ad The Bayesian Update: Variational Formulations and Gradient Flows By projecteuclid.org Published On :: Mon, 13 Jan 2020 04:00 EST Nicolas Garcia Trillos, Daniel Sanz-Alonso. Source: Bayesian Analysis, Volume 15, Number 1, 29--56.Abstract: The Bayesian update can be viewed as a variational problem by characterizing the posterior as the minimizer of a functional. The variational viewpoint is far from new and is at the heart of popular methods for posterior approximation. However, some of its consequences seem largely unexplored. We focus on the following one: defining the posterior as the minimizer of a functional gives a natural path towards the posterior by moving in the direction of steepest descent of the functional. This idea is made precise through the theory of gradient flows, allowing to bring new tools to the study of Bayesian models and algorithms. Since the posterior may be characterized as the minimizer of different functionals, several variational formulations may be considered. We study three of them and their three associated gradient flows. We show that, in all cases, the rate of convergence of the flows to the posterior can be bounded by the geodesic convexity of the functional to be minimized. Each gradient flow naturally suggests a nonlinear diffusion with the posterior as invariant distribution. These diffusions may be discretized to build proposals for Markov chain Monte Carlo (MCMC) algorithms. By construction, the diffusions are guaranteed to satisfy a certain optimality condition, and rates of convergence are given by the convexity of the functionals. We use this observation to propose a criterion for the choice of metric in Riemannian MCMC methods. Full Article
ad A Bayesian Conjugate Gradient Method (with Discussion) By projecteuclid.org Published On :: Mon, 02 Dec 2019 04:00 EST Jon Cockayne, Chris J. Oates, Ilse C.F. Ipsen, Mark Girolami. Source: Bayesian Analysis, Volume 14, Number 3, 937--1012.Abstract: A fundamental task in numerical computation is the solution of large linear systems. The conjugate gradient method is an iterative method which offers rapid convergence to the solution, particularly when an effective preconditioner is employed. However, for more challenging systems a substantial error can be present even after many iterations have been performed. The estimates obtained in this case are of little value unless further information can be provided about, for example, the magnitude of the error. In this paper we propose a novel statistical model for this error, set in a Bayesian framework. Our approach is a strict generalisation of the conjugate gradient method, which is recovered as the posterior mean for a particular choice of prior. The estimates obtained are analysed with Krylov subspace methods and a contraction result for the posterior is presented. The method is then analysed in a simulation study as well as being applied to a challenging problem in medical imaging. Full Article
ad High-Dimensional Confounding Adjustment Using Continuous Spike and Slab Priors By projecteuclid.org Published On :: Tue, 11 Jun 2019 04:00 EDT Joseph Antonelli, Giovanni Parmigiani, Francesca Dominici. Source: Bayesian Analysis, Volume 14, Number 3, 825--848.Abstract: In observational studies, estimation of a causal effect of a treatment on an outcome relies on proper adjustment for confounding. If the number of the potential confounders ( $p$ ) is larger than the number of observations ( $n$ ), then direct control for all potential confounders is infeasible. Existing approaches for dimension reduction and penalization are generally aimed at predicting the outcome, and are less suited for estimation of causal effects. Under standard penalization approaches (e.g. Lasso), if a variable $X_{j}$ is strongly associated with the treatment $T$ but weakly with the outcome $Y$ , the coefficient $eta_{j}$ will be shrunk towards zero thus leading to confounding bias. Under the assumption of a linear model for the outcome and sparsity, we propose continuous spike and slab priors on the regression coefficients $eta_{j}$ corresponding to the potential confounders $X_{j}$ . Specifically, we introduce a prior distribution that does not heavily shrink to zero the coefficients ( $eta_{j}$ s) of the $X_{j}$ s that are strongly associated with $T$ but weakly associated with $Y$ . We compare our proposed approach to several state of the art methods proposed in the literature. Our proposed approach has the following features: 1) it reduces confounding bias in high dimensional settings; 2) it shrinks towards zero coefficients of instrumental variables; and 3) it achieves good coverages even in small sample sizes. We apply our approach to the National Health and Nutrition Examination Survey (NHANES) data to estimate the causal effects of persistent pesticide exposure on triglyceride levels. Full Article
ad Larry Brown’s Work on Admissibility By projecteuclid.org Published On :: Wed, 08 Jan 2020 04:00 EST Iain M. Johnstone. Source: Statistical Science, Volume 34, Number 4, 657--668.Abstract: Many papers in the early part of Brown’s career focused on the admissibility or otherwise of estimators of a vector parameter. He established that inadmissibility of invariant estimators in three and higher dimensions is a general phenomenon, and found deep and beautiful connections between admissibility and other areas of mathematics. This review touches on several of his major contributions, with a focus on his celebrated 1971 paper connecting admissibility, recurrence and elliptic partial differential equations. Full Article
ad Rejoinder: Response to Discussions and a Look Ahead By projecteuclid.org Published On :: Fri, 12 Apr 2019 04:00 EDT Vincent Dorie, Jennifer Hill, Uri Shalit, Marc Scott, Dan Cervone. Source: Statistical Science, Volume 34, Number 1, 94--99.Abstract: Response to discussion of Dorie (2017), in which the authors of that piece express their gratitude to the discussants, rebut some specific criticisms, and argue that the limitations of the 2016 Atlantic Causal Inference Competition represent an exciting opportunity for future competitions in a similar mold. Full Article
ad Tapadh leibh airson nach do smoc sibh / design : Biman Mullick. By search.wellcomelibrary.org Published On :: London (33 Stillness Rd, SE23 1NG) : Cleanair, Campaign for a Smoke-free Environment, [198-?] Full Article
ad Ha gubin wadnahaaga! = Heart burn. / design : Biman Mullick. By search.wellcomelibrary.org Published On :: London : Cleanair (33 Stillness Rd, London, SE23 1NG), [198-?] Full Article
ad Tapadh leibh airson nach do smoc sibh / design: Biman Mullick. By search.wellcomelibrary.org Published On :: London (33 Stillness Road London SE23 1NG) : Cleanair Campaign for a Smoke-free Environment, [198-?] Full Article
ad Smoking is bad for your image / design : Biman Mullick. By search.wellcomelibrary.org Published On :: [London?], [199-?] Full Article
ad Taylor Swift, Hailey Bieber, and Tons of Other Celebs’ Favorite Leggings Are on Sale Ahead of Black Friday By www.health.com Published On :: Wed, 27 Nov 2019 14:16:17 -0500 Here’s where you can snag their Alo Yoga Moto leggings for less. Full Article
ad Forget Black Booties, Amal Clooney and J.Lo Are Wearing This Weather-Resistant Boot Trend Instead By www.health.com Published On :: Tue, 10 Dec 2019 15:31:21 -0500 And it’s on sale at Nordstrom. Full Article
ad Gut Microbes and the Brain: Paradigm Shift in Neuroscience By www.jneurosci.org Published On :: 2014-11-12 Emeran A. MayerNov 12, 2014; 34:15490-15496Symposium Full Article
ad Readiness Potential and Neuronal Determinism: New Insights on Libet Experiment By www.jneurosci.org Published On :: 2018-01-24 Karim FifelJan 24, 2018; 38:784-786Journal Club Full Article
ad Advances in Enteric Neurobiology: The "Brain" in the Gut in Health and Disease By www.jneurosci.org Published On :: 2018-10-31 Subhash KulkarniOct 31, 2018; 38:9346-9354Symposium and Mini-Symposium Full Article
ad Microglia Actively Remodel Adult Hippocampal Neurogenesis through the Phagocytosis Secretome By www.jneurosci.org Published On :: 2020-02-12 Irune Diaz-AparicioFeb 12, 2020; 40:1453-1482Development Plasticity Repair Full Article
ad Synaptic Specificity and Application of Anterograde Transsynaptic AAV for Probing Neural Circuitry By www.jneurosci.org Published On :: 2020-04-15 Brian ZinggApr 15, 2020; 40:3250-3267Systems/Circuits Full Article
ad The Representation of Semantic Information Across Human Cerebral Cortex During Listening Versus Reading Is Invariant to Stimulus Modality By www.jneurosci.org Published On :: 2019-09-25 Fatma DenizSep 25, 2019; 39:7722-7736BehavioralSystemsCognitive Full Article
ad Daily Marijuana Use Is Not Associated with Brain Morphometric Measures in Adolescents or Adults By www.jneurosci.org Published On :: 2015-01-28 Barbara J. WeilandJan 28, 2015; 35:1505-1512Neurobiology of Disease Full Article
ad Grey Matter Volume Differences Associated with Extremely Low Levels of Cannabis Use in Adolescence By www.jneurosci.org Published On :: 2019-03-06 Catherine OrrMar 6, 2019; 39:1817-1827BehavioralSystemsCognitive Full Article
ad Endothelial Adora2a Activation Promotes Blood-Brain Barrier Breakdown and Cognitive Impairment in Mice with Diet-Induced Insulin Resistance By www.jneurosci.org Published On :: 2019-05-22 Masaki YamamotoMay 22, 2019; 39:4179-4192Neurobiology of Disease Full Article
ad Increased Neural Activity in Mesostriatal Regions after Prefrontal Transcranial Direct Current Stimulation and L-DOPA Administration By www.jneurosci.org Published On :: 2019-07-03 Benjamin MeyerJul 3, 2019; 39:5326-5335Systems/Circuits Full Article
ad Three-dimensional structure of dendritic spines and synapses in rat hippocampus (CA1) at postnatal day 15 and adult ages: implications for the maturation of synaptic physiology and long-term potentiation [published erratum appears in J Neurosci 1992 Aug;1 By www.jneurosci.org Published On :: 1992-07-01 KM HarrisJul 1, 1992; 12:2685-2705Articles Full Article
ad Head-direction cells recorded from the postsubiculum in freely moving rats. I. Description and quantitative analysis By www.jneurosci.org Published On :: 1990-02-01 JS TaubeFeb 1, 1990; 10:420-435Articles Full Article
ad Cellular Composition and Three-Dimensional Organization of the Subventricular Germinal Zone in the Adult Mammalian Brain By www.jneurosci.org Published On :: 1997-07-01 Fiona DoetschJul 1, 1997; 17:5046-5061Articles Full Article
ad Broadband Shifts in Local Field Potential Power Spectra Are Correlated with Single-Neuron Spiking in Humans By www.jneurosci.org Published On :: 2009-10-28 Jeremy R. ManningOct 28, 2009; 29:13613-13620BehavioralSystemsCognitive Full Article
ad Adaptive representation of dynamics during learning of a motor task By www.jneurosci.org Published On :: 1994-05-01 R ShadmehrMay 1, 1994; 14:3208-3224Articles Full Article
ad Pax6, Tbr2, and Tbr1 Are Expressed Sequentially by Radial Glia, Intermediate Progenitor Cells, and Postmitotic Neurons in Developing Neocortex By www.jneurosci.org Published On :: 2005-01-05 Chris EnglundJan 5, 2005; 25:247-251BRIEF COMMUNICATION Full Article
ad Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation By www.jneurosci.org Published On :: 1996-03-15 HG KuhnMar 15, 1996; 16:2027-2033Articles Full Article
ad BIRTHDAY PARTY PACKAGE/ DROP-IN LEADERS By www.eastgwillimbury.ca Published On :: Sat, 13 Jul 2019 06:29:34 GMT Full Article
ad Rassegna trimestrale BRI dicembre 2017: Un paradossale inasprimento ci riporta all'enigma del mercato obbligazionario By www.bis.org Published On :: 2017-12-03T17:00:00Z Italian translation of the BIS press release about the BIS Quarterly Review, December 2017 Full Article
ad A fronte della diffusione delle criptovalute, le autorità devono essere pronte ad agire - Agustín Carstens By www.bis.org Published On :: 2018-02-06T09:00:00Z Italian translation of Press Release about BIS General Manager Agustín Carstens giving a speech on "Money in the digital age: what role for central banks?" (6 February 2018) Full Article
ad Informe Trimestral del BPI, marzo de 2018: La volatilidad vuelve a cobrar protagonismo tras un episodio de inestabilidad en los mercados bursátiles By www.bis.org Published On :: 2018-03-11T17:00:00Z Spanish translation of the BIS press release about the BIS Quarterly Review, March 2018 Full Article
ad Las monedas digitales de bancos centrales podrían afectar a los pagos, la política monetaria y la estabilidad financiera By www.bis.org Published On :: 2018-03-12T07:52:00Z Spanish version of Press release about CPMI and the Markets Committee issuing a report on "Central bank digital currencies" (12 March 2018) Full Article
ad Nuevos miembros del Comité de Pagos e Infraestructuras del Mercado By www.bis.org Published On :: 2018-03-19T09:00:00Z Spanish version of Press release about new members joining the Committee on Payments and Market Infrastructures (19 March 2018) Full Article
ad Preguntas frecuentes sobre requerimientos de capital por riesgo de mercado By www.bis.org Published On :: 2018-03-28T13:34:00Z Spanish translation of "Frequently asked questions on market risk capital requirements" by the Basel Committee, March 2018. Full Article
ad Las divergencias se amplían en los mercados: Informe Trimestral del BPI By www.bis.org Published On :: 2018-09-23T16:00:00Z Spanish translation of the BIS press release about the BIS Quarterly Review, September 2018 Full Article
ad Requisitos de divulgación para el Tercer Pilar - Macro actualizado By www.bis.org Published On :: 2018-12-11T10:43:00Z Spanish translation of "Pillar 3 disclosure requirements - updated framework", December 2018 Full Article
ad El Informe Trimestral del BPI analiza la caída y posterior rebote de los mercados By www.bis.org Published On :: 2019-03-05T17:00:00Z Spanish translation of the BIS press release about the BIS Quarterly Review, March 2019 Full Article
ad Pablo Hernández de Cos, nombrado Presidente del Comité de Supervisión Bancaria de Basilea By www.bis.org Published On :: 2019-03-07T12:55:00Z Spanish version of Press release about Pablo Hernández de Cos appointed as Chairman of Basel Committee on Banking Supervision, 7 March 2019. Pablo Hernández de Cos, nombrado Presidente del Comité de Supervisión Bancaria de Basilea. Full Article
ad Oportunidades y riesgos de la entrada de las big tech en el sector financiero By www.bis.org Published On :: 2019-06-23T16:00:00Z Spanish version of BIS Press Release - Big tech in finance: opportunities and risks, 23 June 2019 Full Article
ad Ha llegado la hora de poner en marcha todos los motores By www.bis.org Published On :: 2019-06-30T10:30:00Z Spanish translation of the speech by Mr Agustín Carstens, General Manager of the BIS, on the occasion of the Bank's Annual General Meeting, Basel, 30 June 2019. Full Article
ad Ha llegado la hora de poner en marcha todos los motores, afirma el BPI en su Informe Económico Anual By www.bis.org Published On :: 2019-06-30T10:30:00Z Spanish translation of the BIS press release on the presentation of the Annual Economic Report 2019, 30 June 2019. Full Article
ad Aprendizajes derivados de veinticinco años de autonomía del Banco de México By www.bis.org Published On :: 2019-11-22T14:45:00Z Discurso del Dr. Agustín Carstens, Director General del Banco de Pagos Internacionales, en la Celebración del 25 Aniversario de la Autonomía del Banco de México, Ciudad de México, 22 de noviembre de 2019. Full Article
ad ASÍ QUE LO LOGRASTE QUIÉN IBA A DECIRLO. FELICIDADES Y ¡BIENVENIDO! S V By www.yhchang.com Published On :: Full Article
ad Academy funds three leading engineers to tackle major industry challenges By www.raeng.org.uk Published On :: Mon, 09 Mar 2020 10:29:19 +00:00 Full Article
ad Academy welcomes budget announcements on infrastructure and research By www.raeng.org.uk Published On :: Wed, 11 Mar 2020 16:40:30 +00:00 Full Article
ad Academy responds to novel coronavirus and calls for ideas By www.raeng.org.uk Published On :: Thu, 26 Mar 2020 17:03:57 +00:00 Full Article
ad Academy President comments on postponement of COP26 By www.raeng.org.uk Published On :: Thu, 02 Apr 2020 16:30:00 +01:00 Full Article