obs Cap Of 175 Recreational Lobster Diver Licenses By bernews.com Published On :: Mon, 05 Aug 2024 15:44:17 +0000 The Ministry of Home Affairs advises the public that the “number of recreational lobster diver licenses will be capped at 175 for the upcoming 2024-2025 spiny lobster season, which begins on 1st September.” A Government spokesperson said, “This limit remains unchanged from last season. Licenses will be issued on a first-come, first-served basis starting Wednesday, […] Full Article All Environment News #BermudaGovernment #Fishing #Lobster
obs Sumptuous Lobster Rolls For The Big Game Meal By www.spiceplace.com Published On :: Sun, 22 Jan 2017 12:00:22 +0000 Somehow Buffalo Wings became the staple meal for the Big Game. And while lobster seems like an expensive, once in a while special treat, the price has come down lately so the price per serving of this recipe is quite reasonable. This is a simple and yummy meal that’s ready in minutes. These are best … Full Article Cooking Ideas Main Dishes Maine Lobster Rolls
obs Big Tech opposes temporary blocking of H-1B guest worker visas because it wants to give your childrens’ jobs to cheap foreign labor By www.cpa-connecticut.com Published On :: Thu, 02 Jul 2020 14:56:08 +0000 So Apple isn't fighting for diversity. They're doing exactly what they appear to be doing: they're trying to keep wages down and keep their workers compliant by importing labor from abroad.This isn't about diversity. It's about exploitation. It always is Continue reading → Full Article Accountants CPA Hartford Articles Amazon Apple Apple's CEO Big Tech Big Tech opposes temporary blocking of H-1B guest worker visas because it wants to give your childrens' jobs to cheap foreign labor blocking guest worker visas cheap foreign labor diversity Donald Trump exploitation Google H-1B guest worker visas http://cpa-connecticut.com/barefootaccountant/big-tech-opposes-temporary-blocking-of-h-1b-guest-worker-visas-because-it-wants-to-give-your-childrens-jobs-to-cheap-foreign-labor/ India Silicon Valley STEM Tim Cook Tucker Carlson Tonight July 1 2020
obs Board Game Review: Obsessed with Obsession By www.thatswhatjennisaid.com Published On :: Wed, 01 Jun 2022 15:20:00 +0000 I'm completely obsessed with Obsession! I received a review copy of the updated second edition along with all the expansions (Wessex, Useful Man, Upstairs Downstairs) and from the moment I took everything out of the boxes, my excitement was over the top. Actually, that's not even the half of it - I remember I was already quite excited before the game even arrived. I'd wanted to get my hands on a copy as soon as I learned there was a game that brought the lifestyle that we all fell in love with watching Downton Abbey to the gaming table. Back in 2021, I was having a great time at the Dice Tower Summer Retreat and a new friend Bonnie sang the praises of Obsession. She had seen me eyeing the box on the shelf and gave me a summary of the game mechanics as she owned the first edition. She explained that the theme is centered on running an estate in Derbyshire and competing against others to have the best home, reputation, gentry guests, etc. Based on her enthusiasm and description of the game, my husband and I sat down to play it that afternoon. I ruthlessly squashed him 96 to 78 in our first game and I was hooked. Back at home, months later, with the second edition and the expansions in front of me, my first task was organizing everything into one box. The publisher had included all of the expansions to ensure I had the complete experience, but as far as I could tell, some of the materials sent were duplicate cards or tiles. And that was true, even after carefully reviewing and incorporating the items that seemed to be dupes but turned out to be replacements for base game components with subtle changes. I think this happened because the Upstairs Downstairs expansion comes with materials to update the 1st edition of the base game, but those materials are already included in the second edition of the base game that I received, resulting in duplicates. I mention it in case you order the newer edition and all the expansions and find yourself wondering what’s going on with extra items you find. I just set them aside in my spare parts box. Anyway, let’s start by cataloging the components in the base game, shall we? The 2nd edition comes with: Supply Board Used to hold the Builder’s Market of improvement tiles available for purchase, as well as the guests, servants and objective cards that may be acquired as the game unfolds. Round Track Board Keeps the progress of the game flow through each round and season (a season is 3 rounds plus a special round called a courtship). There are 16 or 20 rounds to a game, depending on whether you play a standard or extended game. The Round Track also holds the theme cards, the victory point cards, and the two very special guests every estate is dying to get an audience with – Mr. Charles Fairchild and his sister Elizabeth Fairchild. Player components (given to each player) Family board to organize and process their estate’s reputation, servants, improvement tiles, and hosted events Starting estate tiles (improvement tiles) Set of basic servants Small hand of family guest cards + 2 casual guest cards designated as starter guests Reputation wheel counters Reminder tiles Player aids Any addl bonus guests, rooms, money, or servants granted by the family’s unique profile Other components Money (pounds) Scorepad Improvement tile bag Components for solitaire play Rulebook and Glossary These components are all well made and under normal use should last a long time and wear well. The rulebook is well written and the glossary makes it evident this was a passion project for the designer, as it goes into great detail regarding the historical significance of the various tiles and guests. Absolutely love it! Both the font and the artwork help to carry the theme across the components, which was a great point of detail. Gameplay is relatively straightforward. Across their turns, players are responsible for managing estate tiles, guests, and servants while seeking to conform to courtship themes, improve their reputations, and complete objectives. At the end of the game, the player with the most victory points is the winner. Managing Estate Tiles During the game, each player will be responsible for managing the improvement tiles on their estate. Initially, each player only has a handful of starter tiles, but over time their estate will expand to include additional tiles purchased from the supply board. Each tile confers one or more benefits (called favours) when played, in the form of money, the ability to draw additional guests or dismiss guests one already has, the ability to hire additional servants, increased reputation, and end game victory points. Improvement tiles are flipped over after first use, typically revealing different favours on the backside. Most tiles remain on their backside after initial use, but some improvement tiles are designed to be flipped after each use. Note: each improvement tile has requirements as to which type of guest[s] and servant[s] are required to host an event with that tile so it’s essential that players approach estate tile management in a coordinated fashion with guest and servant management. Managing Guests In addition to their estate tiles, players must also manage a hand of guest cards (which are discarded individually after use to a personal discard pile and recalled en masse when passing). At the beginning of the game, the hand is comprised of family members and casual guests dealt directly to players, but as with the player estates, as the game continues into successive rounds, it will expand. Additional cards added to the hand will be drawn from the casual and prestige guests on the supply board. Just as improvement tiles provide favours, so do guests. Prestige guests give better favours and are generally worth more end game victory points. Some guests, based on their thematic description, have destructive favours that you have to watch out for. For example, a male guest labeled a cad might lower your reputation should you invite him to an event and offer negative victory points if you find him in your hand at game’s end. Adding a bit of complexity to the puzzle, guests may often have requirements for servants printed on their card; this is in addition to any servant[s] specified on improvement tiles used to host events. Managing Servants With improvement tiles to host prestigious events and guests to attend those events, of course servants will be needed to keep things proper in high society. After all, the guests aren’t going to serve themselves! Not to worry; players begin with a few starting servants, and will hire on more help as they wish to during the course of the game. In this way, staff management becomes the third leg of family affairs. Servant management can be especially tricky. This is because you typically cannot hire additional servants without having one of your most useful servants available (the butler). Additionally, to be kind to our staff and not overwork them, after a servant has been used during a turn, it’s not available again until two turns later (although a player can spend reputation if they are desperate and force a servant back to work early). It’s very easy for a player to back themselves into a corner with plenty of improvement tiles and guests ready to go and a shortage of servants to make the event happen. Courtship Themes At the beginning of each season, an event theme is drawn, revealing the improvement tile category that will be evaluated at the end of that season, during the courtship round. During evaluation, the player with the most victory points showing on the tiles in their estate matching the theme will be awarded a victory point card and their choice of the Fairchild guest cards. The victory point cards offer a player the choice of a useful one time in-game benefit or a chunk of end game victory points. And while the player must give the Fairchild guest back at the end of the next season, having them in hand during the next season to take advantage of their favours is very beneficial. Hence, tailoring improvement tile purchases and tiles selected for hosting (to flip them and reveal their higher VP side) to the theme each season is an essential tenant of good strategy and game winning players tend to correlate with VP card awardees. Reputation You cannot win this game without paying attention to reputation. Every improvement tile and guest card has a minimum prestige rating printed on them (or implied as in the case with family and the Fairchilds) which represent the minimum reputation required to use them for a hosted event. If you don’t improve your reputation as the game plays out, you’ll eventually be shut out of using the tiles and guests that have the greatest impact on final scoring. Additionally, a player’s reputation level at game end directly confers victory points, ranging from 1 point (for having a reputation level of 1) to 45 points (for having the maximum reputation level in an extended game). Finding ways to steadily increase reputation through favours found on improvement tiles and guest cards is very important. In every game I’ve played, the winner was among those with the highest reputations at game’s end. Objectives At the beginning of the game, all players are dealt a number of objective cards. These are end game goals, that if accomplished, reward victory points. They may be variable, such as x VP per servant on staff, or fixed amount, such as 16 VP for a player if they have tiles x,y, and z in their estate. While objectives are a great source of victory points and should not be entirely disregarded, I have generally found that the winners in our games are not the players who attain the most VPs from objectives. For example, in our most recent game, my friend Brian won a 5 player game with a total score of 221 (next closest player had only 189) and yet he brought in 28 of those points from objective cards while I had 38 points from objectives and two of the other players also had higher VP totals from their objectives than Brian. Player Turns On a player’s turn, they begin by rotating their servants a step toward active service. If they’re currently resting in the servant’s quarters they move to active service and if they were in the expended service area they move toward the servant’s quarters. Next, the player observes any round events (for example, some rounds designated as village fairs provide income and some tiles provide favours at the beginning of each round). After that’s completed, the player decides which tile they’d like to use to host an event, moves it to the active event box on their player board, and decides which guest[s] (of those that meet the requirements) will attend the event. To be eligible, the guest[s] must be in the player’s hand and not their discard pile. This is the point where they most also provide the required servants – placing those required by the tile on the tile and those required by the guest[s] on the guest[s] card. To be eligible, the servant must be in the available service area of the player’s board. Once servants have been placed, it’s time to collect favours from the tile and the guests (gathering or giving up money, reputation, additional guests, and additional servants as indicated). As a final step in the turn, a player may buy an improvement tile from the market. The market is setup with tiles that have been drawn randomly from the tile bag and placed in market slots with prices listed above. When a tile is purchased, tiles in higher priced market slots are shifted over to fill the gap and a new tile is drawn from the bag and placed in the most expensive market slot. Normally, each player is limited to buying only one tile during a round, except during a special round that represents the Builder’s Holiday that allows them to buy as many tiles as they can afford and wish to purchase. Once a player finishes their turn, play passes to the next player. Once every player has had a turn during a round, the round marker is moved to the next round and the process begins again. During the courtship round of each season, no player actions are taken; this round is used exclusively to evaluate player performance against courtship themes. So that’s the nuts and bolts of the base game. It’s on point and the gameplay is both a challenging puzzle and entertaining adventure at the same time. Highly recommend! I can’t find a single fault in the game. Not a one. I could probably play Obsession dozens and dozens of times as presented in the base game and still be enthusiastic about it, just like my friend Bonnie was. But I was lucky enough to have all the expansions in front of me from the get go, so of course I started incorporating them as well, in the second or third play of the game. Let’s go over those now. Wessex Expansion Wessex adds a fifth family to the game, giving players an additional choice when selecting starting families. Dan provides a great deal of narrative backstory for the new family in the expansion insert booklet and I just love that. Again, great attention to detail, and it’s really appreciated by players like myself who care about theme and want to understand the backstory of who we are playing in a game and what our motivations are all about. This expansion also includes two new improvement tiles and an extended mode solitaire option. You’re going to want to pick up this expansion for the variability it provides. I have a personal goal to win the game as each family, so this adds to my challenge. Upstairs Downstairs Expansion This is a major expansion that adds complexity, variability, and extra joy to the base game through a lot of new and updated components. There are four new servant types, each of which has a variety of effects when integrated into the game. Very clever and all seamlessly thematically appropriate. There are dozens of new guests (including very unique promotional guests), objectives, and improvement tiles. There’s a new set of cards called milestones that offer in-game shared objectives that award victory points to the players who complete them first. There’s even a new round track board to facilitate a new game variant. For those who aren’t madly in love with the cute little mini sized VP and Objective cards included in the base game, this expansion provides a duplicate copy of these decks in a larger format. It’s actually a little debate in our group as to which set of decks to use every time we sit down to play as I really like the little cards but some of my friends appreciate the easier-to-read larger cards. As an added bonus, the expansion also allows the game to scale to 5 or 6 players (by providing an additional family/extra improvement tiles/extra basic servants). You’re going to want to pick up this expansion because it’s nothing short of amazing. It's a can’t live without. Useful Box Expansion This expansion is mostly a correctional tool, updating tiles from the base game (both the 1st and 2nd printings) that have errors as well as problematic tiles from the Upstairs Downstairs expansion. There are also a few new tiles and some components to expand solitaire variants. While this expansion was necessary for me, I would expect the entirety of the corrections and new tiles to be folded into the next printings of the respective games (base or U/D expansions) and likely unnecessary for future buyers. Just make sure to check your edition to determine if this expansions provides value for you or not before you spring for it. Etsy Stickers I might be on the dark side of the publisher for recommending these (as they appear to be unlicensed) but I found these adorable meeple stickers on Etsy (https://www.etsy.com/listing/1008836394/obsession-meeples-upgrade-kit-free) that really took the servant components over the top. Highly recommend them. I just want to add a final note about theme. Obsession is so perfectly themed, that it lends itself to glorious costuming around the game table in historical period appropriate attire. If you’re not willing to take it that far, at least consider hosting a formal tea with gourmet sandwiches and delicate sweets for your friends who come to play the game. It really elevates the whole experience. -------------------------------------------------- Publisher: Kayenta Games Players: 1-6 (We played with 2,3,4,and 5) Actual Playing Time (vs the guideline on the box): About 3 hours per game Game type: worker placement, hand management, tile placement games Rating: Jenni’s rating scale: OUI: I would play this game again; this game is ok. I probably would not buy this game myself but I would play it with those who own it and if someone gave it to me I would keep it. OUI OUI: I would play this game again; this game is good. I would buy this game. OUI OUI OUI: I LOVE THIS GAME. I MUST HAVE THIS GAME. NON: I would not play this game again. I would return this game or give it away if it was given to me. Full Article board game expansions board game reviews hand management games Kayenta Games tile placement games worker placement games
obs Bobsleighers want tracks covered By www.bbc.co.uk Published On :: Sat, 21 Jan 2012 09:08:15 GMT Great Britain's bobsleigh team call for all sliding tracks to be covered after heavy snowfall at the Winter Youth Olympics in Austria. Full Article Winter Sports
obs i swear to god lobsters By www.marriedtothesea.com Published On :: Wed, 07 Feb 2024 04:00:00 EST Today on Married To The Sea: i swear to god lobstersThis RSS feed is brought to you by Drew and Natalie's podcast Garbage Brain University. Our new series Everything Is Real explores the world of cryptids, aliens, quantum physics, the occult, and more. If you use this RSS feed, please consider supporting us by becoming a patron. Patronage includes membership to our private Discord server and other bonus material non-patrons never see! Full Article autogen_comic
obs 5 Everyday Workers Who Turned Into Action Heroes at Their Jobs By www.cracked.com Published On :: Mon, 11 Nov 2024 05:00:00 -0800 By Ryan Menezes Published: November 11th, 2024 Full Article
obs Rare Natural Phenomenon Observed in Saint Petersburg By englishrussia.com Published On :: Sat, 02 Apr 2022 05:47:05 +0000 The post Rare Natural Phenomenon Observed in Saint Petersburg appeared first on English Russia. Full Article Photos Russian Nature saint-petersburg
obs Jo Dunkley, Suzanne Staggs and colleagues awarded $53M to upgrade prominent observatory By www.princeton.edu Published On :: Thu, 18 May 2023 14:55:02 -0400 The National Science Foundation has awarded a $52.66 million grant to fund a major infrastructure upgrade to the Simons Observatory in the Atacama Desert of Chile. Upgrades are expected to take about five years; the resulting facility will be known as the Advanced Simons Observatory (ASO). Full Article
obs Veterans Day observance to be held at the Princeton University Chapel By www.princeton.edu Published On :: Fri, 08 Nov 2024 10:59:36 -0500 The 9 a.m. service on Monday, Nov. 11, will also be livestreamed. Full Article
obs Trump lining up Marco Rubio and Kristi Noem for top jobs By www.bbc.com Published On :: Wed, 13 Nov 2024 02:11:08 GMT Trump could name Rubio as his secretary of state and Noem as his homeland security secretary, US media say. Full Article
obs Gold, prices, and jobs: What's at stake in Ghana's elections? By www.bbc.com Published On :: Tue, 12 Nov 2024 00:36:02 GMT In an echo of the US, the current vice-president is up against an ex-president in the 7 December vote. Full Article
obs Trump taps Marco Rubio & Michael Waltz, known to be pro-India and tough on China, for top jobs - The Indian Express By news.google.com Published On :: Tue, 12 Nov 2024 22:50:38 GMT Trump taps Marco Rubio & Michael Waltz, known to be pro-India and tough on China, for top jobs The Indian ExpressDonald Trump Sets 'Existential' Battle Against China With Cabinet Picks NDTVTrump's NSA pick Mike Waltz's pro-India stand in 5 quotes FirstpostTrump's incoming NSA Mike Waltz wants US to dance cheek-to-check with India The Times of IndiaWho is Mike Waltz, Donald Trump’s pick for national security adviser? The Hindu Full Article
obs Instant Reaction: Jobs, September 6, 2024 By www.nar.realtor Published On :: Fri, 06 Sep 2024 13:27:31 +0000 Instant Reaction: Jobs, September 6, 2024 The softening job figures suggest that the Federal Reserve will cut interest rates in mid-September. By: Lawrence Yun Full Article
obs Commentary: Creating Jobs and Changing Lives – The Return of American Manufacturing By deneenborelli.com Published On :: Tue, 17 Sep 2024 14:33:22 +0000 Commentary by Maggie Miller was originally published by RealClearFlorida and RealClearWire In the heart of Riviera Beach, Florida, a company called K12 Print is redefining what it means to do business in America. This isn’t just about profits and productivity for John DiDonato, the CEO and founder. While financial success is part of the equation, … Full Article Commentaries News
obs Analysis of {beta}-lactone formation by clinically observed carbapenemases informs on a novel antibiotic resistance mechanism [Enzymology] By www.jbc.org Published On :: 2020-12-04T00:06:05-08:00 An important mechanism of resistance to β-lactam antibiotics is via their β-lactamase–catalyzed hydrolysis. Recent work has shown that, in addition to the established hydrolysis products, the reaction of the class D nucleophilic serine β-lactamases (SBLs) with carbapenems also produces β-lactones. We report studies on the factors determining β-lactone formation by class D SBLs. We show that variations in hydrophobic residues at the active site of class D SBLs (i.e. Trp105, Val120, and Leu158, using OXA-48 numbering) impact on the relative levels of β-lactones and hydrolysis products formed. Some variants, i.e. the OXA-48 V120L and OXA-23 V128L variants, catalyze increased β-lactone formation compared with the WT enzymes. The results of kinetic and product studies reveal that variations of residues other than those directly involved in catalysis, including those arising from clinically observed mutations, can alter the reaction outcome of class D SBL catalysis. NMR studies show that some class D SBL variants catalyze formation of β-lactones from all clinically relevant carbapenems regardless of the presence or absence of a 1β-methyl substituent. Analysis of reported crystal structures for carbapenem-derived acyl-enzyme complexes reveals preferred conformations for hydrolysis and β-lactone formation. The observation of increased β-lactone formation by class D SBL variants, including the clinically observed carbapenemase OXA-48 V120L, supports the proposal that class D SBL-catalyzed rearrangement of β-lactams to β-lactones is important as a resistance mechanism. Full Article
obs Cell cholesterol efflux: integration of old and new observations provides new insights By www.jlr.org Published On :: 1999-05-01 George H. RothblatMay 1, 1999; 40:781-796Reviews Full Article
obs Regularity of capillarity droplets with obstacle By www.ams.org Published On :: Thu, 31 Oct 2024 16:22 EDT Guido De Philippis, Nicola Fusco and Massimiliano Morini Trans. Amer. Math. Soc. 377 (), 5787-5835. Abstract, references and article information Full Article
obs Asymptotic normality of estimators for all parameters in the Vasicek model by discrete observations By www.ams.org Published On :: Tue, 05 Nov 2024 14:10 EST Olha Prykhodko and Kostiantyn Ralchenko Theor. Probability and Math. Statist. 111 (), 123-135. Abstract, references and article information Full Article
obs Novel Proteomic Profiling of Epididymal Extracellular Vesicles in the Domestic Cat Reveals Proteins Related to Sequential Sperm Maturation with Differences Observed between Normospermic and Teratospermic Individuals By www.mcponline.org Published On :: 2020-12-01 Tricia RowlisonDec 1, 2020; 19:2090-2103Research Full Article
obs Problem Notes for SAS®9 - 66509: Several procedures in SAS/STAT Software and SAS/QC Software generate incorrect results when an OBSMARGINS= data set is used By Published On :: Fri, 28 Aug 2020 08:58:34 EST If the response variable is in the CLASS statement variable list before the class variables that also appear in the MODEL statement, and an OM-data-set is used, least squares means results for several of the statistical procedures are incorrect. Full Article STAT+SAS/STAT
obs Problem Notes for SAS®9 - 65782: The PLM procedure incorrectly issues the message "ERROR: No valid observation in the OM= data set" By Published On :: Wed, 26 Aug 2020 15:11:09 EST If the OBSMARGINS= or OM= option is specified in an LSMEANS, LSMESTIMATE, or SLICE statement and a user-defined format is applied to any of the effect variables in the OM-data-set , PROC PLM incorrectly stops proce Full Article STAT+SAS/STAT
obs Problem Notes for SAS®9 - 66505: The OBS= option does not generate a limit clause when you use SAS/ACCESS Interface to PostgreSQL to access a Yellowbrick database By Published On :: Wed, 26 Aug 2020 11:35:41 EST When you use SAS/ACCESS Interface to PostgreSQL to query a Yellowbrick database, the SAS OBS= option is not generating a limit clause on the query that is passed to the database. Click the Full Article POSTGRESOFR+SAS/ACCESS+Interface+to+Post
obs Novel Proteomic Profiling of Epididymal Extracellular Vesicles in the Domestic Cat Reveals Proteins Related to Sequential Sperm Maturation with Differences Observed between Normospermic and Teratospermic Individuals [Research] By www.mcponline.org Published On :: 2020-12-01T00:05:33-08:00 Extracellular vesicles (EVs) secreted by the epididymal epithelium transfer to spermatozoa key proteins that are essential in promoting motility and subsequent fertilization success. Using the domestic cat model, the objectives were to (1) characterize and compare protein content of EVs between segments of the epididymis, and (2) compare EV protein compositions between normo- and teratospermic individuals (producing >60% of abnormal spermatozoa). Epididymal EVs from adult cats were isolated and assessed via liquid chromatography tandem MS. Both male types shared 3008 proteins in total, with 98 and 20 EV proteins unique to normospermic and teratospermic males, respectively. Expression levels of several proteins changed between epididymal segments in both male types. Several proteins in both groups were related to sperm motility (e.g. hexokinase 1, adenylate kinase isoenzyme) and zona pellucida or oolemma binding (e.g. disintegrin and metalloproteinase domain proteins, zona binding proteins 1 and 2). Interestingly, seven cauda-derived EV proteins trended downward in teratospermic compared with normospermic males, which may relate to poor sperm quality. Collective results revealed, for the first time, EV proteins related to sequential sperm maturation with differences observed between normospermic and teratospermic individuals. Full Article
obs Endovascular treatment for acute ischaemic stroke in routine clinical practice: prospective, observational cohort study (MR CLEAN Registry) By www.bmj.com Published On :: Friday, March 9, 2018 - 14:16 Full Article
obs Clinical Factors That Influence Repeat 68Ga-PSMA-11 PET/CT Scan Positivity in Patients with Recurrent Prostate Cancer Under Observation After a Negative 68Ga-PSMA-11 PET/CT Scan: A Single-Center Retrospective Study By jnm.snmjournals.org Published On :: 2024-10-01T04:08:08-07:00 This analysis aimed to identify clinical factors associated with positivity on repeat 68Ga-PSMA-11 PET/CT after a negative scan in patients with recurrent prostate cancer (PCa) under observation. Methods: This single-center, retrospective analysis included patients who underwent at least 2 68Ga-PSMA-11 PET/CT scans (PET1 and PET2) at UCLA between October 2016 and June 2021 for recurrent PCa with negative PET1 and no PCa-related treatments between the 2 scans. Using Prostate Cancer Molecular Imaging Standardized Evaluation criteria to define negative and positive scans, the final cohort was divided into PET2-negative (PET2-Neg) and PET2-positive (PET2-Pos). The same PET1 was used twice in the more than 2 PET cases with inclusion criteria fulfilled. Patient characteristics and clinical parameters were compared between the 2 cohorts using Mann–Whitney U test and Fisher exact test. Areas under the curve (AUCs) of the receiver operating characteristic and the Youden index were computed to determine the discrimination ability of statistically significant factors and specific cut points that maximized sensitivity and specificity, respectively. Results: The final analysis included 83 sets of 2 PET/CT scans from 70 patients. Thirty-nine of 83 (47%) sets were PET2-Neg, and 44 of 83 (53%) sets were PET2-Pos. Prostate-specific antigen (PSA) increased from PET1 to PET2 for all 83 (100%) sets of scans. Median PSA at PET1 was 0.4 ng/mL (interquartile range, 0.2–1.0) and at PET2 was 1.6 ng/mL (interquartile range, 0.9–3.8). We found higher serum PSA at PET2 (median, 1.8 vs. 1.1 ng/mL; P = 0.015), absolute PSA difference (median, 1.4 vs. 0.7 ng/mL; P = 0.006), percentage of PSA change (median, +270.4% vs. +150.0%: P = 0.031), and median PSA velocity (0.044 vs. 0.017 ng/mL/wk, P = 0.002) and shorter PSA doubling time (DT; median, 5.1 vs. 8.3 mo; P = 0.006) in the PET2-Pos cohort than in the PET2-Neg cohort. Receiver operating characteristic curves showed cutoffs for PSA at PET2 of 4.80 ng/mL (sensitivity, 34%; specificity, 92%; AUC, 0.66), absolute PSA difference of 0.95 ng/mL (sensitivity, 62%; specificity, 71%; AUC, 0.68), percentage of PSA change of a positive 289.50% (sensitivity, 48%; specificity, 82%; AUC, 0.64), PSA velocity of 0.033 ng/mL/wk (sensitivity, 57%; specificity, 80%; AUC, 0.70), and PSA DT of 7.91 mo (sensitivity, 71%; specificity, 62%; AUC, 0.67). Conclusion: Patients with recurrent PCa under observation after a negative 68Ga-PSMA-11 PET/CT scan with markedly elevated serum PSA levels and shorter PSA DT are more likely to have positive findings on repeat 68Ga-PSMA-11 PET/CT. Full Article
obs Stellantis trimming 1,100 jobs at its Toledo Jeep Gladiator plant By www.upi.com Published On :: Wed, 06 Nov 2024 20:17:44 -0500 About 1,100 workers will be laid off indefinitely in January from the Jeep Gladiator plant in Toledo, Ohio, Stellantis officials announced Wednesday. Full Article
obs Nissan to cut 9,000 jobs, reduce capacity by 20% as it faces 'severe situation' By www.upi.com Published On :: Thu, 07 Nov 2024 09:31:42 -0500 As Nissan on Thursday reported a roughly half-billion- dollar revenue drop in 2024, the Japanese automaker said it will cut 9,000 jobs and reduce manufacturing capacity by 20%. Full Article
obs Empty desks: Coronavirus robs US classrooms of teachers By www.teachermagazine.org Published On :: 2020-11-18T23:15:37-05:00 Full Article Education
obs Here's What One State Is Doing to Prepare Students for the Jobs of the Future By blogs.edweek.org Published On :: Thu, 06 Jun 2019 00:00:00 +0000 Maryland may be a model for how states should approach educating students for the workforce of the future, according to a new policy brief. Full Article Maryland
obs Nevada school district may cut jobs amid online learning By www.edweek.org Published On :: Mon, 23 Nov 2020 00:00:00 +0000 Full Article Nevada
obs Nevada school district may cut jobs amid online learning By www.edweek.org Published On :: 2020-11-23T08:45:44-05:00 Full Article Education
obs Here's How Many Teaching Jobs Could Be Lost in Each State in a COVID-19 Recession By blogs.edweek.org Published On :: Thu, 30 Apr 2020 00:00:00 +0000 There could be an 8.4 percent reduction in the U.S. teaching corps, and some states could see reductions as large as 20 percent, according to a new analysis by the Learning Policy Institute. Full Article Hawaii
obs Betsy DeVos to Visit Manufacturer Where Hundreds of Teachers Work Second Jobs By blogs.edweek.org Published On :: Wed, 17 Jul 2019 00:00:00 +0000 U.S. Secretary of Education Betsy DeVos will hold a workforce event at a South Carolina drug manufacturer that employs hundreds of cash-strapped teachers in second jobs. Full Article South_Carolina
obs Teachers Wanted: S.C. Company Hires Cash-Strapped Educators for Warehouse Jobs By blogs.edweek.org Published On :: Fri, 03 May 2019 00:00:00 +0000 Nephron Pharmaceuticals, a drug manufacturing company in West Columbia, S.C., recently hired 650 current and retired teachers through a new program designed to provide educators with additional income. Full Article South_Carolina
obs First Observance of the International Tea Day By www.fao.org Published On :: Thu, 21 May 2020 00:00:00 GMT Today we celebrate the cultural heritage, health benefits and economic importance of tea. Full Article
obs Global Accelerator on Jobs and Social Protection for Just Transitions: Investing in food and agriculture to achieve the SDGs By www.fao.org Published On :: Wed, 24 Jul 2024 00:00:00 GMT Social protection and decent jobs are cornerstones of agrifood systems transformation, but they require strong political commitment Full Article
obs Ouija Board: The Mysterious Origins of a Cultural Obsession By www.smithsonianmag.com Published On :: Thu, 31 Oct 2024 00:00:00 -0000 The Ouija board might seem like a simple game that sparks spooky childhood memories, but have you ever pondered its mysterious history? Even more importantly, does it actually…work? Uncover the fascinating truth behind the game and its unusual origins. ___ A little more information: In the late 19th century, Americans were captivated by Spiritualism, the belief that the dead could communicate with the living. Charles Kennard saw the commercial potential in this trend, leading to the creation of the Ouija board. Yet, the backstory behind its invention, its rules, and even its name are all wrapped up in uncertainty. One thing is certain: the more turbulent the times, the more popular the game became – particularly during World War II and the social upheaval of the late 1960s. Ultimately, the allure of the Ouija board lies in its ability to tap into human imagination and curiosity. Whether regarded as a nostalgic artifact or a mystical tool, the Ouija board is here to stay. #OuijaBoard #Ouija #history #Smithsonianmagazine Subscribe: https://www.youtube.com/@SmithsonianMagazine Read more about the history of the Ouija Board here: https://www.smithsonianmag.com/history/the-strange-and-mysterious-history-of-the-ouija-board-5860627/ Did you know that US Navy Officers rely on a system called the “ouija board” to track the movement of airplanes on a carrier? Learn more here: https://www.smithsonianmag.com/air-space-magazine/how-things-work-the-ouija-board-10048217/ For more videos from Smithsonian Magazine: https://www.smithsonianmag.com/videos/ Get More Smithsonian Magazine: Official Site: https://www.smithsonianmag.com/ Facebook: https://www.facebook.com/smithsonianmagazine/ X: https://x.com/smithsonianmag Instagram: https://www.instagram.com/SmithsonianMagazine/ Digital Editorial Director: Brian Wolly Director of Programming: Nicki Marko Manager of Programming: Michelle Mehrtens Scriptwriter: Dan Wolf Video Editor: Adam Benavides Full Article
obs Cosmic Blobs Cited as 'Breakthrough Product' By www.solidworks.com Published On :: Mon, 04 Apr 2005 00:00:00 -0500 Software earns recognition from parents' organizations Full Article
obs Cosmic Blobs unveils 'Deluxe' Edition plus new collection of expansion packs By www.solidworks.com Published On :: Tue, 19 Sep 2006 00:00:00 -0500 New offerings present even more possibilities for powerful and fun 3D graphics software for kids Full Article
obs SOLIDWORKS Corporation donates software to Glacier Society to help cut through design obstacles By www.solidworks.com Published On :: Mon, 18 Dec 2006 00:00:00 -0500 Icebreaker would dispense desperately needed medical care to citizens in polar region countries Full Article
obs Cosmic Blobs to Target Mass-Market Retailers By www.solidworks.com Published On :: Mon, 05 Feb 2007 00:00:00 -0500 The Learning Company and Dassault Systèmes Form Strategic Licensing Agreement Full Article
obs Powerful observatory camera model wins SOLIDWORKS Design Contest 2008 By www.solidworks.com Published On :: Wed, 23 Jan 2008 00:00:00 -0500 'One Degree Imager' will help solve the universe's deepest mysteries Full Article
obs Bo-Dyn Bobsleds Use SOLIDWORKS to Design World’s Fastest Sled By www.solidworks.com Published On :: Tue, 26 Mar 2013 00:00:00 -0500 ModernTech Teaches Bo-Dyn How to Find Hundredths of a Second for a Golden Repeat Full Article
obs Dassault Systèmes’ SOLIDWORKS Drives TEAM USA Bobsled to New Speeds in Sochi By www.solidworks.com Published On :: Tue, 28 Jan 2014 00:00:00 -0500 SOLIDWORKS 3D Design Software Delivers the Precision Needed to Shave Milliseconds off Bobsled Finish Times Full Article
obs There's a Better Way: Trust-Based Observations By blogs.edweek.org Published On :: Sun, 18 Oct 2020 00:00:00 +0000 Teacher observations have long been seen as a waste of time because they provide little effective feedback. Trust-based observations take the challenges of observations into consideration and improve them. Full Article Growth+Mindset
obs One Way Recessions Actually Help Districts: Great Teachers Seeking Jobs By blogs.edweek.org Published On :: Mon, 27 Jul 2015 00:00:00 +0000 The hiring pool improved for schools when the recession squeezed teachers, study finds. Full Article Teacherquality
obs Here's How Many Teaching Jobs Could Be Lost in Each State in a COVID-19 Recession By blogs.edweek.org Published On :: Thu, 30 Apr 2020 00:00:00 +0000 There could be an 8.4 percent reduction in the U.S. teaching corps, and some states could see reductions as large as 20 percent, according to a new analysis by the Learning Policy Institute. Full Article Teachingprofession
obs NASA’s Chandra Telescope Observes Mysterious 'Knots' Blasting from Nearby Black Hole Jets By www.gadgets360.com Published On :: Tue, 12 Nov 2024 14:34:16 +0530 NASA’s Chandra X-ray Observatory has unveiled mysterious "knots" in the jet of a supermassive black hole in Centaurus A, a nearby galaxy. These bright, fast-moving features exhibit a higher speed in X-rays than in radio wavelengths, hinting at unexplored physics in black hole jets. Despite financial uncertainties surrounding Chandra's operations, scientists continue to uncover new phenomena in deep space, underscoring the telescope’s enduring value to astrophysics. Full Article