The present invention is directed to processes for recovering ethanol obtained from the hydrogenation of acetic acid. Acetic acid is hydrogenated in the presence of a catalyst in a hydrogenation reactor to form a crude ethanol product. The crude ethanol product is separated in one or more columns to recover ethanol. In some embodiments, less than 10 wt. % ethanol is recycled to the hydrogenation reactor.

A method for producing a phenylphosphonic acid metal salt composition, including reacting a phenylphosphonic acid compound (a) with a metal salt, metal oxide or metal hydroxide (b) that is present in an amount beyond the equivalent, the phenylphosphonic acid metal salt composition containing phenylphosphonic acid metal salt, and a surplus amount of the metal salt, the metal oxide or the surplus metal hydroxide (b). A crystal nucleating agent comprises the phenylphosphonic acid metal salt composition produced by the method.

A system for controlling a plurality of vehicles can include at least one communications bus and a plurality of RFID detection tags that can be fixed to the communications bus equidistant from each other to define a plurality of RFID regions. Each vehicle within an RFID region can further include an RFID reader for receiving information from, and transmitting information to, the RFID tags. As the vehicle enters the RFID region for a particular RFID tag, the position of the vehicle (within the RFID region) can be communicated to the communications bus. A traffic control unit can be connected to the communications bus, and monitor can be in communication with a plurality of remotely controlled traffic control assets, such as stop signs, yield signs, traffic cones. After receiving position information on the vehicle, the monitor can selectively activate the traffic devices remotely to control vehicle traffic flow.

Disclosed is a feature for a vehicle that enables taking precautionary actions in response to conditions on the road network around or ahead of the vehicle, in particular, a blind intersection along a section of road. A database that represents the road network is used to determine locations where a blind intersection is located along a section of road. Then, precautionary action data is added to the database to indicate a location at which a precautionary action is to be taken about the blind intersection located along the section of road. A precautionary action system installed in a vehicle uses this database, or a database derived therefrom, in combination with a positioning system to determine when the vehicle is at a location that corresponds to the location of a precautionary action. When the vehicle is at such a location, a precautionary action is taken by a vehicle system as the vehicle is approaching a blind intersection.

A method of adjusting a speed of a mobile machine is provided. Image data of a location is collected where currently generated sensor data and previously generated sensor data indicate a discontinuity in sensor data. The image data is analyzed to determine if a non-motion blur score for the image data is above a threshold value. Then, a speed of the mobile machine is adjusted based on a determination that the non-motion blur score is above the threshold value.

An apparatus for estimating a travel path of a vehicle is mounted on the vehicle; and includes: an object detection device that detects an object lying ahead of the vehicle; a stationary object detection device that determines whether a detected object is a stationary object; a device that calculates an approximate straight line indicating a path of the stationary object from the temporal positional data for the stationary object projected on two-dimensional coordinates using a vehicle position as a starting point; a device that calculates a orthogonal line which passes through a midpoint in the temporal positional data for the stationary object and goes straight with respect to the approximate straight line on the two-dimensional coordinates; and a device that calculates a vehicle turning radius from an intersection point where the orthogonal line intersects with a x axis.

The invention relates to compressed data transmission in wireless data communication. Disclosed are methods and apparatuses for transporting residue of vehicle position data via a wireless network. A disclosed method for transporting residue of vehicle position data via a wireless network, includes the steps of: receiving data for updating residue encoding schema from a monitoring server; constructing a residue encoding schema based on the data, thereby producing a constructed residue encoding schema; and storing the constructed residue encoding schema such that the constructed residue encoding schema will become the current residue encoding schema; where: the constructed residue encoding schema is constructed such that each residue of the constructed residue encoding schema corresponds to a code; and the constructed residue encoding schema is constructed such that a residue having a relatively high probability of occurrence corresponds to a code of relatively short length.

A vehicle control device capable of more appropriately carrying out travel control of an own vehicle carried out while acquiring travel information of a leading vehicle by an inter-vehicle communication is provided. Provided is a vehicle control device for carrying out vehicle control of acquiring inter-vehicle communication information of a leading vehicle travelling in front of an own vehicle, and controlling a travel state of the own vehicle based on the acquired inter-vehicle communication information of the leading vehicle, wherein control of the inter-vehicle communication is changed according to a parameter at the time of the vehicle control.

A vehicle travel control device can accurately determine a driver's intention to adjust the vehicle speed. After applying attention attracting reaction force corresponding to outside circumstances and the like to an accelerator pedal through a reaction force application mechanism, a reaction force control unit outputs intention determining reaction force that is used to determine the driver's intention to adjust the vehicle speed and is smaller than the attention attracting reaction force, and determines the intention to adjust the vehicle speed on the basis of the accelerator pedal operation amount of the driver while the intention determining reaction force is being applied to the accelerator pedal through the reaction force application mechanism.

The present invention relates to a control system and a method for a hybrid vehicle which may optimally control the operating point of a vehicle. A control method for a hybrid vehicle includes detecting driving requests and a state of charge (SOC) of a battery when the vehicle is driving in HEV mode, determining a motor operating point and an engine operating point when the battery is in low SOC state, and compensating the motor operating point and the engine operating point by applying a climbing degree of the vehicle and the atmospheric pressure.

In an electric powered vehicle in which vehicle driving force for reverse running is produced by a traction motor, vehicle driving force is set by a product of a base value set at least based on an accelerator opening and an amplification factor. The amplification factor is set at k1=1.0 during reverse running (V1.0 at the start of reverse running (V≧0) depending on the vehicular speed. The vehicle driving force at the start of reverse running can thereby be made larger than the vehicle driving force after the start of reverse running at the same accelerator opening.

Disclosed is a vehicle control apparatus which can prevent the deterioration of drivability. The ECU can set a control accelerator opening degree to be converted when a control permission condition is established. The control accelerator opening degree is equal to or larger than an accelerator lower limit which is larger than an idle determination value for determining an automatic stopping of an engine by an eco-run. The control accelerator opening degree thus set can prevent the drivability from being deteriorated without the automatic stopping of the engine being caused even if the accelerator opening degree is converted to reduce the torque of the engine with the establishment of the control permission condition.

A method of monitoring an engine coolant system includes modeling the total energy stored within an engine coolant. If an actual temperature of the engine coolant is below a minimum target temperature, the modeled total energy stored within the energy coolant is compared to a maximum stored energy limit to determine if sufficient energy exists within the engine coolant to heat the engine coolant to a temperature equal to or greater than the minimum target temperature. The engine coolant system fails the diagnostic check when the modeled total energy stored within the energy coolant is greater than the maximum stored energy limit, and the minimum target temperature has not been reached.

A vehicle notification sound emitting apparatus is basically provided with a first sound emitting device, a second sound emitting device and a notification sound control device. The first sound emitting device emits a first intermittent notification sound inside a cabin interior of a vehicle. The second sound emitting device emits a second intermittent notification sound outside of the cabin interior of the vehicle. The notification sound control device operates the first and second sound emitting devices to separately emit the first and second intermittent notification sounds in at least a partially overlapping pattern in response to occurrence of a vehicle condition to convey a same type of vehicle information to both inside and outside of the cabin interior of the vehicle. The notification sound control device includes a cabin interior-exterior notification sound synchronizing section that is configured to synchronize the first and second intermittent notification sounds.

A control device for a hybrid vehicle includes a portion determining whether an engine torque is necessary, a portion controlling a motor to make a motor torque be a target torque, an engine rotation speed control portion controlling an engine output shaft to rotate at a target engine rotation speed for sudden start/reacceleration while the clutch being disengaged after starting the engine and before an actual rotation speed of the engine output shaft exceeds a reference target engine rotation speed in a case where the engine torque is necessary, a control portion engaging the clutch after the actual rotation speed exceeds the reference target engine rotation speed, and a portion controlling the engine so that the engine torque is assumed to be a target torque by canceling the control by the engine rotation speed control portion after the actual rotation speed exceeds the reference target engine rotation speed.

Vehicle event recorder systems are arranged to be in constant communication with remote servers and administrators via mobile wireless cellular networks. Vehicle event recorders equipped with video cameras capture video and other data records of important events relating to vehicle use. These data are then transmitted over special communications networks having very high coverage space but limited bandwidth. A vehicle may be operated over very large region while maintaining continuous communications connections with a remote fixed server. As such, systems of these inventions may be characterized as including a mobile unit having: a video camera; a microprocessor; memory; an event trigger; and mobile wireless transceivers, and a fixed network portion including: mobile wireless cellular network, a protocol translation gateway, the Internet and an application-specific server.

A traction control system in vehicle comprises a detector for detecting a monitored value which changes according to a degree of a drive wheel slip; a condition determiner for determining whether or not the monitored value meets a control start condition and whether or not the monitored value meets a control termination condition; and a controller for executing traction control to reduce a driving power of the drive wheel during a period of time from when the condition determiner determines that the monitored value meets the control start condition until the condition determiner determines that the monitored value meets the control termination condition; the condition determiner being configured to set at least the control start condition variably based on a slip determination factor which changes according to a vehicle state and such that the control start condition changes more greatly according to the vehicle state than the control termination condition.

In a method for fracturing or mask data preparation or mask process correction for charged particle beam lithography, a plurality of shots are determined that will form a pattern on a surface, where shots are determined so as to reduce sensitivity of the resulting pattern to changes in beam blur (βf). In some embodiments, the sensitivity to changes in βf is reduced by varying the charged particle surface dosage for a portion of the pattern. Methods for forming patterns on a surface, and for manufacturing an integrated circuit are also disclosed, in which pattern sensitivity to changes in βf is reduced.

A method for mask data preparation or mask process correction is disclosed in which a set of charged particle beam shots is determined which is capable of forming a pattern on a surface, wherein critical dimension uniformity (CDU) of the pattern is optimized. In some embodiments the CDU is optimized by varying at least two factors. In other embodiments, model-based techniques are used. In yet other embodiments, the surface is a reticle to be used in an optical lithographic process to form a pattern on a wafer, and CDU on the wafer is optimized.

Some example embodiments include a computer-implemented method for designing an integrated circuit. The computer-implemented method includes receiving a hierarchical network design for the integrated circuit, wherein the hierarchical design comprises a number of components that are coupled together. The computer-implemented method includes detecting that a component of the number of components has at least one of failed timing and incomplete timing based on a problem that comprises at least one of a missing assertion, one or more missing latches, a source driver having an input source slew that is greater than a source slew limit threshold, and a sink having an input sink slew that is greater than a sink slew limit threshold. The computer-implemented method includes replacing the component with a different component that is independent of the problem and testing others components of the number of components based on the different component.

A method and system for optical proximity correction (OPC) is disclosed in which a set of shaped beam shots is determined which, when used in a shaped beam charged particle beam writer, will form a pattern on a reticle, where some of the shots overlap, where the pattern on the reticle is an OPC-corrected version of an input pattern, and where the sensitivity of the pattern on the reticle to manufacturing variation is reduced. A method for fracturing or mask data preparation is also disclosed.

Disclosed are methods, systems, and articles of manufactures for implementing physical designs by using multiple force models to iteratively morph a layout decomposition. In addition to attractive force model(s) or repulsive force model(s), the physical implementation also uses a containment force model for grouping multiple design blocks or for confining a node of a cell within the boundary of a container. Another aspect is directed at deriving a first force model at the first hierarchical level from a second force model at the second hierarchical level by directly modifying the second model based at least in part on characteristic(s) of the first hierarchical level and of the second hierarchical level. In a design with multiple hierarchies, a cell-based force model is also used to ensure child nodes of a parent cell stay within a close proximity of the parent node of the parent cell.

A cleaning composition for sanitizing and/or disinfecting hard surfaces, comprising: a cationic biocide, surfactant and low levels of VOC solvents. The cleaning composition is adapted to clean a variety of hard surfaces without leaving behind a visible residue and creates low levels of streaking and filming on the treated surface. The cleaning composition contains less than 5% by weight of VOCs. The cleaning composition may be used alone as a liquid or spray formulation or in combination with a substrate, for example, a pre-loaded cleaning wipe.

Provided is an aqueous cleaning composition comprising at least one surfactant, xanthan gum, and a carbonate salt, wherein the composition has a turbidity of less than 16 NTU. Also provided is a method of cleaning a substrate by applying the cleaning composition to the substrate.

Disclosed is a cleansing composition containing from about 6% to about 20% of at least one nonionic surfactant; from about 3% to about 10% of at least one amphoteric surfactant; from about 2% to about 8% of at least one anionic surfactant; and from about 0.1% to about 5% of at least one cationic conditioning surfactant, cationic conditioning amine, or a mixture thereof; wherein the amount of nonionic surfactant present in the final composition is greater than the amount of the amphoteric surfactant, and the ratio of the nonionic surfactant (a) to anionic surfactant (c) is at least about 1.9 as much as the anionic surfactant, based on the weight percent of each surfactant in the final composition.

Liquid compositions for cleaning, in particular medical instruments and air conditioning surfaces, said composition excluding surfactants and comprising one or more enzymes including a protease and optionally a hydrolase, a solvent system including a water soluble glycol ether solvent, at least one anionic hydrotrope, and wherein the molar ratio of said at least one hydrotrope to said glycol ether in the composition is selected to preserve the activity of said one or more enzymes. The hydrotrope is advantageously an anionic hydrotrope selected from the group consisting of water soluble anionic hydrotropes of the formula (I) and having no alkyl side chain greater than six carbons in length, for example a xylene sulfonate or cumene sulfonate salt.

A process for preparing a particle defoamer. The particle defoamer of 55%-75% of a carrier, 15%-35% of a silicone emulsion, 3%-10% of a texturing agent and 2%-10% of a solvent, based on the total weight of the particle defoamer; the process for preparing the particle defoamer is: (1)first adding a carrier A1 into a mixer, and then adding thereto a silicone emulsion B1, and stirring uniformly; (2)adding a carrier component A2 to the mixture obtained in (1), and stirring uniformly; (3)adding a silicone emulsion B2 to the mixture obtained in (2), and, after uniformly stirring, adding the solvent thereto and stirring uniformly; and (4)pelleting and drying by baking the mixture obtained in(3), so as to produce the product.

The invention describes a stable liquid washing agent or liquid cleaning agent having a yield point and very good dispersing properties. The agents contain anionic and nonionic surfactants as well as inorganic salt and cosurfactant. The invention also relates to the use of the liquid washing agent or liquid cleaning agent, and to a method for manufacturing it.

A chemical composition for cleaning a medium is provided. For some embodiments, the chemical composition comprises a nonionic surfactant, an inorganic salt, a glycol compound, a chelating agent, and deionized water. For example, the chemical composition may comprise between about 1% and 5% of nonionic surfactant, between about 2% and 6% by weight of an inorganic salt, between about 5% and 10% by weight of a glycol compound, between about 5% and 10% by weight of a chelating agent, and deionized water.

Compositions and methods for improved cleaning using neutral cleaners are disclosed. In particular, neutral pH cleaning compositions according to the invention employ a synergistic combination of water insoluble surfactants and an anionic hydrotropes capable of forming a stable, low-foaming solution. The neutral cleaning solutions provide significant benefits over water insoluble microemulsions traditionally used for neutral cleaning compositions and provide at least equivalent cleaning efficacy as non-neutral cleaning compositions.

The present invention relates to an enzyme composition comprising enzyme containing polymer particles, which is useful for detergent compositions, in particular for liquid detergent compositions. In these enzyme containing particles, the particles comprise i) at least one enzyme, and ii) at least one polymer P, which is selected from homo- and copolymers having a C—C-backbone, wherein the C—C-backbone carries carboxylgroups, which may be present in the acidic form or in the neutralized form, and wherein the C—C-backbone comprises hydrophobic repeating units.

A non-aqueous liquid cleaning composition for applicators used for applying non-aqueous hair removal compositions to the skin. The composition includes a solubilizing oil effective for solubilizing the non-aqueous hair removal composition, e.g., mineral oil, and an effective antibacterial amount of an antibacterial agent, e.g., triclosan. The composition may also include fragrances and additional bacteriocides, e.g., phenoxyethanol. When the applicator is contacted with the heated cleaning composition any hair removal composition and bacteria on the applicator are removed therefrom and the applicator is ready for reuse. It is preferred to use surgical stainless steel applicators. Also provided are methods of using these compositions and kits containing, among other items, such compositions and applicators.

Acidic viscoelastic cleaning compositions are disclosed which use non polymer thickening agents. According to the invention, cleaning compositions have been developed using viscoelastic surfactants in acidic cleaning formulations. These provide the dual benefit of thickening as well as an additional cleaning, thereby improving performance. Applicants have also identified several pseudo linking agents which when, used with viscoelastic surfactants provide enhanced viscoelasticity and cleaning.

A cleansing composition for cleansing skin, especially for removing grease from skin. A cleaning composition of the present invention may also be used in ready-to-use (or in-use) kits, such as two component kits, suitable for cleansing skin.

The present invention relates to a skin cleanser composition capable of providing an excellent frictional resistance feeling during rinsing and capable of giving an excellent silky feeling with moisturization to the skin after drying, and to a method for producing the composition. The skin cleanser composition contains a cat ionized hydroxypropyl cellulose (A) and a surfactant (B), and the cationized hydroxypropyl cellulose (A) has an anhydroglucose-derived main chain, and has a degree of substitution with cationized ethyleneoxy group of from 0.01 to 3.0 and a degree of substitution with propyleneoxy group of from 0.01 to 2.9.

Alkyl nitrate ester compounds are provided for the delivery of nitric oxide to targeted muscle tissues, and in particular, to normal and dystrophic muscles. In one aspect, nitrate ester compounds are provided having the following formula: wherein, R1 is ONO2, CH2ONO2, CnH2n+1OH, CnH2n+1OH, or CH2CH2CH3, or H;R2 is ONO2, CH2ONO2, Cn'H2n'+1OH, Cn'H2n'+1OH, CH2CH2CH3 or H; andR3 is ONO2, CH2ONO2, Cn'″H2n″+1OH, Cn″H2n″+1OH, CH2CH2CH3 or H; wherein n is an integer from 0 to 9, n' is an integer from 0 to 9, and n″ is an integer from 0 to 9, and n+n'+n″≦9, and wherein at least one of R1, R2, and R3 is an ester nitrate selected from the group consisting of ONO2, CH2ONO2, and combinations thereof.

In V2V or other networks in which multiple video cameras can share video data, a network participant ordinarily has the option of selecting a particular video data stream (either generated by local cameras or received from other network participants. To facilitate the process of selecting a video data stream for presentation, the user's vehicle (in a V2V network) receives video data streams generated by other network participants along with identifiers indicating the video data stream actually being presented to the sender. The receiving system identifies the received video data stream by the greatest number of network participants and displays the identified video data stream on the user's in-vehicle video display.

A vehicle communication method comprises receiving a first wireless communication that is transmitted from a first remote device and managing a transmission of the first wireless communication over a vehicle network using a configurable message list. The receiving a first wireless communication is performed by a connectivity device coupled to a communication port of the vehicle network. The managing a transmission of the first wireless communication is performed by a message manager module of the connectivity device.

A method for detecting and conveying an alarm signal, when an absorbent article is unfastened or, completely removed from the body of the wearer. The method is intended to be used in parallel with a method for detecting wetness in the absorbent article and further relates to an integrated detection-and-alarm method for detecting unfastening and/or wetness in an absorbent article. A system for detecting and conveying an alarm signal when an absorbent article is unfastened or removed from the body of the wearer and/or when the article is wet. The system includes (a) and absorbent article having at least one absorbent layer, the object to be displaced, such as a fastening system, one or more sensoring devices, one or more transmitting devices, and (b) a remote receiver. Furthermore, the system relates to the use of the system in the care of children and adults suffering from incontinence and/or psychological illnesses.

Disclosed is a process for the production and purification of glycolic acid or glycolic acid derivatives by the carbonylation of aqueous formaldehyde. The water in the hydrocarboxylation zone is reduced via reaction with the ester bonds in a recycle stream comprising glycolic acid oligomers and/or methyl glycolate oligomers.

The present invention concerns a TCTP antagonist, in particular a nucleic acid targeting an m RNA encoding Translationally-Controlled Tumor Protein (TCTP), wherein said nucleic acid is capable of reducing the amount of TCTP in cells, for use in the treatment or prevention of hormone-independent cancer or chemo-resistant cancer, such as an androgen-independent prostate cancer.

The invention describes new structures of the nucleotide conjugates (nuc-macromolecules) comprising at lease one nucleotide moiety coupled to at least one macromolecular compound via a short linker. These conjugates can be used as substrates for various kinds of polymerizing enzymes in the enzymatic synthesis of nucleic acids. In particular, these compounds can be used for labeling nucleic acids.

The present invention is related to an L nucleic acid that binds to an SDF-1.

An antisense molecule capable of binding to a selected target site to induce exon skipping in the dystrophin gene, as set forth in SEQ ID NO: 1 to 202.

This invention relates to a process for preparing an oligonucleotide 5'-triphosphate. The process comprises the steps of: (a) synthesizing an oligonucleotide having a 5' hydroxyl moiety; (b) reacting the 5' hydroxyl moiety with a reagent of formula I: to convert the 5' hydroxyl moiety to a 5'-H-phosphonate, wherein R1 and R2 are each independently selected from the group consisting of haloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, cycloalkyl, substituted cycloalkyl, heterocycle, and substituted heterocycle, acyl, phosphoryl, substituted alkyl acyl, substituted heteroalkyl acyl, substituted aryl acyl or substituted heteroaryl acyl, substituted alkyl phosphoryl, substituted heteroalkyl acyl, substituted aryl phosphoryl, and substituted heteroaryl phosphoryl; (c) activating the H-phosphonate of step (b) by reacting the H-phosphonate with a silylating agent, a halogenated oxidizing agent, a nitrogen-containing heteroaryl, or a combination thereof, to form an activated H-phosphonate; and (d) treating the oligonucleotide having an activated H-phosphonate from step (c) with a poly(alkylammonium)pyrophosphate.

The invention refers to polynucleotides selected from the group consisting of a) polynucleotides encoding for the polypeptide RBM20 comprising a P638L mutation for a human polypeptide RBM20, or a P641L mutation for a rat polypeptide RBM20, b) polynucleotides with a reverse complementary sequence of the polynucleotide of a) above, and c) polynucleotides with an identity at least 50% to a polynucleotide of a) or b) above.

The present disclosure provides reagents that can be used to label synthetic oligonucleotides with rhodamine dyes or dye networks that contain rhodamine dyes.

The present disclosure generally relates to dry solid matrices for the extraction, stabilization, and storage of nucleic acids, particularly RNA, in a dry format under ambient conditions for a prolonged period of time. Methods for collecting and recovering the nucleic acids stored in the dry solid matrix are also described.

A solid matrix for the extraction, stabilization, and storage of nucleic acids is provided. At least one protein denaturant, and at least one acid or acid-titrated buffer reagent are impregnated in a dry state therein the matrix; and the matrix is configured to provide an acidic pH on hydration. The matrix is configured to extract nucleic acids from a sample and stabilize the extracted nucleic acids, particularly RNA, in a dry format under ambient conditions for a prolonged period of time. Methods for collecting and recovering the nucleic acids stored in the dry solid matrix are also described.

The present disclosure generally relates to solid matrices for the extraction, stabilization, and storage of nucleic acids, particularly RNA, in a dry format under ambient conditions for a prolonged period of time. Methods for extracting, collecting, and recovering nucleic acids from the solid compositions are also described.