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Annual Tropical Fish Show Set For Tomorrow

The Bermuda Fry-Angle Aquarium Society will hold its annual Tropical Fish Show tomorrow [Nov 16] from 10.00am to 4.00pm at the First Baptist Church in Devonshire. The event poster says, “Come and see Bermuda’s most beautiful and unusual fish on display and in competition. “Show your own best fish. Entry forms are available on fryangle.com […]

(Click to read the full article)




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BIFF To Screen ‘The White Crow’ On December 4

The Bermuda International Film Festival [BIFF] is to screen a dramatic film about ballet legend Rudolf Nureyev at its monthly film series, BIFFFlix. In 1961, a dazzling Nureyev travelled to Paris as a member of the world-renowned Kirov Ballet Company. Outside the Soviet Union for the first time, Parisian life delights Nureyev and the young […]

(Click to read the full article)




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Debris Thrown In Ocean Harming Sea Turtles

[Written by Don Burgess] Residents are being urged not to throw debris into the ocean after another sea turtle was found dead recently. Two swimmers near the channel off of Dockyard recently found a turtle floating dead in the water. The animal had become entangled in fishing line and strangled to death. At the end of […]

(Click to read the full article)




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Rowdy Piper’s New Soca Music Video “Crossfit”

Bermudian artist Rowdy Piper has released a new video for his energetic soca single ‘Crossfit,’ which was filmed at the Crossfit BDA gym by Near Future Media. A spokesperson said, “The video is a workout-inspired romp through soca fitness, celebrating summer bodies of all shapes and sizes. “Rowdy Piper, also known as R?ddla [or Roddy […]

(Click to read the full article)




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Fidelis Appoints Daniel Burrows & Ian Burford

Fidelis Insurance announced that founder member Daniel Burrows has been promoted to Group Managing Director for the Fidelis Group and Ian Burford has been appointed to Chief Executive Officer for Fidelis Underwriting Limited [FUL]. Burrows joined Fidelis in 2015 and previously was co-CEO of AonBenfield’s Global ReSpeciality [GRS] division. Burford has over 30 years’ experience […]

(Click to read the full article)




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Argus Group Appoints David Brown As Director

In a filing with the Bermuda Stock Exchange [BSX], Argus Group Holdings Limited [Argus Group] announced the appointment as a Director of Mr. David A Brown with effect from February 10, 2020. Related Stories Argus Announces Retirement Of Steinhoff Argus Appoints Simmons As Director Argus Group Reports Net Profit Of $8.2 Million Argus CFO Retires: […]

(Click to read the full article)




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Photos & Video: Home-Grown Alternatives Show

The Home-Grown Alternatives Show was held on Saturday [Dec 7] at the St. Paul’s Christian Centre on Middle Road in Paget, with vendors offering a shopping experience designed to showcase Bermuda-made arts and crafts. Live video replay below: In 1995 Christine Wellman and Mary Tatem decided to hold a pre-Christmas craft fair, and over the years the […]

(Click to read the full article)




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Video: Pan Am Athlete Profile Of Noah Browne

In the thirteenth of a series of video profiles of the athletes set to represent Bermuda at the upcoming 2019 Pan Am Games in Lima, Peru, meet Noah Browne, who will be competing in squash. The Pan American Games are the world’s third largest international sporting festival, and will run from 26 July to 11 […]

(Click to read the full article)




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Noah Browne Advances In Nash Cup In Canada

Noah Browne recently began competing in the $12,000 Men’s NASH Squash Cup 2019, taking place at the London Squash & Fitness in London, Ontario, Canada. Browne advanced to the second round after defeating his first round opponent Charles de la Riva from Canada. Browne eased to victory in 26 minutes, winning 11-8, 11-2, 11-7. Related […]

(Click to read the full article)




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Noah Browne Falls In Nash Cup Second Round

Noah Browne recently continued competing in the $12,000 Men’s NASH Squash Cup 2019, taking place at the London Squash & Fitness in London, Ontario, Canada. Browne went down in his second round match when he took on the eighth seed Cameron Seth from Canada. Browne fell in straight sets 11-4, 11-8, 11-6 in 37 minutes. […]

(Click to read the full article)




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Noah Browne Advances In Wakefield Open

Noah Browne recently began competing in the $6,000 Men’s Wakefield Open 2019 in Virginia. Browne, ranked fifth, took on Reuben Phillips from England in the first round. Browne advanced in a four game battle, winning 11-6, 11-2, 7-11, 11-5. Related Stories Photos, Videos & Results: Squash Finals Photos & Results: AXIS Squash Challenge Day 1 […]

(Click to read the full article)




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Browne Falls in Wakefield Open Quarter-Finals

Noah Browne recently continued competing in the $6,000 Men’s Wakefield Open 2019 in Virginia. Browne, ranked fifth, took on Mohamed Nabil from Egypt in the quarter-finals. Browne fell in a five game battle; Browne won the first match 11-7, but Nabil leveled the match at 1-1 when he won game two 11-9. Browne went back […]

(Click to read the full article)




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Browne Advances In Cleveland Squash Open

Noah Browne recently began competing in the $20,000 Men’s Cleveland Skating Club Squash Open, taking place in Cleveland, Ohio. In his first round match, Browne took on Arshad Iqbal Burki from Pakistan in a match that lasted three sets. Browne advanced to the second round after defeating Burki in straight games that took 22 minutes, […]

(Click to read the full article)




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Court: Man Admits Throwing Corrosive Liquid

[Written by Don Burgess] A man who had a standoff with police pleaded guilty to multiple charges related to that incident, including four counts of throwing a corrosive liquid at officers. James Dallas, 70, was involved in a seven-hour standoff with police on March 28, 2019 on Happy Valley Road in Pembroke. Mr Dallas pleaded guilty to […]

(Click to read the full article)




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Bermuda Festival Tickets Go On Sale Tomorrow

Tickets for the 2015 Bermuda Festival will be available for purchase beginning tomorrow [Nov 25] at 10.00am. The Bermuda Festival is honouring their 40th anniversary with an amazing line-up of talented local and international performers, with 19 events to choose from including jazz, classical, opera, theatre, and even disco. The events start on January 23rd, […]

(Click to read the full article)




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WEDCO: Two Options For Albert Row Property

“For more than 15 years WEDCO has been searching both internally and externally for a solution which would see the restoration of Albert Row,” WEDCO said, explaining that they are still hopeful someone will come forward with a “workable solution,” however if not the only two options are to leave them in a derelict condition or […]

(Click to read the full article)




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DictionaryPro Browser Hijacker

DictionaryPro browser hijacker removal instructions

What is DictionaryPro?

DictionaryPro is a piece of software, categorized as a browser hijacker. It is endorsed as a tool for easy access to online dictionaries, spell checking and grammar websites. It operates by altering browser settings in order to promote dictionarypro.co - an illegitimate search engine. Additionally, this browser hijacker spies on users' browsing activity. Furthermore, due to its dubious proliferation method, DictionaryPro is also deemed to be a PUA (Potentially Unwanted Application). Users should note that DictionaryPro often promotes another browser hijacker called Protect My Search Daily.




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Download Apps Now Browser Hijacker

Download Apps Now browser hijacker removal instructions

What is Download Apps Now?

Download Apps Now is a rogue application, categorized as a browser hijacker. It is endorsed as an easy access tool to a variety of content. For example, to popular email providers as well as weather, news and video streaming websites. This app operates by modifying browsers in order to promote hdownloadappsnow.app - a fake search engine. Most browser hijackers are able to track browsing-related data, and it is highly likely that Download Apps Now possesses such abilities as well. Since most users download/install it inadvertently, it is also deemed to be a PUA (Potentially Unwanted Application).




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Find Local Classifieds Browser Hijacker

Find Local Classifieds browser hijacker removal instructions

What is Find Local Classifieds?

Find Local Classifieds browser hijacker is designed to promote the findlocalclassifiedstab.com address, a fake search engine. Like most apps of this type, it promotes it by changing certain browser's settings. Usually, browser hijackers not only modify settings but also collect various (mostly browsing-related) information. Since users often download and install apps like Find Local Classifieds unintentionally, unknowingly, they are categorized as potentially unwanted applications (PUAs).




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CapitaSearch Browser Hijacker

CapitaSearch browser hijacker removal instructions

What is CapitaSearch?

CapitaSearch is a piece of software, classified as a browser hijacker. Following successful infiltration, it modifies browser settings in order to promote search.capita.space - a fake search engine. Additionally, CapitaSearch adds the "Managed by your organization" feature to Google Chrome browsers. Most browser hijackers spy on browsing activity. Since most users download/install CapitaSearch unintentionally, it is also considered to be a PUA (Potentially Unwanted Application). One of the dubious methods used to distribute CapitaSearch is via illegal software activation ("cracking") tools. It is noteworthy that these tools are often used to proliferate malicious content as well (e.g. ransomware, trojans and other malware).




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Teen Launches "A Meal Today, A Meal Tomorrow" Program

Chicago high school junior Jessica Tansey was concerned about her classmates whose families would struggle with food insecurity during the school closure for COVID-19. At the same time, she was concerned about the restaurants in her neighborhood and the negative effect the COVID-19 shutdowns were having on them. She came up with and launched a campaign called “A Meal Today, A Meal Tomorrow” to help with both community issues.

It works by a customer buying one gift card at a nearby restaurant, and the restaurant agreeing to donate a second gift card to Tansey’s high school, which is then given to a school family in need. While some of the larger restaurant chains are able to commit to matching gift cards dollar-for-dollar, many smaller restaurants are donating gift cards worth a percentage of the one purchased to help out. Tansey said, “If we can connect restaurants and students with one solution, maybe it can make a difference for everybody. I want to get all of us thinking about how to bring communities together to support each other during rough times.”




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Particle Physics Turns to Quantum Computing for Solutions to Tomorrow's Big-Data Problems

Giant-scale physics experiments are increasingly reliant on big data and complex algorithms fed into powerful computers, and managing this multiplying mass of data presents its own unique challenges. To better prepare for this data deluge posed by next-generation upgrades and new experiments, physicists are turning to the fledgling field of quantum computing.




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Dysfunctional Families: Growing Wings

It's been a long time since I've posted a new entry to this community, and I know the comments on...




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HCL finishes its year with 15 percent growth, 100 million minutes-a-month Teams usage

Cracks the 150,000-employee mark as revenue falls just short of $10bn

Indian services giant HCL Technologies has wound up its 19/20 financial year by reporting 15 percent annual growth but a flat Q4.…




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FYI: Your browser can pick up ultrasonic signals you can't hear, and that sounds like a privacy nightmare to some

High-frequency audio could be used to stealthily track netizens

Technical folks looking to improve web privacy haven't been able to decide whether sound beyond the range of human hearing poses enough of a privacy risk to merit restriction.…




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11/10/13 - Five nights in a row




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11/17/13 - Don't understand grownups




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05/01/16 - Your lips have grown so cold




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Stop Throwing Away Those Little Silica Gel Packets! You and the Kids Can Use Them a Ton of Clever Ways

Parents, kids: Fear not the silica gel pack. Sure it says DO NOT EAT and THROW AWAY. But you should only follow one of those rules.    Instead, save the packs and use them a whole lot of ways: Place them on the car dashboard by the windshield to keep it from fogging up.   […]




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Retrograde nerve growth factor signaling abnormalities in familial dysautonomia

Familial dysautonomia (FD) is the most prevalent form of hereditary sensory and autonomic neuropathy (HSAN). In FD, a germline mutation in the Elp1 gene leads to Elp1 protein decrease that causes sympathetic neuron death and sympathetic nervous system dysfunction (dysautonomia). Elp1 is best known as a scaffolding protein within the nuclear hetero-hexameric transcriptional Elongator protein complex, but how it functions in sympathetic neuron survival is very poorly understood. Here, we identified a cytoplasmic function for Elp1 in sympathetic neurons that was essential for retrograde nerve growth factor (NGF) signaling and neuron target tissue innervation and survival. Elp1 was found to bind to internalized TrkA receptors in an NGF-dependent manner, where it was essential for maintaining TrkA receptor phosphorylation (activation) by regulating PTPN6 (Shp1) phosphatase activity within the signaling complex. In the absence of Elp1, Shp1 was hyperactivated, leading to premature TrkA receptor dephosphorylation, which resulted in retrograde signaling failure and neuron death. Inhibiting Shp1 phosphatase activity in the absence of Elp1 rescued NGF-dependent retrograde signaling, and in an animal model of FD it rescued abnormal sympathetic target tissue innervation. These results suggest that regulation of retrograde NGF signaling in sympathetic neurons by Elp1 may explain sympathetic neuron loss and physiologic dysautonomia in patients with FD.




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(H)Elping nerve growth factor: Elp1 inhibits TrkA’s phosphatase to maintain retrograde signaling

Nerve growth factor (NGF) regulates many aspects of neuronal biology by retrogradely propagating signals along axons to the targets of those axons. How this occurs when axons contain a plethora of proteins that can silence those signals has long perplexed the neurotrophin field. In this issue of the JCI, Li et al. suggest an answer to this vexing problem, while exploring why the Elp1 gene that is mutated in familial dysautonomia (FD) causes peripheral neuropathy. They describe a distinctive function of Elp1 as a protein that is required to sustain NGF signaling by blocking the activity of its phosphatase that shuts off those signals. This finding helps explain the innervation deficits prominent in FD and reveals a unique role for Elp1 in the regulation of NGF-dependent TrkA activity.




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Chronic mirabegron treatment increases human brown fat, HDL cholesterol, and insulin sensitivity

BACKGROUND Mirabegron is a β3-adrenergic receptor (β3-AR) agonist approved only for the treatment of overactive bladder. Encouraging preclinical results suggest that β3-AR agonists could also improve obesity-related metabolic disease by increasing brown adipose tissue (BAT) thermogenesis, white adipose tissue (WAT) lipolysis, and insulin sensitivity.METHODS We treated 14 healthy women of diverse ethnicities (27.5 ± 1.1 years of age, BMI of 25.4 ± 1.2 kg/m2) with 100 mg mirabegron (Myrbetriq extended-release tablet, Astellas Pharma) for 4 weeks in an open-label study. The primary endpoint was the change in BAT metabolic activity as measured by [18F]-2-fluoro-d-2-deoxy-d-glucose (18F-FDG) PET/CT. Secondary endpoints included resting energy expenditure (REE), plasma metabolites, and glucose and insulin metabolism as assessed by a frequently sampled intravenous glucose tolerance test.RESULTS Chronic mirabegron therapy increased BAT metabolic activity. Whole-body REE was higher, without changes in body weight or composition. Additionally, there were elevations in plasma levels of the beneficial lipoprotein biomarkers HDL and ApoA1, as well as total bile acids. Adiponectin, a WAT-derived hormone that has antidiabetic and antiinflammatory capabilities, increased with acute treatment and was 35% higher upon completion of the study. Finally, an intravenous glucose tolerance test revealed higher insulin sensitivity, glucose effectiveness, and insulin secretion.CONCLUSION These findings indicate that human BAT metabolic activity can be increased after chronic pharmacological stimulation with mirabegron and support the investigation of β3-AR agonists as a treatment for metabolic disease.TRIAL REGISTRATION Clinicaltrials.gov NCT03049462.FUNDING This work was supported by grants from the Intramural Research Program of the NIDDK, NIH (DK075112, DK075116, DK071013, and DK071014).





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MacRumors Giveaway: Win an Apple-Themed Plush Pillow From Throwboy

For this week's giveaway, we've once again teamed up with Throwboy to offer MacRumors readers a chance to win one of Throwboy's plushes modeled after classic Apple products and icons.


Throwboy makes a whole range of different plush pillow options priced at $30 to $40, with each one designed to look like an Apple product of some kind, including classic Macs, the iPod, the iPhone, and more. Each pillow features detailed embroidery and careful construction to highlight each component and to accurately represent Apple's designs.

The 1998 pillow, for example, is modeled after Apple's original iMac with its bright Bondi Blue design, while the 2001 pillow modeled after the original iPod comes complete with a screen and click wheel embroidery.


The 2007 pillow looks like the original ‌iPhone‌ with black bezels and a silver backing, and the Icon Pillow looks like Apple's classic happy Finder icon.


There's even a rainbow-colored Spinning Wheel Pillow that's designed to look like the dreaded spinning pinwheel that the cursor morphs into when an application is busy.


All of Throwboy's plushes are soft, squishy, huggable, and the perfect accent piece for an Apple fan. Each pillow is the ideal size to be used as a comfortable throw pillow for a couch or a chair. Photos of the pillows in action can be seen on Throwboy's Instagram account.


We have 10 of Throwboy's pillows to give away to MacRumors readers, and each winner will be able to pick their favorite pillow: ‌iMac‌, iPod, classic ‌iPhone‌, Finder Icon, or Spinning Wheel.

To enter to win our ‌giveaway‌, use the Gleam.io widget below and enter an email address. Email addresses will be used solely for contact purposes to reach the winners and send the prizes. You can earn additional entries by subscribing to our weekly newsletter, subscribing to our YouTube channel, following us on Twitter, following us on Instagram, or visiting the MacRumors Facebook page.

Due to the complexities of international laws regarding giveaways, only U.S. residents who are 18 years or older and Canadian residents (excluding Quebec) who have reached the age of majority in their province or territory are eligible to enter. To offer feedback or get more information on the ‌giveaway‌ restrictions, please refer to our Site Feedback section, as that is where discussion of the rules will be redirected.

Throwboy Giveaway
The contest will run from today (May 8) at 11:00 a.m. Pacific Time through 11:00 a.m. Pacific Time on May 15. The winners will be chosen randomly on May 15 and will be contacted by email. The winners will have 48 hours to respond and provide a shipping address before new winners are chosen.
This article, "MacRumors Giveaway: Win an Apple-Themed Plush Pillow From Throwboy" first appeared on MacRumors.com

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Erowid Experience Reports - May 01 2020

New experience reports published by Erowid on May 01 2020




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Erowid Experience Reports - May 02 2020

New experience reports published by Erowid on May 02 2020




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Erowid Experience Reports - May 04 2020

New experience reports published by Erowid on May 04 2020




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Erowid Experience Reports - May 05 2020

New experience reports published by Erowid on May 05 2020




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Erowid Experience Reports - May 06 2020

New experience reports published by Erowid on May 06 2020




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Erowid Experience Reports - May 08 2020

New experience reports published by Erowid on May 08 2020




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Bob Stefanowski will make Sam Brownback look like a socialist in comparison by eliminating the income tax in Connecticut

NEWS 8 IS YOUR LOCAL ELECTION HEADQUARTERS…. AND TONIGHT…VOODOO ECONOMICS! CHIEF POLITICAL CORRESPONDENT MARK DAVIS TELLING US HOW REPEALING THE STATE INCOME TAX IS THE LATEST HEATED TOPIC BETWEEN THE CANIDATES FOR GOVERNOR.   DEMOCRAT NED LAMONT IS OPENING A … Continue reading




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Linux on IBM Power Systems Beats Market Growth Performance by 3X

IBM today announced that according to results from International Data Corporation (IDC) Worldwide Quarterly Server Tracker®(June, 2017) IBM has achieved market growth by 3x compared with the total Linux server market which grew at +6 percent. The improved performance are the result of success across IBM Power Systems including IBM’s OpenPOWER LC servers and IBM Power Systems running SAP HANA as well as the OpenPOWER-Ready servers developed through the OpenPOWER Foundation.




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Acrow Formwork & Scaffolding selects IBM Cloud and Mobile platforms for IT Refresh

IBM announced today that Acrow, one of Australia’s leading suppliers of scaffolding and formwork for the construction industry, has selected IBM and IT Easy , to implement a total infrastructure refresh built around IBM Cloud, mobile, and network technology.




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IBM Builds On Growing Social Business Momentum with New Clients and Services

IBM today announced continuing momentum for its social business offerings with clients around the world ushering in the next era of collaboration with IBM Verse and Connections. IBM also announced expanded capabilities in its collaboration portfolio with new innovations that make it easier for clients to gain and share business insights across teams.



  • IBM Social Business

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Crown apoyará su expansión en México con Servicios de TI y Nube híbrida de IBM

IBM y Crown Holdings, Inc., proveedor global líder en productos de empaques metálicos, anunciaron hoy la firma de un contrato de varios años que incluye servicios de TI y servicios administrados corriendo en la robusta plataforma de cómputo en la nube de clase empresarial de IBM.



  • Services and solutions

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IBM Safeguards Mobile Devices at Arrow International

IBM has implemented a cloud-based enterprise mobility management and security solution at Arrow International.




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IBM Storage Supports Rakon’s International Growth

Rakon has selected the IBM Storwize V7000 SAN as part of a strategic storage upgrade to meet the needs of its rapidly expanding international quartz crystal manufacturing business.




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Bendigo and Adelaide Bank adopts next-gen storage systems for customer service growth

IBM (NYSE: IBM) today announced that Bendigo and Adelaide Bank has selected IBM XIV Storage System Gen3 as a key infrastructure component for its ongoing development and delivery of customer-focussed business applications.