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When Stephen Jones get the schedule, he first looks for a three-game road trip

As it turns out, America's Team prefer not to excessively travel the country for which they are named. When fans and media get their eyes on the schedule, they immediately look for certain specific things. During a Friday visit to the PFTPM podcast, Cowboys COO, executive V.P., and director of player personnel Stephen Jones addressed [more]




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Crossing Boundaries—Violation or Obligation?

In this narrative medicine essay, a physician reflects on the rise of professional boundaries; on the ways in which such boundaries can in some instances foster uncaring patient-physician relationships; and on ways physicians might balance providing objective medical care and addressing social and economic injustices in the lives of their patients.




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Aggregation-induced emission luminogens for RONS sensing

J. Mater. Chem. B, 2020, 8,3357-3370
DOI: 10.1039/C9TB02310K, Review Article
Jun Dai, Chong Duan, Yu Huang, Xiaoding Lou, Fan Xia, Shixuan Wang
The development of AIE bioprobes for RONS sensing in living systems is now summarized. We discuss some representative examples of AIEgen based bioprobes in terms of their molecular design, sensing mechanism and sensitive sensing in vitro and in vivo.
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Boosting biomolecular interactions through DNA origami nano-tailored biosensing interfaces

J. Mater. Chem. B, 2020, 8,3606-3615
DOI: 10.1039/C9TB02439E, Paper
Iene Rutten, Devin Daems, Jeroen Lammertyn
Nano-tailored DNA origami designs nanostructure the bioreceptor layer of encoded microparticles in an innovative microfluidic platform, hereby boosting biomolecular interactions.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Novel perylene probe-encapsulated metal–organic framework nanocomposites for ratiometric fluorescence detection of ATP

J. Mater. Chem. B, 2020, 8,3661-3666
DOI: 10.1039/C9TB02319D, Paper
Xiaomeng Zhou, Juanmin Li, Li-Li Tan, Qiang Li, Li Shang
Schematic illustration of PDI@ZIF-8 nanocomposite synthesis and ratiometric fluorescence assay for ATP sensing. 2-MIm: 2-methylimidazole.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Nanomaterial-based gas sensors used for breath diagnosis

J. Mater. Chem. B, 2020, 8,3231-3248
DOI: 10.1039/C9TB02518A, Review Article
Xinyuan Zhou, Zhenjie Xue, Xiangyu Chen, Chuanhui Huang, Wanqiao Bai, Zhili Lu, Tie Wang
Gas-sensing applications commonly use nanomaterials (NMs) because of their unique physicochemical properties, including a high surface-to-volume ratio, enormous number of active sites, controllable morphology, and potential for miniaturisation.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Aqueous surface gels as low friction interfaces to mitigate implant-associated inflammation

J. Mater. Chem. B, 2020, Advance Article
DOI: 10.1039/D0TB00582G, Perspective
Allison L. Chau, Jonah Rosas, George D. Degen, Lisa K. Månsson, Jonathan Chen, Eric Valois, Angela A. Pitenis
Soft implant surfaces should be designed with an eye toward natural, healthy biointerfaces, which use high water content aqueous gel gradients to reduce contact pressures and frictional shear stresses and thus reduce inflammation and discomfort.
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The content of this RSS Feed (c) The Royal Society of Chemistry




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Phosphates-responsive 2D-Metal─Organic-Framework-Nanozymes for Colorimetric Detection of Alkaline Phosphatase

J. Mater. Chem. B, 2020, Accepted Manuscript
DOI: 10.1039/C9TB02542A, Paper
Xiaoyu Wang, Xiaoqian Jiang, Hui Wei
In this study, a simple colorimetric method with tunable dynamic range for alkaline phosphatase (ALP) activity assay was developed by using peroxidase-mimicking two-dimensional-metal─organic-framework (2D-MOF). Phosphates including pyrophosphate (PPi), ATP, and...
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A waterborne polyurethane 3D scaffold containing PLGA with a controllable degradation rate and an anti-inflammatory effect for potential applications in neural tissue repair

J. Mater. Chem. B, 2020, Advance Article
DOI: 10.1039/D0TB00656D, Paper
Bohong Du, Hang Yin, Yue Chen, Weiwei Lin, Yanchao Wang, Daiguo Zhao, Gang Wang, Xueling He, Jiehua Li, Zhen Li, Feng Luo, Hong Tan, Qiang Fu
3D connected porous LGPU scaffolds with adjustable degradation and a strong anti-inflammatory effect were prepared for neural tissue repair.
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Alendronate/folic acid-decorated polymeric nanoparticles for hierarchically targetable chemotherapy against bone metastatic breast cancer

J. Mater. Chem. B, 2020, 8,3789-3800
DOI: 10.1039/D0TB00046A, Paper
Shih-Hong Chen, Te-I Liu, Cheng-Lin Chuang, Hsin-Hung Chen, Wen-Hsuan Chiang, Hsin-Cheng Chiu
Through hierarchically targeting bone matrix and tumor cells, PTX-carrying ALN/FA-nanoparticles substantially accumulate in bone metastases and improve mice survival rate.
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Modified gaphene oxide (GO) particles in peptide hydrogels: a hybrid system enabling scheduled delivery of synergistic combinations of chemotherapeutics

J. Mater. Chem. B, 2020, 8,3852-3868
DOI: 10.1039/D0TB00064G, Paper
John D. Schneible, Kaihang Shi, Ashlyn T. Young, Srivatsan Ramesh, Nanfei He, Clay E. Dowdey, Jean Marie Dubnansky, Radina L. Lilova, Wei Gao, Erik Santiso, Michael Daniele, Stefano Menegatti
Composite material enabling the delivery of synergistic combination of doxorubicin and gemcitabine against breast cancer with molar and kinetic precision.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Human serum albumin-based doxorubicin prodrug nanoparticles with tumor pH-responsive aggregation-enhanced retention and reduced cardiotoxicity

J. Mater. Chem. B, 2020, 8,3939-3948
DOI: 10.1039/D0TB00327A, Paper
Boya Zhang, Shiyu Wan, Xinyu Peng, Mingying Zhao, Sai Li, Yuji Pu, Bin He
A nano-assembly of pH-sensitive doxorubicin prodrug and human serum albumin shows tumor pH-responsive aggregation, enhanced tumor retention and reduced cytotoxicity.
The content of this RSS Feed (c) The Royal Society of Chemistry




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H2S-Donating trisulfide linkers confer unexpected biological behaviour to poly(ethylene glycol)–cholesteryl conjugates

J. Mater. Chem. B, 2020, 8,3896-3907
DOI: 10.1039/C9TB02614B, Paper
Francesca Ercole, Yuhuan Li, Michael R. Whittaker, Thomas P. Davis, John F. Quinn
A comprehensive in vitro study into trisulfide-bearing PEG-conjugates was conducted. For these materials the combination of a cholesteryl group and an H2S donating moiety is required to confer cytoprotective and ROS-mitigating effects.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Discrimination of cysteamine from mercapto amino acids through isoelectric point-mediated surface ligand exchange of β-cyclodextrin-modified gold nanoparticles

J. Mater. Chem. B, 2020, Advance Article
DOI: 10.1039/D0TB00462F, Paper
Quanbao Ma, Xun Fang, Junting Zhang, Lili Zhu, Xiabing Rao, Qi Lu, Zhijun Sun, Huan Yu, Qunlin Zhang
A pI-mediated R6G-β-CD@AuNPs system was designed for the first time for the discrimination of CA from GSH/Cys/Hcy in human serum samples.
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Nanoscale dual-enzyme cascade metal–organic frameworks through biomimetic mineralization as ROS generators for synergistic cancer therapy

J. Mater. Chem. B, 2020, Advance Article
DOI: 10.1039/D0TB00357C, Paper
Shuiling Jin, Lanling Weng, Zhi Li, Zhenzhen Yang, Lili Zhu, Jianxiang Shi, Wenxue Tang, Wang Ma, Hong Zong, Wei Jiang
Chemodynamic therapy (CDT) has been critically challenged by insufficient H2O2 in cancer tissues and inefficient reactive oxygen species (ROS) production.
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One-pot synthesis of trypsin-based magnetic metal–organic frameworks for highly efficient proteolysis

J. Mater. Chem. B, 2020, Advance Article
DOI: 10.1039/C9TB02315A, Paper
Chao Zhong, Zhixian Lei, Huan Huang, Mingyue Zhang, Zongwei Cai, Zian Lin
A facile approach was developed for one-pot synthesis of trypsin-based magnetic ZIF-8, which could be applied as an immobilized enzyme microreactor for rapid digestion of proteins.
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Regulation of cell binding and entry by DNA origami mediated spatial distribution of aptamers

J. Mater. Chem. B, 2020, Advance Article
DOI: 10.1039/D0TB00663G, Communication
Ke Liu, Cong Xu, Jinyao Liu
Customizing the spatial distribution of aptamers on DNA origami nanoboxes can regulate the internalization and proliferation of cancer cells.
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Covalent Organic Framework as Nanocarrier for Synergistic Phototherapy and Immunotherapy

J. Mater. Chem. B, 2020, Accepted Manuscript
DOI: 10.1039/D0TB00679C, Paper
Ying Zhou, Sainan Liu, Chunling Hu, Lihan Cai, Maolin Pang
As traditional cancer treatment methods, photodynamic therapy (PDT) and photothermal therapy (PTT) can eliminate primary tumor, but can't inhibit tumor extensive metastasis and local recurrence. Herein, in order to prevent...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Br(e)aking the news : journalism, politics and new media / Janey Gordon, Paul Rowinski and Gavin Stewart (eds)




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Digital innovations for mass communications : engaging the user / Paul Martin Lester

Lester, Paul Martin, author




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Engaging with reality : documentary and globalization / Ib Bondebjerg

Bondebjerg, Ib




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The news gap : when the information preferences of the media and the public diverge / Pablo Javier Boczkowski and Eugenia Mitchelstein

Boczkowski, Pablo J




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Amateur media : social, cultural and legal perspectives / edited by Dan Hunter, Ramon Lobato, Megan Richardson and Julian Thomas




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Kerry Stokes : self-made man / Margaret Simons

Simons, Margaret, 1960- author




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Grammar matters / Margaret Zeegers

Zeegers, Margaret, author




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Working grammar : an introduction for secondary English teachers / Sally Humphrey, Kristina Love, Louise Droga

Humphrey, Sally, author




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Curiosity : stories of those who report during wartime / written by Jennet Cole-Adams and Judy Gauld

Cole-Adams, Jennet, author




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Gatewatching and news curation : journalism, social media, and the public sphere / Axel Bruns

Bruns, Axel, 1970- author




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Pharmaceutical manufacturing handbook : production and processes / [edited by] Shayne Cox Gad




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Pharmacy management : essentials for all practice settings / [edited by] Shane P. Desselle, David P. Zgarrick




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Molecular targets and therapeutic uses of spices : modern uses for ancient medicine / Bharat B. Aggarwal, Ajaikumar B. Kunnumakkara [editors]




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New developments in medicinal chemistry / Marta P. Ortega and Irene C. Gil, editors




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New generation vaccines / editor-in-chief, Myron M. Levine ; editors, Gordon Dougan ... [et al.]




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Textbook of drug design and discovery / edited by Povl Krogsgaard-Larsen, Kristian Strømgaard, Ulf Madsen




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Wilson and Gisvold's textbook of organic medicinal and pharmaceutical chemistry




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Inorganic drugs in deficiency and disease / edited by Helmut Sigel ; with the assistance of Astrid Sigel




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Frequently prescribed medications : drugs you need to know / [edited by] Michael A. Mancano and Jason C. Gallagher




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Pharmacology in nursing : Australia and New Zealand / Bonita E. Broyles, RN, BSN, EdD, PhD, Barry S. Reiss, BS, MS, PhD, Mary E. Evans, BSEd, MSN, PhD, RN, FAAN, Gayle McKenzie, M (Ed), Grad Dip Adv. Nurs (Critical Care, Grad Cert Ad. Nurs. (Clinical Ed),

Broyles, Bonita E




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Statistical methods for immunogenicity assessment / Harry Yang, Jianchun Zhang, Binbing Yu, Wei Zhao, MedImmune, LLC, Gaithersburg, Maryland, USA

Yang, Harry, author




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A comprehensive guide to toxicology in nonclinical drug development / edited by Ali Said Faqi, DVM, PhD, DABT, (Fellow ATS Senior Director MPI Research, Mattawan, Michigan, United States, Wayne State Univeristy, Detroit, Michigan, United States)




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Immunopotentiators in modern vaccines / edited by Virgil E.J.C. Schijns (Wageningen University, Wageningen, The Netherlands), Derek T. O'Hagan (GSK Vaccines, Rockville, MD, United States)




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The inhibitor index : a desk reference on enzyme inhibitors, receptor antagonists, drugs, toxins, poisons, & therapeutic leads / Daniel L. Purich (Department of Biochemistry & Molecular Biology, University of Florida College of Medicine, Gainesvil

Purich, Daniel L., author




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Cannabis : medical aspects / Blair Henry, Arnav Agarwal, Edward Chow, Hatim A. Omar and Joav Merrick, editors




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Frequently prescribed medications : drugs you need to know / [edited by] Michael A. Mancano, PharmD, Jason C. Gallagher, PharmD




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The obelisk gate / N.K. Jemisin

Jemisin, N. K., author




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The megaflow manifesto : a publication of Nomads of the Time Streams, the International Michael Moorcock Appreciation Society




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Gambit




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Megazine




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The fatal gate / Ian Irvine

Irvine, Ian, 1950- author




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Zombies versus the Antichrist : the walking dead against the Antichrist / a novel by David Peter Ehrlich

Ehrlich, David Peter, 1959- author