no The Disparate Impact of Diabetes on Racial/Ethnic Minority Populations By clinical.diabetesjournals.org Published On :: 2012-07-01 Edward A. ChowJul 1, 2012; 30:130-133Diabetes Advocacy Full Article
no Plasma and Dietary Linoleic Acid and 3-Year Risk of Type 2 Diabetes After Myocardial Infarction: A Prospective Analysis in the Alpha Omega Cohort By care.diabetesjournals.org Published On :: 2020-01-20T12:00:30-08:00 OBJECTIVE To study plasma and dietary linoleic acid (LA) in relation to type 2 diabetes risk in post–myocardial infarction (MI) patients. RESEARCH DESIGN AND METHODS We included 3,257 patients aged 60–80 years (80% male) with a median time since MI of 3.5 years from the Alpha Omega Cohort and who were initially free of type 2 diabetes. At baseline (2002–2006), plasma LA was measured in cholesteryl esters, and dietary LA was estimated with a 203-item food-frequency questionnaire. Incident type 2 diabetes was ascertained through self-reported physician diagnosis and medication use. Hazard ratios (with 95% CIs) were calculated by Cox regressions, in which dietary LA isocalorically replaced the sum of saturated (SFA) and trans fatty acids (TFA). RESULTS Mean ± SD circulating and dietary LA was 50.1 ± 4.9% and 5.9 ± 2.1% energy, respectively. Plasma and dietary LA were weakly correlated (Spearman r = 0.13, P < 0.001). During a median follow-up of 41 months, 171 patients developed type 2 diabetes. Plasma LA was inversely associated with type 2 diabetes risk (quintile [Q]5 vs. Q1: 0.44 [0.26, 0.75]; per 5%: 0.73 [0.62, 0.86]). Substitution of dietary LA for SFA+TFA showed no association with type 2 diabetes risk (Q5 vs. Q1: 0.78 [0.36, 1.72]; per 5% energy: 1.18 [0.59, 2.35]). Adjustment for markers of de novo lipogenesis attenuated plasma LA associations. CONCLUSIONS In our cohort of post-MI patients, plasma LA was inversely related to type 2 diabetes risk, whereas dietary LA was not related. Further research is needed to assess whether plasma LA indicates metabolic state rather than dietary LA in these patients. Full Article
no Dietary Nonheme, Heme, and Total Iron Intake and the Risk of Diabetes in Adults: Results From the China Health and Nutrition Survey By care.diabetesjournals.org Published On :: 2020-03-20T11:50:34-07:00 OBJECTIVE Excessive iron intake has been linked to diabetes risk. However, the evidence is inconsistent. This study examined the association between dietary heme and nonheme iron intake and diabetes risk in the Chinese population. RESEARCH DESIGN AND METHODS We included 17,026 adults (8,346 men and 8,680 women) who were part of the China Health and Nutrition Survey (1991–2015) prospective cohort. Dietary intake was measured by three consecutive 24-h dietary recalls combined with a household food inventory. Diabetes cases were identified through a questionnaire. Cox proportional hazards models were used to estimate hazard ratios (HRs) and 95% CIs. RESULTS A total of 547 men and 577 women developed diabetes during 202,138 person-years of follow-up. For men, the adjusted HRs (95% CIs) for quintiles of nonheme iron intake were 1.00, 0.77 (0.58–1.02), 0.72 (0.54–0.97), 0.63 (0.46–0.85), and 0.87 (0.64–1.19) (P-nonlinearity = 0.0015). The corresponding HRs (95% CIs) for women were 1.00, 0.63 (0.48–0.84), 0.57 (0.43–0.76), 0.58 (0.43–0.77), and 0.67 (0.49–0.91) (P-nonlinearity < 0.0001). The dose-response curves for the association between nonheme iron and total iron intake and diabetes followed a reverse J shape in men and an L shape in women. No significant associations were observed between heme iron intake and diabetes risk. CONCLUSIONS Total iron and nonheme iron intake was associated with diabetes risk, following a reverse J-shaped curve in men and an L-shaped curve in women. Sufficient intake of nonheme or total iron might be protective against diabetes, while excessive iron intake might increase the risk of diabetes among men. Full Article
no Diabetic Neuropathy Is a Substantial Burden in People With Type 1 Diabetes and Is Strongly Associated With Socioeconomic Disadvantage: A Population-Representative Study From Scotland By care.diabetesjournals.org Published On :: 2020-03-20T11:50:34-07:00 OBJECTIVE To assess the contemporaneous prevalence of diabetic peripheral neuropathy (DPN) in people with type 1 diabetes (T1D) in Scotland and study its cross-sectional association with risk factors and other diabetic complications. RESEARCH DESIGN AND METHODS We analyzed data from a large representative sample of adults with T1D (N = 5,558). We assessed the presence of symptomatic neuropathy using the dichotomized (≥4) Michigan Neuropathy Screening Instrument Patient Questionnaire score. Logistic regression models were used to investigate associations between DPN and risk factors, as well as with other complications. RESULTS The burden of DPN is substantial with 13% prevalence overall. Adjusting for attained age, diabetes duration, and sex, the odds of DPN increased mainly with waist-to-hip ratio, lipids, poor glycemic control (odds ratio 1.51 [95% CI 1.21–1.89] for levels of 75 vs. 53 mmol/mol), ever versus never smoking (1.67 [1.37–2.03]), and worse renal function (1.96 [1.03–3.74] for estimated glomerular filtration rate levels <30 vs. ≥90 mL/min/1.73 m2). The odds significantly decreased with higher HDL cholesterol (0.77 [0.66–0.89] per mmol/L). Living in more deprived areas was associated with DPN (2.17 [1.78–2.65]) for more versus less deprived areas adjusted for other risk factors. Finally, individuals with prevalent DPN were much more likely than others to have other diabetes complications. CONCLUSIONS Diabetic neuropathy remains substantial, particularly affecting those in the most socioeconomically deprived groups. Those with clinically manifest neuropathy also have a higher burden of other complications and elevated levels of modifiable risk factors. These data suggest that there is considerable scope to reduce neuropathy rates and narrow the socioeconomic differential by better risk factor control. Full Article
no Man waiting to cash in $1,000 lottery ticket wins another $177,777 By www.upi.com Published On :: Fri, 08 May 2020 15:40:51 -0400 A Virginia man waiting to cash in his $1,000 winning lottery ticket ended up winning an additional $177,777 before collecting his prize. Full Article
no Influence of Dietary Protein Intake on Whole-Body Protein Turnover in Humans By care.diabetesjournals.org Published On :: 1991-12-01 Peter J GarlickDec 1, 1991; 14:1189-1198Diet and Diabetes Full Article
no The Pros and Cons of Diagnosing Diabetes With A1C By care.diabetesjournals.org Published On :: 2011-05-01 Enzo BonoraMay 1, 2011; 34:S184-S190Diabetes Full Article
no Framingham, SCORE, and DECODE Risk Equations Do Not Provide Reliable Cardiovascular Risk Estimates in Type 2 Diabetes By care.diabetesjournals.org Published On :: 2007-05-01 Ruth L. ColemanMay 1, 2007; 30:1292-1293BR Cardiovascular and Metabolic Risk Full Article
no In-Hospital Prognosis of Ppatients With Fasting Hyperglycemia After First Myocardial Infarction By care.diabetesjournals.org Published On :: 1991-08-01 John J O'SullivanAug 1, 1991; 14:758-760Short Report Full Article
no Consensus Development Conference on Insulin Resistance: 5-6 November 1997 By care.diabetesjournals.org Published On :: 1998-02-01 American Diabetes AssociationFeb 1, 1998; 21:310-314Consensus Development Conference Report Full Article
no Breaking Up Prolonged Sitting With Standing or Walking Attenuates the Postprandial Metabolic Response in Postmenopausal Women: A Randomized Acute Study By care.diabetesjournals.org Published On :: 2016-01-01 Joseph HensonJan 1, 2016; 39:130-138IDF-ADA Translational Symposium Full Article
no A Low-Glycemic Load Diet Facilitates Greater Weight Loss in Overweight Adults With High Insulin Secretion but Not in Overweight Adults With Low Insulin Secretion in the CALERIE Trial By care.diabetesjournals.org Published On :: 2005-12-01 Anastassios G. PittasDec 1, 2005; 28:2939-2941BR Clinical Care/Education/Nutrition Full Article
no Liraglutide, a Long-Acting Human Glucagon-Like Peptide-1 Analog, Given as Monotherapy Significantly Improves Glycemic Control and Lowers Body Weight Without Risk of Hypoglycemia in Patients With Type 2 Diabetes By care.diabetesjournals.org Published On :: 2007-06-01 Tina VilsbøllJun 1, 2007; 30:1608-1610BR Emerging Treatments and Technologies Full Article
no Insulinotropic Action of Glucagonlike Peptide-I-(7-37) in Diabetic and Nondiabetic Subjects By care.diabetesjournals.org Published On :: 1992-02-01 David M NathanFeb 1, 1992; 15:270-276Short Report Full Article
no Precipitation of Autoimmune Diabetes With Anti-PD-1 Immunotherapy By care.diabetesjournals.org Published On :: 2015-04-01 Jing HughesApr 1, 2015; 38:e55-e57e-Letters: Observations Full Article
no Standardizing Clinically Meaningful Outcome Measures Beyond HbA1c for Type 1 Diabetes: A Consensus Report of the American Association of Clinical Endocrinologists, the American Association of Diabetes Educators, the American Diabetes Association, the Endo By care.diabetesjournals.org Published On :: 2017-12-01 Gina AgiostratidouDec 1, 2017; 40:1622-1630Continuous Glucose Monitoring and Risk of Hypoglycemia Full Article
no Lipoprotein Physiology in Nondiabetic and Diabetic States: Relationship to Atherogenesis By care.diabetesjournals.org Published On :: 1991-09-01 Henry N GinsbergSep 1, 1991; 14:839-855Diet and Diabetes Full Article
no Undiagnosed NIDDM: Clinical and Public Health Issues By care.diabetesjournals.org Published On :: 1993-04-01 Maureen I HarrisApr 1, 1993; 16:642-652Kelly West Lecture 1992 Full Article
no Economic Costs of Diabetes in the U.S. in 2017 By care.diabetesjournals.org Published On :: 2018-05-01 American Diabetes AssociationMay 1, 2018; 41:917-928The Costs Of Diabetes Full Article
no Consensus Development Conference on the Diagnosis of Coronary Heart Disease in People With Diabetes: 10-11 February 1998, Miami, Florida By care.diabetesjournals.org Published On :: 1998-09-01 American Diabetes AssociationSep 1, 1998; 21:1551-1559Consensus Development Conference Report Full Article
no Economic Costs of Diabetes in the U.S. in 2012 By care.diabetesjournals.org Published On :: 2013-04-01 American Diabetes AssociationApr 1, 2013; 36:1033-1046Scientific Statement Full Article
no Latin American business leaders optimistic about region’s post-pandemic economy By www.upi.com Published On :: Wed, 06 May 2020 18:44:51 -0400 Despite worrying economic projections, business leaders in Latin America remain optimistic about post-pandemic economy. Full Article
no Bank of England: British economy could decline 14 percent By www.upi.com Published On :: Thu, 07 May 2020 07:29:45 -0400 A Bank of England report said Thursday the British economy could fall as much as 14 percent this year, which would be its worst showing in more than 300 years. Full Article
no Northrop Grumman awarded $123.5M to integrate Navy LAIRCM system By www.upi.com Published On :: Fri, 01 May 2020 19:14:31 -0400 Northrop Grumman received a $123.5 million contract modification Friday to integrate the Department of Navy Large Aircraft Infrared Countermeasures system onto aircraft for the U.S. military and two allied governments. Full Article
no Northrop Grumman, Raytheon partner for Next Generation Interceptor bid By www.upi.com Published On :: Mon, 04 May 2020 13:19:43 -0400 Northrop Grumman Corp. and Raytheon Missiles and Defense will partner to develop the Defense Department's next missile interceptor, they announced on Monday. Full Article
no DoD releases name of soldier who died in 'non-combat-related' incident in Iraq By www.upi.com Published On :: Tue, 05 May 2020 17:38:37 -0400 The Pentagon announced Tuesday that Sgt. Christopher Wesley Curry died Monday in Iraq in what officials describe as a non-combat-related incident. Full Article
no Memo: Prior COVID-19 diagnosis 'permanently disqualifying' for U.S. military service By www.upi.com Published On :: Thu, 07 May 2020 13:41:36 -0400 Military Entrance Processing Stations won't process individuals who have had COVID-19 for military service, even if they've fully recovered from the virus, the Pentagon confirmed this week. Full Article
no Global Economic Burden of Diabetes in Adults: Projections From 2015 to 2030 By care.diabetesjournals.org Published On :: 2018-05-01 Christian BommerMay 1, 2018; 41:963-970The Costs Of Diabetes Full Article
no PIONEER 1: Randomized Clinical Trial of the Efficacy and Safety of Oral Semaglutide Monotherapy in Comparison With Placebo in Patients With Type 2 Diabetes By care.diabetesjournals.org Published On :: 2019-09-01 Vanita R. ArodaSep 1, 2019; 42:1724-1732Emerging Therapies: Drugs and Regimens Full Article
no The Pros and Cons of Diagnosing Diabetes With A1C By care.diabetesjournals.org Published On :: 2011-05-01 Enzo BonoraMay 1, 2011; 34:S184-S190Diabetes Full Article
no Diabetes Technology Update: Use of Insulin Pumps and Continuous Glucose Monitoring in the Hospital By care.diabetesjournals.org Published On :: 2018-08-01 Guillermo E. UmpierrezAug 1, 2018; 41:1579-1589Diabetes Care Symposium Full Article
no Guideline Approach to Therapy in Patients With Newly Diagnosed Type 2 Diabetes By care.diabetesjournals.org Published On :: 2013-08-01 Itamar RazAug 1, 2013; 36:S139-S144Diabetes Pathophysiology Full Article
no Economic Costs of Diabetes in the U.S. in 2017 By care.diabetesjournals.org Published On :: 2018-05-01 American Diabetes AssociationMay 1, 2018; 41:917-928The Costs Of Diabetes Full Article
no Vasodilatory Actions of Glucagon-Like Peptide 1 Are Preserved in Skeletal and Cardiac Muscle Microvasculature but Not in Conduit Artery in Obese Humans With Vascular Insulin Resistance By care.diabetesjournals.org Published On :: 2020-02-20T11:55:30-08:00 OBJECTIVE Obesity is associated with microvascular insulin resistance, which is characterized by impaired insulin-mediated microvascular recruitment. Glucagon-like peptide 1 (GLP-1) recruits skeletal and cardiac muscle microvasculature, and this action is preserved in insulin-resistant rodents. We aimed to examine whether GLP-1 recruits microvasculature and improves the action of insulin in obese humans. RESEARCH DESIGN AND METHODS Fifteen obese adults received intravenous infusion of either saline or GLP-1 (1.2 pmol/kg/min) for 150 min with or without a euglycemic insulin clamp (1 mU/kg/min) superimposed over the last 120 min. Skeletal and cardiac muscle microvascular blood volume (MBV), flow velocity and blood flow, brachial artery diameter and blood flow, and pulse wave velocity (PWV) were determined. RESULTS Insulin failed to change MBV or flow in either skeletal or cardiac muscle, confirming the presence of microvascular insulin resistance. GLP-1 infusion alone increased MBV by ~30% and ~40% in skeletal and cardiac muscle, respectively, with no change in flow velocity, leading to a significant increase in microvascular blood flow in both skeletal and cardiac muscle. Superimposition of insulin to GLP-1 infusion did not further increase MBV or flow in either skeletal or cardiac muscle but raised the steady-state glucose infusion rate by ~20%. Insulin, GLP-1, and GLP-1 + insulin infusion did not alter brachial artery diameter and blood flow or PWV. The vasodilatory actions of GLP-1 are preserved in both skeletal and cardiac muscle microvasculature, which may contribute to improving metabolic insulin responses and cardiovascular outcomes. CONCLUSIONS In obese humans with microvascular insulin resistance, GLP-1’s vasodilatory actions are preserved in both skeletal and cardiac muscle microvasculature, which may contribute to improving metabolic insulin responses and cardiovascular outcomes. Full Article
no Time Course of Normalization of Functional {beta}-Cell Capacity in the Diabetes Remission Clinical Trial After Weight Loss in Type 2 Diabetes By care.diabetesjournals.org Published On :: 2020-03-20T11:50:34-07:00 OBJECTIVE To assess functional β-cell capacity in type 2 diabetes during 2 years of remission induced by dietary weight loss. RESEARCH DESIGN AND METHODS A Stepped Insulin Secretion Test with Arginine was used to quantify functional β-cell capacity by hyperglycemia and arginine stimulation. Thirty-nine of 57 participants initially achieved remission (HbA1c <6.5% [<48 mmol/mol] and fasting plasma glucose <7 mmol/L on no antidiabetic drug therapy) with a 16.4 ± 7.7 kg weight loss and were followed up with supportive advice on avoidance of weight regain. At 2 years, 20 participants remained in remission in the study. A nondiabetic control (NDC) group, matched for age, sex, and weight after weight loss with the intervention group, was studied once. RESULTS During remission, median (interquartile range) maximal rate of insulin secretion increased from 581 (480–811) pmol/min/m2 at baseline to 736 (542–998) pmol/min/m2 at 5 months, 942 (565–1,240) pmol/min/m2 at 12 months (P = 0.028 from baseline), and 936 (635–1,435) pmol/min/m2 at 24 months (P = 0.023 from baseline; n = 20 of 39 of those initially in remission). This was comparable to the NDC group (1,016 [857–1,507] pmol/min/m2) by 12 (P = 0.064) and 24 (P = 0.244) months. Median first-phase insulin response increased from baseline to 5 months (42 [4–67] to 107 [59–163] pmol/min/m2; P < 0.0001) and then remained stable at 12 and 24 months (110 [59–201] and 125 [65–166] pmol/min/m2, respectively; P < 0.0001 vs. baseline) but lower than that of the NDC group (250 [226–429] pmol/min/m2; P < 0.0001). CONCLUSIONS A gradual increase in assessed functional β-cell capacity occurred after weight loss, becoming similar to that of NDC group participants by 12 months. This result was unchanged at 2 years with continuing remission of type 2 diabetes. Full Article
no Inmigrantes centroamericanos en los Estados Unidos By www.migrationpolicy.org Published On :: Mon, 12 Aug 2019 12:58:39 -0400 Si bien se ha prestado mucha atención a los centroamericanos recién llegados a la frontera entre los Estados Unidos y México, casi la mitad de los aproximadamente 3.5 millones que vivían en los Estados Unidos en 2017 llegaron antes de 2000. Aproximadamente un tercio son ciudadanos estadounidenses y tienden a participar en la fuerza laboral con más frecuencia que otros extranjeros y estadounidenses. Descubra más en este artículo lleno de datos. Full Article
no International Experience Suggests Safe Third-Country Agreement Would Not Solve the U.S.-Mexico Border Crisis By www.migrationpolicy.org Published On :: Mon, 24 Jun 2019 10:44:06 -0400 While safe third-country agreements appear to hold the potential of deterring new asylum claims, experience suggests this may be a false promise. As the Trump administration explores the possibility of such agreements with Mexico and Guatemala, this commentary examines the evidence of safe third-country arrangements in Europe, finding them difficult to enforce and playing little role in deterring new claims. Full Article
no Coronavirus Is Spreading across Borders, But It Is Not a Migration Problem By www.migrationpolicy.org Published On :: Tue, 03 Mar 2020 11:52:00 -0500 Travel bans, border closures, and other migration management tools did not prove effective at blocking COVID-19 from spreading across international borders. Yet as governments have shifted from containment to mitigation with the coronavirus now in community transmission in many countries, these restrictions are a logical part of the policy toolkit in the context of social distancing and restricting all forms of human movement, as this commentary explores. Full Article
no A Proxy War on Minorities? India Crafts Citizenship and Refugee Policies through the Lens of Religion By www.migrationpolicy.org Published On :: Wed, 15 Apr 2020 21:34:32 -0400 The Modi government's push for a Citizenship Amendment Act and National Register of Citizens sparked deadly riots and chilled India's 200 million Muslims, who fear being relegated to second-class citizenship—and for some, even statelessness. This article explores actions by Modi's Bharatiya Janata Party, the significance of Bangladeshi illegal immigration as a driver, and what a register of citizens in Assam might mean for India. Full Article
no Stony Brook University opens Center for Implant and Digital Technology By www.ada.org Published On :: Thu, 02 Jan 2020 15:06:00 -0600 Stony Brook School of Dental Medicine opened Dec. 5 its Center for Implant and Digital Technology, which will serve as a state-of-the-art space for digital dentistry-focused education, patient care and research. Full Article
no ADA seeks nominations for representation on Dental Quality Alliance By www.ada.org Published On :: Fri, 10 Jan 2020 13:01:00 -0600 The ADA is calling for nominations for two seats to represent the Association in the Dental Quality Alliance. Full Article
no Dentists rank No. 2 in U.S. News & World Report’s Best Jobs report By www.ada.org Published On :: Tue, 14 Jan 2020 07:58:00 -0600 Dentists leaped up to No. 2 in U.S. News & World Report’s annual rankings of the 100 Best Jobs, the magazine revealed on its website Jan. 7. Full Article
no Nonprofit recruiting dentists to volunteer in Puerto Rico By www.ada.org Published On :: Fri, 17 Jan 2020 10:39:00 -0600 The U.S.-based International Medical Relief is sponsoring outreach trips to Puerto Rico in response to the earthquakes that have devastated the region. Full Article
no Dental schools, industry team up to create innovation centers By www.ada.org Published On :: Fri, 17 Jan 2020 10:44:00 -0600 The Center for Research & Education in Technology is encouraging dental schools to find out how to participate in its program and learn about the benefits to the school and its students. Full Article
no Member dentist honored for contributions in SNODENT development By www.ada.org Published On :: Wed, 29 Jan 2020 11:33:00 -0600 The international group SNOMED International honored ADA member dentist Dr. Mark Jurkovich with the Award of Excellence for spearheading the important work the ADA has done on SNODENT, the group announced Jan. 16. Full Article
no Missouri Dental Association notches win By www.ada.org Published On :: Mon, 03 Feb 2020 12:43:00 -0600 Thanks to the advocacy efforts of the Missouri Dental Association, a managed care organization has agreed to remove an authorization tool it was requiring dentists to use prior to using sedation. Full Article
no Indian Health Service honoring National Children’s Dental Health Month By www.ada.org Published On :: Tue, 04 Feb 2020 08:29:00 -0600 The Indian Health Service is presenting a four-part series of messages focused on their younger patients’ oral heath in honor of the February observance of National Children’s Dental Health Month. Full Article
no New HPI Industry Report now available By www.ada.org Published On :: Thu, 06 Feb 2020 11:26:00 -0600 Dental spending reached $136 billion in 2018 — 3.7% of all health spending — and what the ADA Health Policy Institute is calling a “historic high” in the new HPI Industry Report released Feb. 4. Full Article
no HIPAA fee limitation no longer applies to third-party access to health records By www.ada.org Published On :: Fri, 07 Feb 2020 16:01:00 -0600 Following a ruling in federal court two days prior, the Department of Health and Human Services announced Jan. 25 that the Health Insurance Portability and Accountability Act Privacy Rule fee limitations do not apply to requests to transmit copies of records to third-parties. Full Article
no FDA approves combination ibuprofen-acetaminophen drug for U.S. By www.ada.org Published On :: Mon, 02 Mar 2020 13:59:00 -0600 The Food and Drug Administration has approved the first over-the-counter ibuprofen and acetaminophen combination drug for the U.S. Full Article
