Wayne Gretzky’s advice to top NHL prospects: ‘Embrace every moment of it’
Five of the top NHL prospects took part in a video call with Gretzky and were given advice as they prepare to take the next step in their careers.
Five of the top NHL prospects took part in a video call with Gretzky and were given advice as they prepare to take the next step in their careers.
Old habits die hard, and for Hall of Fame goalie Gerry Cheevers, the Bruins-Canadiens rivalry manifested when Cheesy took a shot a Montreal's Carey Price during a Zoom town hall with B's season-ticket holders on Thursday.
Ruthy Hebard and Sabrina Ionescu have had a remarkable four years together in Eugene, rewriting the history books and pushing the Ducks into the national spotlight. Catch the debut of "Our Stories Unfinished Business: Sabrina Ionescu and Ruthy Hebard" at Wednesday, April 15 at 7 p.m. PT/ 8 p.m. MT on Pac-12 Network.
Bertrand Clarke, Jennifer Clarke
Source: Statist. Surv., Volume 6, 1--73.
Abstract:
We review predictive techniques from several traditional branches of statistics. Starting with prediction based on the normal model and on the empirical distribution function, we proceed to techniques for various forms of regression and classification. Then, we turn to time series, longitudinal data, and survival analysis. Our focus throughout is on the mechanics of prediction more than on the properties of predictors.
Luis Gutiérrez, Andrés F. Barrientos, Jorge González, Daniel Taylor-Rodríguez.
Source: Bayesian Analysis, Volume 14, Number 2, 649--675.
Abstract:
We propose a Bayesian nonparametric strategy to test for differences between a control group and several treatment regimes. Most of the existing tests for this type of comparison are based on the differences between location parameters. In contrast, our approach identifies differences across the entire distribution, avoids strong modeling assumptions over the distributions for each treatment, and accounts for multiple testing through the prior distribution on the space of hypotheses. The proposal is compared to other commonly used hypothesis testing procedures under simulated scenarios. Two real applications are also analyzed with the proposed methodology.
Endogenous neuropeptide Y (NPY) and corticotrophin-releasing factor (CRF) modulate the responses of the basolateral amygdala (BLA) to stress and are associated with the development of stress resilience and vulnerability, respectively. We characterized persistent effects of repeated NPY and CRF treatment on the structure and function of BLA principal neurons in a novel organotypic slice culture (OTC) model of male rat BLA, and examined the contributions of specific NPY receptor subtypes to these neural and behavioral effects. In BLA principal neurons within the OTCs, repeated NPY treatment caused persistent attenuation of excitatory input and induced dendritic hypotrophy via Y5 receptor activation; conversely, CRF increased excitatory input and induced hypertrophy of BLA principal neurons. Repeated treatment of OTCs with NPY followed by an identical treatment with CRF, or vice versa, inhibited or reversed all structural changes in OTCs. These structural responses to NPY or CRF required calcineurin or CaMKII, respectively. Finally, repeated intra-BLA injections of NPY or a Y5 receptor agonist increased social interaction, a validated behavior for anxiety, and recapitulated structural changes in BLA neurons seen in OTCs, while a Y5 receptor antagonist prevented NPY's effects both on behavior and on structure. These results implicate the Y5 receptor in the long-term, anxiolytic-like effects of NPY in the BLA, consistent with an intrinsic role in stress buffering, and highlight a remarkable mechanism by which BLA neurons may adapt to different levels of stress. Moreover, BLA OTCs offer a robust model to study mechanisms associated with resilience and vulnerability to stress in BLA.
SIGNIFICANCE STATEMENT Within the basolateral amygdala (BLA), neuropeptide Y (NPY) is associated with buffering the neural stress response induced by corticotropin releasing factor, and promoting stress resilience. We used a novel organotypic slice culture model of BLA, complemented with in vivo studies, to examine the cellular mechanisms associated with the actions of NPY. In organotypic slice cultures, repeated NPY treatment reduces the complexity of the dendritic extent of anxiogenic BLA principal neurons, making them less excitable. NPY, via activation of Y5 receptors, additionally inhibits and reverses the increases in dendritic extent and excitability induced by the stress hormone, corticotropin releasing factor. This NPY-mediated neuroplasticity indicates that resilience or vulnerability to stress may thus involve neuropeptide-mediated dendritic remodeling in BLA principal neurons.
Biodiversity for food and agriculture is among the earth’s most important resources. Biodiversity is indispensable: be it the insects that pollinate plants, the microscopic bacteria used for making cheese, the diverse livestock breeds used to make a living in harsh environments, the thousands species of fish, and other aquatic species in our lakes, rivers and oceans, or the thousands of [...]
In the year 2000, the UN Member States set the eight Millennium Development Goals. One of the most ambitious was to eradicate extreme poverty and hunger. As part of this goal, the United Nations General Assembly set a target to halve the proportion of people who suffer from hunger by 2015. But have you ever wondered how hunger is measured in [...]
Aquaponics has become all the trend. The combination of aquaculture, the practice of fish farming, and hydroponics, the cultivation of plants in water without soil, aquaponics is one example of recirculating systems generally called Integrated Aquaculture Agriculture (IAA). Some integrated farms can reduce water consumption by 90% compared to traditional agriculture. This is very good news for the agriculture sector, [...]
In 2011, declassified CIA documents shed light on a covert government program dating back to WWII
Remarkable fossil hints at the traits birds evolved just before an asteroid wiped their nonavian dinosaur kin
In its first year, the class attracted more than 1,200 students. The online version is abbreviated, but free
New research indicates that Iron Age Britons venerated brown hares and chickens long before modern Easter celebrations
A star 100-times more massive than the sun exploded with 10-times more energy than a normal-sized supernova
While COVID-19 has us homebound, it’s a good time to reflect on the peculiar histories of housewares we take for granted
The institution took decades to come to grips with the trauma of the killing of four students 50 years ago
Buenos Aires, Argentina :: Maintenance crew share Christ's love with local welders helping repair Logos Hope.
A woman who lost her sister to COVID-19 at the start of the month is thanking the staff at Northwood who took "excellent" care of her in her final days. Jean Harrigan, 90, is being remembered for her caring and lively nature.
The COVID-19 crisis has wreaked havoc on Quebec's economy, with the province recording its highest unemployment rate since at least 1976, when the data was first tracked.
On Patriots' Day, we celebrate musician, publisher, and patriot Josiah Flagg (1737-1794), a friend of Paul Revere and major figure in Early American music.
The Chicago Bulls announced Marc Eversley as their new general manager on Friday, making him the first Canadian GM in NBA history.
Happy birthday Vijay Deverakonda: Tollywood's 'Dear Comrade' who auctioned his first Filmfare Award for charity The New Indian Express
Madagascar is putting its self-proclaimed, plant-based "cure" for COVID-19 on sale and several countries in Africa have already put in orders for purchase, despite warnings from the World Health Organization that its efficacy is unproven.
Sarah Miller waited until the last minute to go buy toilet paper. When she couldn’t find any, she made a decision that she says changed her life.
Buenos Aires, Argentina :: Maintenance crew share Christ's love with local welders helping repair Logos Hope.
The post Reverse Engineering to Fix the Laser Cutter appeared first on SOLIDWORKS Education Blog.
AppleInsider has rounded up the best 16-inch MacBook Pro deals going on right now, with coupon savings knocking up to $450 off every single model. Whether you're in the market for a standard config or looking for a loaded Core i9 model, it pays to check out the cash discounts.
Amid one of the worst economic downturns in years, Apple has outperformed most expectations that analysts have placed on it. Just shy of two months into the COVID-19 pandemic, its share price has returned to levels not seen since before the crisis.
The success of Apple's AirPods line did better than the company "could ever imagine," Apple VP of product marketing Greg Joswiak claims in a profile on the audio accessories' popularity, one that also reveals extensive resources have been put into mapping ears.
Volker (OM Montenegro) describes how their outdoor lessons for Roma kids were threatened by bad weather. Then God provided not only the solution - building a carport as a shelter - but also the funds and manpower needed to build it.
Robbie and Angela from OM in Montenegro take every opportunity to bring God's love into the lives of lonely elderly people in a care home.
An outreach to the north of Madagascar was a new experience not only for those being reached, but for the participants and church as well.
Young Somali believers take bold risks in sharing their faith with their families and community.
By Father Dave Pivonka, TOR
On the afternoon of March 6, I walked around the campus of Franciscan University of Steubenville, saying goodbye to students as they headed off for Spring Break. On that cold afternoon, it was unimaginable that those students wouldn’t come back to campus to finish out the school year. It was even more unimaginable that our University, where the Mass has always been at the center of campus life, would cease the public celebration of the Eucharist.
Tragically, at Franciscan University, like everywhere else, the global spread of the coronavirus quickly made the unimaginable our new reality.
I’ve been living with that new reality for over two weeks now, and I don’t like it. So, last week, I decided to do something about it: I hung a white ribbon on the door of our University chapel.
Let me explain.
It breaks my heart to not celebrate the Mass with students, faculty, staff, and their families. I miss the singing and the filled pews, the cries of babies and the responses of the faithful. Most of all, I miss Holy Communion; I miss giving Jesus to those hungry to receive him.
I understand why our bishops and leaders made the decisions they’ve made. I’m not questioning the necessity of those decisions. Extreme social distancing, for now, is a necessary evil.
Just the same, like my brother priests everywhere, I miss my people. I long for the day we can gather again, to worship, to listen to the Word of God, to preach and to receive Jesus in the Eucharist.
Until that day comes, however, I want the men and women I serve to know that they are always with me in thought and prayer, that I’m not letting a day go by without interceding for them before God, and that I could never forget them.
Even more important, I want them to know that God could never forget them. God didn’t forget his people when they wandered in the desert for 40 years. He didn’t forget them when they worshipped idols, ignored his commands, and found themselves exiled in Babylon. And he hasn’t forgotten us now.
Make no mistake: Our Lord does not like being separated from his people in this way. Jesus wants to give himself to us. He wants us to encounter him in the liturgy, in the Church, and in the Eucharist.
And this is where the white ribbons come in.
Ribbons have long been a sign of remembrance. They tell the world that we have not forgotten someone: a prisoner, a soldier, or a sick friend. I’ve tied a white ribbon onto the door of Christ the King Chapel, as well as the Portiuncula Chapel, here at Franciscan University, to remind our community that their priests and their God have not forgotten them. I’ve invited my friends who are priests and bishops to do the same. They, in turn, are inviting more priests and bishops to join us.
My hope is that as Catholics walk or drive past their churches, they will see those white ribbons and know their priests are praying for them and waiting for the day we can fling open those doors to welcome them back inside.
I also hope, when they see those ribbons, they know Jesus is waiting for that day, too. He longs for the day when we can gather together once more, and he can be with all of us, again, in the sacraments.
That day is not yet here. Like the Israelites of old, the Catholic faithful have to wander in exile a little longer. Jesus has not left us orphans, though. He is still with us. He is with us in the Scriptures, which are his Word. He is with us in his people—those we live with, work with, or encounter online. He is with us in prayer and in silence and in the beauty of his creation, which is singing his praises as spring finally comes.
Look for Jesus in all those places. Look for Jesus where you are. And when you see white ribbons hanging from a church door, remember God’s promise in Isaiah 49:15: “I will never forget you.”
In the midst of the chaos and the confusion, and the craziness, let those ribbons be a reminder that your priests are still with you. Let them be a reminder that Jesus is still with you. And let them be a reminder that one day soon, this exile will end, the churches will re-open, and your priests will be standing there, ready and waiting to joyfully welcome you home.
A long-termer shares how she, as a childless woman, has been given opportunity to speak into local women’s lives in North Africa.
Workers encourage new believers to persevere in their faith despite facing persecution from their families.