The invention relates to the quantitative measurement of steroidal compounds by mass spectrometry. In a particular aspect, the invention relates to methods for quantitative measurement of steroidal compounds from multiple samples by mass spectrometry.

A process for the purification of organometallic compounds or heteroatomic organic compounds from oxygen, water and from the compounds deriving from the reaction of water and oxygen with the organometallic or heteroatomic compounds whose purification is sought, comprising the operation of contacting the organometallic or heteroatomic compound to be purified in the liquid state or in form of vapor, pure or in a carrier gas, with a hydrogenated getter alloy, and optionally also with one or more gas sorber materials selected among palladium on porous supports and a mixture of iron and manganese supported on zeolites.

Method and apparatus for handling aerogenerator blades that provide a versatile means for handling aerogenerator blades without an unbalanced distribution of the loads in the blade. The method comprises positioning an upper mounting part (103) over the blade after the upper mold has been retracted; lifting the blade with the upper mounting part from the under mold using a lifting means; positioning the blade over an under mounting part (104) which is fixedly attached to an inferior movable support (102); attaching the upper mounting part to the under mounting part, wherein the upper and under mounting parts together have the inner surface substantially corresponding to the shape of the blade outer profile section. The invention further comprises an apparatus for handling aerogenerator blades.

Methods and circuits related to a driving circuit with zero current shutdown are disclosed. In one embodiment, a driving circuit with zero current shutdown can include: a linear regulating circuit that receives an input voltage source, and outputs an output voltage; a start-up circuit having a threshold voltage, the start-up circuit receiving an external enable signal; a first power switch receiving both the output voltage of the linear regulating circuit and the external enable signal, and that generates an internal enable signal, the internal enable signal being configured to drive a logic circuit; when the external enable signal is lower than a threshold voltage, the driving circuit is not effective; when the external enable signal is higher than the threshold voltage, the start-up circuit outputs a first current; and where the output voltage at the first output terminal is generated by the linear regulating circuit based on the first current.

A method of configuring a programmable integrated circuit device with a user logic design includes analyzing the user logic design to identify unidirectional logic paths within the user logic design and cyclic logic paths within the user logic design, assigning the cyclic logic paths to logic in a first portion of the programmable integrated circuit device that operates at a first data rate, assigning the unidirectional logic paths to logic in a second portion of the programmable integrated circuit device that operates at a second data rate lower than the first data rate, and pipelining the unidirectional data paths in the second portion of the programmable integrated circuit device to compensate for the lower second data rate. A programmable integrated circuit device adapted to carry out such method may have logic regions operating at different rates, including logic regions with programmably selectable data rates.

A seating unit that includes a linkage mechanism adapted to move the seating unit between seat-lift, closed, extended, reclined, and seat-lift positions is provided. The linkage mechanism includes a seat-mounting plate mounted to a footrest assembly, a base plate fixedly mounted to a lift assembly, a back-mounting link rotatably coupled to the seat-mounting plate, a seat-adjustment assembly with a bellcrank, and a linear actuator for automating adjustment of the linkage mechanism. In operation, a stroke in a first phase of the linear actuator generates a force on the bellcrank that translates the seat-mounting plate rearward in a consistent angle of inclination and rotates the back-mounting link from a reclined to an upright orientation. A stroke in a second phase acts to collapse the footrest assembly. A stroke in a third phase causes the lift assembly to raise and tilt the seating unit, thereby accommodating egress and ingress of an occupant.

Disclosed are metal-containing precursors having the formula Compound (I) wherein: —M is a metal selected from Ni, Co, Mn, Pd; and —each of R-1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 are independently selected from H; a C1-C4 linear, branched, or cyclic alkyl group; a C1-C4 linear, branched, or cyclic alkylsilyl group (mono, bis, or tris alkyl); a C1-C4 linear, branched, or cyclic alkylamino group; or a C1-C4 linear, branched, or cyclic fluoroalkyl group. Also disclosed are methods of synthesizing and using the disclosed metal-containing precursors to deposit metal-containing films on a substrate via a vapor deposition process.

An electrical machine includes a stator having a main armature winding, an exciter field winding, and a transformer primary winding. A rotor is operatively connected to rotate relative to the stator, wherein the rotor includes an exciter armature winding operatively connected to the exciter armature winding for field excitation therebetween, a main field winding operatively connected to the main armature winding for field excitation therebetween, and a transformer secondary winding operatively connected to the transformer primary winding to form a rotating transformer. A generator control unit is operatively connected to the main armature winding, exciter field winding, and transformer primary winding to control the main armature and exciter field windings based on excitation in the primary winding received from the transformer secondary winding.

This technology is a method and apparatus for the semi-continuous measurement of the concentration of constituents of airborne particles which couples a laminar flow, water condensation particle collector to a microfluidic device for assay of particle chemical composition by electrophoresis. The technology has been used for the assay of sulfates, nitrates, chlorides, and organic acids contained in fine and submicrometer atmospheric particles. For these compounds the apparatus and method described is capable of one-minute time resolution at concentrations at the level of micrograms of analyte species per cubic meter of air. Extension to other analytes is possible.

A sensor system, device, and methods for determining the concentration of an analyte in a sample is described. Input signals including multiple duty cycles of sequential excitation pulses and relaxations are input to the sample. One or more signals output from the sample within 300 ms of the input of an excitation pulse may be correlated with the analyte concentration of the sample to improve the accuracy and/or precision of the analysis. Determining the analyte concentration of the sample from these rapidly measured output values may reduce analysis errors arising from the hematocrit effect, mediator background, and other error sources.

An electronic device includes a silicon carbide layer including an n-type drift region therein, a contact forming a junction, such as a Schottky junction, with the drift region, and a p-type junction barrier region on the silicon carbide layer. The p-type junction barrier region includes a p-type polysilicon region forming a P-N heterojunction with the drift region, and the p-type junction barrier region is electrically connected to the contact. Related methods are also disclosed.

The present teachings relate to new semiconducting polymers. The polymers disclosed herein can exhibit high carrier mobility and/or efficient light absorption/emission characteristics, and can possess certain processing advantages such as solution-processability and/or good stability at ambient conditions.

A circuit interrupter includes, a first contact and a second contact, the second contact being moveable relative to the first contact, a drive assembly structured to move the second contact relative to the first contact, and an erosion monitoring device including a linear transducer coupled to a portion of the drive assembly. The liner transducer is structured to generate an output signal representative of an amount of linear displacement of the portion of the drive assembly, wherein the erosion monitoring device is structured to monitor a degree of erosion of at least one of the first contact and the second contact based on the output signal.

The present invention provides an assembly for the preparation of a medical device having a porous coating comprising hydrogen peroxide. Particularly interesting medical devices are catheters (such as urinary catheters), endoscopes, laryngoscopes, tubes for feeding, tubes for drainage, guide wires, condoms, urisheaths, barrier coatings e.g. for gloves, stents and other implants, extra corporeal blood conduits, membranes e.g. for dialysis, blood filters, devices for circulatory assistance, dressings for wound care, and ostomy bags. The coating is in particular a hydrophilic coating formed from cross-linked polyvinylpyrrolidone. In one embodiment, the assembly holds a dry catheter element in one compartment of a package and an aqueous hydrogen peroxide solution in another compartment. The solution may also comprise stabilizers, e.g. chelators, and osmolality increasing agents. The catheter for insertion in the urethra is useful for the treatment, alleviation or prophylaxis of microbial infections such as urinary tract infections (UTI).

A fascia support structure and aerodynamic shutter assembly for a vehicle includes a fascia support structure, comprising: a top portion comprising a substantially U-shaped body comprising a top fascia support member, a first side fascia support member and a second side fascia support member, the first side fascia support member having a first side baffle, the second side fascia support member having a second side baffle; and a bottom portion comprising a bottom baffle, the bottom portion attached to the first and second side fascia support members, the top portion and the bottom portion comprising a fascia support structure opening, at least one of the first side baffle, second side baffle or bottom baffle having a seal member disposed on a leading edge. The assembly also includes an aerodynamic shutter system comprising a shutter frame having a shutter frame opening and a plurality of rotatable shutters disposed therein.

A fascia support structure and aerodynamic shutter assembly for a vehicle includes a fascia support structure, comprising: a top portion comprising a substantially U-shaped body comprising a top fascia support member, a first side fascia support member and a second side fascia support member, the first side fascia support member having a first side baffle, the second side fascia support member having a second side baffle; and a bottom portion comprising a bottom baffle, the bottom portion attached to the first and second side fascia support members, the top portion and the bottom portion comprising a fascia support structure opening, at least one of the first side baffle, second side baffle or bottom baffle having a seal member disposed on a leading edge. The assembly also includes an aerodynamic shutter system comprising a shutter frame having a shutter frame opening and a plurality of rotatable shutters disposed therein.

The present invention describes a method of optimizing CO2 concentration to increase the specific growth rate of Anammox bacteria and methanogens in wastewater and sludge treatment, as well as novel systems and methods of treating wastewater and sludge. The specific growth rate or doubling time of the Anammox bacteria and methanogens were determined to be sensitive to dissolved CO2 concentration. Optimizing dissolved CO2 concentration increases the specific growth rate of the Anammox bacteria, which may be used as an alternative biological nitrogen removal process for the treatment of domestic wastewater. In the method and system of treating sludge, the CO2 stripper returns biogas with low CO2 concentration to the headspace of an anaerobic digester in order to lower the headspace CO2 concentration and therefore, the soluble CO2 concentration. The lower soluble CO2 concentration increases the specific growth rate of the methanogens for a more efficient anaerobic digestion process.

Individually operable ailerons pivotable to extend a forward end below a bottom wing surface and a rearward end above a top wing surface. The extended aileron forward end increases drag and subsumes the rudder function in the turn, while the aileron rear end produces drag and airflow redirection to reduce lift on the wing. The advantage of the safety ailerons is that habitual or instinctive pilot inputs to the yoke will recover from a dropped-wing stall at low speed and altitude, while conventional ailerons require counter-intuitive pilot actions to avoid crashing in such conditions.

An arrangement of aerodynamic auxiliary surfaces is configured for being arranged on the underside of an aircraft and furthermore includes a longitudinal axis and at least one aerodynamic auxiliary surface, wherein the aerodynamic auxiliary surface is laterally offset referred to the longitudinal axis, and wherein the aerodynamic auxiliary surface is configured for generating vortices when it is subjected to an oncoming air flow. This makes it possible to compensate vortices caused by the shape of the aircraft such that the directional stability of the aircraft can be improved and the aerodynamic drag may be reduced.

A projectile control system includes a plurality of fins, a drive mechanism coupled to each of the plurality of fins to enable the plurality of fins to be independently retracted or deployed, and a control mechanism in communication with the drive mechanisms to independently control the deployment or retraction of the plurality of fins. A projectile having the projectile control system and a method of operating a projectile are also described herein.

The invention describes a regulating device that adapts to the aerodynamic profile of a mold bed made of composite material offsetting the geometrical deviations occurring in the mold bed. The device comprises some stiffening ribs (20) supported on a surface of the bed (10) of the mold and is equipped with actuators (21) that modify the curvature of the bed (10) of the mold.

A mounting member fitted and mounted on an open head portion of an aerosol container 11 having an inner diameter of 1 inch is formed with two valve housing mounting portions. The mounting member is fitted and mounted with the middle portion of this mounting member being located at a bead 12 of the opening head portion of the aerosol container 11 in such a manner that the upper portions of aerosol valves project upwardly from the opening head portion. A cover 19 covering the outside of the mounting member is crimped to the outside of the bead 12 in a manner to hold down a stem gasket and two aerosol valves are provided in the inch can 11. A reinforcing cover member which holds down the stem gasket and prevents deformation of the cover is provided between the mounting member and the cover 19 to thereby accurately prevent deformation due to internal pressure applied to a top ceiling of the cover and leakage from the stem gasket. An aerosol device for dispensing plural kinds of liquids in which two aerosol valves for dispensing and injecting contents liquids are disposed in a standard aerosol container with a bead having an inner diameter of 1 inch can thereby be provided.

An aerosol device is provided with a set of two aerosol valves in an inch bead portion of an aerosol container, and different contents are separately packed in the aerosol container without being mixed. The different contents are separately introduced into the set of two aerosol valves, and the stem insertion portions of housings of the set of two aerosol valves project above the inch bead portion. The lower end of a fitting member whose inner peripheral shape corresponds to the outer peripheral shape of the set of two housings is fitted and fixed to the inner periphery of the inch bead portion. The outer periphery of the fitting member is covered with a cover, and the lower end of the cover is fixed to the outer periphery of the inch bead portion.

A sealing system for a pump having a plunger includes a housing having an internal chamber adapted to receive a portion of the plunger. Primary and secondary seals are located within the internal chamber and adapted to sealingly engage the plunger. The primary seal communicates with the fluid being pumped. A barrier fluid chamber contains a barrier fluid in contact with the primary seal and the secondary seal. A pressure referencing device has an inlet port in communication with the pumped fluid and an outlet port providing fluid at a pressure magnitude equal to a peak pressure of the pumped fluid. A pressurizing device is in communication with the fluid at the peak pressure and the barrier fluid to maintain the barrier fluid pressure at a magnitude greater than the peak pressure of the pumped fluid such that the pumped fluid is restricted from leaking past the primary seal.

An aero-engine low pressure pump is provided for supplying fuel at a raised pressure to a high pressure pump. The low pressure pump has a pumping mechanism which raises the pressure of fuel flowing though the mechanism. The low pressure pump further has electrical motor which drives the pumping mechanism. The low pressure pump further has a variable frequency motor drive which supplies electrical power to the electrical motor. The variable frequency motor drive measures the electrical power supplied to the electrical motor. The low pressure pump further has a control unit which compares the measured electrical power to a reference power, and, when the measured electrical power is less than the reference power by a predetermined amount, controls the motor drive to increase the power supplied to the electrical motor thereby increasing the pressure rise produced by the pumping mechanism.

The disclosure generally describes methods, software, and systems, including a method for updating an application. At least one application instance of an application is managed. Each application instance is associated with a plurality of executing work processes connected with a first database schema. A bridge database schema is generated that is related to the first database schema. The bridge database schema represents a copy of the first database schema and is generated in response to initiation of an update to the application. In response to determining that the generation of the bridge database schema is complete, for each of the plurality of work processes, a commit work action performed by the particular work process is determined. In response to determining performance of the commit work action, the particular work process is connected to the bridge database schema.

Disclosed is spin-stabilized ammunition for use in grooved or smooth bore handheld firearms with calibers up to 60 mm. The projectile of the ammunition features a body in the shape of a truncated cone at the top of a cylinder with proportions of the cone length to the cylinder length varying between from one-to-six to one-to-three depending on the expected initial speed of the projectile after the ammunition has been discharged. A central longitudinal barrel extends through the projectile with a proportion of the entrance diameter and exit diameter of 1.38-to-one for expected discharge speeds near sound velocity or of 1.22-to-one for expected discharge of hypersonic velocities. Finally, nozzles within the projectile create a spinning motion around the projectile's axis, the nozzles being located between cavities for propellant charges.

Provided is bearing steel excellent in workability after spheroidizing-annealing and in hydrogen fatigue resistance property after quenching and tempering. The bearing steel has a chemical composition containing, by mass %: 0.85% to 1.10% C; 0.30% to 0.80% Si; 0.90% to 2.00% Mn; 0.025% or less P; 0.02% or less S; 0.05% or less Al; 1.8% to 2.5% Cr; 0.15% to 0.4% Mo; 0.0080% or less N; and 0.0020% or less O, which further contains more than 0.0015% to 0.0050% or less Sb, with the balance being Fe and incidental impurities, to thereby effectively suppress the generation of WEA even in environment where hydrogen penetrates into the steel, so as to improve the roiling contact fatigue life and also the workability such as cuttability and forgeability of the material.

Non-naturally occurring peptides are provided that act as a Src SH2 domain antagonist of cardiotonic steroids. Pharmaceutical compositions comprising the peptides are also provided along with vectors encoding the peptides. Methods of treating a Src-associated disease and reducing Src activity in a cell are further provided and include administering or contacting a cell with an effective amount of the peptide.

An excavator includes a mobile chassis with a first bucket drum and a second bucket drum coupled thereto. The first bucket drum and second bucket drum are coupled to the chassis for positioning thereof on the surface at opposing ends of the chassis. Each first scoop on the first bucket drum is a mirror image of one second scoop on the second bucket drum when (i) the first bucket drum and second bucket drum are on the surface adjacent opposing ends of the chassis, and (ii) the first bucket drum is rotated in one direction and the second bucket drum is simultaneously rotated in an opposing direction.

Devices, cartridges, and method are described herein for emulating smoking wherein a device generates an aerosol for inhalation by a subject by heating a viscous material that can have a tactile response in the mouth or respiratory tract, while reducing Hoffman analytes and mutagenic compounds delivered to the user as compared to a common tobacco cigarette.

A semiconductor memory device may include: a memory bank comprising a plurality of word lines; a smart command generation unit suitable for generating a smart refresh command, which is enabled at a random cycle, in response to an active command; and a refresh operation control unit suitable for performing a refresh operation to at least one of adjacent word lines of a target word line among the plurality of word lines in response to the smart refresh command.

A driven damper assembly, comprises a first main-damper cover plate comprising an inclined portion. The inclined portion comprises a notch. A first plane passes through the first pre-damper cover plate. A second plane passes through the first main-damper cover plate and is parallel to the first plane. The notch comprises a first wall and a second wall. The first wall is not parallel to the second wall. The inclined portion extends away from the second plane at an angle greater than zero degrees away from the second plane and less than ninety degrees away from the second plane. The first pre-damper cover plate comprises a tab with a first portion extending outwardly at an angle greater than zero degrees away from the first plane and less than ninety degrees away from the first plane, wherein the tab engages the notch at the first wall and the second wall.

A composition for forming an electroactive coating includes an acid as a polymerization catalyst, at least one functional component, and at least one compound of formula (1) as a monomer: wherein X is selected from S, O, Se, Te, PR2 and NR2, Y is hydrogen (H) or a precursor of a good leaving group Y− whose conjugate acid (HY) has a pKa of less than 45, Z is hydrogen (H), silyl, or a good leaving group whose conjugate acid (HY) has a pKa of less than 45, b is 0, 1 or 2, each R1 is a substituent, and the at least one compound of formula (1) includes at least one compound of formula (1) with Z=H and Y≠H.

A method is provided for making smooth crystalline semiconductor thin-films and hole and electron transport films for solar cells and other electronic devices. Such semiconductor films have an average roughness of 3.4 nm thus allowing for effective deposition of additional semiconductor film layers such as perovskites for tandem solar cell structures which require extremely smooth surfaces for high quality device fabrication.

Solid carboniferous fuels contain varying quantities of moisture, mercury, chlorine, nitrogen, sulfur, heavy metals and other materials that attain vapor pressure at elevated temperatures. The cost effective removal of these degrading and sometimes hazardous materials is important to the further use of the fuel for combustion as a solid, liquid, or gas. The solid fuel is cut, shredded, ground or sieved to appropriate size, and heated in a chamber that can exclude oxygen and air thus preventing ignition. The unwanted materials are driven in the gaseous state and extracted for disposal. The solid fuel cleaned of pollutants exits the chamber and is cooled below ignition temperature prior to contact with oxygen. The solid fuel thus purified is more appropriate for combustion, liquefaction or gasification due to the reduced costs in use as a fuel or in the post combustion clean up.

A system for growing plants without soil uses removable V-shaped baskets to support plants in a tiered, self-contained unit. Nutrient enriched water is sprayed on the plant roots. The roots are held by perforations in the elongated V-shaped basket and a plant blanket. The unit is multilevel and can be set over an aquarium. The growing shelf can have a worm bag in order to add natural nutrients. Baskets can be comprised of a pair of identical halves that can be readily mutually coupled. Coupling mechanisms can include those that snap together and those providing for a pivoting coupling.

An aerosol delivery system has a nebulizer and a humidifier providing a gas flow to the nebulizer. A controller varies humidity level of the gas flow to the nebulizer so that if the nebulizer is not operating it has about 100% humidity and it is operating the value is less to allow for the humidification effect of the nebulizer. The control may be achieved by dynamically varying proportions of flow through a dry branch and a humidification branch.

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An amino-containing silica particle is provided. The amino-containing silica particle is obtained by hydrolysis-condensation reaction of an alkoxy silane represented by formula (I), an alkoxy silane represented by formula (II) and a catalyst: Si(OR1)4 formula (I) (NH2—Y)m—Si(OR2)4-m formula (II) wherein in formula (I), R1 is a C1-C10 alkyl group, and in formula (II), Y is a C1-C10 alkyl group or a C2-C10 alkenyl group, R2 is a C1-C10 alkyl group, and m is an integer of 1 to 3.

In one example embodiment, a system for treating a tissue site is disclosed comprising a dressing adapted to contact the tissue site and provide a fluid seal between a therapeutic environment and a local external environment, and a solution source fluidly coupled to the dressing and adapted to deliver an antimicrobial solution comprising a peroxy α-keto carboxylic acid, such as peroxy pyruvic acid, to the tissue interface. The system may further comprise a negative-pressure source fluidly coupled to the dressing and adapted to provide negative pressure to the therapeutic environment after delivery of the antimicrobial fluid to the therapeutic environment. In another example embodiment, a method for treating a tissue site is disclosed comprising positioning a tissue interface to contact the tissue site, covering the tissue interface and the tissue site with a drape to provide a fluid seal between the therapeutic environment and the local external environment, and delivering an antimicrobial solution comprising peroxy α-keto carboxylic acid to the therapeutic environment before providing negative pressure to the therapeutic environment.

A mass sensor is provided for measuring a particle mass within an aerosol. The duration of a sensing cycle is set such that a pre-set change in mass resulting from particles deposited is caused. In the absence of cleaning, the lifetime of the sensor is dependent on the total mass deposited. As a result, the lifetime is made essentially constant by this approach, because each sensing operation is made to give rise to a constant amount of deposited particle mass. This means the lifetime can be predicted more accurately.

The invention relates to a method for controlling the divergence of a jet of particles in vacuo with an aerodynamic lens, the aerodynamic lens including at least one chamber; a diaphragm, a so-called inlet diaphragm, intended to form an inlet of the aerodynamic lens for a jet of particles, the inlet diaphragm having a given diameter (d1); and another diaphragm, a so-called outlet diaphragm, intended to form an outlet of the aerodynamic lens for this jet of particles; the method including: a step for generating the jet of particles from the inlet to the outlet, in vacuo, of the aerodynamic lens; and a step for adjusting the diameter (ds) of the outlet diaphragm for controlling the divergence of the jet of particles.

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A system and method for detecting a biomarker in exhaled breath condensate nanodroplets comprises noninvasively collecting exhaled breath condensate nanodroplets of a subject, and analyzing said nanodroplets utilizing immuno-quantitative polymerase chain reaction to detect one or more target biomarkers.

The present specification provides a hetero-cyclic compound and an organic light emitting device including the hetero-cyclic compound.

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