José Camilo Manzur, director ejecutivo de Asocodis, habló sobre como el Gobierno de turno maneja la crisis energética en Colombia

Jorge Enrique Abello, actor, habló sobre cuáles son las fases del duelo y por qué razones hay que conocer el libro "La despedida"

Javier Suárez, presidente de Davivienda, habló en 6AM sobre cuáles son las nuevas oportunidades que ofrece ese banco para la economía del país 

Nathalia Calero, colombiana en Valencia, habló sobre cómo ha avanzado la crisis en esa ciudad de España tras los desastres en los últimos días 

Daniel Baliz, colombiano en Valencia, habló en 6AM sobre cómo avanzan los días de los habitantes de esta región tras la emergencia por las inundaciones

Michael Smith, political science professor at Emporia State, shares his perceptions of the results of the November 5 election with University of Kansas professor Karl Brooks and Radio Active Magazine […]

The post A Deep Dive into the 2024 Elections with Kansas politics specialist Prof. Michael Smith appeared first on KKFI.

Donald Trump Elected As The Next U.S. President The election of Donald Trump as our next president exposed a truth about where we the people are at. Because there could […]

The post Donald Trump Elected As The Next U.S. President and A Democratic Party Disaster appeared first on KKFI.

Wednesday MidDay Medley Produced and Hosted by Mark Manning Wednesday, November 13, 2024 Brock Wilbur & Nick Spacek of The Pitch + Damron Russel Armstrong of The Black Repertory Theatre […]

The post WMM presents Brock Wilbur & Nick Spacek of The Pitch + Damron Russel Armstrong of The Black Repertory Theatre of Kansas City appeared first on KKFI.

Después de una larga investigación, el documentalista David Baute llega a una conclusión. “A estas alturas ya no podemos ir con muchos paños calientes”, dice. via Pocket

My uncles are all gone now. But there are many veterans here with us now, from many fields of battle, suffering the consequences and they don't have the support they need or haven't been connected to that help.

Courtland Sutton and the Broncos were still celebrating his 32-yard touchdown catch in the second quarter Sunday when the tremor preceding the earthquake rippled.

Antonio Pierce’s Las Vegas Raiders kept alive their hopes of reaching the AFC playoffs after defeating the Kansas City Chiefs 20-14 at GEHA Field at Arrowhead Stadium yesterday [December 25]. The victory further stakes Pierce’s claim to the permanent job in Las Vegas. Pierce – the son of Bermudian Cleo Burrows – was promoted from […]

This true crime docuseries examines the murder of Annie Mae Aquash - a Mi'kmaq woman from Nova Scotia, Canada, a mother of two daughters, a teacher, and a revolutionary who fought for Indigenous rights in the 1970s and whose death went unsolved for almost 30 years.

So Apple isn't fighting for diversity. They're doing exactly what they appear to be doing: they're trying to keep wages down and keep their workers compliant by importing labor from abroad.This isn't about diversity. It's about exploitation. It always is Continue reading →

1. All-time reaction to coaching ‘disaster’; Steph’s stunning clutch moment: NBA Wrap  Fox Sports
2. Bike rides and Balkan music: Klay Thompson is embracing a fresh start with the Mavericks  ESPN Australia
3. 10 unforgettable Klay Thompson moments with Warriors ahead of return  NBA.com
4. Dub Hub: Warriors players share ‘welcome back’ messages for Klay Thompson’s return  Golden State of Mind

Hunter Dickson led No. 1 Kansas to an impressive win over Michigan State, while Mark Pope aced his first big test as Kentucky's head coach.

Photo by NASA Natural disasters don’t just ravage landscapes—they also expose and deepen systemic inequalities. Recent hurricanes, Milton and Helene, tore through Florida, Georgia, and the Carolinas, destroying homes, businesses, and the lives built across generations. While governments rush to repair infrastructure and restore housing, they often overlook the people most impacted in the long term—especially […]

The post Natural Disasters Aren’t Gender Neutral – Hurricanes Milton and Helene Prove It appeared first on Feminist Majority Foundation.

Hisashi Kobayashi, whose steady leadership as dean guided Princeton's School of Engineering and Applied Science through a rapid expansion of programs and facilities in the late 1980s and early 1990s, died on March 9. He was 84.

A morte por esfaqueamento de uma jovem húngara, assassinada logo após dar à luz, intriga a polícia há 15 anos.

A public hearing is set to examine the events surrounding the catastrophic failure of Oceangate’s submersible.

A selection of the week's best photos from across the African continent and beyond.

This is how disgusting Democrats are… the man who tried to murder Ronald Reagan in 1981 is now telling Democrats to stop asking him to assassinate Donald Trump. If you are a Democrat, you can’t be hated enough. Hinkley had to tell Democrats to stop with their negativity on social media, WAVY-TV reported. “I’m a […]

The post Would-Be Reagan Assassin John Hinkley Tells Leftists to Stop Asking Him to Murder Donald Trump appeared first on The Lid.

United Nations Secretary-General Antonio Guterres told world leaders at the COP29 summit on Tuesday to "pay up" to prevent climate-led humanitarian disasters, and said time was running out to limit a destructive rise in global tempera

velocityconf: New #velocityconf speaker interview w/ @sascha_d http://t.co/zg4tzDzIlH Config Management: It's Not About the Tool

News24 brings you the top stories of the day, summarised into neat little packages. Read through quickly or listen to the articles via our customised text-to-speech feature.

Scientific tests confirm rivers and dams have been poisoned by the raw sewage dumped by the municipality in the Bloubankspruit and Crocodile Rivers, killing aquatic life and destroying businesses and livelihoods.

In his latest Rucking with Rob newsletter, Rob Houwing argues that for England to have any hopes of beating the Springboks, they'll have to be on the ball in the final stages.

Independent Thinking: Humanitarian disaster in Syria and Turkey Audio NCapeling 16 February 2023

Episode 15 of our weekly podcast examines the far-reaching consequences of the earthquakes which struck Turkey and Syria on the region’s fragile geopolitics.

With thousands killed and international aid flooding in, what hope is there for the many thousands of people in Syria and Turkey caught between the groups and governments involved in conflict for more than a decade.

The panel aslo discusses the political impact within Turkey, as fears grow that President Recep Tyap Erdogan may postpone the upcoming election amid outcries over corruption and the devastating loss of life.

Joining Bronwen this week is Lina Sinjab, Syrian filmmaker and BBC journalist covering the Middle East, Charles Lister, senior fellow and director of the Syria programme at the Middle East Institute, and Ziya Meral, senior associate fellow on Turkey at the Royal United Services Institute (RUSI).

About Independent Thinking

A weekly podcast hosted by Chatham House director Bronwen Maddox, in conversation with leading policymakers, journalists, and Chatham House experts providing insight on the latest international issues.

Centrioles are key eukaryotic organelles that are responsible for the formation of cilia and flagella, and for organizing the microtubule network and the mitotic spindle in animals. Centriole assembly requires oligomerization of the essential protein spindle assembly abnormal 6 (SAS-6), which forms a structural scaffold templating the organization of further organelle components. A dimerization interaction between SAS-6 N-terminal “head” domains was previously shown to be essential for protein oligomerization in vitro and for function in centriole assembly. Here, we developed a pharmacophore model allowing us to assemble a library of low-molecular-weight ligands predicted to bind the SAS-6 head domain and inhibit protein oligomerization. We demonstrate using NMR spectroscopy that a ligand from this family binds at the head domain dimerization site of algae, nematode, and human SAS-6 variants, but also that another ligand specifically recognizes human SAS-6. Atomistic molecular dynamics simulations starting from SAS-6 head domain crystallographic structures, including that of the human head domain which we now resolve, suggest that ligand specificity derives from favorable Van der Waals interactions with a hydrophobic cavity at the dimerization site.

When using the distinct count function in SAS Visual Analytics reports, you might find that a negative value is displayed instead of the actual distinct count: imgalt="distinct_count" src="{fusion_66562_1_disti

If you connect to a FTP/TLS server that is configured to use implicit FTP/TLS, FILENAME FTP/TLS might fail with the following error:

The bacterial enhancer-binding protein (bEBP) FlrC, controls motility and colonization of Vibrio cholerae by regulating the transcription of class-III flagellar genes in σ54-dependent manner. However, the mechanism by which FlrC regulates transcription is not fully elucidated. Although, most bEBPs require nucleotides to stimulate the oligomerization necessary for function, our previous study showed that the central domain of FlrC (FlrCC) forms heptamer in a nucleotide-independent manner. Furthermore, heptameric FlrCC binds ATP in “cis-mediated” style without any contribution from sensor I motif 285REDXXYR291 of the trans protomer. This atypical ATP binding raises the question of whether heptamerization of FlrC is solely required for transcription regulation, or if it is also critical for ATPase activity. ATPase assays and size exclusion chromatography of the trans-variants FlrCC-Y290A and FlrCC-R291A showed destabilization of heptameric assembly with concomitant abrogation of ATPase activity. Crystal structures showed that in the cis-variant FlrCC-R349A drastic shift of Walker A encroached ATP-binding site, whereas the site remained occupied by ADP in FlrCC-Y290A. We postulated that FlrCC heptamerizes through concentration-dependent cooperativity for maximal ATPase activity and upon heptamerization, packing of trans-acting Tyr290 against cis-acting Arg349 compels Arg349 to maintain proper conformation of Walker A. Finally, a Trp quenching study revealed binding of cyclic-di-GMP with FlrCC. Excess cyclic-di-GMP repressed ATPase activity of FlrCC through destabilization of heptameric assembly, especially at low concentration of protein. Systematic phylogenetic analysis allowed us to propose similar regulatory mechanisms for FlrCs of several Vibrio species and a set of monotrichous Gram-negative bacteria.

For data that is being loaded from a SAS Stored Process Server, an insertion process might fail to a MySQL database with a warning, as well as an error message that says "During insert: Incorrect datetime value…"

In SAS Customer Intelligence Studio, you might notice that the user interface becomes unresponsive, as shown below: imgalt="SAS Customer Intelligence Studio UI becomes unresponsive" src="{fusion_66537

In SAS Customer Intelligence Studio, you can choose to create a new calculated variable in the Edit Value dialog box when you populate a treatment custom detail. Following creation of the new calculated

In SAS Customer Intelligence Studio, you might notice that you cannot clear warnings for decision campaign nodes by selecting either the Clear Warnings  option or the Clear All Warnin

In SAS Customer Intelligence Studio, the following error is displayed when you update a new Link  node in a diagram:   imgalt="Link: MAIQService:executeFastPath:" src="{fusion_665

You encounter this issue when the table metadata matches the data source. In this scenario, no metadata update is required.

In SAS Business Rules Manager 3.3, the initial loading of a rule set and a rule flow takes significantly longer than it does in release 3.2. When this problem happens, long time gaps are evident in the local

If you have configured more than one SAS Application Server, then SAS Visual Data Builder might unexpectedly use the wrong application server when you preview or schedule queries. This problem occurs even though you h

You might see the following error messages: "ERROR: Connection failed. Server returned: SAS Logon Manager authentication failed: Access denied." and "ERROR: Unable to connect to Cloud Analytic Services host-name on port 5570. Veri

Editing and/or saving an action column can take up to a minute to display a window. There are no workarounds identified at this time.

If the response variable is in the CLASS statement variable list before the class variables that also appear in the MODEL statement, and an OM-data-set is used, least squares means results for several of the statistical procedures are incorrect.

You might receive a Segmentation Violation when opening a database table in SAS. The SAS Log contains the error and traceback:

In SAS Life Science Analytics Framework 4.6, group membership removal fails with an exception if a user is set as assignee, a candidate, or a notification recipient in a user task for a Process Flow . The Process

An error might occur when you use the SAS 9 BULKLOAD= and BULKEXTRACT= options load data to or extract data from HP Neoview on the HP Itanium platform. The problem occurs because Hewlett-Packard changed the name of one of

In SAS Merchandise Financial Planning, custom time frame-based data versions do not aggregate correctly when referenced in worksheets with standard hierarchy levels. The data does not aggregate correctly from l