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What's In Store @ MO'BETA BODEGA



The MO'BETA BODEGA is where it's at!




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What's In Store @ MO'BETA BODEGA



The MO'BETA BODEGA is where it's at!




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Flexin' At The Mo' BETA Bodega!



Swag is all you need in the Mo' BETA Bodega!




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Alicia Keys Details Finding Herself In New Book



“I realized that my whole life I’ve been putting on a mask.”




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Rihanna Just Gave A Detailed Update On New Music



She also addresses reggae-inspired album rumors.





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LeBron James Reveals New Details On "Space Jam" Sequel



The countdown is on.





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Feds Fail To Get Retail Coronavirus Tests To Black People



Only eight of 63 slated sites are in African American areas




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Comment on Earth Day Turns 50 with a Massive Livestream Event by dipercetakan

The above article is nice and interesting, thank you willing to share! :)




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Esso Retail Service Station Holiday Hours

Esso Service Station is advising the public of their hours of operation effective today [April 9] as well as for Good Friday [April 10]. Esso station hours of operation [April 9]: Station Open AM Close PM Sandy’s 7.00 7.00 Port Royal 7.00 7.00 Warwick 8.00 6.00 BIU [Mon - Sat] 7.00 6.00 BIU [SUN] 7.00 […]

(Click to read the full article)




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Photos & Video: ETA Motorcycles Tour Bermuda

After ten years of travelling to Bermuda on board different cruise ships and according to President of ETA Motorcycle Cruises Steve Wallach, over three thousand bikes making the journey, another group including Police Officers from Essex County, landed on our shores today [May 11] for a two day visit. The Bermuda Long Riders Motorcycle Club […]

(Click to read the full article)




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Adam Hall’s Delmarva Retain Governor’s Cup

Adam Hall and the Delmarva Shorebirds baseball team retained the Governors’ Cup as they defeated the Hagerstown Suns 4-2. The club’s report said, “The Delmarva Shorebirds clinched the Governors’ Cup for the second consecutive year as they downed the Hagerstown Suns 4-2 on Friday night at Arthur W. Perdue Stadium. “Nick Vespi [5-4] collected the win […]

(Click to read the full article)




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Bermuda Retains Jumping Challenge Title

The 2019 Caribbean Equestrian Association’s Regional Jumping Challenge [CEA RJC] recently came to a successful conclusion for Bermuda’s show jumping riders. A spokesperson said, “For the fourth consecutive year, the Bermuda team has secured the top place against other participating Caribbean countries. “In addition to winning the Team Country division, Bermuda riders also captured the […]

(Click to read the full article)




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Minister Provides Unemployment Benefit Details

[Updated with video] The Unemployment Benefit will be for eligible employees not currently on Financial Assistance and provide a payment of 60% of their gross earnings up to a maximum of $500 per week, and employees eligible must meet the definition of an employee under the Employment Act 2000 and be either Bermudian, spouse of […]

(Click to read the full article)




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Court: Shaketa Raynor Jailed In England

44-year-old Shaketa Raynor has reportedly been jailed for four years in the UK after being caught trying to smuggle cocaine. This is according to a report by the HullLive, which said, “Croydon Crown Court heard on Monday that Shaketa Raynor, 44, was found with over four kilogrammes of the Class A drug in her suitcase after […]

(Click to read the full article)




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Garrett: The Drumhead Also A Metaphor For AIDS

Spencer Garrett, who portrayed Simon Tarses in The Next Generation: The Drumhead episode, spoke to StarTrek.com about getting the role, what the...




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pretaliation




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Monitoring Intermediates in CO2 Conversion to Formate by Metal Catalyst

The production of formate from CO2 is considered an attractive strategy for the long-term storage of solar renewable energy in chemical form.




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Вышла iOS 13.5 beta 4 для разработчиков. Что нового

Время обновляться.




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Targetable ERBB2 mutations identified in neurofibroma/schwannoma hybrid nerve sheath tumors

BACKGROUND Neurofibroma/schwannoma hybrid nerve sheath tumors (N/S HNSTs) are neoplasms associated with larger nerves that occur sporadically and in the context of schwannomatosis or neurofibromatosis type 2 or 1. Clinical management of N/S HNSTs is challenging, especially for large tumors, and established systemic treatments are lacking.METHODS We used next-generation sequencing and array-based DNA methylation profiling to determine the clinically actionable genomic and epigenomic landscapes of N/S HNSTs.RESULTS Whole-exome sequencing within a precision oncology program identified an activating mutation (p.Asp769Tyr) in the catalytic domain of the ERBB2 receptor tyrosine kinase in a patient with schwannomatosis-associated N/S HNST, and targeted treatment with the small-molecule ERBB inhibitor lapatinib led to prolonged clinical benefit and a lasting radiographic and metabolic response. Analysis of a multicenter validation cohort revealed recurrent ERBB2 mutations (p.Leu755Ser, p.Asp769Tyr, p.Val777Leu) in N/S HNSTs occurring in patients who met diagnostic criteria for sporadic schwannomatosis (3 of 7 patients), but not in N/S HNSTs arising in the context of neurofibromatosis (6 patients) or outside a tumor syndrome (1 patient), and showed that ERBB2-mutant N/S HNSTs cluster in a distinct subgroup of peripheral nerve sheath tumors based on genome-wide DNA methylation patterns.CONCLUSION These findings uncover a key biological feature of N/S HNSTs that may have important diagnostic and therapeutic implications.FUNDING This work was supported by grant H021 from DKFZ-HIPO, the University Cancer Center Frankfurt, and the Frankfurt Research Funding Clinician Scientist Program.




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Parental metabolic syndrome epigenetically reprograms offspring hepatic lipid metabolism in mice

The prevalence of nonalcoholic fatty liver disease (NAFLD) is increasing worldwide. Although gene-environment interactions have been implicated in the etiology of several disorders, the impact of paternal and/or maternal metabolic syndrome on the clinical phenotypes of offspring and the underlying genetic and epigenetic contributors of NAFLD have not been fully explored. To this end, we used the liver-specific insulin receptor knockout (LIRKO) mouse, a unique nondietary model manifesting 3 hallmarks that confer high risk for the development of NAFLD: hyperglycemia, insulin resistance, and dyslipidemia. We report that parental metabolic syndrome epigenetically reprograms members of the TGF-β family, including neuronal regeneration–related protein (NREP) and growth differentiation factor 15 (GDF15). NREP and GDF15 modulate the expression of several genes involved in the regulation of hepatic lipid metabolism. In particular, NREP downregulation increases the protein abundance of 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) and ATP-citrate lyase (ACLY) in a TGF-β receptor/PI3K/protein kinase B–dependent manner, to regulate hepatic acetyl-CoA and cholesterol synthesis. Reduced hepatic expression of NREP in patients with NAFLD and substantial correlations between low serum NREP levels and the presence of steatosis and nonalcoholic steatohepatitis highlight the clinical translational relevance of our findings in the context of recent preclinical trials implicating ACLY in NAFLD progression.




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Fetal alcohol spectrum disorder predisposes to metabolic abnormalities in adulthood

Prenatal alcohol exposure (PAE) affects at least 10% of newborns globally and leads to the development of fetal alcohol spectrum disorders (FASDs). Despite its high incidence, there is no consensus on the implications of PAE on metabolic disease risk in adults. Here, we describe a cohort of adults with FASDs that had an increased incidence of metabolic abnormalities, including type 2 diabetes, low HDL, high triglycerides, and female-specific overweight and obesity. Using a zebrafish model for PAE, we performed population studies to elucidate the metabolic disease seen in the clinical cohort. Embryonic alcohol exposure (EAE) in male zebrafish increased the propensity for diet-induced obesity and fasting hyperglycemia in adulthood. We identified several consequences of EAE that may contribute to these phenotypes, including a reduction in adult locomotor activity, alterations in visceral adipose tissue and hepatic development, and persistent diet-responsive transcriptional changes. Taken together, our findings define metabolic vulnerabilities due to EAE and provide evidence that behavioral changes and primary organ dysfunction contribute to resultant metabolic abnormalities.




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Mature myelin maintenance requires Qki to coactivate PPARβ-RXRα–mediated lipid metabolism

Lipid-rich myelin forms electrically insulating, axon-wrapping multilayers that are essential for neural function, and mature myelin is traditionally considered metabolically inert. Surprisingly, we discovered that mature myelin lipids undergo rapid turnover, and quaking (Qki) is a major regulator of myelin lipid homeostasis. Oligodendrocyte-specific Qki depletion, without affecting oligodendrocyte survival, resulted in rapid demyelination, within 1 week, and gradually neurological deficits in adult mice. Myelin lipids, especially the monounsaturated fatty acids and very-long-chain fatty acids, were dramatically reduced by Qki depletion, whereas the major myelin proteins remained intact, and the demyelinating phenotypes of Qki-depleted mice were alleviated by a high-fat diet. Mechanistically, Qki serves as a coactivator of the PPARβ-RXRα complex, which controls the transcription of lipid-metabolism genes, particularly those involved in fatty acid desaturation and elongation. Treatment of Qki-depleted mice with PPARβ/RXR agonists significantly alleviated neurological disability and extended survival durations. Furthermore, a subset of lesions from patients with primary progressive multiple sclerosis were characterized by preferential reductions in myelin lipid contents, activities of various lipid metabolism pathways, and expression level of QKI-5 in human oligodendrocytes. Together, our results demonstrate that continuous lipid synthesis is indispensable for mature myelin maintenance and highlight an underappreciated role of lipid metabolism in demyelinating diseases.




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We Visited a Masonic Cemetary

You read that right. Joanne and I visited a Masonic Cemetary. Alone. It was one of the most calming experiences of my life. We were kind of invited, by the town, and when we arrived, we were definitely welcomed by the residents. This all started when, in the brochure listing the “town attractions” that we received in St. Helens, were two cemeteries. The addresses as well as short descriptions were listed, as well as a short missive asking us to please be respectful and not make loud noises. It sounded really creepy and really interesting, so both of us jumped at the chance to drive out there right before sunset. They weren’t what I expected at all… Well, the first one was actually roped off with a “no trespassing” sign hanging from it, so we didn’t go inside. It was right alongside the highway in Oregon, across some old train tracks, visible from the road, and named and marked on a tourist map, yet they didn’t want visitors. I wonder what happened there. In any case, we headed for the other cemetery. This one was removed from the main road, and rumored to be a lot larger. It was also known to be haunted, but visitors were welcome as long as they were respectful. Off the map it was, but when we arrived, it was also gated off. A sad Joanne looks through the gate at the second destination that was cut off from us. Ah, but unlike the other cemetery, this one didn’t have a “no tresspassing” sign. There was a clear path around the sides of the gate, the ground bare of grass and obviously well-traversed. Apparently a lot of people walked around the gate. Maybe they just didn’t want us to drive. We decided to walk. There was even a sign. And a long, winding, steep road through the forest.  It was quite a hike to reach the top of the large hill where the cemetery was supposedly located, but the view was breathtaking. It took us a good ten or fifteen minutes to reach the top, and the road was quite steep. For some reason, to the immediate right of the trail, someone had been excavating land for quite some time, and there was a deep quarry. Why someone would dig a quarry next to a burial ground is beside me. I don’t doubt that the residents were unhappy about it. I wondered if maybe I would feel some spirits, but I didn’t expect what really happened to me. As soon as I stepped off of the road and onto the grass, a calm unlike anything I’ve ever felt descended upon me. It enveloped me in a warm cocoon, and Joanne and I immediately separated and wandered quietly alone between the gravestones. I know, 100%, that not only was I welcomed, but that the residents were happy to have me there. I talked a bit with some of the gravestones, but mostly wandered about, amazed at how much serenity I felt. We must have spent around a half hour wandering quietly alone, together, before we left in order to return to the festivities in town. But I’ll never forget the experience. It was something really, really special. I took some video footage too, but I’m not sure yet whether I want to use it. We’ll see! Someday, I’ll set up a tripod and get a shot of me walking like this. But for now, have Joanne instead. ???? <3

(412 geeks have read this)




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Apple Preparing Retail Employees to Return to Work With Tips From South Korea Reopening

Apple in mid-April reopened Apple Garosugil, its lone store in South Korea, located in the Seoul's Gangnam District.


Apple's South Korea reopening has served as a test ground for further store reopenings, and Apple created an instructional video on reopening practices that's now being shared with other retail employees around the world as they prepare to reopen stores. We're not able to share the video, but it provides a good overview of the measures Apple is putting in place to safely operate retail locations.

Retail employees are following a strict set of guidelines that very heavily emphasize social distancing of two meters (or six feet in the United States). Apple is taking the following measures:


  • Prior to when work starts, all employees undergo a health screening complete with a temperature check, with the results logged in a daily spreadsheet.

  • Daily briefings are done in the mornings in the Forum area at Apple Stores, with employees making sure to sit at least two meters apart.

  • Prior to being allowed in the store, customers are also given a temperature check.

  • All ‌Apple Stores‌ are providing hand sanitizer, which customers are encouraged to use.

  • Stores are limiting the number of people inside, forming lines with customers waiting at least two meters apart.

  • Products purchased by customers or returned after repair are delivered from the back in a relay system, being handed off from employee to employee to allow each person to stay in a separated zone without back and forth.

  • Product specialists and Genius Bar staff are positioning themselves across tables away from customers in order to maintain distance.

  • In the forum area, employees sit one cube away from customers they're interacting with.

  • Employees are encouraged to communicate with one another through the Talk app to cut down on unnecessary movement within the store.

  • Half of the workstations in the back are empty, with employees working at alternating workstations to keep more distance between them.

  • Tables have been rearranged to put products on corners to prevent customers from being near one another.

  • Products on tables have been reduced.

  • Communal tables and couches have been removed from employee break rooms and have been replaced with individual chairs evenly spaced about the room.

  • Operating hours are reduced.

  • Employees are all wearing face masks.


After opening its South Korea store on April 16, Apple has reopened its sole store in Vienna, Austria, and 21 stores located in Australia. Stores in Germany will begin reopening on May 11, and all of the newly opened locations are following many of the same guidelines listed above to keep both customers and employees safe.

There's no word yet on when Apple retail stores in the United States will start to reopen, but Apple CEO Tim Cook last week said that stores in North America will begin reopening starting in the month of May.

Apple plans to evaluate data and make reopening decisions on a city by city, county by county basis, following local guidelines and recommendations before opening up a store.
Related Roundup: Apple Stores

This article, "Apple Preparing Retail Employees to Return to Work With Tips From South Korea Reopening" first appeared on MacRumors.com

Discuss this article in our forums




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Dubai detail #1

This isn't quite abstract enough to be unrecognisable, but I like that it's not as immediately obvious as some of my other shots of Dubai.

captured
camera
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7.18am 9/4/16
Fujifilm X-Pro 2
XF 50-140mm f/2.8 R LM OIS WR
180mm
f/5.6
1/80
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+0.7
average
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Photoshop CC (2015.5)
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minor transformation




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Барабанщик METALLICA хвалит Данию за действия против COVID-19

Барабанщик METALLICA Lars Ulrich считает, что его родная страна отлично справляется с мировой пандемией COVID-19.

Дания недавно начала медленно снимать ограничения для сдерживания распространения нового коронавируса. Вновь открылись школы для детей до 11 лет, а также малые предприятия, такие как парикмахерские и тату-салоны. Этот шаг был предпринят спустя чуть более месяца после того, как в Копенгагене были закрыты детские сады, начальные и средние школы, а также кафе, рестораны, бары, тренажёрные залы и парикмахерские. Кроме того, Дания расширила тестирование на коронавирус, включив в него людей со слабыми симптомами. Ранее тестировались только те, у кого симптомы были умеренными или тяжёлыми. Другие ограничения остаются в силе по крайней мере до 10 мая. Границы закрыты, а собрания ограничены 10 людьми.

Ulrich, родившийся в Дании и живший там до 16 лет, а затем переехавший в Лос-Анджелес, обсуждал пандемию коронавируса 28 апреля во разговора с Marc'ом Benioff'ом:

«Дания была одним из первых государств в мире, которое действительно пошло на полное закрытие страны, и там зарегистрировали самые низкие показатели заболеваемости во всей Западной Европе. Всего полторы недели назад они начали открывать детские сады и школы. И пока всё идёт хорошо. Но пока ещё рано говорить о полном успехе.

Я думаю, что мы все должны понимать, где бы мы ни были, по мере того, как мир снова открывается, это не произойдёт за один-два дня, как он был закрыт. Так что это будет очень постепенно. Как мы видим, даже в США есть места, которые начинают открываться, — есть они и в Европе, в Азии и так далее. У каждой страны будет свой набор средств и свои способы возвращения к новой жизни. Но Дания, за которой я ежедневно слежу, ведь я читаю датские газеты и общаюсь с моими друзьями в Дании, уже начала этот процесс. И я думаю, что они показывают весьма впечатляющий старт. Цифры, статистика и всё то, что не претерпело радикальных изменений, на самом деле, показатели продолжают снижаться. Как вы знаете, тут совсем не так, как было в некоторых азиатских странах, когда было дано небольшое послабление, и цифры вновь поползли вверх. Но в Дании пока это выглядит многообещающе.

Когда я думаю о Дании, я думаю только о слове "мы". В Дании всё всегда "мы" и "нас", и куда меньше про "я" и "меня". И поэтому, когда я думаю о том, что Дания пережила этот кризис, я очень горжусь тем, что называю себя датчанином. И я думаю, что прогресс, который там достигается, безусловно, воодушевляет и вдохновляет всех нас».

Когда ведущий спросил у Lars'a, не захочет ли он вернуться в Данию, если коронавирусный кризис в США усугубится, тот ответил, что у него всё ещё есть датский паспорт, и пошутил, что он спит, положив его под подушку:

«Мой датский паспорт находится рядом, если он вдруг понадобится!» #Metallica #ModernRock #Modern_Rock #AvantgardeRock #Avantgarde_Rock #HeavyMetal #Heavy_Metal #SymphonicMetal #Symphonic_Metal #ThrashMetal #Thrash_Metal




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Вокалист METALLICA о коллекции машин

В новом пятиминутном ролике вокалист METALLICA James Hetfield рассказывает о своей коллекции кастом-каров, часть которой он пожертвовал Petersen Automotive Museum в Лос-Анджелесе.. #Metallica #ModernRock #Modern_Rock #AvantgardeRock #Avantgarde_Rock #HeavyMetal #Heavy_Metal #SymphonicMetal #Symphonic_Metal #ThrashMetal #Thrash_Metal




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Барабанщик METALLICA: «RAGE AGAINST THE MACHINE всё более и более актуальны»

В рамках интервью для Rolling Stone барабанщик METALLICA Lars Ulrich ответил на вопрос о том, какая музыка его зацепила за последнее время:

«Я бы назвал Fiona Apple — её пластинка ["Fetch the Bolt Cutters"] просто сногсшибательна. В тот день, когда альбом только вышел, я его слушал часа три-четыре подряд и читал тексты. Честно говоря, я был поражён тем, насколько это необычно и гениально, потому что это так нестандартно. Каждые несколько лет выходит пластинка с другим звучанием. Я думаю, что последние ARCTIC MONKEYS, выпущенные года два назад ["Tranquility Base Hotel & Casino"], также имели схожий эффект, когда ты получаешь совсем не то, что ожидаешь, потом слушаешь это и просто говоришь: "Вау, это всё ещё возможно — сделать что-то музыкальное и не так, как у всех, ты ощущаешь уникальность, свежесть и неожиданность". Так что я бы сказал, что альбом Fiona Apple определённо из этой категории. Мне также нравится альбом Ed'a O'Brien'а. И его выступление на "Kimmel" — мы смотрели его достаточно часто.

В остальном, я думаю, вы заметили, что я больше обращаюсь ко многим своим старым друзьям [в музыкальном плане]. Пожалуй, музыка, которую я слушал больше всего за последние два-три месяца, — это RAGE AGAINST THE MACHINE. Неужели я единственный, кто думает, что их музыка с каждым днём становится всё более и более актуальной? Она всё больше и больше ассоциируется с тем, что происходит в мире. Просто такое ощущение, что все четыре этих альбома были записаны на прошлой неделе. И когда я делаю свои жалкие слабенькие упражнения, надеваю наушники и начинаю заниматься, я выдаю что-то типа: "Охренеть", когда просто слышу что-то в "Calm Like A Bomb", "Sleep Now In The Fire" или "Bombtrack", и думаю: "Не, ну правда, что ли? Какого хрена? Откуда это вообще взялось?" Так что RAGE AGAINST THE MACHINE никогда не подведут!»

Ulrich также рассказал, что слушают члены его семьи:

«В доме довольно часто можно услышать Radiohead. Radiohead начали делать что-то вроде того, что делает Metallica, — они транслируют концерты, так что у нас дом фанатов Radiohead».

На вопрос о том, чем он заполняет своё время в период самоизоляции, Lars ответил:

«Я пытаюсь оставаться здоровым и здравомыслящим и быть как можно более продуктивным. Я пытаюсь быть более физически активным, чем несколько месяцев назад, занимаясь тренировками и играя, вместо того, чтобы валяться на диване. Это помогает чувствовать себя лучше в психологическом плане». #Metallica #ModernRock #Modern_Rock #AvantgardeRock #Avantgarde_Rock #HeavyMetal #Heavy_Metal #SymphonicMetal #Symphonic_Metal #ThrashMetal #Thrash_Metal




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Zdarsky, Fabok, & more ask you to “Be Our Heroes” for Canadian retailers

A fundraising initiative spearheaded by Canadian comic retailers and creators aims to auction off items in order to support their struggling industry.

The post Zdarsky, Fabok, & more ask you to “Be Our Heroes” for Canadian retailers appeared first on The Beat.






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Sunshine Pad Thai (Vegetarian)

The pad thai recipe you're looking for! Try this simple trick to make a turmeric noodle version.

Continue reading Sunshine Pad Thai (Vegetarian) on 101 Cookbooks




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IBM and SAP to Offer New Co-Created Industry Solution for Retail and Consumer Packaged Goods Industries

IBM and SAP SE have teamed up to provide a co-innovated solution for the retail and consumer packaged goods industries to help both increase profitability and improve the consumer experience.




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IBM Services and Retail Analytics to Support Walgreens Field Service Nationwide

IBM today announced a new agreement with Walgreens, one of the country’s largest drugstore chains, to deploy IBM retail analytics at more than 8,100 locations nationwide to help improve the efficiency of field service support for these locations.



  • Services and solutions

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Reta IBM a Creativos en Noche de Desarrolladores por Segundo Año Consecutivo

Alrededor de 60 mentes creativas del emprendimiento y el desarrollo se dieron cita en el DeveloperConnect@Night, en un evento hecho por desarrolladores y para desarrolladores por parte de IBM México en el Plaza Condesa.




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MineHub Technologies colabora con IBM para presentar una solución global de cadena de suministro de minería y metales utilizando blockchain

MineHub Technologies e IBM anunciaron hoy una colaboración para utilizar la tecnología blockchain con el objetivo de mejorar la eficiencia operativa, logística, financiamiento y reducir los costos en la cadena de suministro de concentrados minerales de alto valor, desde la mina hasta el comprador final.




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Dona IBM Servicios de Consultoría a Organizaciones Queretanas para Proyectos de Impacto Social

IBM, Peace Corps y cuatro instituciones locales dieron inicio el día de hoy al programa de consultoría Corporate Service Corps (CSC), en su edición Cd. de Querétaro; con la finalidad de apoyar el desarrollo de proyectos de alto impacto en esta localidad. IBM y Peace Corps (PC) trabajarán en conjunto con la Secretaría de Desarrollo Social del Estado de Querétaro, el Instituto Queretano de las Mujeres, el Municipio de Querétaro - Delegación Santa Rosa Jáuregui, y la Universidad Politécnica de Santa Rosa Jáuregui (UPSRJ).




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IBM study finds majority of Australian shoppers “apathetic” towards retailers, hungry for multi-channel innovation

An IBM (NYSE: IBM) study of 26,000 consumers from 14 countries -- including almost 2,000 Australians.-- found that over 60% of Australian consumers identify themselves as “apathetic” in their choice of primary retailer – almost double those who see themselves as advocates of a particular retailer. As such Australian retailers have a significant opportunity to capture shopper loyalty, but they need to capitalise on existing investments in multi-channel and accelerate customer engagement across all channels, including mobile devices and social media platforms in order to win in this globally competitive sector.



  • Services and solutions

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IBM Customer Experience Index Shows Aussie Retailers Missing Omni-Channel Opportunity

IBM, (NYSE: IBM) today announced the findings of its 2016 Global Customer Experience Index (CEI) Study, which showed that Australia is above the global average when it comes to providing a good shopping experience for consumers, with a CEI rating of 43 percent compared with 40 percent globally. The results provided a snapshot of the Australian retail sector, revealing that some businesses are still struggling to provide a seamless cross-channel experience, personalisation and convenience for customers.




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Živnostníky podpoří program Pětadvacítka, odpuštění záloh či odklad daní

Preventivní opatření proti nákaze covid-19 zasáhla jak firmy všech velikostí, tak živnostníky. Jenže právě osoby samostatně výdělečně činné patří podle vlády ke skupinám, které krize vyvolaná pandemií nejvíce ohrozí. Zejména pak ty, kteří mají živnost jako hlavní zdroj příjmů a nemají ji jako přivýdělek k zaměstnání. Jak je stát podpoří?



  • Finance - Finanční rádce

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Beta readers?

ETA: You guys are amazing. I was really not expecting to get so many volunteers! I have more than enough people for now. I'm happy to add any additional names to the list for future opportunities. I can't add any more volunteers for this course, otherwise it would end up being all my friends which isn't great for diversity.


My awesome job involves creating free online courses about genomics. The first course I've been fully in charge of is about to go live, and it needs some final quality checks. It's quite exciting IMO: it's about using genomics to identify and avoid antibiotic resistance.

We need people who can put in a couple of hours in the next week, and just play around with the course and see if there are any obvious problems, whether that's technical issues like display problems for your particular hardware and software, or conceptual problems like confusing instructions or something that doesn't make sense. We are definitely not expecting any one individual to go through the whole course in detail, and we're not looking for copy editing or proofreading. I mean, if you have the sort of brain that can't help spotting typos, we don't mind reports of those, but we're mainly looking for something more general than that.

We want people from all backgrounds, so a mix of people who know something about microbiology and genomics, and people who have no idea. I will say that the course is fairly technical, though, so you probably don't want to volunteer if sciencey stuff is hateful or scary to you. We are especially happy to have beta readers who aren't completely fluent in English to be more representative of our target audience.

Other than doing some good for the world, what you get out of it is a £25 Amazon voucher. So in order to get paid you need to be in a position to receive and spend an Amazon voucher. We might possibly be able to acquire vouchers for other countries' versions of Amazon, or else I can informally arrange to swap to something more locally useful. But it's not employment, it's a volunteer thing with a small token of appreciation.

Feel free to ask questions in the comments, but if you actually want to sign up you need to interact with my work persona, so I'll ask you to PM me about arranging that. You're also welcome to pass the request on to anyone else who might be interested. The number of available slots is somewhat flexible, probably in the range of 3-5.

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A Metaphor for our Television Addiction

From the submitter:

So I get up today and the kids are up before me watching TV. That's fine, it Sunday, got to sleep in, figured I go check my email and puts around online for a few. Later I go into the living room, to turn the TV so I can start watching Game highlights before the Super Bowl, but can not find the remote. I mean I searched everywhere. The usual places... In the couch cushions, under the couch, behind the couch and behind the TV.... nowhere to be found.




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F&S betalen zich nog steeds blauw aan de pomp (NRC, wo, 29-04-20)




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Impact of antiretroviral therapy on liver disease progression and mortality in patients co-infected with HIV and hepatitis C: systematic review and meta-analysis

Systematic review produced by the EPPI-Centre in 2015.This systematic review aimed to evaluate the effect of HAART and ARV monotherapy on liver disease progression and liver-related mortality in individuals co-infected with HIV and hepatitis C, including in patients with haemophilia.





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Where do baby magnetars come from? Mysterious 'fast radio bursts' may provide clues.

Magnetars — highly magnetized, rapidly rotating super-dense stars — are among the most enigmatic creatures to inhabit the cosmos and their origins are shrouded in mystery.