life-Threatening Conditions

Previous studies have identified barriers to providing optimal pediatric palliative care, including general communication issues between clinicians and family members. However, there is a paucity of data regarding the barriers specifically relating to advance care discussions.

This study identifies significant barriers to advance care discussions for children with life-threatening conditions. Clinicians perceive parental issues as the most common impediments to these discussions. Furthermore, providers believe that advance care discussions happen too late in the course of illness. (Read the full article)




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Misclassification of Newborns Due to Systematic Error in Plotting Birth Weight Percentile Values

Percentile charts for birth weight are used to assess the somatic development of neonates (small, appropriate, or large for gestational age).

A systematic error was identified in the majority of birth weight percentile charts. As a consequence, small for gestational age rates are overestimated and large for gestational age rates are underestimated; ~5% of neonates are misclassified. (Read the full article)




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Growth and Fat-Free Mass Gain in Preterm Infants After Discharge: A Randomized Controlled Trial

Postnatal growth restriction of preterm infants is a universal problem. Early "catch-up growth" has been associated with development of metabolic syndrome. In addition, preterm infants appear to be at major risk for developing increased adiposity and insulin resistance.

The consumption of a nutrient-enriched formula after hospital discharge may be beneficial in adequate for gestational age infants both in terms of head circumference growth and fat-free mass gain. (Read the full article)




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In Utero Exposure to Ischemic-Hypoxic Conditions and Attention-Deficit/Hyperactivity Disorder

Although previous studies indicate that perinatal factors are associated with altered neurodevelopment, data on the association between ischemic-hypoxic conditions and attention-deficit/hyperactivity disorder in children are sparse.

This study demonstrates that preeclampsia, birth asphyxia, and respiratory distress syndrome are independently associated with increased risk of attention-deficit/hyperactivity disorder in a large population-based study. (Read the full article)




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Discharge Timing, Outpatient Follow-up, and Home Care of Late-Preterm and Early-Term Infants

Infants born late-preterm and early-term are at higher risk of morbidity and mortality compared with term infants. Home care practices recommended for all infants include supine sleep position, no smoke exposure, and breastfeeding to optimize health outcomes.

Our study provides new findings on the timing of hospital discharge, outpatient follow-up, and home care of late-preterm and early-term infants compared with term infants in the United States. (Read the full article)




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Rotavirus Vaccination of Very Low Birth Weight Infants at Discharge From the NICU

Preterm and low birth weight infants are at increased risk of hospitalization due to rotavirus gastroenteritis, and rotavirus vaccine is immunogenic and well tolerated among these infants when provided at or after discharge from the NICU.

Many preterm infants with a birth weight of ≤1500 g are not eligible to receive rotavirus vaccination because they remain in the NICU beyond the upper age limit recommended for immunization. New strategies are needed. (Read the full article)




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Antepartum and Intrapartum Factors Preceding Neonatal Hypoxic-Ischemic Encephalopathy

Etiology and timing of onset of neonatal hypoxic-ischemic encephalopathy continue to be controversial. Previous studies suggest antepartum events are the main contributing factors, but have used a broad definition of encephalopathy and included infants with genetic, congenital, and developmental abnormalities.

Our study suggests that when strict criteria defining hypoxic-ischemic encephalopathy are applied with supporting neuroimaging evidence of an acute hypoxic-ischemic insult, intrapartum events are the final and necessary pathway leading to this condition. (Read the full article)




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The Architecture of Provider-Parent Vaccine Discussions at Health Supervision Visits

An increasing number of parents have concerns about childhood vaccines. Parents consistently cite their child’s provider as influential in their vaccine decision-making. Little is known about how providers communicate with parents about vaccines and which communication strategies are important.

How providers initiate the vaccine recommendation at health supervision visits appears to be an important determinant of parent resistance. Also, when providers pursue their original vaccine recommendations in the face of parental resistance, many parents subsequently agree to vaccination. (Read the full article)




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Indiscriminate Behaviors in Previously Institutionalized Young Children

Children who have experienced early psychosocial deprivation are at high risk of persistent, socially indiscriminate behaviors. These behaviors may decline slowly with high-quality caregiving but generally are associated with ongoing impairment.

This study suggests that placement in foster care reduces indiscriminate behaviors to an intermediate level between those in institutional care and community control subjects. It also demonstrates the importance of disorganized early attachment in predicting later indiscriminate behaviors. (Read the full article)




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A Randomized Trial on Screening for Social Determinants of Health: the iScreen Study

Despite growing interest around clinical screening for health-related social and environmental risk factors, little evidence exists regarding screening formats that maximize disclosure of psychosocial information.

This study compares psychosocial and socioeconomic adversity disclosure rates in face-to-face interviews versus electronic formats in a large, urban pediatric emergency department. (Read the full article)




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Early Discharge of Infants and Risk of Readmission for Jaundice

Studies examining early postnatal discharge and readmission for jaundice report conflicting results. Infants born 37 to 38 weeks’ gestation have an increased risk for readmission for jaundice; however, the impact of early discharge on this group has not been investigated.

Early postnatal discharge was significantly associated with readmission for jaundice. Of the infants discharged early, those born 37 to 38 weeks’ gestation, born via vaginal delivery, born to Asian mothers, or were breastfed had the greatest risk for readmission. (Read the full article)




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Discrepancies Between Transcutaneous and Serum Bilirubin Measurements

In most previous studies, transcutaneous bilirubin measurement has been found to provide an accurate estimate of total serum bilirubin levels. However, most of these studies were conducted in settings that optimized accuracy.

This study provides a "real-world" assessment of the accuracy of transcutaneous bilirubin measurements in multiple clinical settings and identification of sources of discrepancy between transcutaneous and total serum bilirubin measurements. (Read the full article)




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Incidence and Outcomes of Symptomatic Neonatal Arterial Ischemic Stroke

Neonatal arterial ischemic stroke is associated with later cerebral palsy and cognitive impairment. Many studies on neonatal ischemic stroke are limited by modest sample sizes, and prospective studies that include outcomes assessments are scarce.

Results from this prospective, nationwide, population-based study provide information on the epidemiology, associated clinical variables, clinical manifestation, vascular distribution, and treatment of neonatal arterial ischemic stroke. The study also provides outcomes regarding motor function and cognition. (Read the full article)




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Prevalence of Parental Misconceptions About Antibiotic Use

Attitudes and knowledge about appropriate management of common childhood illnesses may lead parents to mistakenly believe antibiotics are needed. Differences existed in antibiotic knowledge and attitudes between parents of Medicaid- and commercially insured children and according to other sociodemographic variables.

Despite efforts to decrease unnecessary antibiotic use, misconceptions about antibiotic use persist and continue to be more prevalent among parents of Medicaid-insured children. Tailored efforts for socioeconomically disadvantaged populations remain warranted to decrease parental drivers of unnecessary antibiotic prescribing. (Read the full article)




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Predicting Discharge Dates From the NICU Using Progress Note Data

Discharge from the NICU requires coordination and may be delayed for nonmedical reasons. Predicting when patients will be medically ready for discharge can avoid these delays and result in cost savings for the hospital.

We developed a supervised machine learning approach using real-time patient data from the daily neonatology progress note to predict when patients will be medically ready for discharge. (Read the full article)




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Treating EEG Seizures in Hypoxic Ischemic Encephalopathy: A Randomized Controlled Trial

Continuous conventional EEG video is currently gold standard for identifying neonatal seizures and a substantial proportion of neonatal seizures are electrographic. Currently there is no direct evidence that EEG monitoring, seizure identification, or treatment impacts long-term outcomes.

In neonates with hypoxic ischemic encephalopathy, EEG monitoring and treatment of electrographic seizures results in significant reduction in seizure burden. Increasing seizure burden is associated with more severe brain injury and significantly lower performance scores on Bayley Scales of Infant Development III. (Read the full article)




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Researchers explore quantum computing to discover possible COVID-19 treatments

Quantum machine learning, an emerging field that combines machine learning and quantum physics, is the focus of research to discover possible treatments for COVID-19, according to Penn State researchers, who believe that this method could be faster and more economical than the current methods used for drug discovery.




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Explore, discover and define your future at March 28 open house

From 9 a.m. to 3 p.m. Saturday, March 28, members of the Penn College community will welcome thousands of potential enrollees and their families, opening wide the doors to a landmark institution that has helped tomorrow makers fulfill their destinies for more than a century.




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Penn College offers discounted Building Operator Certification courses

The National Sustainable Structures Center of Pennsylvania College of Technology, the mid-Atlantic administrator of the Building Operator Certification, will offer two BOC Level I courses at a 75% discount made possible by a grant from the Pennsylvania Department of Environmental Protection.




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Penn State and Palmer Museum mourn death of donor and alumnus John Driscoll

Penn State and the Palmer Museum of Art mourn the loss of dear friend, generous donor, and loyal champion John P. Driscoll, who died from complications due to COVID-19 on Friday, April 10. Driscoll, owner of Driscoll Babcock Galleries in New York, was a longtime friend and supporter of the Palmer Museum and will be remembered for his role as a leader, gracious mentor and trusted adviser, as well as for the expansive gifts he made to the collection and to his alma mater, Penn State.




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Stuckeman School studio breaks down disciplinary lines through design

A studio course for architecture and landscape architecture students in the Stuckeman School prepares students for the collaborative design process they will take part in once they begin careers in their respective fields by blurring the boundaries between the disciplines in the college setting.




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Seed grants jump-start 47 interdisciplinary teams to conduct COVID-19 research

With speed and ingenuity, more than 100 researchers across Penn State are shifting their research programs to address the COVID-19 crisis, thanks to funding from a seed grant initiative led by the Huck Institutes of the Life Sciences. In total, the initiative awarded $2.25 million to 47 teams of researchers from three campuses, 10 colleges and more than 25 departments.




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COVID-19 response at Penn State propelled by interdisciplinary connections

MASC has successfully designed and delivered critical equipment and supplies needed to protect health care workers and patients during the COVID-19 pandemic.




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Predictive Ability of a Predischarge Hour-specific Serum Bilirubin for Subsequent Significant Hyperbilirubinemia in Healthy Term and Near-term Newborns

Vinod K. Bhutani
Jan 1, 1999; 103:6-14
ARTICLES




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The EPICure Study: Outcomes to Discharge From Hospital for Infants Born at the Threshold of Viability

Kate Costeloe
Oct 1, 2000; 106:659-671
ARTICLES




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Teacher Incentive Fund Awards Its Last Grants for Fiscal Year

Another dozen school districts have landed federal Teacher Incentive Fund grants, including one that will focus on paying principals and assistant principals for their performance.




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Discussing Blended Learning and Remote Learning

We talk a lot about blended learning opportunities in my district, asking ourselves whether we are offering the most beneficial learning opportunities for both staff and students. We're looking to provide quality online learning resources to students when they are outside of our classrooms, as well




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Barron discusses Penn State’s response to pandemic and actions for trustees

As the world continues to face the ongoing impacts of the global coronavirus pandemic, Penn State President Eric Barron outlined Friday the University’s actions over the past five months to address the challenges, protect the health and safety of the University community, and prepare for the future.




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Few Science Textbooks Show How New Discoveries Are Really Made

A new study finds that materials often portray scientists as geniuses working alone—a framing that can make students think science isn't for them.




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Brandywine, Tyler Arboretum offer online discussion group during pandemic

Penn State Brandywine’s Sustainovation Team has partnered with Tyler Arboretum to host an online discussion club for podcasts, offering a creative solution for the local community to stay connected during the coronavirus (COVID-19) pandemic.




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Schuylkill Speaks: Senior Dominique Varra discovers enthusiasm for ornithology

When she began the biology program at Penn State Schuylkill, senior Dominique Varra thought she wanted to study plants. But after conducting field research studying gray catbirds with Luke Redmond, assistant professor of biology, she has discovered a passion for ornithology. And all of her accomplishments have inspired the next generation of scientists, chiefly her five-year-old daughter Hayden, who hopes to follow in her mother’s footsteps.




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Penn State Law to host panel discussion on current Supreme Court term

Penn State Law in University Park will host "A Take on the Term" with Sarah Harrington and Erin Murphy, beginning at 4:30 p.m. Thursday, March 5, in the Sutliff Auditorium of the Lewis Katz Building.




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Cisco Secures Injunction Against Chinese Counterfeiters

The injunction means all major online retailers—including Amazon and eBay—can no longer sell Cisco-branded products offered by four Chinese companies.




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Stronger disciplinary regulations approved

030 - Venues for finals of UEFA 2015 club competitions chosen




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How San Francisco Is Transforming Science Education

A partnership works to create and implement a district-wide NGSS-aligned science curriculum and instructional model.




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Wisconsin Lawmakers Create Task Force to Help Rural Schools

Wisconsin lawmakers have established a new rural school task force to figure out how to address challenges such as declining enrollment and increasing transportation costs.




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Rural Schools Often Ignored in Research and Policy Discussions

Rural schools struggle with high and lows more commonly associated with urban schools, including high rates of poverty, low literacy rates, and low college attendance rates, a new report finds.




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Fin24.com | WATCH: #BlackFriday discounts are real, but beware of FOMO

Ahead of the Black Friday sale, Fin24 presenter Moeshfieka Botha talks to Vincent Hoogduijn, the CEO of e-commerce at Media 24, about discounts, spending your money wisely and Black Friday FOMO.




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Fin24.com | Central banks must be careful not to get sucked into fiscal policy - Kganyago

The economic meltdown has seen the world's leading central bankers including the South African Reserve Bank come under pressure to bail out their respective economies in the form of interest rate cuts. They've been urged to fund governments, an idea that central bank governor, Lesetja Kganyago, says is tantamount to a client instructing their banker to do the same.




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Pisces Horoscope for May 9, 2020

Your swift action will solve your longstanding problem. Today, seek the blessings of your elders before going out of the house, as it will benefit you. Joyful time with family and friends Erratic behaviour of your darling might make your mood upset. Travel undertaken for business purpose will prove to be beneficial in the long run. You might feel annoyed by your spouse due to off mood. Today, you can feel good by helping a friend.




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2012 Conference On Housing Hosted By DSHA And Governor Jack Markell: A Successful Discussion On All Things Housing

Delaware State Housing Authority (DSHA) along with Governor Markell and their partners today held the 2012 Governor’s Conference on Housing. The event brought together over 400 housing professionals and residents from throughout Delaware and surrounding states to discuss important issues in housing ranging from homeownership, affordable rental housing, special needs populations and other hot topics. Attendees had the opportunity to discuss regional, state and local perspectives on today’s affordable housing climate, and the event provided strategies to address current and future housing needs.




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Visits to campus landmarks discouraged; Lion Shrine to close for maintenance

University officials, who have discouraged visits to campus and campus landmarks due to COVID-19, are increasing signage and social distancing guidance around the sites, as visitors continue to seek photographs in those areas and appear to be ignoring health care recommendations.




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New Magazine Seeks to Bring 'Civil Discourse' to Education Debate

Headed up by former Los Angeles superintendent John E. Deasy, The Line will feature a variety of viewpoints on major K-12 issues.




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Discovering Jesus

Through community development projects, workers in Central Asia meet people interested in Jesus.




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Discipleship on a daily basis

God uses OMers to show His love to local believers, who then spread that love to their own communities.




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Black-White Achievement Gaps Go Hand in Hand With Discipline Disparities

As black-white achievement gaps widen in schools, so, too, do disparities in discipline rates between black and white students, according to a study published Wednesday of 2,000 schools.




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There's a Disconnect Between Parent Expectations and Student Realities

A first look at new federal data on parent involvement suggests a disconnect between parents' expectations and school outcomes.




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Deadline Approaches for Delaware Unclaimed Property Voluntary Disclosure Agreement

The clock is ticking for Delaware companies that may wish to convert their abandoned and unclaimed property audits to a Voluntary Disclosure Agreement offered by the Secretary of State. Eligible firms have until Dec. 11, 2017 to choose a VDA conversion.




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WEDNESDAY: Governor Carney Hosting Discussions on Arts, Historic Preservation

WILMINGTON, Del. – On Wednesday, November 1, Governor John Carney will host roundtable discussions with leaders in Delaware’s arts & culture, and historic preservation communities. The discussions are part of Governor Carney’s efforts to showcase Delaware as an attractive home for businesses and their employees. Follow Governor Carney’s discussions using the hashtag #OptionsInDE, and learn […]



  • Department of State
  • Governor John Carney
  • Office of the Governor