A fossil of a tadpole from Argentina is 161 million years old - and isn't that different from some modern species

DNA analysis suggests Pando, a quaking aspen in Utah with thousands of stems connected by their roots, is between 16,000 and 81,000 years old

Genetic analysis of 50,000-year-old Neanderthal skeletons has uncovered the remnants of three viruses related to modern human pathogens, and the researchers think they could be recreated

An experiment inspired by Homer’s description of combat in The Iliad tested the capabilities of the Dendra armour suit from Greece’s Bronze Age

Cut marks on a 4000-year-old skull suggest ancient Egyptian doctors tried to treat a man with nasopharyngeal cancer

An urn found in a tomb in Spain contained the cremated remains of a man, a gold ring and about 5 litres of liquid, which has been identified as now-discoloured white wine

A new radiometric dating technique reveals that cave paintings on Sulawesi, Indonesia, are even older than previously thought, pushing back the earliest evidence of storytelling

DNA and protein analysis has identified a white substance smeared on mummies in China as a kind of kefir cheese, made from cow and goat milk

The Sverris saga describes how castle invaders “took a dead man and cast him unto the well, and then filled it up with stones”, in what may have been an early act of biological warfare - and now researchers believe they have found the skeleton of the man in question

Title: Most Older Adults Plan to Travel Soon, With Precautions: Poll
Category: Health News
Created: 11/17/2021 12:00:00 AM
Last Editorial Review: 11/17/2021 12:00:00 AM

Title: AHA News: Study of Sleep in Older Adults Suggests Nixing Naps, Striving for 7-9 Hours a Night
Category: Health News
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Title: Prior Fractures Could Raise Older Women's Odds for Osteoporosis
Category: Health News
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Title: Midlife Fitness May Mean Healthier Old Age, Study Finds
Category: Health News
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Category: Health News
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Title: 4 Eating Habits May Help Older Women Maintain Weight Loss
Category: Health News
Created: 8/28/2012 2:05:00 PM
Last Editorial Review: 8/29/2012 12:00:00 AM

Title: Healthy Living in Old Age Can Add 6 Years to Life
Category: Health News
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Title: Start School Later for Older Kids, Pediatricians Urge
Category: Health News
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Title: Ebola: A Medical Drama Unfolds
Category: Health News
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Title: Deep Brain Stimulation Safe for Older Parkinson's Patients: Study
Category: Health News
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Category: Health News
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Title: Can Breast Cancer Be a Risk Factor for Opioid Use Among Older Patients?
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Category: Health News
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Category: Health News
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Title: goldenseal
Category: Medications
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Title: Helping Older Loved Ones in a Heat Wave
Category: Health News
Created: 7/25/2022 12:00:00 AM
Last Editorial Review: 7/25/2022 12:00:00 AM

Title: Cold, Flu, Allergy Treatments
Category: Diseases and Conditions
Created: 9/24/1999 12:00:00 AM
Last Editorial Review: 7/15/2022 12:00:00 AM

Extract

We read with great interest the review article by Randerath et al. [1] recently published in the European Respiratory Review. We would like to congratulate the authors on this clearly structured review, which emphasises the urgent need for an increasingly differentiated view of central sleep apnoea (CSA) in the context of precision medicine.

Understanding the evolution of chromatin conformation among species is fundamental to elucidate the architecture and plasticity of genomes. Nonrandom interactions of linearly distant loci regulate gene function in species-specific patterns, affecting genome function, evolution, and, ultimately, speciation. Yet, data from nonmodel organisms are scarce. To capture the macroevolutionary diversity of vertebrate chromatin conformation, here we generate de novo genome assemblies for two cryptodiran (hidden-neck) turtles via Illumina sequencing, chromosome conformation capture, and RNA-seq: Apalone spinifera (ZZ/ZW, 2n = 66) and Staurotypus triporcatus (XX/XY, 2n = 54). We detected differences in the three-dimensional (3D) chromatin structure in turtles compared to other amniotes beyond the fusion/fission events detected in the linear genomes. Namely, whole-genome comparisons revealed distinct trends of chromosome rearrangements in turtles: (1) a low rate of genome reshuffling in Apalone (Trionychidae) whose karyotype is highly conserved when compared to chicken (likely ancestral for turtles), and (2) a moderate rate of fusions/fissions in Staurotypus (Kinosternidae) and Trachemys scripta (Emydidae). Furthermore, we identified a chromosome folding pattern that enables "centromere–telomere interactions" previously undetected in turtles. The combined turtle pattern of "centromere–telomere interactions" (discovered here) plus "centromere clustering" (previously reported in sauropsids) is novel for amniotes and it counters previous hypotheses about amniote 3D chromatin structure. We hypothesize that the divergent pattern found in turtles originated from an amniote ancestral state defined by a nuclear configuration with extensive associations among microchromosomes that were preserved upon the reshuffling of the linear genome.

Background:

The COVID-19 pandemic social distancing requirements encouraged patients to avoid public spaces including in-office health care visits. Ambulatory-care-sensitive conditions (ACSCs) represent conditions that can be managed with quality primary care and when access is limited, these conditions can lead to avoidable emergency department (ED) visits.

BACKGROUND AND PURPOSE:

There has been a distinction made in the 2001 Canadian C-Spine Rule regarding patients 65 and older and younger than 65 years of age as far as indications for cervical spine CT scanning. We sought to determine if there are differences in the symptoms, mechanisms of injury, fracture locations, and types that are still relevant in 2024.

T-lymphoblastic lymphoma (T-LLy) is the most common lymphoblastic lymphoma in children and often presents with a mediastinal mass. Lymphomatous suprarenal masses are possible but rare. Here, we discuss the case of a previously healthy 3-yr-old male who presented with mediastinal T-LLy with bilateral suprarenal masses. Following initial treatment, surgical biopsy of persisting adrenal masses revealed bilateral neuroblastoma (NBL). A clinical genetics panel for germline cancer predisposition did not identify any pathogenic variants. Combination large panel (864 genes) profiling analysis in the context of a precision oncology study revealed two novel likely pathogenic heterozygous variants: SMARCA4 c.1420-1G > T p.? and EZH2 c.1943G > C p.(Ile631Phefs*44). Somatic analysis revealed potential second hits/somatic variants in EZH2 (in the T-LLy) and a segmental loss in Chromosome 19p encompassing SMARCA4 (in the NBL). Synchronous cancers, especially at a young age, warrant genetic evaluation for cancer predisposition; enrollment in a precision oncology program assessing germline and tumor DNA can fulfill that purpose, particularly when standard first-line genetic testing is negative and in the setting of tumors that are not classic for common cancer predisposition syndromes.

Watch President Donald Trump and the Greek prime minister’s joint news conference in the player above.

WASHINGTON — President Donald Trump says the U.S. stands with Greece as they recover from their economic crisis. He is speaking with Prime Minister Alexis Tsipras at the White House in a joint news conference.

The U.S. president says the two leaders have discussed defense, energy, commerce and trade.

Trump is praising Greece for its defense spending under NATO and is noting a potential sale to Greece to upgrade its F-16 aircraft, which he says would be worth up to $2.4 billion and generate thousands of U.S. jobs.

Tsipras says his country has made economic strides and is “leaving behind the economic model that led to the crisis.” He says Greece’s relationship with the U.S. is “more important than ever.”

The post WATCH: Trump and Greek prime minister hold joint news conference appeared first on PBS NewsHour.