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Monocyte Invasion into the Retina Restricts the Regeneration of Neurons from Müller Glia

Endogenous reprogramming of glia into neurogenic progenitors holds great promise for neuron restoration therapies. Using lessons from regenerative species, we have developed strategies to stimulate mammalian Müller glia to regenerate neurons in vivo in the adult retina. We have demonstrated that the transcription factor Ascl1 can stimulate Müller glia neurogenesis. However, Ascl1 is only able to reprogram a subset of Müller glia into neurons. We have reported that neuroinflammation from microglia inhibits neurogenesis from Müller glia. Here we found that the peripheral immune response is a barrier to CNS regeneration. We show that monocytes from the peripheral immune system infiltrate the injured retina and negatively influence neurogenesis from Müller glia. Using CCR2 knock-out mice of both sexes, we found that preventing monocyte infiltration improves the neurogenic and proliferative capacity of Müller glia stimulated by Ascl1. Using scRNA-seq analysis, we identified a signaling axis wherein Osteopontin, a cytokine highly expressed by infiltrating immune cells is sufficient to suppress mammalian neurogenesis. This work implicates the response of the peripheral immune system as a barrier to regenerative strategies of the retina.




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Mission trip outside Russia

A group of Russians participates in an OM Moldova summer outreach for children.




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Empowering sustainable ministries

OM Philippines will host three training sessions this month in an effort to see sustainable, transformational and developmental ministries grow in Cebu City.




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Elazağı trip – God’s timing

Two OMer's plan a trip out to eastern Turkey to share the gospel with the lost, as their plans keep changing along the way.




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Trips around Turkey

Travelling around Turkey, one OM worker shares truth with people in some of the country's least reached provinces.




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Sponsoring food distribution in Kurdistan

Amidst ongoing unrest, OM supports IDP communities by sponsoring food distribution through local partners.




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3 guys, 2 countries, 1 believer

An OM worker shares the gospel with a Syrian in northern Iraq, surprisingly reconnecting with the man months later at his baptism in Sweden.




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Distributing God's love around the clock

In his third update from Serbian/Croatian border, Volker Sachse says that in spite of increasingly difficulties, he can see God’s peace touch local people.




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Israel Navy strikes Hezbollah in Beirut, while spying on distant enemies


The navy has, numerous times in the past, acknowledged that it carries out surveillance of Israel’s enemies, sometimes at a great distance.




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Triumphant Trump returns to White House to meet Biden

Donald Trump will make a triumphant return to the White House to meet President Joe Biden on Wednesday, in the Republican’s first visit since departing amid a cloud of scandal nearly four years ago.

Trump’s meeting with Biden comes as he moves swiftly to name his top team, including the world’s richest man Elon Musk as head of a new group aimed at slashing government waste.

Democrat Biden invited his sworn rival to meet in the Oval Office — despite the fact that Trump, who has consistently refused to admit his 2020 election loss, never afforded Biden the same courtesy.

Biden, 81, is expected to urge a smooth transition of power in the encounter at 11am (1600 GMT) — and push for continued support for Ukraine.

“He believes in the norms. He believes in our institutions,” White House Press Secretary Karine Jean-Pierre said on Tuesday when asked why Biden was inviting Trump.

“The American people deserve this. They deserve a peaceful transfer of power.”

US National Security Advisor Jake Sullivan said Biden would go over top foreign policy issues when he meets Trump — including US support for Kyiv against Russia, which Trump has criticised.

“The president will have the chance to explain to President Trump how he sees things, where they stand, and talk to President Trump about how President Trump is thinking,” Sullivan told CBS on Sunday.

But the meeting may be a bitter pill to swallow for Biden, who branded Trump a threat to democracy and was vying for the presidency against him until a disastrous debate performance forced the Democrat out of the race in July.

House speaker Mike Johnson said Trump may also visit the US Capitol — the building a mob of his supporters stormed in 2021 to try to reverse his election loss — but these plans have not been finalised.

Trump’s party looks set to take both chambers of Congress and consolidate his extraordinary comeback.

Tradition restored

Biden’s Oval Office invitation restores a presidential transition tradition that Trump tore up when he lost the 2020 election, refusing to sit down with Biden or even attend the inauguration.

Then-president Barack Obama had welcomed Trump to the White House when the tycoon won the 2016 election.

But by the time Trump took his last Marine One flight from the White House lawn on January 20, 2021, he had also been repudiated by many in his own party for having encouraged the Capitol riot.

The period of disgrace soon evaporated, however, as Republicans returned to Trump’s side, recognising his unique electoral power at the head of his right-wing movement.

Trump, 78, enters his second term with a near-total grip on his party and the Democrats in disarray.

He has spent the week since the election at his Mar-a-Lago resort in Florida assembling his top team, as the world watches to see how closely he sticks to his pledges of isolationism, mass deportations and sweeping tariffs.

Trump named Space X, Tesla and X boss Musk, and another stalwart ally, businessman Vivek Ramaswamy, to lead a “Department of Government Efficiency (‘DOGE’)” — a tongue-in-cheek reference to an internet meme and cryptocurrency.

In a flurry of announcements, Trump also picked Fox News host and military veteran Pete Hegseth as his incoming defense secretary. Hegseth has been an outspoken opponent of so-called “woke” ideology in the armed forces.

Trump further named South Dakota Governor Kristi Noem — an ally who famously wrote about shooting her dog because it did not respond to training — as head of the Department of Homeland Security.

Florida Senator Marco Rubio is tipped for secretary of state, US media reported, while Trump has also confirmed Congressman Mike Waltz, a former special forces officer, as his national security advisor.

Both have hawkish views on China but are not considered isolationists, despite Trump’s previous threats to retreat from or cut obligations to alliances like the North Atlantic Treaty Organisation (Nato).




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US govt employee indicted for leaking classified documents on Israel’s plans to strike Iran

A US government employee has been indicted for leaking classified national defence information, according to federal court records unsealed on Wednesday.

The indictment, charging Asif William Rahman with two counts of willfully transmitting classified information, does not provide details about the nature of the leak.

However, it says the leak occurred on or about October 17.

That was around the time that a pro-Iranian Telegram account called “Middle East Spectator” published what appeared to be a pair of documents produced by the National Geospatial-Intelligence Agency which shared information about Israel’s preparations for an attack on Iran.

The intelligence in the documents was based on satellite imagery from Oct 15 to 16.

In a previous statement, the Middle East Spectator said it had received the documents through an anonymous source, and that it had no connection to the original leaker nor could it verify the authenticity of the documents.

The FBI in October confirmed it was investigating who had leaked the documents.

According to the indictment, which is dated November 7, investigators believe the leak took place in Cambodia.

Rahman was arrested in Cambodia on Nov 12, and is expected to make an initial court appearance in a federal court in Guam on Nov 14 before he is transferred to stand trial in the Eastern District of Virginia.




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Longleng District Observes World Pneumonia Day - Eastern Mirror

  1. Longleng District Observes World Pneumonia Day  Eastern Mirror
  2. Govt to equip dist hosps to cut child pneumonia deaths  The Times of India
  3. World Pneumonia Day: 7 natural ways to keep your lungs healthy  Health shots
  4. World Pneumonia Day: 9 foods to fight pneumonia  Firstpost
  5. World Pneumonia Day: Three young lives lost daily in Gujarat  Gujarat Samachar




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Predicting paediatric asthma exacerbations with machine learning: a systematic review with meta-analysis

Background

Asthma exacerbations in children pose a significant burden on healthcare systems and families. While traditional risk assessment tools exist, artificial intelligence (AI) offers the potential for enhanced prediction models.

Objective

This study aims to systematically evaluate and quantify the performance of machine learning (ML) algorithms in predicting the risk of hospitalisation and emergency department (ED) admission for acute asthma exacerbations in children.

Methods

We performed a systematic review with meta-analysis, following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The risk of bias and applicability for eligible studies was assessed according to the prediction model study risk of bias assessment tool (PROBAST). The protocol of our systematic review was registered in the International Prospective Register of Systematic Reviews.

Results

Our meta-analysis included seven articles encompassing a total of 17 ML-based prediction models. We found a pooled area under the curve (AUC) of 0.67 (95% CI 0.61–0.73; I2=99%; p<0.0001 for heterogeneity) for models predicting ED admission, indicating moderate accuracy. Notably, models predicting child hospitalisation demonstrated a higher pooled AUC of 0.79 (95% CI 0.76–0.82; I2=95%; p<0.0001 for heterogeneity), suggesting good discriminatory power.

Conclusion

This study provides the most comprehensive assessment of AI-based algorithms in predicting paediatric asthma exacerbations to date. While these models show promise and ML-based hospitalisation prediction models, in particular, demonstrate good accuracy, further external validation is needed before these models can be reliably implemented in real-life clinical practice.




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Hundreds of Bethesda Employees Go on Strike

Hundreds of employees at Bethesda have gone on strike, according to a report from Inverse.

Bethesda employees in Maryland and Texas have claimed the company has not addressed remote work concerns at the bargaining table and has been outsourcing quality assurance work without an agreement with the union.

"I'm excited. I'm really looking forward to tomorrow. I think it's going to be a fun event," said quality assurance test lead Rhyanna Eichner a day before the strike.

"I know that sounds weird, but we're all really looking forward to coming together and spending time together. Everybody understands that this needs to happen. This is what needs to be done to move on. We're all just kind of ready for it."

The union is looking to limit the percentage of quality assurance testers that Bethesda outsources when compares to the number of full-time employees.

The union is also looking for a more flexible remote work policy. Currently ZeniMax employees are required to go to the office twice a week and the union says many employees have been denied remote work requests.

"They have continually given us their first proposal again and again, and it’s become obvious that our different mobilization tactics have not worked," said Eichner.

Senior quality assurance tester at Rockville, Maryland Juniper Dowell added, "Striking isn’t fun or ideal, but there’s a satisfaction in having a concrete physical action we can do to fight for better work conditions. Hopefully, we can convince them to stop dragging their feet and meet us at the table."

A life-long and avid gamer, William D'Angelo was first introduced to VGChartz in 2007. After years of supporting the site, he was brought on in 2010 as a junior analyst, working his way up to lead analyst in 2012 and taking over the hardware estimates in 2017. He has expanded his involvement in the gaming community by producing content on his own YouTube channel and Twitch channel. You can contact the author on Twitter @TrunksWD.

Full Article - https://www.vgchartz.com/article/463058/hundreds-of-bethesda-employees-go-on-strike/





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Gayatri Asokan’s new ghazal draws on poet Jaun Elia’s work

Seven years after transitioning from Malayalam playback to the world of ghazals, Gayatri Asokan is set to release yet another track, ‘Kitne Aish Se Rahte Honge’, inspired by the poetry of Jaun Elia





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Strict action against CAs and agencies who mislead taxpayers

Cities such as Gurugram, Ghaziabad, Mumbai and Bengaluru are being targeted by Income Tax Department.Notices to taxpayers for the 2021-22 and 2022-23 ass




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Poor Culture Severely Affects Attrition Rate in offices of India

Everyone likes to be valued and numerous studies reveal that there is a psychological effect of workplace gratitude and appreciation on an employee.




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Bihar State Industrial Department Receives Over 30 Startup Proposals

According to the startup policy approved by the state cabinet on September 6, Bihar’s state industrial department recently launched a website––biharstartupyatra.com that supports people planning to set up startups in the state.




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5 Startups that are Contributing to Avert the Drastic Effects of Air Pollution

Delhi, with a massive population of about 25.8 million, is ranked 5th among the list of 32 megacities formulated by WHO.




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Facebook Buys Emotion Detection Startup FacioMetrics

Facebook has acquired emotion detection start-up FacioMetrics to push its artificial intelligence (AI) research into building facial gesture controls.




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Juventus striker striker combination fly 25 million penalty actually packed full Bargain repurchase

Two draws a penalty after one win and one loss, Juventus [microblogging] in the TIM Cup triangular tournament still ranks among the newly promoted after the second place, but the Serie A champions lackluster performance in the...




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a bowler could get a winning treasure to suit bowling a strive for


I am not allowing any of this consideration into your warring and in addition what I wish to accomplish, They permanent. McCarron, What kind of person in season will likely among members of the squad reputation between the two...




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Setting up ice production anywhere for ice maker in Southeastern Countries




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Google Will Now Provide Flood Forecasting in 100 Countries

Google announced the expansion of its artificial intelligence (AI) flood forecasting system on Monday. With this expansion, the Mountain View-based tech giant will now cover 100 countries and offer...




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Samsung Tri-Fold Smartphone in Development? Patent Suggests it Will Resemble the Huawei Mate XT

Samsung is reportedly working on a tri-fold smartphone, expected to arrive sometime next year. An earlier report suggested that Samsung display's partners have finished developing components for the tri-fold model. Now, the latest development reveals Samsung has already filed a patent




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Effective Tips For Navigating Traffic On Indian Road Trips

Embarking on a road trip across India can be an exhilarating experience. However, traffic congestion can quickly turn excitement into frustration. For automobile enthusiasts, understanding how to navigate these challenges is crucial. This guide offers insights into avoiding traffic and saving




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Aishwarya Rai and Katrina Kaif lost this blockbuster franchise of Rs 600 crore, were replaced by...

The third instalment of this iconic franchise is running super-strong at the box office. The latest surpassed the previous box office records and became the highest-grossing film of the franchise. Sadly, the original choices of this franchise were Aishwarya Rai and Vidya Balan.




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India's first hydrogen train to start trials soon: Check route, features, top speed to be...

This hydrogen-powered train will be the first in India that will be running on water. Instead of conventional diesel or electric engines, the train uses hydrogen fuel cells to generate the electricity required for movement.




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Napkins and geometry boxes distributed to sanitary workers




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Stringent measures in place to check drug distribution and sale




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Carrier behavior of a carbon material assisted TIPS-pentacene composite film for improvement of electrical conductivity

RSC Adv., 2024, 14,36308-36313
DOI: 10.1039/D4RA06312K, Paper
Open Access
Moonjeong Bok, Ju Ho Lee, Kanghee Won, Eunju Lim
Organic semiconductor devices have a lower intrinsic carrier density than inorganic semiconductors, and improving their electrical conductivity is important for organic electronic devices.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Global outlook on transmission and distribution networks

Emerging Markets and Developing Economies (EMDE) have been driving the growth in electricity grid length with rapid expansion from 2001, on increasing electrification. China leads the incremental transmission network put up in the last decade while India leads on the distribution side. India leads in Technical grid losses in T&D when compared with other countries. High-Voltage Direct Current (HVDC) transmission lines, thus, emerge as the most preferred transmission lines considering their lower losses and their suitability for long-distance power transfer




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13/15:52 CST Fire Weather Warning for Barkly North fire weather district




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Nutrition and Aging

Aging is an inevitable part of life. As the years go by, our bodies undergo various changes, and our nutritional needs evolve. To live a healthy and fulfilling life as you grow older, it’s crucial to pay attention to your diet. Proper nutrition can help you maintain vitality, ward off chronic diseases, and enjoy a […]

The post Nutrition and Aging appeared first on Roads To Iraq - The Cradle of Mankind.




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Implementing Metrics Is Connected But Separate from Choosing Management Style, Company Culture, and Incentives


More often than not in traditional management consulting engagements involving operations, there is usually room for setting up or revising goals, metrics & reporting, and service level agreements. Depending on the phase of development of a company (often couched as Stage 0 [Ad-Hoc], Stage 1 [Functional], Stage 2 [Intrabusiness Cross-Functional], etc. maturity levels by a consulting firm), the next higher-level of metrics and reporting may apply and be a goal for the client organization to strive for.

Where management has to be somewhat careful about applying metrics, however, is how people and company culture play a role in getting everything to work together right.

To put a finer point on things, one can put in place a perfectly appropriate set of metrics and reporting systems for a company yet miss the boat completely on a management-level as to how the results should be applied because of the culture.

As an example in sales operations, I have frequently seen a competitive environment laid out. People's individual performance levels are exposed, and poor performing people are weeded out. This environment can work out in some cases. On the other hand, in a collaborative engineering or product development environment, cooperation may be encouraged.

On a related topic, a friend of my wife and I, Dr. Uri Gneezy at the University of Chicago, has some great research on the relationship between competition and gender. From the research summary:

Gneezy suggests that CEOs creating incentives in their firms should be aware that making the internal environment more competitive might create a bias that helps men, while putting women at a relative disadvantage.

My take on applying this type of research would be to recognize and raise one's sense of awareness to the environment one is implementing metrics in. Although metrics may be encouraged to be tracked to an individual-level doesn't automatically equate to that the environment has to be a competitive one. Choosing a collaborative versus dictatorial management style that is compatible with the desired company culture is a separate choice from metric implementation.

Steve Shu Managing Director S4 Management Group Email: sshu@s4management.com Web: http://www.s4management.com




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The Pierre Statement on Biblical Doctrines by confessing Christians - Contact: David - David_Anson_Brown@Hotmail.com

Note: once the current article 'Areas and Doctrines' is adequately summarized with about 25 Areas and Doctrines that are central and relevant to the Christian faith - The article is going to be made open to participation from others and for group (roundtable) discussion - Then a more finalized version of the article will be published similar to 'The Chicago Statement on Biblical Application' though with the working title of 'The Pierre Statement on Biblical Doctrines' by confessing Christians - The publishing of the document 'The Pierre Statement on Biblical Doctrines' by confessing Christians should be able to be accomplished sometime within 2012 - I'll update the post with an email that people can contact me with regarding the Pierre Statement on Biblical Doctrines - All the best, God bless everyone ~ David Anson Brown




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Wikipedia: Kathryn Kuhlman (1907 - 1976) -- Was an American faith healer and evangelist - Kuhlman [modeling her career in the mold of her idol Aimee Semple McPherson] traveled extensively around the United States and in many other countries holding "

Early life: Kathryn Johanna Kuhlmun was born in Concordia, Missouri, to German-American parents. She was born-again at the age of 13 in the Methodist Church of Concordia, and began preaching in the West at the age of sixteen in primarily Baptist Churches. -- Career: Kuhlman traveled extensively around the United States and in many other countries holding "healing crusades" between the 1940s and 1970s. She had a weekly TV program in the 1960s and 1970s called I Believe In Miracles that was aired nationally. The foundation was established in 1954, and its Canadian branch in 1970. Following a 1967 fellowship in Philadelphia, Dr. William A. Nolen conducted a case study of 23 people who claimed to have been cured during her services. Nolen's long term follow-ups concluded there were no cures in those cases. Furthermore, one woman who was said to have been cured of spinal cancer took off her brace and ran across the stage at Kuhlman's command; her spine collapsed the following day and she died four months later. -- By 1970 she moved to Los Angeles conducting faith healing for thousands of people each day as an heir to Aimee Semple McPherson. She became well-known despite, as she told reporters, having no theological training. In 1935, Kathryn met Burroughs Waltrip, an extremely handsome Texas evangelist who was eight years her senior. Despite the fact that he was married with two small boys, they soon found themselves attracted to each other. Shortly after his visit to Denver, Waltrip divorced his wife, left his family and moved to Mason City, Iowa, where he began a revival center called Radio Chapel. Kathryn and her friend and pianist Helen Gulliford came into town to help him raise funds for his ministry. It was shortly after their arrival that the romance between Burroughs and Kathryn became publicly known. -- Burroughs and Kathryn decided to wed. While discussing the matter with some friends, Kathryn had said that she could not "find the will of God in the matter." These and other friends encouraged her not to go through with the marriage, but Kathryn justified it to herself and others by believing that Waltrip's wife had left him, not the other way around. On October 18th, 1938, Kathryn secretly married "Mister," as she liked to call Waltrip, in Mason City. The wedding did not give her new peace about their union, however. After they checked into their hotel that night, Kathryn left and drove over to the hotel where Helen was staying with another friend. She sat with them weeping and admitted that the marriage was a mistake. She decided to get an annulment. -- In 1975, Kuhlman was sued by Paul Bartholomew, her personal administrator, who claimed she kept $1 million in jewelry and $1 million in fine art hidden away and sued her for $430,500 for breach of contract. Two former associates accused her in the lawsuit of diverting funds and illegally removing records, which she denied and said the records were not private. According to Kuhlman, the lawsuit was settled prior to trial. -- Death and legacy: In July 1975 her doctor diagnosed her with a minor heart flareup and she had a relapse in November while in Los Angeles. As a result, she had open heart surgery in Tulsa, Oklahoma from which she died in February 1976. Kathryn Kuhlman is interred in the Forest Lawn Memorial Park Cemetery in Glendale, California. A plaque in her honor is located in the main city park in Concordia, Missouri, a town located in central Missouri on Interstate Highway 70. -- After she died, her will led to controversy. She left $267,500, the bulk of her estate, to three family members and twenty employees. Smaller bequests were given to 19 other employees. According to the Independent Press-Telegram , her employees were disappointed that "she did not leave most of her estate to the foundation as she had done under a previous 1974 will." The Kathryn Kuhlman Foundation has continued, but in 1982 it terminated its nationwide radio broadcasting. She influenced faith healers Benny Hinn and Billy Burke. Hinn has adopted some of her techniques and wrote a book about her. -- Healing: Many accounts of healings were published in her books, which were "ghost-written" by author Jamie Buckingham of Florida, including her autobiography, which was dictated at a hotel in Las Vegas. Buckingham also wrote his own Kuhlman biography that presented an unvarnished account of her life. Many other faith healers, including Benny Hinn, who have been inspired by Kathryn Kuhlman have faced similar suspicions about their methods and practices.



  • Christian Church History Study
  • 4. 1881 A.D. to Present (2012) - Corrupt modern bible translations and compromised Seminaries and Universities

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Wikipedia: Oxford Martyrs (1555-1556 A.D.) -- The Oxford Martyrs were tried for heresy in 1555 A.D. and subsequently burnt at the stake in Oxford, England, for their religious beliefs and teachings - The three martyrs were the Anglican bishops Hugh Latime

History: The three were tried at University Church of St Mary the Virgin, the official church of Oxford University on the High Street. The martyrs were imprisoned at the former Bocardo Prison near the still extant St Michael at the Northgate church (at the north gate of the city walls) in Cornmarket Street. The door of their cell is on display in the tower of the church. The martyrs were burnt at the stake just outside the city walls to the south, where Broad Street is now located. Latimer and Ridley were burnt on 16 October 1555. Cranmer was burnt five months later on 21 March 1556. A small area cobbled with stones forming a cross in the centre of the road outside the front of Balliol College marks the site. The Victorian spire-like Martyrs' Memorial, at the south end of St Giles' nearby, commemorates the events. It is claimed that the scorch marks from the flames can still be seen on the doors of Balliol College (now rehung between the Front Quadrangle and Garden Quadrangle).



  • Christian Church History Study
  • 3. 1522 A.D. to 1880 A.D. - Indigenous Bible translations and Church Doctrines era - The Reformation

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Wikipedia: Charlemagne (742 - 28 January 814 A.D.), also known as Charles the Great - was King of the Franks [German Tribes] from 768 A.D. - The conquest of Italy brought Charlemagne in contact with the Saracens [Muslims] who, at the time (799 A.D.), cont

Wars with the Moors [Muslims]: The conquest of Italy brought Charlemagne in contact with the Saracens who, at the time, controlled the Mediterranean. Pippin, his son, was much occupied with Saracens in Italy. Charlemagne conquered Corsica and Sardinia at an unknown date and in 799 the Balearic Islands. The islands were often attacked by Saracen pirates, but the counts of Genoa and Tuscany (Boniface) kept them at bay with large fleets until the end of Charlemagne's reign. Charlemagne even had contact with the caliphal court in Baghdad. In 797 (or possibly 801), the caliph of Baghdad, Harun al-Rashid, presented Charlemagne with an Asian elephant named Abul-Abbas and a clock. -- In Hispania [Spain], the struggle against the Moors continued unabated throughout the latter half of his reign. His son Louis was in charge of the Spanish border. In 785, his men captured Gerona permanently and extended Frankish control into the Catalan littoral for the duration of Charlemagne's reign (and much longer, it remained nominally Frankish until the Treaty of Corbeil in 1258). The Muslim chiefs in the northeast of Islamic Spain were constantly revolting against Córdoban authority, and they often turned to the Franks for help. The Frankish border was slowly extended until 795, when Gerona, Cardona, Ausona, and Urgel were united into the new Spanish March, within the old duchy of Septimania. -- In 797 Barcelona, the greatest city of the region, fell to the Franks when Zeid, its governor, rebelled against Córdoba and, failing, handed it to them. The Umayyad authority recaptured it in 799. However, Louis of Aquitaine marched the entire army of his kingdom over the Pyrenees and besieged it for two years, wintering there from 800 to 801, when it capitulated. The Franks continued to press forward against the emir. They took Tarragona in 809 and Tortosa in 811. The last conquest brought them to the mouth of the Ebro and gave them raiding access to Valencia, prompting the Emir al-Hakam I to recognize their conquests in 812 A.D.



  • Christian Church History Study
  • 2. 313 A.D. to 1521 A.D. - Revised Rome and the Holy Roman Empire

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Wikipedia: Jerome - Saint Jerome (347 - 30 September 420) was a Roman Christian priest, confessor, theologian and historian, and who became a Doctor of the Church - He was the son of Eusebius, of the city of Stridon, which was on the border of Dalmatia an

Eusebius Sophronius Hieronymus was born at Stridon around 347. He was not baptized until about 360 or 366, when he had gone to Rome with his friend Bonosus (who may or may not have been the same Bonosus whom Jerome identifies as his friend who went to live as a hermit on an island in the Adriatic) to pursue rhetorical and philosophical studies. He studied under the grammarian Aelius Donatus. There Jerome learned Latin and at least some Greek, though probably not the familiarity with Greek literature he would later claim to have acquired as a schoolboy. As a student in Rome, he engaged in the superficial activities of students there, which he indulged in quite casually but suffered terrible bouts of repentance afterwards. To appease his conscience, he would visit on Sundays the sepulchers of the martyrs and the Apostles in the catacombs. This experience would remind him of the terrors of hell: Often I would find myself entering those crypts, deep dug in the earth, with their walls on either side lined with the bodies of the dead, where everything was so dark that almost it seemed as though the Psalmist's words were fulfilled, Let them go down quick into Hell. Here and there the light, not entering in through windows, but filtering down from above through shafts, relieved the horror of the darkness. But again, as soon as you found yourself cautiously moving forward, the black night closed around and there came to my mind the line of Vergil, "Horror unique animos, simul ipsa silentia terrent. Jerome used a quote from Vergil - "The horror and the silences terrified their souls" - to describe the horror of hell. Jerome initially used classical authors to describe Christian concepts such as hell that indicated both his classical education and his deep shame of their associated practices, such as pederasty. Although initially skeptical of Christianity, he was eventually converted. After several years in Rome, he travelled with Bonosus to Gaul and settled in Trier where he seems to have first taken up theological studies, and where he copied, for his friend Tyrannius Rufinus, Hilary of Poitiers' commentary on the Psalms and the treatise De synodis. Next came a stay of at least several months, or possibly years, with Rufinus at Aquileia, where he made many Christian friends. Some of these accompanied him when he set out about 373 on a journey through Thrace and Asia Minor into northern Syria. At Antioch, where he stayed the longest, two of his companions died and he himself was seriously ill more than once. During one of these illnesses (about the winter of 373-374), he had a vision that led him to lay aside his secular studies and devote himself to God. He seems to have abstained for a considerable time from the study of the classics and to have plunged deeply into that of the Bible, under the impulse of Apollinaris of Laodicea, then teaching in Antioch and not yet suspected of heresy. ... The works of Hippolytus of Rome and Irenaeus greatly influenced Jerome's interpretation of prophecy. He noted the distinction between the original Septuagint and Theodotion's later substitution. Jerome warned that those substituting false interpretations for the actual meaning of Scripture belonged to the "synagogue of the Antichrist". "He that is not of Christ is of Antichrist," he wrote to Pope Damasus I. **He believed that "the mystery of iniquity" written about by Paul in 2 Thessalonians 2:7 was already in action when "every one chatters about his views." To Jerome, the power restraining this mystery of iniquity was the Roman Empire, but as it fell this restraining force was removed. He warned a noble woman of Gaul: "He that letteth is taken out of the way, and yet we do not realize that Antichrist is near. Yes, Antichrist is near whom the Lord Jesus Christ "shall consume with the spirit of his mouth." "Woe unto them," he cries, "that are with child, and to them that give suck in those days."... Savage tribes in countless numbers have overrun all parts of Gaul. The whole country between the Alps and the Pyrenees, between the Rhine and the Ocean, has been laid waste by hordes of Quadi, Vandals, Sarmatians, Alans, Gepids, Herules, Saxons, Burgundians, Allemanni, and-alas! for the commonweal!-- even Pannonians. His Commentary on Daniel was expressly written to offset the criticisms of Porphyry, who taught that Daniel related entirely to the time of Antiochus IV Epiphanes and was written by an unknown individual living in the 2nd century BC. Against Porphyry, Jerome identified Rome as the fourth kingdom of chapters two and seven, but his view of chapters eight and 11 was more complex. Jerome held that chapter eight describes the activity of Antiochus Epiphanes, who is understood as a "type" of a future antichrist; 11:24 onwards applies primarily to a future antichrist but was partially fulfilled by Antiochus. Instead, he advocated that the "little horn" was the Antichrist: We should therefore concur with the traditional interpretation of all the commentators of the Christian Church, that at the end of the world, when the Roman Empire is to be destroyed, there shall be ten kings who will partition the Roman world amongst themselves. Then an insignificant eleventh king will arise, who will overcome three of the ten kings... after they have been slain, the seven other kings also will bow their necks to the victor. In his Commentary on Daniel, he noted, "Let us not follow the opinion of some commentators and suppose him to be either the Devil or some demon, but rather, one of the human race, in whom Satan will wholly take up his residence in bodily form." In interpreting 2 Thessalonians's claim that the Antichrist will sit in God's temple, Jerome preferred the view that the "temple" should be interpreted as the Church, not as the Temple in Jerusalem. Jerome identified the four prophetic kingdoms symbolized in Daniel 2 as the Neo-Babylonian Empire, the Medes and Persians, Macedon, and Rome. Jerome identified the stone cut out without hands as "namely, the Lord and Savior". Jerome refuted Porphyry's application of the little horn of chapter seven to Antiochus. He expected that at the end of the world, Rome would be destroyed, and partitioned among ten kingdoms before the little horn appeared. Jerome believed that Cyrus of Persia is the higher of the two horns of the Medo-Persian ram of Daniel 8:3. The he-goat is Greece smiting Persia. Alexander [the Great] is the great horn, which is then succeeded by Alexander's half brother Philip and three of his generals.



  • Christian Church History Study
  • 2. 313 A.D. to 1521 A.D. - Revised Rome and the Holy Roman Empire

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{Basic Christian: The 8 Kingdoms study} Alpha & Omega Ministries Apologetics Blog - I have been downright encouraged to note the response that has appeared to the amazing statements of James McDonald of "Vertical Church" wherein he basically

But even more importantly than the tweaking of Modalism so that it gets a place at the table is the attitude McDonald has displayed toward the Nicene definition. He says he does not trace his beliefs to credal statements. Really? If by that he means creeds are always subject to the higher authority of Scripture, of course. But this is where you fall off the other side of the narrow path and rather than believing in sola scriptura, you end up with something much less, and in fact, much different. Nicea's authority comes from its fidelity to Scripture. It does not stand alone as a new revelation, and it survived simply because it is, despite all the arguments to the contrary, the consistent, harmonious testimony of divine writ. To throw its authority into the dustbin of history in the service of some kind of "emergent" attitude is not only to display an astoundingly arrogant hubris, it is to show deep disrespect to those who fought, and some who died, in defense of its truth. And for what? For some kind of post-modern feel-goodism that cannot even recognize modalism when it is standing right in front of you. A truly educational example of just how far the emergent movement is willing to go in pursuit of its ultimately destructive goals. -- Recently Jamin Hubner has raised issues relating to a simple question: is the modern secular state of Israel religiously and theologically significant? Is it "Israel" as in the Israel of Scripture, or Romans 11? And if it is not, is it open to criticism? He is concerned about the strength of the movement, mainly amongst American evangelicals, that has granted to Israel not only a theological position it does not actually hold, but which precludes even the slightest mention of criticism of a secular state. Now, I am not going to re-hash everything here, but he has even been accused of being a "shill for Hamas" due to sources he has cited and issues he has raised (which seems to me to provide strong evidence of the need to raise such issues and challenge the knee-jerk reactions of many in the Evangelical community as a whole). While he has sought fair and non-emotional responses to questions he has raised, his requests have, in the main, fallen upon deaf ears, for I see no evidence that his critics really want to have a give-and-take.



  • Christian Church History Study
  • 1. 0 A.D. to 312 A.D. - Birth of Jesus and the early Church Age

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{Basic Christian: blog Bible Study} The Apostle Paul - When Paul became a Christian, his very thorough [Jewish] education was enormously helpful - He was able to assimilate Christian doctrines rapidly and relate them accurately to the Scripture teaching h

The Apostle Paul - The apostle Paul was one of the most famous citizens of the Roman Empire and without question one of the most influential individuals in history. He was used by the Lord in his missionary and evangelistic activities to set in motion a great deal of the organization known as the Christian Church, the Body of Christ on earth, to the extent that billions of human beings have been directly or indirectly affected by his ministry. Under the inspiration of the Holy Spirit, he wrote the foundation documents for the Christian way of life, the Word of God which has changed the lives of millions. -- Paul's Education: Paul was educated by his mother until the age of five. From age five to ten he studied with his father in the Hebrew scriptures and traditional writings. At the same time, being a Roman citizen and living in a Greek and Roman environment, he received a thorough education in the Greek language, history, and culture. He was sent to Jerusalem at about the age of ten to attend the rabbinical school of Gamaliel, who was the son of Simeon the son of Hillel. Gamaliel was a most eminent rabbi who was mentioned both in the Talmud and in the New Testament (Acts 5:24-40; 22:3). Gamaliel was called Rabban - one of only seven teachers so called. He was a Pharisee, but he rose above party prejudice. He composed a prayer against the Christian "heretics". He lived and died a Jew. At this time, Herod was dead, and the Romans had complete control of Judea, hence, there was Roman money, language, and culture. The Jews, therefore, were inclined to cling more closely to their religion as the center of unity. [Refer to the topic: Judean History] There were two great rabbinical schools, those of Hillel and Schammai. Hillel, the grandfather of Gamaliel, held that tradition was superior to the Law. The school of Schammai despised traditionalists, especially when there teachings clashed with the writings of Moses. The religious school of Gamaliel (Hillel) was chiefly oral and usually had a prejudice against any book but Scripture. They used a system of Scriptural exegesis, and Josephus in his writings expressed the wish to have such a power of exegesis. When school was in session, learned men met and discussed scriptures, gave various interpretations, suggested illustrations, and quoted precedents. The students were encouraged to question, doubt, even contradict. -- When Paul became a Christian, his very thorough education was enormously helpful. He was able to assimilate Christian doctrines rapidly and relate them accurately to the Scripture teaching he had received. From his education, both from Gamaliel and in the desert from the Lord Jesus Christ, Paul developed a divine viewpoint attitude toward human history. Paul knew that the existence of God can easily be perceived by anyone, that man can become aware of God, but that many men's deliberate sin halted this good beginning by immoral activities which accompanied their idolatry. Therefore, Paul had an intense hatred of idolatry of any kind. Paul's teaching shows that the only reality is God. Idolatry distorts man's conception of the world and external nature. Idolatry is the enemy of mankind. Paul knew the law of growth of human nature. As a Roman, Tarsian, Hebrew, and culturally Greek, he knew of the many distortions of the life of his society. As a nation becomes unhealthy, development is halted. Societies errors as to the nature of God and the true relation of God to man prevented nations from getting rid of their besetting evil. The books of Acts is the chief authoritative record for the ministries of Paul and the other apostles. For a brief outline of Paul's ministry, see the Chronological Table of Paul's Ministry. The most thorough, accurate, and interesting secular work on Paul is The Life and Epistles of St. Paul, by Conybeare and Howson.



  • 1. 0 A.D. to 312 A.D. - Birth of Jesus and the early Church Age
  • Christian Church History Study

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The Pierre Statement on Biblical Doctrines by confessing Christians - As the Christian Church there are areas where we can all Agree to Agree! (PDF)

Over the years the Christian Church has virtually been defined by its vast ability to disagree. In fact the quote "let's agree to disagree" can almost be the new banner of Christianity. Some people readily point out and wonder if there really is a Christian truth because the Church itself agrees on very few Christian tenants. But this is not really an accurate reflection because the Church does agree on many things and is united on many beliefs. This is a discussion list where we as Christians can "Agree to Agree" and then the next time someone says "the Church doesn't even agree" well here are some areas of agreement. - These topics are starting beyond the already given basics of Christianity in that Jesus Christ is God born of the Virgin Mary, Himself a Godly encounter physically among humans yet remaining consistent with the Triune nature of God the Father, the Son Jesus Christ and the Holy Spirit. Jesus is Divine and without sin. He was rejected by mankind crucified and died. His death is the Full Payment for all of the sins of the world. His resurrection is of Everlasting Life and provided to those who personally receive Him as God and their Savior. Jesus is the rightful and righteous Ruler of the world and He will physically return to righteously reign, rule and judge His creation that we call the universe. -- "1 Corinthians 15:1-4 Moreover, brethren, I declare unto you the gospel which I preached unto you, which also ye have received, and wherein ye stand; By which also ye are saved, if ye keep in memory what I preached unto you, unless ye have believed in vain. For I delivered unto you first of all that which I also received, how that Christ died for our sins according to the scriptures; And that He was buried, and that He rose again the third day according to the scriptures" - All the best, God bless everyone ~ David Anson Brown




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Let God Lead Us: A Return to Holiness -- The Biblical Basis for the Doctrine of Holiness by Dr. Kenneth Geiger

Introduction: This study is based upon the premise, and the writer holds the view, that both the Old and New Testaments constitute the divinely inspired Word of God, inerrant in the originals, and the final authority for life and truth. This is the official position of the National Holiness Association and, quite uniformly, the view of Wesleyan-Arminians everywhere. Therefore, the Bible provides an authoritarian basis for the doctrine of holiness. Careful exegesis under the leadership of the Holy Spirit will not only communicate with the prophetic voice of "thus saith the Lord," so much needed in our day, but will contribute a dynamic force to the message of full salvation and deliverance from both the penalty and power of sin. ... From the very beginning God progressively revealed His holiness to man, as man was capable of understanding that holiness. The grandeur of the creation has given to men of all ages, notwithstanding the effects of the curse because of sin, a sense of awe (cf. Ps. 69). This is a step in developing the concept of the holiness of the Creator, and it accounts for the rise of the multiplied religious superstitions all over the world as man has sought peace with a force greater in power aud purity than himself. -- Before we examine a number of Scriptures which set forth the holiness of God, **let us be reminded that holiness is not essentially power as expressed in the creation and other works of God; it is essentially a moral purity. Wiley states, "Holiness as it relates to the Father, expresses the perfection of moral excellence which in Him exists unoriginated and underived." It is not only a principle of divine action, but it is incumbent upon His creatures. It is important that we take careful note of the Bible teaching which relates the holiness of God to man. Again Wiley says, "It is evident that holiness is not only the inward character of God as perfect goodness but consistency with this character as a standard for His own activity; and further, it is a requirement for His morally responsible creatures." ... The Epistle to the Ephesians has become a favorite as a basis for preaching holiness. ... This New Testament book also deals with the growth aspect of the holy life in chapter 4. After presenting the church universal, the Apostle [Paul] identifies the various functions of apostles, prophets, evangelists, pastors and teachers for the "perfecting [completing - achieving] of the saints." This process is to continue until "we all come in the unity of the faith, and of the knowledge of the Son of God, unto a perfect [complete] man, unto the measure of the stature of the fulness of Jesus Christ." While absolute perfection cannot be realized in this life, **we can achieve Christian maturity: "That henceforth we be no more children" (4:14). This process will culminate in the glorification of the church, as described in chapter 5, verses 25-27: "Husbands, love your wives, even as Christ also loved the church, and gave Himself for it; that He might sanctify and cleanse it by the washing of water by the Word, that He might present it to Himself a glorious church, not having spot, or wrinkle, or any such thing; but that it should be holy and without blemish." The present tense in the book of Ephesians is impressive and significant. They were at the time of Paul's writing, saints (1:1). Now, we as they, are in Christ (2:13), and none are no more strangers and foreigners, but fellow-citizens with the saints (2:19). **Now we have access to God (2:18). Now the power of God works in us. "Now unto Him that is able to do exceedingly above all that we ask or think, according to the power that worketh in us" (3:20). It was a happy day in my life, after a period of confusion resulting from oft repeated cliches, and so much theoretical preaching which was not Bible based, that the Bible itself began to speak to me and its total message was fully redemptive. ***The atoning work of Jesus Christ was adequate for my deepest need, for both time and eternity. This truth is so vast and so profound that we will always be reaching out to comprehend and appropriate it. This study has touched only the surface. Nothing has been said about the typology of holiness. Such works as A. B. Simpson's two volumes, The Holy Spirit, are especially valuable to such a study. I am convinced that the Bible is relevant, and that there is a Biblical basis for the doctrine of holiness.




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Find Your SFF Tribe On Mastodon

How to find the people who are talking about speculative fiction and books on the Fediverse.




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Hanfplantagen: Haftstrafen für Pensionisten-Trio

Am Salzburger Landesgericht wurden am Montag drei Pensionisten und eine 48-jährige Frau wegen der Herstellung und des Verkaufs von Suchtgift verurteilt. Sie sollen zwei Hanfplantagen betrieben haben. Die zwei Hauptangeklagten bekamen je dreieinhalb Jahre Haft, ein dritter ein Jahr.


orf.at




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Volontariat im Bereich Filmverleih und -vertrieb

Unser Hamburger Filmverleih Little Dream Pictures bringt sowohl unterhaltsame Familienfilme als auch Arthouse-Produktionen in die deutschsprachigen Kinos und übernimmt deren Vertrieb und Vermarktung. Unser Repertoire erstreckt sich dabei von Dokumentarfilmen über politische Dramen bis hin zu Animationsfilmen für alle Altersgruppen. Seit unserer Gründung 2016 sind wir kontinuierlich gewachsen und haben es uns zum Ziel gemacht all unseren Projekten eine optimale Betreuung und Vermarktung zu bieten. Wir sind… | Little Dream Pictures GmbH – Hamburg




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DAQ Software offers 4 triggers for data logging.

Windmill v6 modular data acquisition and control software suite collects data from sensors and equipment such as thermocouples, pressure transducers, flow meters, USB and Modbus devices. It runs under Windows 98 and later, and all programs are ready-to-run with no programming required. Software provides 4 choices of how to trigger data logging: when equipment sends new data, when readings cross alarm threshold, on pressing space bar on keyboard, or upon pressing software Start button.