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Embryologie und Infections-Krankheits-Uebertragung, sowie die Blutserum-Therapie / von Heinrich Janke.

Berlin : Heuser, 1894.




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An ensemble of Burmese musicians playing traditional instruments at a local funeral. Wood engraving after H.G. Robley.




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An ensemble of Burmese musicians playing traditional instruments at a local funeral. Wood engraving after H.G. Robley.




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National transportation safety board public forum on alcohol and drug safety education.

Springfield, Virginia : National Technical Information Service, 1986.




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Generalised cepstral models for the spectrum of vector time series

Maddalena Cavicchioli.

Source: Electronic Journal of Statistics, Volume 14, Number 1, 605--631.

Abstract:
The paper treats the modeling of stationary multivariate stochastic processes via a frequency domain model expressed in terms of cepstrum theory. The proposed model nests the vector exponential model of [20] as a special case, and extends the generalised cepstral model of [36] to the multivariate setting, answering a question raised by the last authors in their paper. Contemporarily, we extend the notion of generalised autocovariance function of [35] to vector time series. Then we derive explicit matrix formulas connecting generalised cepstral and autocovariance matrices of the process, and prove the consistency and asymptotic properties of the Whittle likelihood estimators of model parameters. Asymptotic theory for the special case of the vector exponential model is a significant addition to the paper of [20]. We also provide a mathematical machinery, based on matrix differentiation, and computational methods to derive our results, which differ significantly from those employed in the univariate case. The utility of the proposed model is illustrated through Monte Carlo simulation from a bivariate process characterized by a high dynamic range, and an empirical application on time varying minimum variance hedge ratios through the second moments of future and spot prices in the corn commodity market.




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Personalized food intervention and therapy for autism spectrum disorder management

9783030304027 (electronic bk.)




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Management of fractured endodontic instruments : a clinical guide

9783319606514 (electronic bk.)




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Instruments for health surveys in children and adolescents

9783319988573 (electronic bk.)




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As Trump returns to the road, some Democrats want to bust Biden out of his basement

While President Donald Trump traveled to the battleground state of Arizona this week, his Democratic opponent for the White House, Joe Biden, campaigned from his basement as he has done throughout the coronavirus pandemic. The freeze on in-person campaigning during the outbreak has had an upside for Biden, giving the former vice president more time to court donors and shielding him from on-the-trail gaffes. "I personally would like to see him out more because he's in his element when he's meeting people," said Tom Sacks-Wilner, a fundraiser for Biden who is on the campaign's finance committee.





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‘Selfish, tribal and divided’: Barack Obama warns of changes to American way of life in leaked audio slamming Trump administration

Barack Obama said the “rule of law is at risk” following the justice department’s decision to drop charges against former Trump advisor Mike Flynn, as he issued a stark warning about the long-term impact on the American way of life by his successor.





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Two-Sample Instrumental Variable Analyses Using Heterogeneous Samples

Qingyuan Zhao, Jingshu Wang, Wes Spiller, Jack Bowden, Dylan S. Small.

Source: Statistical Science, Volume 34, Number 2, 317--333.

Abstract:
Instrumental variable analysis is a widely used method to estimate causal effects in the presence of unmeasured confounding. When the instruments, exposure and outcome are not measured in the same sample, Angrist and Krueger ( J. Amer. Statist. Assoc. 87 (1992) 328–336) suggested to use two-sample instrumental variable (TSIV) estimators that use sample moments from an instrument-exposure sample and an instrument-outcome sample. However, this method is biased if the two samples are from heterogeneous populations so that the distributions of the instruments are different. In linear structural equation models, we derive a new class of TSIV estimators that are robust to heterogeneous samples under the key assumption that the structural relations in the two samples are the same. The widely used two-sample two-stage least squares estimator belongs to this class. It is generally not asymptotically efficient, although we find that it performs similarly to the optimal TSIV estimator in most practical situations. We then attempt to relax the linearity assumption. We find that, unlike one-sample analyses, the TSIV estimator is not robust to misspecified exposure model. Additionally, to nonparametrically identify the magnitude of the causal effect, the noise in the exposure must have the same distributions in the two samples. However, this assumption is in general untestable because the exposure is not observed in one sample. Nonetheless, we may still identify the sign of the causal effect in the absence of homogeneity of the noise.




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Brain-Derived Neurotrophic Factor Protection of Cortical Neurons from Serum Withdrawal-Induced Apoptosis Is Inhibited by cAMP

Steven Poser
Jun 1, 2003; 23:4420-4427
Cellular




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president trump




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The inflation conundrum in advanced economies and a way out

Paper by Mr Luiz Awazu Pereira da Silva, Deputy General Manager of the BIS, Enisse Kharroubi, Emanuel Kohlscheen and Benoît Mojon based on remarks at the University of Basel, 5 May 2019.




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The Coronavirus Is Coming for Trump’s Presidency

Will a nationalist president be undone by his underreaction to a foreign threat?




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Let’s Call It Trumpvirus

If you’re feeling awful, you know who to blame.




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Is It Time to Give Trump a Grade?

Well, there’s always the good old “incomplete.”




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Well, at Least Trump Hasn’t …

Always look on the bright side of life.




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Trump Hates Having Too Many Voters

Suddenly, the White House loves Bernie Sanders.




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Trump’s Flounder Period

What this country needs is another group with a very long name.




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Why the Trump Ploy Stopped Working

As the nation unifies, divisiveness falls flat.




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Some White House staff to wear masks after valet tests positive: Trump – Times of India

  1. Some White House staff to wear masks after valet tests positive: Trump  Times of India
  2. U.S. President Trump says will be tested for coronavirus daily  The Hindu
  3. US VP Mike Pence’s staffer, married to a Trump aide, tests positive for Covid-19  Livemint
  4. Trump's U-turn on the coronavirus task force wasn't really a U-turn at all  The Independent
  5. Aide to Vice President Pence tests positive for coronavirus  Times of India
  6. View Full coverage on Google News



  • IMC News Feed

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Stop Airing Trump’s Briefings!

The media is allowing disinformation to appear as news.




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For Trump, Lying Is a Super Power

He will use deception to keep his bungled response to Covid-19 from ruining his re-election chances.




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Trump’s Dow-at-30,000 Dream Hurt America

Trump is Mark Twain’s king, the great American con man.




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Trump administration shelves expert guidelines on reopening U.S. economy

Documents created by the top disease investigators in the U.S. meant to give step-by-step advice to local leaders deciding when and how to reopen public places such as mass transit, day care centres and restaurants during the still-raging pandemic have been shelved by the Trump administration.




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We’re Relying on Trump to Care About Our Lives

Will he, given his obsession with the economy?




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Should Biden Freak Out About the Trump Bump?

He’s a nominee in perpetual waiting.




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Has Anyone Found Trump’s Soul? Anyone?

He’s not rising to the challenge of the coronavirus pandemic. He’s shriveling into nothingness.




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The Unholy Alliance of Trump and Dr. Oz

They’re pandemic partners, and that’s double trouble.




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Injections of Bleach? Beams of Light? Trump Is Self-Destructing Before Our Eyes

The notion that he is bound for four more years is pure superstition.




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Trump’s Deadly Search for a Scapegoat

If the president had listened to the World Health Organization, American lives would have been saved.




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Trump Makes Us Ill

Going viral is not a good thing this time.




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Trump’s Crazy Fantasy World

In what The Spectator calls “the Year of the Drunken Uncle,” three old guys vie for the presidency amid coronavirus fears and a careering stock market.




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Trump and His Infallible Advisers

Beware men who never admit having been wrong.




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Rumored 'Powerbeats Pro 2' could be minor update to Powerbeats Pro



A pair of model numbers recently discovered in multiple international regulatory filings hinted at a next-generation Beats headphone, but new information suggests the device may actually be related to an existing product that's already in circulation.




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Rumor: 'watchOS 7' could help Apple Watch detect panic attacks



Apple is supposedly developing new mental health features for the Apple Watch line that allow the wearable to detect panic attacks, with the capability potentially slated for launch with a next-generation "watchOS 7" this fall.




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Is Donald Trump Serious?

He says yes. His positions on the issues suggest otherwise.




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An Open Letter to President Trump

The nation craves a plan, not hunches.




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With the Coronavirus, It’s Again Trump vs. Mother Nature

The president’s failure to understand his limits is very costly.




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Trump Is Asking Us to Play Russian Roulette With Our Lives

Are we really going to bet that we can go back to life as normal without proper coronavirus tracking in place?




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We Need Herd Immunity From Trump and the Coronavirus

It will take more care than the president is currently demonstrating to loosen restrictions but still protect the vulnerable.




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Instruments of God in Mexico

New OM team members feel encouraged to be an instrument of God in Mexico.




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Factors Associated With Seizure Onset in Children With Autism Spectrum Disorder

BACKGROUND AND OBJECTIVES:

Children with autism spectrum disorder (ASD) have a higher prevalence of epilepsy compared with general populations. In this pilot study, we prospectively identified baseline risk factors for the development of seizures in individuals with ASD and also identified characteristics sensitive to seizure onset up to 6 years after enrollment in the Autism Speaks Autism Treatment Network.

METHODS:

Children with ASD and no history of seizures at baseline who either experienced onset of seizures after enrollment in the Autism Treatment Network or remained seizure free were included in the analysis.

RESULTS:

Among 472 qualifying children, 22 (4.7%) experienced onset of seizures after enrollment. Individuals who developed seizures after enrollment exhibited lower scores at baseline on all domains of the Vineland Adaptive Behavior Scales, greater hyperactivity on the Aberrant Behavior Checklist (25.4 ± 11.8 vs 19.2 ± 11.1; P = .018), and lower physical quality of life scores on the Pediatric Quality of Life Inventory (60.1 ± 24.2 vs 76.0 ± 18.2; P < .001). Comparing change in scores from entry to call-back, adjusting for age, sex, length of follow-up, and baseline Vineland II composite score, individuals who developed seizures experienced declines in daily living skills (–8.38; 95% confidence interval –14.50 to –2.50; P = .005). Adjusting for baseline age, sex, and length of follow-up, baseline Vineland II composite score was predictive of seizure development (risk ratio = 0.95 per unit Vineland II composite score, 95% confidence interval 0.92 to 0.99; P = .007).

CONCLUSIONS:

Individuals with ASD at risk for seizures exhibited changes in adaptive functioning and behavior.




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Agitation in Patients With Autism Spectrum Disorder Admitted to Inpatient Pediatric Medical Units

OBJECTIVES:

Our goals for this study were to characterize the frequency of agitation in patients with autism spectrum disorder (ASD) admitted to an inpatient pediatric medical unit and to identify risk factors associated with agitation.

METHODS:

Through a retrospective chart review, we identified every patient between 8 and 19 years of age with a documented ASD diagnosis admitted to a pediatric medical unit over a 5-year period. We performed a detailed review of each admission, with a focus on factors hypothesized to be correlated with risk of agitation.

RESULTS:

One or more episode of agitation occurred during 37 (12.4%) of the 299 admissions and for 31 (18.5%) of the 168 patients who met inclusion criteria. History of agitation (risk ratio 21.9 [95% confidence interval 5.4–88.3] for history of severe agitation; P < .001) and documented sensory sensitivities (risk ratio 2.3 [95% confidence interval 1.3–3.8]; P < .001) were associated with a significantly increased risk of agitation during admission. History of past psychiatric admissions was associated with increased risk before, but not after, controlling for history of agitation and sensory sensitivities. Psychiatric comorbidity, intellectual disability, acute pain on admission, number of preadmission psychotropic medications, Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition ASD diagnosis, age, and sex were not significantly associated with increased risk.

CONCLUSIONS:

Hospitalization can be challenging for patients with ASD. A subset of these patients experience episodes of agitation during admission, posing a safety risk to patients and staff. Characterizing risk factors associated with these behaviors may allow for identification of at-risk patients and guide targeted intervention to prevent negative behavioral outcomes.




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Therapy and Psychotropic Medication Use in Young Children With Autism Spectrum Disorder

BACKGROUND AND OBJECTIVES:

Guidelines suggest young children with autism spectrum disorder (ASD) receive intensive nonpharmacologic interventions. Additionally, associated symptoms may be treated with psychotropic medications. Actual intervention use by young children has not been well characterized. Our aim in this study was to describe interventions received by young children (3–6 years old) with ASD. The association with sociodemographic factors was also explored.

METHODS:

Data were analyzed from the Autism Speaks Autism Treatment Network (AS-ATN), a research registry of children with ASD from 17 sites in the United States and Canada. AS-ATN participants receive a diagnostic evaluation and treatment recommendations. Parents report intervention use at follow-up visits. At follow-up, 805 participants had data available about therapies received, and 613 had data available about medications received.

RESULTS:

The median total hours per week of therapy was 5.5 hours (interquartile range 2.0–15.0), and only 33.4% of participants were reported to be getting behaviorally based therapies. A univariate analysis and a multiple regression model predicting total therapy time showed that a diagnosis of ASD before enrollment in the AS-ATN was a significant predictor. Additionally, 16.3% of participants were on ≥1 psychotropic medication. A univariate analysis and a multiple logistic model predicting psychotropic medication use showed site region as a significant predictor.

CONCLUSIONS:

Relatively few young children with ASD are receiving behavioral therapies or total therapy hours at the recommended intensity. There is regional variability in psychotropic medication use. Further research is needed to improve access to evidence-based treatments for young children with ASD.




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Screening Tools for Autism Spectrum Disorder in Primary Care: A Systematic Evidence Review

CONTEXT:

Recommendations conflict regarding universal application of formal screening instruments in primary care (PC) and PC-like settings for autism spectrum disorder (ASD).

OBJECTIVES:

We systematically reviewed evidence for universal screening of children for ASD in PC.

DATA SOURCES:

We searched Medline, PsychInfo, Educational Resources Informational Clearinghouse, and Cumulative Index of Nursing and Allied Health Literature.

STUDY SELECTION:

We included studies in which researchers report psychometric properties of screening tools in unselected populations across PC and PC-like settings.

DATA EXTRACTION:

At least 2 authors reviewed each study, extracted data, checked accuracy, and assigned quality ratings using predefined criteria.

RESULTS:

We found evidence for moderate to high positive predictive values for ASD screening tools to identify children aged 16 to 40 months and 1 study for ≥48 months in PC and PC-like settings. Limited evidence evaluating sensitivity, specificity, and negative predictive value of instruments was available. No studies directly evaluated the impact of screening on treatment or harm.

LIMITATIONS:

Potential limitations include publication bias, selective reporting within studies, and a constrained search.

CONCLUSIONS:

ASD screening tools can be used to accurately identify percentages of unselected populations of young children for ASD in PC and PC-like settings. The scope of challenges associated with establishing direct linkage suggests that clinical and policy groups will likely continue to guide screening practices. ASD is a common neurodevelopmental disorder associated with significant life span costs.1,2 Growing evidence supports functional gains and improved outcomes for young children receiving intensive intervention, so early identification on a population level is a pressing public health challenge.3,4




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Donald Trump says coronavirus vaccine will be developed ‘by the end of this year’

US President Donald Trump has told a town hall meeting that he thinks a coronavirus vaccine will be developed “by the end of this year”.




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Iain Macwhirter: Super Tuesday will showcase Democrats' dismal failure to take on Donald Trump

Mardi Gras in New Orleans has always had a gothic element. The voodoo culture dates from the African American diaspora, though it’s now mostly for tourists. But this year there was an authentically macabre dimension to Fat Tuesday.




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School Leader on Trump's Education Budget (Video)

Education Week's Andrew Ujifusa hashes out the details of the education budget with Prince George's County, Md., Schools CEO Kevin Maxwell.