The Fujifilm X-A7 has a big, swing-out screen, excellent color options, and capable autofocus—but no electronic viewfinder.

Saudi Arabian equities slumped on concern the U.S. may take measures against the kingdom if it’s linked to the disappearance of Washington Post writer Jamal Khashoggi.

Saudi Arabia has begun an internal investigation into the disappearance of a prominent journalist at its Istanbul consulate and could hold people accountable if the evidence warrants it, according to a Saudi official.

The heads of Deutsche Bank and Siemens, two of Germany’s biggest companies, are among a dwindling number of high-profile delegates still scheduled to attend an investment conference in Saudi Arabia following the disappearance of dissident journalist Jamal Khashoggi.

Turkish President Recep Tayyip Erdogan rejected Riyadh’s account of the killing of dissident journalist Jamal Khashoggi at Saudi Arabia’s consulate in Istanbul, saying the murder was the result of a meticulously planned plot and calling on the Saudi king to hold all culprits to account.

Penn State and the Palmer Museum of Art mourn the loss of dear friend, generous donor, and loyal champion John P. Driscoll, who died from complications due to COVID-19 on Friday, April 10. Driscoll, owner of Driscoll Babcock Galleries in New York, was a longtime friend and supporter of the Palmer Museum and will be remembered for his role as a leader, gracious mentor and trusted adviser, as well as for the expansive gifts he made to the collection and to his alma mater, Penn State.

Strategic partnerships could be used to create win-win outcomes, says Sifiso Skenjana.

A $450,000 grant from the U.S. Agency for International Development’s Feed the Future Innovation Lab for Peanut Research will aid researchers in Penn State’s College of Agricultural Sciences as they explore the potential to empower women farmers in northern Ghana through peanut production.

Gabriella Pinto provides a great example of what undergraduate research can do for a student. The Penn State food science major, who graduates this month, is headed for a good job armed with a wealth of experience and knowledge from her research, which gives her a leg up on her career.

Es ist eine einmalige Chance, die sich dieser Tage bietet: Die Veröffentlichung eines lang erwarteten Berichts der Vereinten Nationen über Verbrechen in der Demokratischen Republik Kongo (DRK) ist die Gelegenheit für eine Wiederaufarbeitung der Geschichte der massiven Gewalt im Kongo zwischen 1993 und 2003.

Of the three political upheavals that have hit the Maghreb since the beginning of 2011, the Libyan crisis seems to be the most dangerous. First of all for Libya, because the popular uprising has taken the form of an armed rebellion that has cut the country in two; second, for the West, now that NATO, under the cover of United Nations Resolution 1973 (2011) and in order to protect the civilian population, has entered the conflict on the side of the rebels, rashly gambling on a speedy war; and finally, for the region as a whole, because the conflict recently "overflowed" into Tunisia, and neighbouring countries are beginning to feel its humanitarian consequences.

La rechute est le risque majeur des pays post-conflit et l'une des principales raisons de cette rechute s'appelle la corruption.

Bacteria of the genus Campylobacter are major foodborne pathogens which have become increasingly resistant to clinically important antimicrobial agents (1)....

Mycobacterium abscessus lung infections remain difficult to treat. Recent studies have recognized the power of new combinations of antibiotics such as bedaquiline and imipenem although in vitro data have questioned this combination. We report that the efficacy of the bedaquiline plus imipenem treatment relies essentially on the activity of bedaquiline in a C3HeB/FeJ mice model of infection with a rough variant of M. abscessus. The addition of imipenem contributed at clearing the infection in the spleen.

Durlobactam (DUR, also known as ETX2514) is a novel β-lactamase inhibitor with broad activity against Ambler class A, C, and D β-lactamases. Addition of DUR to sulbactam (SUL) in vitro restores SUL activity against clinical isolates of Acinetobacter baumannii. The safety and pharmacokinetics (PK) of DUR alone and with SUL and/or imipenem/cilastatin (IMI/CIL) were evaluated in healthy subjects. This was a randomized, placebo-controlled study. In Part A, subjects including an elderly cohort (DUR 1 g) received single ascending doses of DUR 0.25-8 g. In Part B, multiple ascending dose of DUR 0.25-2 g were administered every 6 hours (q6h) for 29 doses. In Parts C and D, the drug-drug interaction (DDI) potential, including safety, of DUR (1 g) with SUL (1 g) and/or IMI/CIL (0.5/0.5 g) was investigated after single and multiple doses. Plasma and urine concentrations of DUR, SUL, and IMI/CIL were determined. Among 124 subjects, DUR was generally safe and well tolerated either alone or in combination with SUL and/or IMI/CIL. After single and multiple doses, DUR demonstrated linear dose proportional exposure across the studied dose ranges. Renal excretion was a predominant clearance mechanism. No drug:drug interaction potential was identified between DUR and SUL and/or IMI/CIL. SUL-DUR, 1 g (of each component) administered q6h with a 3 hour IV infusion, is under development for the treatment of serious infections due to A. baumannii.

The off-label use of third generation cephalosporin (3GC) during in ovo vaccination or vaccination of newly hatched chicks, was a common practice worldwide. CMY-2-producing Escherichia coli have been disseminated among broiler production. The objectives of this study were to determine the epidemiological linkage of bla_CMY-2-positive plasmids among broilers both within and outside Japan because grandparent stock and parent stock were imported in Japan. We examined the whole genome sequences of 132 3GC-resistant E. coli isolates collected from healthy broilers during 2002-2014. The predominant 3GC-resistance gene was bla_CMY-2, which was detected in the plasmids of 87 (65.9%) isolates. The main plasmid replicon types were IncI1-I (n=21; 24.1%), IncI (n=12; 13.8%), IncB/O/K/Z (n=28; 32.2%), and IncC (n=22; 25.3%). Those plasmids were subjected to gene clustering and network analyses and plasmid multi-locus sequence typing (pMLST). The chromosomal DNA of isolates was subjected to MLST and single nucleotide variant (SNV)-based phylogenetic analysis.

MLST and SNV-based phylogenetic analysis revealed high diversity of E. coli isolates. ST429 harboring bla_CMY-2-positive IncB/O/K/Z was closely related to isolates from broiler in Germany harboring bla_CMY-2-positive IncB/O/K/Z. pST55-IncI and pST12-IncI1-I and pST3-IncC were prevalent in western Japan. pST12-IncI1-I and pST3-IncC were closely related to those detected in E. coli isolates from chicken in American continent, whereas 26 IncB/O/K/Z were related to those in Europe. These data will be useful to reveal the whole picture of transmission of CMY-2-producing bacteria in and out of Japan.

'As CEO of Avast, I feel personally responsible and I would like to apologize to all concerned,' wrote Ondrej Vlcek following a PCMag-Motherboard investigation into the privacy risks around the data harvesting.

The hackers have been using files and emails that warn about a new coronavirus strain to trick users into opening them. Doing so can secretly deliver malware to the victim's machine.

Watch out for suspicious interview requests. 'The main focus of this phishing campaign was stealing email account information of the victims, and finding information about their contacts/networks,' the cybersecurity experts at Certfa Lab warned on Wednesday.

Malware on an air-gapped computer can transmit data like Morse code by changing screen brightness in a way that's invisible to the naked eye but easily recorded with a camera.

The JSE fell on Tuesday as global markets tumbled on the back of a rout in crude oil prices.

The local bourse inched higher on Wednesday as global stocks took a breather following consecutive sessions of weakness.

Local stocks advanced for a second consecutive session on Thursday as global markets remained resurgent.

The local bourse had managed to open firmer following a rally in Asian stocks in earlier trading.

Deep losses were recorded across most European benchmarks except the FTSE 100 which managed to trade relatively flat on the day.

On the currency market, the rand traded softer against the greenback as it slipped to a session low of R18.77/$.

The rand strengthened against the greenback as it peaked at a session high of R18.30 before it was recorded trading 1.41% firmer at R18.32/$ at 17.00

Lucas Tousart's first-leg goal gave Lyon a first win against Juventus, who once against face a round of 16 deficit on home soil.

Saskia perseveres through language learning and connects with a young Albanian girl who becomes a follower of Jesus.

God uses Janet to reach people through one-on-one encounters at a bookshop in a closed country.

With speed and ingenuity, more than 100 researchers across Penn State are shifting their research programs to address the COVID-19 crisis, thanks to funding from a seed grant initiative led by the Huck Institutes of the Life Sciences. In total, the initiative awarded $2.25 million to 47 teams of researchers from three campuses, 10 colleges and more than 25 departments.

Penn State Health Milton S. Hershey Medical Center has begun enrolling participants in an international clinical trial evaluating an investigational antiviral drug, remdesivir, for treatment of coronavirus disease 2019 (COVID-19).

The Penn State Center for Structural Oncology is shifting some of its focus from fighting cancer to fighting COVID-19, with three projects.

Credit card fraud increased to 19.47% as at the end of March 2019, compared to 12.2% reported at the beginning of January 2019.

Millicent Collins
Aug 1, 2017; 140:e20160719-e20160719
CASE REPORTS

A winner of the European Women's Under-17 Championship with Poland in 2013, Ewa Pajor urges the players taking part in this year's final tournament in Bulgaria to seize the moment.

Are you sure you know what the "insurance speak" in your policy means?

Interest in Section 12J has grown each year, with the current financial year being no different, says Jonty Sacks, a partner at Jaltech.

Many investors do not fully understand the tax incentive and structure of a Section 12J venture capital investment, according to a managing director involved in this sector.

By the end of February, most taxpayers are looking for every opportunity to reduce their tax liabilities.

The coronavirus closures are shaping a disruptive end to a tumultuous academic career for the Class of 2020.

A signature program at Penn State Greater Allegheny, implemented to give students, faculty and staff the digital skills to communicate, solve problems and create new knowledge, is front and center in the University’s remote learning period.

Ebonie Slade, a senior majoring in biobehavioral health at Penn State Greater Allegheny, is the recipient of the 2020 Jackson Lethbridge Tolerance Award.

Saskia perseveres through language learning and connects with a young Albanian girl who becomes a follower of Jesus.