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A photothermal-hypoxia sequentially activatable phase-change nanoagent for mitochondria-targeting tumor synergistic therapy

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00003E, Paper
Jia Qu, Dengke Teng, Guoqing Sui, Shihui Guan, Yang Wang, Qimeihui Wang, Yuanqiang Lin, Haitao Ran, Zhigang Wang, Hui Wang
The advantages of PCM@Lip/IT NPs include mitochondrial-targeting, on-demand drug release, and prodrug activation by hypoxia with guidance/monitoring by PA and FL imaging.
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19 F magnetic resonance imaging enabled real-time, non-invasive and precise localization and quantification of the degradation rate of hydrogel scaffolds in vivo

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00278J, Paper
Qinghua Li, Zujian Feng, Huijuan Song, Jianhua Zhang, Anjie Dong, Deling Kong, Weiwei Wang, Pingsheng Huang
19 F MRI is able to precisely monitor the localization and quantify the degradation rate of implantable/injectable hydrogels in real-time and noninvasive manner, with no interference of endogenous background signals and limitation of penetration depth.
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Tumor localization of oncolytic adenovirus assisted by pH-degradable microgels with JQ1-mediated boosting replication and PD-L1 suppression for enhanced cancer therapy

Biomater. Sci., 2020, 8,2472-2480
DOI: 10.1039/D0BM00172D, Paper
Haishi Qiao, Xingmei Chen, Qiming Wang, Junmei Zhang, Dechun Huang, Enping Chen, Hongliang Qian, Yinan Zhong, Qi Tang, Wei Chen
Illustration of pH-degradable microgels (MGs) for the simultaneous encapsulation of OA and JQ1 for an enhanced oncolytic viral treatment with JQ1-meidated boosting viral replication and PD-L1 suppression.
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A transport system based on a quantum dot-modified nanotracer is genetically and developmentally stable in pregnant mice

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00311E, Paper
Open Access
Hye Jin Kim, Ji Sun Park, Se Won Yi, Minyeon Go, Hye-Ryun Kim, Su Jin Lee, Jong Min Park, Dong Hyun Cha, Sung Han Shim, Keun-Hong Park
The use of nanoscale materials (NMs) could cause problems such as cytotoxicity, genomic aberration, but the impacts of NM exposure during pregnancy remain uncharacterized in the context of clinical applications.
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Eco-friendly synthesis of glutathione-capped CdTe/CdSe/ZnSe core/double shell quantum dots: their cytotoxicity and genotoxicity effects on Chinese hamster ovary cells

Toxicol. Res., 2019, 8,868-874
DOI: 10.1039/C9TX00113A, Paper
Neo Mervyn Monaheng, Sundararajan Parani, Mary Gulumian, Oluwatobi Samuel Oluwafemi
In this work, we report green one-pot synthesis, cytotoxicity and genotoxicity of glutathione-capped CdTe/CdSe/ZnSe heterostructured quantum dots (QDs) using a label-free xCELLigence RTCA system as well as the Cytokinesis Blocked Micronucleus assay.
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Lipoic acid antagonizes paraquat-induced vascular endothelial dysfunction by suppressing mitochondrial reactive oxidative stress

Toxicol. Res., 2019, 8,918-927
DOI: 10.1039/C9TX00186G, Paper
Li Pang, Ping Deng, Yi-dan Liang, Jing-yu Qian, Li-Chuan Wu, Ling-ling Yang, Zheng-ping Yu, Zhou Zhou
α-Lipoic acid antagonizes paraquat toxicity.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Cadmium telluride quantum dot-exposed human bronchial epithelial cells: a further study of the cellular response by proteomics

Toxicol. Res., 2019, 8,994-1001
DOI: 10.1039/C9TX00126C, Paper
Yan-Ming Xu, Heng Wee Tan, Wei Zheng, Zhan-Ling Liang, Fei-Yuan Yu, Dan-Dan Wu, Yue Yao, Qiu-Hua Zhong, Rui Yan, Andy T. Y. Lau
A comparative proteome analysis was conducted to identify global changes in the protein expression profiles of cadmium telluride quantum dot-exposed human bronchial epithelial BEAS-2B cells.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Nanoparticle induced barrier function assessment at liquid–liquid and air–liquid interface in novel human lung epithelia cell lines

Toxicol. Res., 2019, 8,1016-1027
DOI: 10.1039/C9TX00179D, Paper
Open Access
Lars Leibrock, Sandra Wagener, Ajay Vikram Singh, Peter Laux, Andreas Luch
To answer questions about nanoparticle toxicity, translocation and biokinetics following inhalation exposure, in vitro models should have functional barrier properties to mimic the in vivo situation as closely as possible.
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Benzoquinone alters the lipid homeostasis in Saccharomyces cerevisiae

Toxicol. Res., 2019, 8,1035-1041
DOI: 10.1039/C9TX00139E, Paper
Abhishek Raj, Vasanthi Nachiappan
BQ exposure inhibited cell growth, increased the ROS-mediated apoptosis, and altered the phospholipids that resulted in membrane proliferation.
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The protective effect of thymoquinone on tert-butylhydroquinone induced cytotoxicity in human umbilical vein endothelial cells

Toxicol. Res., 2019, 8,1050-1056
DOI: 10.1039/C9TX00235A, Paper
Zahra Karimi, Maryam Ghaffari, Jafar Ezzati Nazhad Dolatabadi, Parvin Dehghan
2-tert-Butyl-4-hydroquinone (TBHQ) is used for inhibition of oxidative rancidity in the food industry.
The content of this RSS Feed (c) The Royal Society of Chemistry




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HC orders closure of Liquor shops in Tamil Nadu, allows online sales

The opening of shops in districts, except Chennai on May 7, has resulted in people thronging the outlets without maintaining social distancing norms




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Release of graphene-related materials from epoxy-based composites: characterization, quantification and hazard assessment in vitro

Nanoscale, 2020, Advance Article
DOI: 10.1039/C9NR10245K, Paper
Open Access
Woranan Netkueakul, Daria Korejwo, Tobias Hammer, Savvina Chortarea, Patrick Rupper, Oliver Braun, Michel Calame, Barbara Rothen-Rutishauser, Tina Buerki-Thurnherr, Peter Wick, Jing Wang
We measured the cytotoxicity of pristine GRMs and the abraded particles from epoxy/GRM composites, which indicated low risks to consumers of such composites.
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The content of this RSS Feed (c) The Royal Society of Chemistry




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Spin-coated fluorinated PbS QD superlattice thin film with high hole mobility

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR02299C, Paper
Pan Xia, Daniel Davies, Bijal Patel, Maotong Qin, Zhiming Liang, Kenneth R Graham, Ying Diao, Ming Lee Tang
Motivated by the oleophobic and electron-withdrawing nature of perfluorocarbons, we explore the effect of a trifluoromethyl coating on lead sulfide quantum dots (PbS QDs) in thin film transistor (TFT) geometry....
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Realization of high-quality optical nanoporous gradient-index filters by optimal combination of anodization conditions

Nanoscale, 2020, 12,9404-9415
DOI: 10.1039/C9NR10526C, Paper
Cheryl Suwen Law, Siew Yee Lim, Lina Liu, Andrew D. Abell, Lluis F. Marsal, Abel Santos
High-quality nanoporous anodic alumina gradient-index filters are realized by sinusoidal pulse anodization under optimized anodization conditions.
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Ionic liquid assisted preparation and modulation of the photoluminescence kinetics for highly efficient CsPbX3 nanocrystals with improved stability

Nanoscale, 2020, 12,9569-9580
DOI: 10.1039/D0NR00579G, Paper
Ting Chen, Yanqiao Xu, Zhixiang Xie, Weihui Jiang, Lianjun Wang, Wan Jiang
A facile approach was performed to synthesize CsPbBr3 NCs with the assistance of ionic liquid [Bmim]Br, which could modulate the surface property and enhace the stability of NCs effectively.
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Effective atherosclerotic plaque inflammation inhibition with targeted drug delivery by hyaluronan conjugated atorvastatin nanoparticles

Nanoscale, 2020, 12,9541-9556
DOI: 10.1039/D0NR00308E, Paper
Seyedmehdi Hossaini Nasr, Zahra Rashidijahanabad, Sherif Ramadan, Nate Kauffman, Narayanan Parameswaran, Kurt R. Zinn, Chunqi Qian, Ripla Arora, Dalen Agnew, Xuefei Huang
Atherosclerosis is associated with inflammation in the arteries. Hyaluronan atorvastatin nanoparticle conjugate could target CD44 overexpressed in atherosclerotic plaques and significantly reduce plaque associated inflammation.
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A novel split mode TFBAR device for quantitative measurements of prostate specific antigen in a small sample of whole blood

Nanoscale, 2020, 12,9647-9652
DOI: 10.1039/D0NR00416B, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Ewelina Wajs, Girish Rughoobur, Keith Burling, Anne George, Andrew J. Flewitt, Vincent J. Gnanapragasam
TFBAR technology demonstrates a cost-effective means for point-of-care diagnostics and monitoring of PSA.
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Quantitative encapsulation and retention of 227Th and decay daughters in core–shell lanthanum phosphate nanoparticles

Nanoscale, 2020, 12,9744-9755
DOI: 10.1039/D0NR01172J, Paper
M. Toro-González, A. N. Dame, C. M. Foster, L. J. Millet, J. D. Woodward, J. V. Rojas, S. Mirzadeh, S. M. Davern
La(227Th)PO4 core +2 shells nanoparticles retained >99.75% of activity from 227Th and decay daughters (223Ra, 211Pb) for targeted alpha therapy.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Double Fano resonances in hybrid disk/rod artificial plasmonic molecules based on dipole-quadrupole coupling

Nanoscale, 2020, 12,9776-9785
DOI: 10.1039/D0NR00461H, Paper
Zhiquan Chen, Shi Zhang, Yiqin Chen, Yanjun Liu, Ping Li, Zhaolong Wang, Xupeng Zhu, Kaixi Bi, Huigao Duan
Double Fano resonances can be aroused in a simple disk and rods coupled artificial plasmonic molecule. Two Fano peaks can be independently tuned by changing one rod length or the gap distances between rods and disk.
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High brightness blue light-emitting diodes based on CsPb(Cl/Br)3 perovskite QDs with phenethylammonium chloridesynonym passivation.

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR02597F, Paper
He Shao, Yue Zhai, Xiufeng Wu, Wen Xu, Lin Xu, Biao Dong, Xue Bai, Haining Cui, Hongwei Song
All inorganic perovskite quantum dots (QDs) (CsPbX3, X=Cl, Br, I) have been applied on the light-emitting devices (LEDs) in recent years due to their excellent optical and optoelectronic properties. However,...
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A unique synthesis of rare-earth-Co-based single crystal particles by “self-aligned” Co nano-arrays

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR00490A, Paper
Qiong Wu, Liying Cong, Yue Ming, Chenglin Li, Zhenhui Ma, Xiangyu Ma, Yatao Wang
In this study, anisotropic SmCo5 magnets were prepared by a distinctive method, which is the high-temperature reductive annealing of Co@Sm2O3 with specially designed nanostructure. High resolution transmission electron microscope and...
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Electric field triggered release of gas from a quasi-one-dimensional hydrate in the carbon nanotube

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR01113D, Paper
Jiaxian Li, Hangjun Lu, Xiaoyan Zhou
We systematically investigate the effects of an axial electric field on the formation and decomposition of quasi-one-dimensional nitrogen gas hydrates within a single-walled carbon nanotube (SWNT) by using molecular dynamics...
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Direct carbonization of organic solvent toward graphene quantum dots

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR01903H, Communication
Hongji Liu, Xiaotong Lv, Changwei Li, Yong Qian, Xingyu Wang, Lin Hu, Yu-Cai Wang, Wenchu Lin, Hui Wang
The bottom-up synthesis of graphene quantum dots (GQDs) using solvothermal method has attracted considerable attention because of their fewer defects and controllable size/ morphology. However, the influence of organic solvent...
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Let me draw you a map: knowledge management from "two completely different streams of thought"

Let me draw you a map: knowledge management from "two completely different streams of thought" HeavyHead, Danielle; Greenshields, Mary This paper represents the results of a conversation between Adrienne Heavy Head, the creator and manager of the Blackfoot Digital Library (BDL), at the University of Lethbridge in Alberta, Canada, and Mary Greenshields, a new librarian in Alberta. The aim of the conversation was for Mary, a settler living in traditional Blackfoot Territory, to learn about the creation and maintenance of the BDL and to gain insight into the organization, access, and classification of information within the library as a real-life example of some of the Protocols suggested by the Canadian Federation of Library Associations. Adrienne and Mary hope that this conversation will help librarians to better understand knowledge management from a Blackfoot perspective and might inspire librarians to start and continue such conversations with the Indigenous peoples upon whose lands their libraries rest. Open access article. Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0) applies.




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Picturesque homestead reflects pioneer living in Florida




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"Dem spooks" pilot car for you backing uphill




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Billy Graham trembled before first "crusade" at Peniel




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Quina House retains Jacksonian era characteristics




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'Damn those Confederate torpedoes" - Farragut




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"Way down upon de Swanee Ribber"




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"It is not anybody's damn business..."




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World's most unique monument




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"Tampa Town" was launching pad for Jules Verne




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Queen of England gave gifts to Lakeland Church




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The monument to unrequited love




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"Flagler's Folly" linked Key West to Mainland




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San-ai-an, "the adobe of three loves"




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The "little governor" from Arizona founded Tarpon




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The original "gasoline alley"




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100-year-old post office now "retired"




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Jacksonville's "treaty oak" is 300 years old




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Home of "The Tallahassee girl"




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"Dad" Gandy's "wild, visionary scheme"




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Quincy boasts first state bank




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Quaint railroad depot to be preserved




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Tragedy interrupted building of "Goodwood"




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John wanted "just a little bit of a place"




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The "state shack" bows to "executive residence"




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The sorry deal under the "treaty oak"




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James Ormond II - an "honest man"