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Consensus document on composition of new soybean varieties: food and feed nutrients, anti-nutrients, toxicants and allergens

This revised document supplies basic information (compositional considerations, key constituents), useful in risk/safety assessment of food and feed using new varieties of soybean (Glycine max.). This updated publication replaces the original issue of 2001.




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Guidance on Sample Preparation and Dosimetry for the Safety Testing of Manufactured Nanomaterials

This is a guidance on sample preparation and dosimetry, to which special attention should be paid when testing nanomaterials for human health and environmental safety endpoints.




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Report of OECD Workshop on Natech Risk Management (Natural-hazard triggered technological accidents)

This is the report of the workshop on Natural-hazard triggered technological accidents (Natech) that took place 23-25 May 2012. It investigated the specific elements of the prevention of, preparedness for, and response to chemical accidents caused by natural hazard or natural disaster.




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Current Developments/Activities on the Safety of Manufactured Nanomaterials

This document provides information on current/planned activities related to the safety of manufactured nanomaterials in OECD member and non-member countries that attended at the 10th meeting of OECD’s Working Party on Manufactured Nanomaterials (Paris France, 27-29 June 2012).




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Global Pollutant Release And Transfer Register: Proposal for a harmonised list of reporting sectors

This document compares sectors of industrial activities and their reporting thresholds among different national / regional PRTRs to improve the comparability of PRTR data, and proposes a harmonised list of sectors.




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Malaysia joins OECD agreement on mutual acceptance of chemical safety data

Malaysia has joined the OECD system for the Mutual Acceptance of Data (MAD) in the Assessment of Chemicals, ensuring that its non-clinical safety data related to the protection of human health and the environment will be accepted by all 40 countries adhering to MAD.




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Carbon Capture and Long-Term Storage: Analysis of 2010 Survey

This is an analysis of a 2010 survey regarding carbon capture and long-term storage (CCS). It provides information that helps understand the hazards of CO2 sequestration and the risks to human health and environmental safety. It also identifies accident scenarios, including those associated with CO2 capture and compression, storage prior to transport and injection for geological storage.




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Guidance for Assessment of the Efficacy of Baits Against Garden Ants

This biocide document provides guidance on the conduct of laboratory and field tests aimed to assess the efficacy of anti-ants baits for indoor use. A bait contains one or more insecticidal active ingredients combined with food for garden ants.




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The Australian Pesticides and Veterinary Medicines Authority (APVMA) database of completed chemical reviews is now searchable in eChemPortal

The Australian Pesticides and Veterinary Medicines Authority (APVMA) database of completed chemical reviews including (in some cases) detailed risk assessment reports addressing human health and the environment. A review, initiated from new concerns, may lead to the reconsideration of the registration of agricultural and veterinary chemicals in the marketplace if potential risks to safety and performance have been identified.




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Co-Operation on Risk Assessment: Prioritisation of Important Issues on Risk Assessment of Manufactured Nanomaterials - Final Report

This document follows on from a report entitled Important Issues on Risk Assessment of Manufactured Nanomaterials [ENV/JM/MONO(2012)8]. This report identified a range of issues which the WPMN considered important in risk assessment and which should be addressed in the future. It summarised results of a survey which was circulated to delegations of the WPMN, methodologies used to analyze the survey, and the identified priorities.




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The Gefahrstoffdatenbank der Länder is now linked to eChemPortal

The Gefahrstoffdatenbank der Länder, a german database, is now linked to eChemPortal. 102545 substance records can be searched through the substance search. This includes German hazardous substances legislation as well as other sources reflecting the state of technology and occupational health and safety relating to activities involving hazardous substances. In addition, it contains links to various other German data bases.




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Low-level presence of transgenic plants in seed and grain commodities: Environmental risk/safety Assessment, and availability and use of information

This Biosafety document aims to serve as an aid to risk assessors and regulators; providing guidance on handling the aspects of an environmental safety assessment, accessing and using information in situations of low-level presence (LLP) of transgenic plants in seed and grain commodities.




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OECD countries address the safety of manufactured nanomaterials

The OECD has recommended its Member Countries apply existing international and national chemical regulatory frameworks to manage the risks associated with manufactured nanomaterials.




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Consensus document on compositional considerations for new varieties of oyster mushroom (Pleurotus ostreatus): Key food and feed nutrients, anti-nutrients and toxicants

This document supplies basic information useful in the risk and safety assessment of food and feed using new varieties of oyster mushroom: compositional considerations, key constituents (nutrients, anti-nutrients and toxicants). It is issued in the Novel Food and Feed Safety Series.




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Consensus document on the biology of sugarcane (Saccharum spp.)

This new document is available as a tool for environmental safety assessment of new varieties of sugarcane derived from modern biotechnology. Given the large production of this crop worldwide, its biosafety will be an important issue for many countries.




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Report of the 4th OECD BioPesticides Steering Group seminar on trichoderma spp. for use in plant protection products

This Bio-pesticides seminar report presents an overview of similarities and differences between species and strains within the Trichoderma genus. This fungus illustrates many general issues related to the use of micro-organisms for pest management.




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Ecotoxicology and Environmental Fate of Manufactured Nanomaterials: Test Guidelines

This document includes the conclusions and recommendations resulting from a workshop that addressed the ecotoxicology and environmental fate of manufactured nanomaterials, and in particular the applicability of existing OECD Test Guidelines (TG) related to these topics. A number of TG developments are underway at OECD as a follow-up to these recommendations.




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Report of the OECD Seminar on Indicators for Integrated Pest Management

This report describes an OECD seminar that brought together regulatory authorities, industry representatives and other stakeholders to discuss how to measure the uptake, adoption and implementation, as well as the impact, of Integrated Pest Management. Integrated Pest Management, a term used to describe strategies that promote the safer and more sustainable use of pesticides, is high on the agenda in many regions of the world.




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Emission scenario document on formulation and application of thermal and carbonless copy paper

This document provides information on the sources, use patterns, and potential release pathways of chemicals used in the manufacture of thermal and carbonless copy paper. It presents approaches for estimating the environmental releases of and occupational exposures to additives and components used in thermal and carbonless copy paper coatings.




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Guidance on grouping of chemicals, second edition

The OECD has published the second edition of the guidance on grouping of chemicals. This edition has been augmented with experience and examples encountered in the OECD Cooperative Chemicals Assessment Programme. It also introduces new or revised guidance on elaborating the analogue and category approach, quantitative and qualitative read-across, justifying read-across, and using bioprofiling results for grouping chemicals.




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Report of the OECD/KEMI/EU workshop on microbial pesticides: assessment and management of risks

A report of the 2013 joint OECD/Swedish Chemicals Agency/European Commission workshop on the assessment and management of risks of microbial pesticides that resulted in 20 recommendations for approaches that could be taken now and areas for follow-up work to be undertaken by OECD or Member countries.




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Removal/emission predictions of wastewater treatment for exposure assessment and Pollutant Release and Transfer Registers

This document compiles information on the current methodologies, tools and models and helps readers identify appropriate models/ and methodologies for estimating substance-specific removal/emissions from wastewater treatment systems. It could support efforts to improve these models and tools.




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Consensus document on the biology of cassava

This document is a tool for environmental safety assessment of novel varieties of Cassava derived from modern biotechnology. Cassava is a key staple crop in Africa, Asia and Latin America, this document will be useful to many readers interested in biosafety issues.




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Weight of evidence assessment for the skin sensitisation potential of 4-isopropylaniline

This OECD monograph demonstrates how a chemical hazard assessment that considers and ranks all available relevant information - a so-called weight of evidence approach - can be constructed to conclude on a particular hazard endpoint for a chemical, in this case, skin sensitisation for 4-isopropylaniline.




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Report of the OECD expert meeting on the physical chemical properties of manufactured nanomaterials and test guidelines

This report includes the conclusions and recommendation of an expert workshop on Physical-Chemical Properties of Manufactured Nanomaterials and Test Guidelines organized by OECD’s Working Party on Manufactured Nanomaterials. The workshop addressed issues relevant to the physical-chemical properties of manufactured nanomaterials from a regulatory perspective point with a view to the need for new or adapted test guidelines.




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New scoping document on in vitro and ex vivo assays for the identification of modulators of thyroid hormone signalling

This scoping document brings forward relevant in vitro and ex vivo thyroid assays to the attention of OECD member countries, and provide recommendations for their further development/use, and also, to identify aspects of the thyroid signalling pathway that are not covered and would require further attention




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Report of an OECD survey on the assessment of the risks from obsolete pesticides in OECD countries

OECD has published a report of a survey that provides information and recommendations on how to deal with stocks of “obsolete” pesticides in OECD member (and partner) countries. Such pesticides’ obsolescence can arise for a number of reasons including product deterioration, product de-registration, and product revision.




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Report of an OECD survey on risk management/mitigation approaches and options related to agricultural pesticide use near residential areas

This report of a survey collates member countries’ approaches to manage and mitigate the risk of pesticide use near residential areas.




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The joint Substance Data Pool of the German Federal Government and the German Federal States (GSBL) is the 30th database linked to eChemPortal

The Joint Substance Data Pool of the German Federal Government and Federal States (GSBL) is now linked to eChemPortal. Records contain information on physical and chemical properties, on ecotoxicological and toxicological parameters and on environmental fate. They provide descriptions of environmental hazards, health dangers, fire and other technical hazards and give information on relevant chemicals-related legislation.




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Consensus document on the biology of Eucalyptus spp.

This publication is a tool for environmental safety assessment of EUCALYPTUS novel lines. Planted in the tropics and sub-tropics, E. species can be genetically-engineered for resistance to disease/drought/cold/salinity, or lower lignin content. Elements useful to biosafety evaluation are detailed, e.g. Eucalyptus taxonomy, origin, reproduction, genetics, hybridisation, ecology, allergens-toxins, beneficial chemical products, breeding.




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OECD Guidance on the GLP Requirements for Peer Review of Histopathology

This advisory document provides guidance on how pathology peer reviews should be planned, conducted and reported within the context of OECD Good Laboratory Practice.




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New, updated and corrected OECD Test Guidelines for the testing of chemicals – 26 September 2014

On 26 September 2014, the OECD Council adopted three new, five updated and one corrected OECD Test Guidelines for the testing of chemicals.




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Report of the pilot exercise on classifications for selected chemicals assessed at CoCAM

The OECD has published a report on a pilot chemical classification exercise undertaken in 2013 and ‘14. Using a number of chemical assessments agreed in the OECD hazard assessment programme, reasons why classification proposals may differ were investigated. The report concludes on the main reasons for such differences, and recommends some measures to overcome some of them.




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OECD encourages the development of non-animal test methods for the detection of thyroid disrupters

The OECD Advisory Group on Endocrine Disrupters Testing and Assessment met on 16-17 October 2014 in Paris to discuss the development and update of Test Guidelines and related documents for endocrine disrupters testing and assessment.




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Global Pollutant Release and Transfer Register (PRTR): Proposal for a harmonised list of pollutant

PRTR have been established throughout the world to track releases and transfers of potentially harmful chemicals. But most of the PRTR systems were designed without considering comparability, each PRTR has its own requirement of reporting chemicals and sectors. To harmonise globally, OECD reviewed the reporting chemicals and sectors across PRTR systems and produced proposal for harmonised lists of reporting pollutants.




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Guidance document on elements of a Pollutant Release and Transfer Registers (PRTR): Part 1

OECD countries have developed PRTR system to track releases and transfers of potentially harmful chemicals. To improve PRTR system, OECD have analysed common elements (pollutants, sectors) in different PRTR systems, mainly focus on institutional arrangement. This serves as a common framework for different PRTR system, and supporting materials for a country that intends to develop or update its PRTR.




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Biosafety and the Environmental Uses of Micro-Organisms

Micro-organisms play a fundamental role in the environment. Yet their role is the result of complex biogeochemical processes by consortia of micro-organisms and the function of individual species is not clear in many cases. This publication provides an overview of the current situation and relevant developments in environmental microbiology.




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Launch of 2 OECD Test Guidelines on human hazard endpoint skin sensitisation

The OECD has just published two new Test Guidelines on human health hazard endpoint skin sensitisation. Skin sensitisation refers to an allergic response following skin contact with the tested chemical, as defined by the United Nations Globally Harmonized System of Classification and Labelling of Chemicals (UN GHS).




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A new guidance is now available to facilitate the ecological risk assessment of organometallic and organic metal salt substances

The OECD has published guidance to facilitate the ecological risk assessment of organometallic and organic metal salt substances. A strategy is presented based on key steps that first consider the fate of these substances in the environment, the identification of moieties of concern, and subsequently the selection of an appropriate path forward to either assess the inorganic moiety and/or the individual substance.




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Expansion of Brazil's scope under OECD agreement on mutual acceptance of chemical safety data

In 2011, Brazil joined OECD’s Mutual Acceptance of Data (MAD) system ensuring that its chemical safety test data will be accepted by all 40 countries adhering to MAD. Originally limited to data developed in Brazil on pesticides, biocides and industrial chemicals, it now also includes veterinary products, feed additives, cosmetics, pharmaceutical products, sanitizers, wood preservative and treatments of effluents and natural ecosystems.




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Safety Assessment of Foods and Feeds Derived from Transgenic Crops, Volume 1

Volume I of this series compiles the science-based consensus documents of the OECD Task Force for the Safety of Novel Foods and Feeds from 2002 to 2008.




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OECD improves access to information on the classification of chemicals

The OECD eChemPortal, a web portal which offers comprehensive information on chemical substances, has been updated to offer better access to chemical classifications according to the Globally Harmonized System of Classification and Labelling of Chemicals (GHS).




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Newly published set of Test Guidelines

A set of new and updated OECD Test Guidelines was published at the end of July 2015 to test chemicals and identify hazards such as endocrine disruption, serious eye damage, genotoxicity, skin irritation or corrosion.




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Reports to support efforts in the framework of the Strategic Approach to International Chemicals Management

The OECD/UNEP Global PFC group has published two new reports to support efforts in the framework of the Strategic Approach to International Chemicals Management (SAICM) to improve information sharing at a global level on perfluorinated chemistries.




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Developments on the safety of manufactured nanomaterials: 2013

This document provides background information on activities related to manufactured nanomaterials, as well as other activities on nanotechnologies at the international level. The information provided in this document captures OECD activities between February and December 2013.




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Fundamental and Guiding Principles for (Q)SAR Analysis of Chemical Carcinogens with Mechanistic Considerations

The OECD has published fundamental and guiding principles to facilitate the application of QSAR methods to the risk assessment of chemicals. The main focus is on the critical role of mechanistic consideration in improving various (Q)SAR approaches and possible integrative approaches of combining chemoinformatics and bioinformatics.




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Physical-Chemical Properties of Nanomaterials: Evaluation of Methods Applied in the OECD-WPMN Testing Programme

This new document focuses on the evaluation of test methods applied to determine the physico-chemical properties of different types of nanomaterials.




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Application of Good Laboratory Practice Principles to Computerised Systems

This new Advisory Document replaces the 1995 consensus document on the Application of the Principles of GLP to Computerised Systems. It retains all of the key text from the original 1995 document, but includes new text to reflect the current state-of-the art in this field.




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German database Information system für gefährliche Stoffe IGS

German database Information system für gefährliche Stoffe IGS is now linked to eChemPortal. The IGS provides public access to a variety of information on chemical and microbiological substances mostly in German. The focus is on regulatory information reflecting German and European, as well as Swiss, US and selected other legislation and assessments. Beside this, information on substance data and emergency procedures is available.




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Classification and Labelling of Chemicals

Results of a joint pilot project of the OECD and the UN Sub-Committee of Exports on the Globally Harmonised System of Classification and Labelling of Chemicals (UNSCEGHS) including a report of the results of the pilot and non-biding proposed classifications for three substances.