ni High frequency synchronizer By www.freepatentsonline.com Published On :: Tue, 28 Apr 2015 08:00:00 EDT Techniques for resolving a metastable state in a synchronizer are described herein. In one embodiment, a circuit for resolving a metastable state in a synchronizer comprises a signal delay circuit coupled to a node of the synchronizer, wherein the signal delay circuit is configured to delay a data signal at the node to produce a delayed data signal, and a transmission circuit coupled to the signal delay circuit, wherein the transmission circuit is configured to couple the delayed data signal to the node after a delay from a first edge of a clock signal. Full Article
ni Bridge output circuit, motor driving device using the same, and electronic apparatus By www.freepatentsonline.com Published On :: Tue, 05 May 2015 08:00:00 EDT A bridge output circuit includes an output terminal, a high side transistor, a low side transistor, a high side driver for controlling a gate voltage of the high side transistor, a low side driver for controlling a gate voltage of the low side transistor, and a controller for controlling the high side and low side drivers. The low side driver includes a first current source, a second current source, and a first assist circuit. The controller is configured to control the turning-on and turning-off states of the first current source, the second current source and the first assist circuit. Full Article
ni Circuit and layout techniques for flop tray area and power otimization By www.freepatentsonline.com Published On :: Tue, 05 May 2015 08:00:00 EDT Techniques for reducing scan overhead in a scannable flop tray are described herein. In one embodiment, a scan circuit for a flop tray comprises a tri-state circuit configured to invert an input data signal and output the inverted data signal to an input of a flip-flop of the flop tray in a normal mode, and to block the data signal from the input of the flip-flop in a scan mode. The scan circuit also comprises a pass gate configured to pass a scan signal to the input of the flip-flop in the scan mode, and to block the scan signal from the input of the flip-flop in the normal mode. Full Article
ni Impedance tuning circuit and integrated circuit including the same By www.freepatentsonline.com Published On :: Tue, 12 May 2015 08:00:00 EDT An impedance tuning circuit includes a calibration unit and a post-processing unit. The calibration unit generates an initial pull-up code and an initial pull-down code by performing a calibration operation using an external resistor during an initial impedance tuning operation. The post-processing unit outputs the initial pull-up code and the initial pull-down code as a final pull-up code and a final pull-down code during the initial impedance tuning operation, and generates the final pull-up code and the final pull-down code by using the initial pull-up code and the initial pull-down code during a subsequent impedance tuning operation. Full Article
ni Liquid crystal display device and electronic device By www.freepatentsonline.com Published On :: Tue, 30 Jun 2015 08:00:00 EDT To provide a circuit used for a shift register or the like. The basic configuration includes first to fourth transistors and four wirings. The power supply potential VDD is supplied to the first wiring and the power supply potential VSS is supplied to the second wiring. A binary digital signal is supplied to each of the third wiring and the fourth wiring. An H level of the digital signal is equal to the power supply potential VDD, and an L level of the digital signal is equal to the power supply potential VSS. There are four combinations of the potentials of the third wiring and the fourth wiring. Each of the first transistor to the fourth transistor can be turned off by any combination of the potentials. That is, since there is no transistor that is constantly on, deterioration of the characteristics of the transistors can be suppressed. Full Article
ni Resonator element, resonator, electronic device, electronic apparatus, and mobile object By www.freepatentsonline.com Published On :: Tue, 21 Apr 2015 08:00:00 EDT A resonator element includes a substrate including a first principal surface and a second principal surface respectively forming an obverse surface and a reverse surface of the substrate, and vibrating in a thickness-shear vibration mode, a first excitation electrode disposed on the first principal surface, and a second excitation electrode disposed on the second principal surface, and being larger than the first excitation electrode in a plan view, the first excitation electrode is disposed so as to fit into an outer edge of the second excitation electrode in the plan view, and the energy trap confficient M fulfills 15.5≦M≦36.7. Full Article
ni Resonator element, resonator, electronic device, electronic apparatus, and mobile object By www.freepatentsonline.com Published On :: Tue, 21 Apr 2015 08:00:00 EDT A resonator element includes a substrate vibrating in a thickness-shear vibration mode, a first excitation electrode disposed on one principal surface of the substrate, and has a shape obtained by cutting out four corners of a quadrangle, and a second excitation electrode disposed on the other principal surface of the substrate, and a ratio (S2/S1) between the area S1 of the quadrangle and the area S2 of the first excitation electrode fulfills 87.7%≦(S2/S1) Full Article
ni Oscillating device, oscillating element and electronic apparatus By www.freepatentsonline.com Published On :: Tue, 21 Apr 2015 08:00:00 EDT An oscillating device includes a temperature compensated oscillator that compensates a frequency temperature characteristic in a temperature compensation range including apart of a first temperature range, and a temperature control circuit that includes a heater and controls a temperature of a quartz crystal resonator of the temperature compensated oscillator into a second temperature range included in the temperature compensation range. Further, the temperature compensation range of the temperature compensated oscillator may include a part of the first temperature range in which compensation can be performed by first-order approximation. Full Article
ni Digital system and method of estimating quasi-harmonic signal non-energy parameters using a digital Phase Locked Loop By www.freepatentsonline.com Published On :: Tue, 28 Apr 2015 08:00:00 EDT The present invention proposes a digital system and method of measuring (estimating) non-energy parameters of the signal (phase, frequency and frequency rate) received in additive mixture with Gaussian noise. The first embodiment of the measuring system consists of a PLL system tracking variable signal frequency, a block of NCO full phase computation (OFPC), a block of signal phase primary estimation (SPPE) and a first type adaptive filter filtering the signal from the output of SPPE. The second embodiment of the invention has no block SPPE, and NCO full phase is fed to the input of a second type adaptive filter. The present invention can be used in receivers of various navigation systems, such as GPS, GLONASS and GALILEO, which provide precise measurements of signal phase at different rates of frequency change, as well as systems using digital PLLs for speed measurements. Full Article
ni Vibration element, vibrator, oscillator, electronic apparatus, and moving object By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT A vibration element includes a piezoelectric substrate including a vibrating section and a thick section having a thickness larger than that of the vibrating section. The thick section includes a first thick section provided along a first outer edge of the vibrating section, a second thick section provided along a second outer edge, and a third thick section provided along another first outer edge. An inclined outer edge section that intersects with each of an X axis and a Z' axis is provided in a tip section of the piezoelectric substrate. Full Article
ni Electronic oscillation circuit By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT An electronic oscillator circuit has a first oscillator, for supplying a first oscillation signal, a second oscillator, for supplying a second oscillation signal, a first controller for delivering the first control signal as a function of a phase difference between a first controller input and a second controller input of the first controller; a second controller for delivering the second control signal as a function of a phase difference between a first controller input of the second controller and a second controller input of the second controller; a resonator; at least a second resonance frequency, with a first phase shift dependent on the difference between the frequency of a second exciting signal and the second resonance frequency and processing means, for receiving the first oscillator signal and the second oscillator signal, determining their mutual proportion, looking up a frequency compensation factor in a prestored table and outputting a compensated oscillation signal. Full Article
ni Assembly structure of electronic control unit and coil assembly of solenoid valve for electronic brake system By www.freepatentsonline.com Published On :: Tue, 05 May 2015 08:00:00 EDT An assembly structure of an electronic control unit and a coil assembly of a solenoid valve for an electronic brake system connected to the electronic control unit having a printed circuit board and applying power to the solenoid valve. The coil assembly is penetrated to allow an upper portion of the solenoid valve to be fitted thereinto, and includes a cylindrical bobbin provided with a coil and a coil case. The electronic control unit is provided with a housing having an insertion groove and joined to the hydraulic control unit, the printed circuit board being disposed spaced apart from the coil assembly, and the housing is provided with an elastic member having one end contacting the printed circuit board and the other end contacting the coil case. The elastic member is configured with a coil spring to produce different elastic forces. Full Article
ni Flush adaptor for use with a valve fitment assembly for cleaning of the assembly By www.freepatentsonline.com Published On :: Tue, 12 May 2015 08:00:00 EDT A flush adaptor for use with a valve fitment assembly for dispensing liquids from a container; wherein the flush adaptor comprises an outer ring-collar; a flange with an edge molded to the bottom of the outer ring-collar; an interior ring-collar adjacent to the outer ring-collar; a ridge molded in the interior ring-collar; a seat molded onto the interior ring-collar and a pin molded into the interior ring-collar which keeps the valve in an open position; and a hollow tube molded into the adaptor to allow the flow of liquid through the adaptor and into the fitment assembly; whereby the flush adaptor allows for cleaning of the assembly and any tubes connected thereto. Full Article
ni Methods, devices, and mediums associated with optical lift mechanism By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT An apparatus includes a light foil device configured to move based on radiation pressure associated with light received by the light foil device. The apparatus includes a mechanism configured to transition between operational states in response to the movement of the light foil device, or includes a valve configured to control a flow of material through a conduit based, at least in part, on the movement of the light foil device. Full Article
ni Water valve with supported opening function By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT Water valves and methods of regulating fluid flow for low ambient pressure water sources that reduce the amount of filtration needed for valve mechanisms operating in the water source. Full Article
ni Sheet finishing apparatus and sheet finishing method By www.freepatentsonline.com Published On :: Tue, 23 Dec 2014 08:00:00 EST According to one embodiment, a sheet finishing apparatus includes a finishing section configured to apply finishing to a sheet placed on a processing tray, a sheet discharging section configured to discharge the sheet subjected to the finishing to a stack tray via a discharge port, a roller attached to a shaft provided in parallel to the discharge port and which rotate in a first direction for guiding the sheet in the direction of the finishing section and a second direction for discharging the sheet, and an arm attached to the shaft to extend in the centrifuging direction from the shaft, rotate with the torque of the shaft, and idly rotate when force for regulating the torque acts. The arm flaps down the trailing end of the sheet on the stack tray onto the stack tray. Full Article
ni Method for operating a processing system, in which product units having different product characteristics are processed By www.freepatentsonline.com Published On :: Tue, 06 Jan 2015 08:00:00 EST A method for operating a processing system, in which product units of different formats are processed. The processing system contains a plurality of processing devices that are arranged one after the other in a processing line. In the event of a format changeover, certain component arrangements arranged in the processing system must be adapted to the new product format. In the event of an upcoming format change, a gap in the conveyed goods is generated while the conveying operation is maintained, wherein the gap in the conveyed goods runs through the processing system along the processing devices. As soon as the gap in the conveyed goods runs through a component arrangement to be adapted to the new format, the format is changed over at the component arrangement while the gap in the conveyed goods runs through the component arrangement. Full Article
ni Image forming apparatus with alignment unit By www.freepatentsonline.com Published On :: Tue, 10 Feb 2015 08:00:00 EST An image forming apparatus may include an image forming unit, a stacking unit, a control unit, and an alignment unit. The image forming unit forms an image on a recording material having a type. The stacking unit stacks the recording material on which the image formation is formed by the image forming unit. The control unit sets a predetermined number of sheets to a number that corresponds to the type of the recording material. The alignment unit aligns the recording material if the predetermined number of sheets of the recording material is stacked by the stacking unit. Full Article
ni Initiating an alignment correction cycle By www.freepatentsonline.com Published On :: Tue, 03 Mar 2015 08:00:00 EST In an embodiment, a processor-readable medium stores code representing instructions that when executed by a processor cause the processor to receive sheet length data for two paper sheets of a same standard dimension passing consecutively through a printing device. The processor calculates a length difference between the two paper sheets, and when the length difference exceeds a two-sheet threshold, it initiates an alignment correction cycle in a paper finishing device. Full Article
ni Image recording apparatus, recording-media aligning method executed by the same, and non-transitory storage medium storing instructions readable by the same By www.freepatentsonline.com Published On :: Tue, 24 Mar 2015 08:00:00 EDT An image recording apparatus includes: a recording unit for recording an image on a recording medium; a tray for supporting the recording medium recorded by the recording unit; a conveyor mechanism for conveying the recorded medium to the tray; and an alignment mechanism for aligning a plurality of recording media stacked on the tray, by application of an external force. In a period from a start to an end of recording based on one recording job, the alignment mechanism aligns the plurality of recording media stacked on the tray in a period in which image recording is not performed, and the alignment mechanism does not align the plurality of recording media stacked on the tray in a period in which image recording is being performed. Full Article
ni Semiconductor device for restraining creep-age phenomenon and fabricating method thereof By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT The present invention relates generally to a semiconductor device and, more specifically, to optimizing the creep-age distance of the power semiconductor device and a preparation method thereof. The power semiconductor device includes a chip mounting unit with a die paddle and a plurality of leads arranged side by side located close to one side edge of the die paddle in a non-equidistant manner, a semiconductor chip attached on the die paddle, and a plastic packaging body covering the die paddle, the semiconductor chip, where the plastic packing body includes a plastic extension portion covering at least a part of a lead shoulder of a lead to obtain better electrical safety distance between the terminals of the semiconductor device, thus voltage creep-age distance of the device is increased. Full Article
ni Microelectromechanical system devices having through substrate vias and methods for the fabrication thereof By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT Methods for the fabrication of a Microelectromechanical Systems (“MEMS”) devices are provided, as are MEMS devices. In one embodiment, the MEMS device fabrication method includes forming at least one via opening extending into a substrate wafer, depositing a body of electrically-conductive material over the substrate wafer and into the via opening to produce a via, bonding the substrate wafer to a transducer wafer having an electrically-conductive transducer layer, and forming an electrical connection between the via and the electrically-conductive transducer layer. The substrate wafer is thinned to reveal the via through a bottom surface of the substrate wafer, and a backside conductor is produced over a bottom surface of the substrate wafer electrically coupled to the via. Full Article
ni Nitride semiconductor and nitride semiconductor crystal growth method By www.freepatentsonline.com Published On :: Tue, 02 Jun 2015 08:00:00 EDT A base at least one principal plane of which is a nitride is prepared for use in epitaxial growth. The base is placed on a susceptor in an epitaxial growth reactor and heated to a predetermined temperature (step A). The heating is started with inactive, nitrogen gas being supplied into the reactor. Then, active, NH3 gas is supplied. Then, a growth step (step B) of a first nitride semiconductor layer is started without an intervening step of thermally cleaning the principal nitride plane of the base. In step B, the first nitride semiconductor layer is epitaxially grown on a principal nitride plane of a base without supply of an Si source material. Then, a relatively thick, second nitride semiconductor layer is epitaxially grown on the first nitride semiconductor layer by supplying an n-type dopant source material (step C). Full Article
ni Method for manufacturing organic light-emitting device By www.freepatentsonline.com Published On :: Tue, 09 Jun 2015 08:00:00 EDT A method for manufacturing a light-emitting device includes a step of forming an etching resistant protection layer on a substrate provided with an organic planarizing layer, a step of forming a plurality of electrodes on the etching resistant protection layer, a step of forming an organic compound layer on the substrate provided with the plurality of electrodes, a step of forming a resist layer on the organic compound layer formed on parts of electrodes among the plurality of electrodes using a photolithographic method, and a step of removing the organic compound layer in a region not covered with the resist layer by dry etching, wherein an entire surface of the organic planarizing layer on the substrate on which steps up to the step of forming the plurality of electrodes have been performed is covered with at least one of the etching resistant protection layer and the electrode. Full Article
ni Stacked microelectronic packages having patterned sidewall conductors and methods for the fabrication thereof By www.freepatentsonline.com Published On :: Tue, 28 Jul 2015 08:00:00 EDT Embodiments of a method for fabricating stacked microelectronic packages are provided, as are embodiments of a stacked microelectronic package. In one embodiment, the method includes arranging microelectronic device panels in a panel stack. Each microelectronic device panel includes a plurality of microelectronic devices and a plurality of package edge conductors extending therefrom. Trenches are formed in the panel stack exposing the plurality of package edge conductors. An electrically-conductive material is deposited into the trenches and contacts the plurality of package edge conductors exposed therethrough. The panel stack is then separated into partially-completed stacked microelectronic packages. For at least one of the partially-completed stacked microelectronic packages, selected portions of the electrically-conductive material are removed to define a plurality of patterned sidewall conductors interconnecting the microelectronic devices included within the stacked microelectronic package. Full Article
ni Texturing a layer in an optoelectronic device for improved angle randomization of light By www.freepatentsonline.com Published On :: Tue, 15 Sep 2015 08:00:00 EDT Embodiments generally relate to optoelectronic devices and more specifically, to textured layers in optoelectronic devices. In one embodiment, a method for providing a textured layer in an optoelectronic device includes depositing a first layer of a first material and depositing an island layer of a second material on the first layer. Depositing the island layer includes forming one or more islands of the second material to provide at least one textured surface of the island layer, where the textured surface is operative to cause scattering of light. Full Article
ni Method for producing Ga-containing group III nitride semiconductor By www.freepatentsonline.com Published On :: Tue, 17 Nov 2015 08:00:00 EST A method for producing a Ga-containing group III nitride semiconductor having reduced threading dislocation is disclosed. A buffer layer in a polycrystal, amorphous or polycrystal/amorphous mixed state, comprising AlGaN is formed on a substrate. The substrate having the buffer layer formed thereon is heat-treated at a temperature higher than a temperature at which a single crystal of a Ga-containing group III nitride semiconductor grows on the buffer layer and at a temperature that the Ga-containing group III nitride semiconductor does not grow, to reduce crystal nucleus density of the buffer layer as compared with the density before the heat treatment. After the heat treatment, the temperature of the substrate is decreased to a temperature that the Ga-containing group III nitride semiconductor grows, the temperature is maintained, and the Ga-containing group III nitride semiconductor is grown on the buffer layer. Full Article
ni Method of forming 3D integrated microelectronic assembly with stress reducing interconnects By www.freepatentsonline.com Published On :: Tue, 05 Jan 2016 08:00:00 EST A microelectronic assembly and method of making, which includes a first microelectronic element (including a substrate with first and second opposing surfaces, a semiconductor device, and conductive pads at the first surface which are electrically coupled to the semiconductor device) and a second microelectronic element (including a handler with first and second opposing surfaces, a second semiconductor device, and conductive pads at the handler first surface which are electrically coupled to the second semiconductor device). The first and second microelectronic elements are integrated such that the second surfaces face each other. The first microelectronic element includes conductive elements each extending from one of its conductive pads, through the substrate to the second surface. The second microelectronic element includes conductive elements each extending between the handler first and second surfaces. The conductive elements of the first microelectronics element are electrically coupled to the conductive elements of the second microelectronics element. Full Article
ni Enhanced patterning uniformity of gate electrodes of a semiconductor device by late gate doping By www.freepatentsonline.com Published On :: Tue, 08 Mar 2016 08:00:00 EST When forming sophisticated semiconductor-based gate electrode structures of transistors, the pre-doping of one type of gate electrode structure may be accomplished after the actual patterning of the electrode material by using an appropriate mask or fill material for covering the active regions and using a lithography mask. In this manner, a high degree of flexibility is provided with respect to selecting an appropriate patterning regime, while at the same time a uniform and superior cross-sectional shape for any type of gate electrode structure is obtained. Full Article
ni Display device substrate, display device substrate manufacturing method, display device, liquid crystal display device, liquid crystal display device manufacturing method and organic electroluminescent display device By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT The present invention provides a display device substrate, a display device substrate manufacturing method, a display device, a liquid crystal display device, a liquid crystal display device manufacturing method and an organic electroluminescent display device that allow suppressing faults derived from occurrence of gas and/or bubbles in a pixel region. The present invention is a display device substrate that comprises: a photosensitive resin film; and a pixel electrode, in this order, from a side of an insulating substrate. The display device substrate has a gas-barrier insulating film, at a layer higher than the photosensitive resin film, for preventing advance of a gas generated from the photosensitive resin film, or has a gas-barrier insulating film, between the photosensitive resin film and the pixel electrode, for preventing advance of gas generated from the photosensitive resin film. Full Article
ni Liquid crystal display device, semiconductor device, and electronic appliance By www.freepatentsonline.com Published On :: Tue, 08 Dec 2015 08:00:00 EST The liquid crystal display device includes an island-shaped first semiconductor film 102 which is formed over a base insulating film 101 and in which a source 102d, a channel forming region 102a, and a drain 102b are formed; a first electrode 102c which is formed of a material same as the first semiconductor film 102 to be the source 102d or the drain 102b and formed over the base insulating film 101; a second electrode 108 which is formed over the first electrode 102c and includes a first opening pattern 112; and a liquid crystal 110 which is provided over the second electrode 108. Full Article
ni Liquid crystal display device, semiconductor device, and electronic appliance By www.freepatentsonline.com Published On :: Tue, 15 Dec 2015 08:00:00 EST The liquid crystal display device includes an island-shaped first semiconductor film 102 which is formed over a base insulating film 101 and in which a source 102d, a channel forming region 102a, and a drain 102b are formed; a first electrode 102c which is formed of a material same as the first semiconductor film 102 to be the source 102d or the drain 102b and formed over the base insulating film 101; a second electrode 108 which is formed over the first electrode 102c and includes a first opening pattern 112; and a liquid crystal 110 which is provided over the second electrode 108. Full Article
ni Production of viral vaccines in suspension on avian embryonic derived stem cell lines By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT The present invention relates to the development and manufacturing of viral vaccines. In particular, the invention relates to the field of industrial production of viral vectors and vaccines, more in particular to the use of avian embryonic stem cells, preferably the EBx® cell line derived from chicken embryonic stem cells, for the production of viral vectors and viruses. The invention is particularly useful for the industrial production of viral vaccines to prevent viral infection of humans and animals. Full Article
ni Methods of expanding embryonic stem cells in a suspension culture By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A method of expanding and maintaining human embryonic stem cells (ESCs) in an undifferentiated state by culturing the ESCs in a suspension culture under culturing conditions devoid of substrate adherence is provided. Also provided are a method of deriving ESC lines in the suspension culture and methods of generating lineage-specific cells from ESCs which were expanded in the suspension culture of the present invention. Full Article
ni Method of selecting stem cells having high chondrogenic differentiation capability By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT Thrombospondin 1 (TSP-1), TSP-2, interleukin 17B receptor (IL-17BR) and heparin-binding epidermal growth factor-like growth factor (HB-EGF) associated with stem cell activity and use thereof. Full Article
ni Generating a mucin-producing cell from an umbilical cord amniotic membrane epithelial stem cell By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT The present invention relates to the generation of a mucin-producing cell using stem/progenitor cells obtained from the amniotic membrane of umbilical cord and therapeutic uses of such mucin-producing cells. Full Article
ni Method of washing adherent cell using trehalose-containing cell-washing solution By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT Methods of washing adherent cells, capable of effectively suppressing cell death due to proteolytic enzyme treatment for detaching the adherent cell from a culture vessel and subsequent cell treatment; cell-washing solutions used for the washing method; methods of producing cell suspensions for transplantation using the cell-washing solution; and kits comprising the cell-washing solution. Trehalose or its derivative or a salt thereof is added to physiological aqueous solutions to prepare cell-washing solutions containing trehalose or its derivative or a salt thereof as an active ingredient. The cell-washing solutions can be used to wash adherent cells before detaching the adherent cells from a culture vessel by proteolytic enzyme treatment to suppress cell death due to the proteolytic enzyme treatment. The concentration of trehalose applied to the cell-washing solution may be a concentration capable of suppressing the cell death due to the proteolytic enzyme treatment, such as 0.1 to 20 (w/v) %. Full Article
ni Small molecule antagonists of phosphatidylinositol-3,4,5-triphosphate (PIP3) and uses thereof By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT Disclosed are new members of a class of non-lipid small molecule inhibitors which interfere with the interaction between phosphoinositol-3,4,5-triphosphate (PIP3) and pleckstrin homology (PH) domains. These molecules target a broad range of PIP3-dependent signaling events in vitro and exert significant anti-tumor activity in vivo, with improved activity and selectivity toward particular PH domains. The small molecule inhibitors of the invention can be used alone or together with tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) or other cancer medicament to treat cancer. Small molecule inhibitors of the invention act synergistically in combination with TRAIL and with other Akt inhibitors in treating cancer. Pharmaceutical compositions and methods for treating cancer are provided. Full Article
ni Plants having altered agronomic characteristics under nitrogen limiting conditions and related constructs and methods involving genes encoding LNT1 polypeptides and homologs thereof By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT Isolated polynucleotides and polypeptides and recombinant DNA constructs particularly useful for altering agronomic characteristics of plants under nitrogen limiting conditions, compositions (such as plants or seeds) comprising these recombinant DNA constructs, and methods utilizing these recombinant DNA constructs. The recombinant DNA construct comprises a polynucleotide operably linked to a promoter functional in a plant, wherein said polynucleotide encodes an LNT1 polypeptide. Full Article
ni Genes regulating plant branching, promotors, genetic constructs containing same and uses thereof By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT The invention relates to genes coding for TCP family transcription factors and having a biological role in the development of axillary buds and branch growth. Furthermore, the invention relates to the promoters of the transcription of said genes, to the genetic constructs containing same and to the uses thereof, including the use of agents that modulate the expression of these genes in order to modify plant architecture. Full Article
ni Methods and systems for manipulating particles using a fluidized bed By www.freepatentsonline.com Published On :: Tue, 28 Jul 2015 08:00:00 EDT The present invention comprises methods and systems for manipulation of media and particles, whether inert materials or biomaterials, such as cells in suspension cell culture. The methods and systems comprise use of an apparatus comprising a rotating chamber wherein the actions of the combined forces fluid flow force and centrifugal force form a fluidized bed within the rotating chamber. Full Article
ni Method of determining the nucleotide sequence of oligonucleotides and DNA molecules By www.freepatentsonline.com Published On :: Tue, 04 Aug 2015 08:00:00 EDT The present invention relates to a novel method for analyzing nucleic acid sequences based on real-time detection of DNA polymerase-catalyzed incorporation of each of the four nucleotide bases, supplied individually and serially in a microfluidic system, to a reaction cell containing a template system comprising a DNA fragment of unknown sequence and an oligonucleotide primer. Incorporation of a nucleotide base into the template system can be detected by any of a variety of methods including but not limited to fluorescence and chemiluminescence detection. Alternatively, microcalorimetic detection of the heat generated by the incorporation of a nucleotide into the extending template system using thermopile, thermistor and refractive index measurements can be used to detect extension reactions. Full Article
ni Protein concentrate and an aqueous stream containing water-soluble carbohydrates By www.freepatentsonline.com Published On :: Tue, 05 Jan 2016 08:00:00 EST Disclosed are process for contacting a protein containing material with one or more wet-mill streams. The protein content of the protein containing material is increased. Full Article
ni Mitigation of odor in cleaning machines and cleaning processes By www.freepatentsonline.com Published On :: Tue, 05 Jan 2016 08:00:00 EST The invention relates to malodor controlling bacteria and related methods and compositions for the control and prevention of malodor. Full Article
ni Method for producing sialic-acid-containing sugar chain By www.freepatentsonline.com Published On :: Tue, 28 Jun 2016 08:00:00 EDT [Problem to be Solved] The importance of sugar chains having α2,3- or α2,6-linked sialic acid at their non-reducing ends is known. Industrial production has been demanded for these sugar chain compounds. Particularly, the production of glycoprotein drugs or the like inevitably requires producing in quantity sugar chains having homogeneous structures by controlling the linking pattern (α2,6-linkage or α2,3-linkage) of sialic acid. Particularly, a triantennary or tetraantennary N-type complex sugar chain having sialic acid at each of all non-reducing ends is generally considered difficult to chemically synthesize. There has been no report disclosing that such a sugar chain was chemically synthesized. Furthermore, these sugar chains are also difficult to efficiently prepare enzymatically.[Solution]The present inventors have newly found the activity of sialyltransferase of degrading sialic acid on a reaction product in the presence of CMP and also found that formed CMP can be degraded enzymatically to thereby efficiently produce a sialic acid-containing sugar chain. The present inventors have further found that even a tetraantennary N-type sugar chain having four α2,6-linked sialic acid molecules, which has previously been difficult to synthesize, can be prepared at high yields by one-pot synthesis comprising the elongation reaction of a biantennary sugar chain used as a starting material without performing purification after each enzymatic reaction. Full Article
ni Stackable chair with telescopic leg mechanism By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT A chair for facilitating efficient stacking includes a seat element having a seat frame, a plurality of front legs attached to a front portion of the seat element, a plurality of rear legs attached to a back portion of the seat element, and one or more telescopic leg mechanisms disposed on at least one of the front or rear legs, wherein the telescopic leg mechanisms provide for lateral movement of the at least one of the front or rear legs with respect to the seat element. Full Article
ni Operating unit for installation in an aircraft cabin By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT An operating unit (1) for installation in an aircraft cabin comprises an operating unit front side (10) and an operating unit rear side (20), at least one operating element (12, 14) attached in the region of the operating unit front side (10) and accessible to a user, and a holding device (40) for attaching the operating unit (1) to a monument (30) accommodating the operating unit (1) in its state mounted in the aircraft cabin. The holding device (40) is designed to attach the operating unit (1) in its state mounted in the aircraft cabin to the monument (30), in a first position or in a second position, as desired, the operating element (12, 14) in the second position of the operating unit (1) being situated in a spatial position which is lowered with respect to the spatial position of the operating element (12, 14) in the first position of the operating unit (1) and/or is displaced in a direction parallel to an imaginary straight line connecting the operating unit rear side (20) to the operating unit front side (10). Full Article
ni Zero-wall clearance linkage mechanism for a lifting recliner By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A seating unit that includes a linkage mechanism adapted to move the seating unit between seat-lift, closed, extended, reclined, and seat-lift positions is provided. The linkage mechanism includes a seat-mounting plate mounted to a footrest assembly, a base plate fixedly mounted to a lift assembly, a back-mounting link rotatably coupled to the seat-mounting plate, a seat-adjustment assembly with a bellcrank, and a linear actuator for automating adjustment of the linkage mechanism. In operation, a stroke in a first phase of the linear actuator generates a force on the bellcrank that translates the seat-mounting plate rearward in a consistent angle of inclination and rotates the back-mounting link from a reclined to an upright orientation. A stroke in a second phase acts to collapse the footrest assembly. A stroke in a third phase causes the lift assembly to raise and tilt the seating unit, thereby accommodating egress and ingress of an occupant. Full Article
ni Crash indication system for a reclining ride down child seat By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT More specifically, the crash indication system for a child safety seat includes a seat bottom. A base is provided for supporting the seat bottom, which is slidably connected to the bases so that the seat body is movable relative to the base, between a resting position and a ride down position, a position due to a change in environmental forces. The seat body is adjustably affixed to a carriage to set a recline position. An indicator member is attached to the carriage and moves therewith to visually track and monitor the movement of the seat. When ride down of the seat occurs due to a change in forces to the seat, the indicator member moves with the sliding carriage to reflect a ride down position of the seat bottom. A ratchet connection is provided to prevent the carriage from going back to its resting position. Full Article
ni Height adjustment mechanism suitable for a footring By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A mechanism for vertically adjusting a component on a shaft has a collet sleeve riding on the shaft. A spiral track of the component's hub receives a radially outwardly projecting pin on the collet sleeve. The outer surface of the collet sleeve and the inner surface of the hub are tapered so that the hub can rotated one direction to advance the hub on the collet sleeve and compress the collet sleeve onto the shaft to frictionally lock the collet sleeve to the shaft. Because the hub is joined to the collet sleeve by the pin, this also locks the vertical position of the component. Conversely, the hub can be oppositely rotated to release the compression of the collet sleeve so that the collet sleeve, and therefore the vertical component, is slidable on the shaft. Full Article