cancer Breast Cancer Drug Might Help Men on Prostate Cancer Therapy By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Breast Cancer Drug Might Help Men on Prostate Cancer TherapyCategory: Health NewsCreated: 8/28/2012 10:05:00 AMLast Editorial Review: 8/28/2012 12:00:00 AM Full Article
cancer Daily Aspirin May Help Fight Prostate Cancer, But Not Breast Cancer By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Daily Aspirin May Help Fight Prostate Cancer, But Not Breast CancerCategory: Health NewsCreated: 8/27/2012 6:05:00 PMLast Editorial Review: 8/28/2012 12:00:00 AM Full Article
cancer Race May Affect Quality of Prostate Cancer Surgical Care By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Race May Affect Quality of Prostate Cancer Surgical CareCategory: Health NewsCreated: 8/28/2012 6:05:00 PMLast Editorial Review: 8/29/2012 12:00:00 AM Full Article
cancer Afinitor Disperz Approved for Rare Pediatric Cancer By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Afinitor Disperz Approved for Rare Pediatric CancerCategory: Health NewsCreated: 8/29/2012 6:05:00 PMLast Editorial Review: 8/30/2012 12:00:00 AM Full Article
cancer Breast Cancer Drug May Harm the Heart More Than Thought By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Breast Cancer Drug May Harm the Heart More Than ThoughtCategory: Health NewsCreated: 8/30/2012 6:05:00 PMLast Editorial Review: 8/31/2012 12:00:00 AM Full Article
cancer Too Few Girls Get HPV Vaccine Against Cancer: CDC By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Too Few Girls Get HPV Vaccine Against Cancer: CDCCategory: Health NewsCreated: 8/30/2012 4:05:00 PMLast Editorial Review: 8/31/2012 12:00:00 AM Full Article
cancer New Hope for Early Detection of Ovarian Cancer By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: New Hope for Early Detection of Ovarian CancerCategory: Health NewsCreated: 8/26/2013 9:35:00 AMLast Editorial Review: 8/26/2013 12:00:00 AM Full Article
cancer Could Heavy Coffee Drinking Help Men Battle Prostate Cancer? By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Could Heavy Coffee Drinking Help Men Battle Prostate Cancer?Category: Health NewsCreated: 8/26/2013 7:36:00 PMLast Editorial Review: 8/27/2013 12:00:00 AM Full Article
cancer Terms Docs Use Can Influence Patients' Cancer Choices By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Terms Docs Use Can Influence Patients' Cancer ChoicesCategory: Health NewsCreated: 8/26/2013 4:36:00 PMLast Editorial Review: 8/27/2013 12:00:00 AM Full Article
cancer Hodgkin Lymphoma Treatment Tied to Higher Risk of Stomach Cancer in Study By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Hodgkin Lymphoma Treatment Tied to Higher Risk of Stomach Cancer in StudyCategory: Health NewsCreated: 8/28/2013 9:35:00 AMLast Editorial Review: 8/28/2013 12:00:00 AM Full Article
cancer Drinking Before First Pregnancy Raises Risk of Breast Cancer: Study By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Drinking Before First Pregnancy Raises Risk of Breast Cancer: StudyCategory: Health NewsCreated: 8/28/2013 4:35:00 PMLast Editorial Review: 8/29/2013 12:00:00 AM Full Article
cancer Polyp Removal Doesn't Always Signal Raised Colon Cancer Risk, Study Says By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Polyp Removal Doesn't Always Signal Raised Colon Cancer Risk, Study SaysCategory: Health NewsCreated: 8/27/2014 5:36:00 PMLast Editorial Review: 8/28/2014 12:00:00 AM Full Article
cancer Light Therapy a Good Option for Pre-Cancerous Skin Lesions, Study Says By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Light Therapy a Good Option for Pre-Cancerous Skin Lesions, Study SaysCategory: Health NewsCreated: 8/27/2014 4:35:00 PMLast Editorial Review: 8/28/2014 12:00:00 AM Full Article
cancer Low-Dose Aspirin, Other Painkillers May Lower Colon Cancer Risk By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Low-Dose Aspirin, Other Painkillers May Lower Colon Cancer RiskCategory: Health NewsCreated: 8/24/2015 12:00:00 AMLast Editorial Review: 8/25/2015 12:00:00 AM Full Article
cancer Blood Pressure Drugs Linked to Longer Ovarian Cancer Survival By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Blood Pressure Drugs Linked to Longer Ovarian Cancer SurvivalCategory: Health NewsCreated: 8/24/2015 12:00:00 AMLast Editorial Review: 8/25/2015 12:00:00 AM Full Article
cancer Acupuncture Best for Hot Flashes in Breast Cancer Survivors: Study By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Acupuncture Best for Hot Flashes in Breast Cancer Survivors: StudyCategory: Health NewsCreated: 8/25/2015 12:00:00 AMLast Editorial Review: 8/26/2015 12:00:00 AM Full Article
cancer Experimental Drug for Blood Cancer Shows Promise By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Experimental Drug for Blood Cancer Shows PromiseCategory: Health NewsCreated: 8/26/2015 12:00:00 AMLast Editorial Review: 8/27/2015 12:00:00 AM Full Article
cancer Childhood Cancer Survivors Who've Had One Stroke at Risk of Second By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Childhood Cancer Survivors Who've Had One Stroke at Risk of SecondCategory: Health NewsCreated: 8/26/2015 12:00:00 AMLast Editorial Review: 8/27/2015 12:00:00 AM Full Article
cancer Blood Test May One Day Predict Breast Cancer Relapse By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Blood Test May One Day Predict Breast Cancer RelapseCategory: Health NewsCreated: 8/26/2015 12:00:00 AMLast Editorial Review: 8/27/2015 12:00:00 AM Full Article
cancer Black Women at Raised Risk of Carrying Breast Cancer Genes By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Black Women at Raised Risk of Carrying Breast Cancer GenesCategory: Health NewsCreated: 8/27/2015 12:00:00 AMLast Editorial Review: 8/28/2015 12:00:00 AM Full Article
cancer Longer Colonoscopy Time May Cut Cancer Risk By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Longer Colonoscopy Time May Cut Cancer RiskCategory: Health NewsCreated: 8/27/2015 12:00:00 AMLast Editorial Review: 8/28/2015 12:00:00 AM Full Article
cancer Fewer Cancer-Causing Chemicals in E-Cigs Than Regular Cigarettes: Study By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Fewer Cancer-Causing Chemicals in E-Cigs Than Regular Cigarettes: StudyCategory: Health NewsCreated: 8/19/2016 12:00:00 AMLast Editorial Review: 8/22/2016 12:00:00 AM Full Article
cancer Use of Cancer-Linked Fibroid Device Declines After FDA Warning By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Use of Cancer-Linked Fibroid Device Declines After FDA WarningCategory: Health NewsCreated: 8/23/2016 12:00:00 AMLast Editorial Review: 8/24/2016 12:00:00 AM Full Article
cancer Excess Weight Tied to Higher Risk for Many Cancers, Experts Say By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Excess Weight Tied to Higher Risk for Many Cancers, Experts SayCategory: Health NewsCreated: 8/24/2016 12:00:00 AMLast Editorial Review: 8/25/2016 12:00:00 AM Full Article
cancer Cancer on Course to Become Top Killer of Americans By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Cancer on Course to Become Top Killer of AmericansCategory: Health NewsCreated: 8/24/2016 12:00:00 AMLast Editorial Review: 8/25/2016 12:00:00 AM Full Article
cancer Hopes Dashed for Rare Bone Cancer Treatment By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Hopes Dashed for Rare Bone Cancer TreatmentCategory: Health NewsCreated: 8/26/2016 12:00:00 AMLast Editorial Review: 8/26/2016 12:00:00 AM Full Article
cancer Common Treatment for Early Prostate Cancer May Carry Heart Risk By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Common Treatment for Early Prostate Cancer May Carry Heart RiskCategory: Health NewsCreated: 8/25/2017 12:00:00 AMLast Editorial Review: 8/28/2017 12:00:00 AM Full Article
cancer Science Weighs in On How Fat Raises Cancer Risk By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Science Weighs in On How Fat Raises Cancer RiskCategory: Health NewsCreated: 9/1/2017 12:00:00 AMLast Editorial Review: 9/1/2017 12:00:00 AM Full Article
cancer Bills Mount for Breast Cancer Survivors By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Bills Mount for Breast Cancer SurvivorsCategory: Health NewsCreated: 8/24/2018 12:00:00 AMLast Editorial Review: 8/27/2018 12:00:00 AM Full Article
cancer Health Tip: Talking About Your Cancer Diagnosis By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Health Tip: Talking About Your Cancer DiagnosisCategory: Health NewsCreated: 8/28/2018 12:00:00 AMLast Editorial Review: 8/28/2018 12:00:00 AM Full Article
cancer Is Teen Drinking Tied to Aggressive Prostate Cancer Later in Life? By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Is Teen Drinking Tied to Aggressive Prostate Cancer Later in Life?Category: Health NewsCreated: 8/29/2018 12:00:00 AMLast Editorial Review: 8/29/2018 12:00:00 AM Full Article
cancer Justice Ruth Bader Ginsburg Treated for Pancreatic Cancer By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Justice Ruth Bader Ginsburg Treated for Pancreatic CancerCategory: Health NewsCreated: 8/23/2019 12:00:00 AMLast Editorial Review: 8/26/2019 12:00:00 AM Full Article
cancer Childhood Cancer Survivors Struggle With Heart Troubles By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Childhood Cancer Survivors Struggle With Heart TroublesCategory: Health NewsCreated: 8/26/2019 12:00:00 AMLast Editorial Review: 8/27/2019 12:00:00 AM Full Article
cancer Men Should be Included in Breast Cancer Clinical Trials: FDA By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Men Should be Included in Breast Cancer Clinical Trials: FDACategory: Health NewsCreated: 8/26/2019 12:00:00 AMLast Editorial Review: 8/27/2019 12:00:00 AM Full Article
cancer Exercise Is Good Medicine for Advanced Colon Cancer By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Exercise Is Good Medicine for Advanced Colon CancerCategory: Health NewsCreated: 8/28/2019 12:00:00 AMLast Editorial Review: 8/28/2019 12:00:00 AM Full Article
cancer Can Breast Cancer Be a Risk Factor for Opioid Use Among Older Patients? By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Can Breast Cancer Be a Risk Factor for Opioid Use Among Older Patients?Category: Health NewsCreated: 8/27/2019 12:00:00 AMLast Editorial Review: 8/28/2019 12:00:00 AM Full Article
cancer Many Thyroid Cancer Ultrasound Scans Unnecessary By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Many Thyroid Cancer Ultrasound Scans UnnecessaryCategory: Health NewsCreated: 8/25/2020 12:00:00 AMLast Editorial Review: 8/26/2020 12:00:00 AM Full Article
cancer Cancer Radiation Can Safely Proceed During COVID-19 Pandemic: Study By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Cancer Radiation Can Safely Proceed During COVID-19 Pandemic: StudyCategory: Health NewsCreated: 8/27/2020 12:00:00 AMLast Editorial Review: 8/28/2020 12:00:00 AM Full Article
cancer Spotting the Signs of Deadly Melanoma Skin Cancers By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Spotting the Signs of Deadly Melanoma Skin CancersCategory: Health NewsCreated: 8/22/2021 12:00:00 AMLast Editorial Review: 8/23/2021 12:00:00 AM Full Article
cancer Exercise Could Help Fight 'Chemo Brain' in Breast Cancer Patients By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Exercise Could Help Fight 'Chemo Brain' in Breast Cancer PatientsCategory: Health NewsCreated: 8/25/2021 12:00:00 AMLast Editorial Review: 8/25/2021 12:00:00 AM Full Article
cancer Enlarged Prostate Doesn't Raise a Man's Odds for Cancer: Study By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Enlarged Prostate Doesn't Raise a Man's Odds for Cancer: StudyCategory: Health NewsCreated: 8/25/2021 12:00:00 AMLast Editorial Review: 8/25/2021 12:00:00 AM Full Article
cancer Cases of Advanced Cervical Cancer Keep Rising Among U.S. Women By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Cases of Advanced Cervical Cancer Keep Rising Among U.S. WomenCategory: Health NewsCreated: 8/19/2022 12:00:00 AMLast Editorial Review: 8/22/2022 12:00:00 AM Full Article
cancer Blood Protein Might Predict Future Diabetes, Cancer Risk By www.medicinenet.com Published On :: Fri, 5 Aug 2022 00:00:00 PDT Title: Blood Protein Might Predict Future Diabetes, Cancer RiskCategory: Health NewsCreated: 8/5/2022 12:00:00 AMLast Editorial Review: 8/5/2022 12:00:00 AM Full Article
cancer What Are the 5 Warning Signs of Bladder Cancer? By www.medicinenet.com Published On :: Wed, 8 Jun 2022 00:00:00 PDT Title: What Are the 5 Warning Signs of Bladder Cancer?Category: Diseases and ConditionsCreated: 4/22/2021 12:00:00 AMLast Editorial Review: 6/8/2022 12:00:00 AM Full Article
cancer New Approach Cuts Odds for Anal Cancer in People With HIV By www.medicinenet.com Published On :: Thu, 16 Jun 2022 00:00:00 PDT Title: New Approach Cuts Odds for Anal Cancer in People With HIVCategory: Health NewsCreated: 6/16/2022 12:00:00 AMLast Editorial Review: 6/16/2022 12:00:00 AM Full Article
cancer How to Manage Menopause Symptoms After Breast Cancer By www.medicinenet.com Published On :: Thu, 7 Jul 2022 00:00:00 PDT Title: How to Manage Menopause Symptoms After Breast CancerCategory: Diseases and ConditionsCreated: 7/7/2022 12:00:00 AMLast Editorial Review: 7/7/2022 12:00:00 AM Full Article
cancer Chromatin interaction maps identify oncogenic targets of enhancer duplications in cancer [RESEARCH] By genome.cshlp.org Published On :: 2024-10-29T06:46:07-07:00 As a major type of structural variants, tandem duplication plays a critical role in tumorigenesis by increasing oncogene dosage. Recent work has revealed that noncoding enhancers are also affected by duplications leading to the activation of oncogenes that are inside or outside of the duplicated regions. However, the prevalence of enhancer duplication and the identity of their target genes remains largely unknown in the cancer genome. Here, by analyzing whole-genome sequencing data in a non-gene-centric manner, we identify 881 duplication hotspots in 13 major cancer types, most of which do not contain protein-coding genes. We show that the hotspots are enriched with distal enhancer elements and are highly lineage-specific. We develop a HiChIP-based methodology that navigates enhancer–promoter contact maps to prioritize the target genes for the duplication hotspots harboring enhancer elements. The methodology identifies many novel enhancer duplication events activating oncogenes such as ESR1, FOXA1, GATA3, GATA6, TP63, and VEGFA, as well as potentially novel oncogenes such as GRHL2, IRF2BP2, and CREB3L1. In particular, we identify a duplication hotspot on Chromosome 10p15 harboring a cluster of enhancers, which skips over two genes, through a long-range chromatin interaction, to activate an oncogenic isoform of the NET1 gene to promote migration of gastric cancer cells. Focusing on tandem duplications, our study substantially extends the catalog of noncoding driver alterations in multiple cancer types, revealing attractive targets for functional characterization and therapeutic intervention. Full Article
cancer Colorectal Cancer Screening: A Multicomponent Intervention to Increase Uptake in Patients Aged 45-49 By www.jabfm.org Published On :: 2024-10-25T09:26:14-07:00 Purpose: Colorectal cancer (CRC) screening is recommended starting at age 45, but there has been little research on strategies to promote screening among patients younger than 50. This study assessed the effect of a multicomponent intervention on screening completion in this age group. Methods: The intervention consisted of outreach to patients aged 45 to 49 (n = 3,873) via mailed fecal immunochemical test (FIT) (sent to 46%), text (84%), e-mail (53%), and the extension to this age group of an existing standing order protocol allowing primary care nurses and medical assistants to order FIT at primary care clinics in an urban safety-net system. We used segmented linear regression to assess changes in CRC screening completion trends. Patients aged 51 to 55 were included as a comparison group (n = 3,943). Data were extracted from the EHR. Results: The percentage of patients aged 45 to 49 who were up-to-date with CRC screening (colonoscopy in 10 years or FIT in last year) increased an average of 0.4% (95% CI 0.3, 0.6)) every 30 days before intervention rollout and 2.8% (95% CI 2.5, 3.1) after (slope difference 2.3% [95% CI 2.0, 2.7]). This difference persisted after accounting for small changes in the outcome observed in the comparison group (slope difference 1.7% [95% CI 1.2, 2.2]). Conclusions: These results suggest that the intervention increased CRC screening completion among patients 45 to 49. Health care systems seeking to improve CRC screening participation among patients aged 45 to 49 should consider implementing similar interventions. Full Article
cancer Harnessing brain-body communication to understand cancer [Special Section: Symposium Outlook] By genesdev.cshlp.org Published On :: 2024-10-16T07:18:56-07:00 Solid tumors that arise in the body interact with neurons, which influences cancer progression and treatment response. Here, we discuss key questions in the field, including defining the nature of interactions between tumors and neural circuits and defining how neural signals shape the tumor microenvironment. This information will allow us to optimally target neural signaling to improve outcomes for cancer patients. Full Article
cancer Bridging brain and body in cancer [Special Section: Symposium Outlook] By genesdev.cshlp.org Published On :: 2024-10-16T07:18:56-07:00 Recent work has highlighted the central role the brain–body axis plays in not only maintaining organismal homeostasis but also coordinating the body's response to immune and inflammatory insults. Here, we discuss how science is poised to address the many ways that our brain is directly involved with disease. In particular, we feel that combining cutting-edge tools in neuroscience with translationally relevant models of cancer will be critical to understanding how the brain and tumors communicate and modulate each other's behavior. Full Article
