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ca Ultra-efficient delivery of CRISPR/Cas9 using ionic liquid conjugated polymers for genome editing-based tumor therapy By pubs.rsc.org Published On :: Biomater. Sci., 2024, 12,1716-1725DOI: 10.1039/D3BM01981K, PaperZhongming Huang, Tongren Yang, Jie Yu, Yijian Gao, Yuhua Weng, Yuanyu Huang, Shengliang LiThrough molecular screening, ionic liquid-conjugated polymers (IL-CPs) are developed for highly efficient delivery of CRISPR/Cas9 system, which demonstrated high-performance genome editing-based tumor therapy.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ca A highly tuneable inverse emulsion polymerization for the synthesis of stimuli-responsive nanoparticles for biomedical applications By pubs.rsc.org Published On :: Biomater. Sci., 2024, 12,1707-1715DOI: 10.1039/D3BM01765F, PaperAndrew C. Murphy, Heidi F. Oldenkamp, Nicholas A. PeppasThis article demonstrates an inverse emulsion scheme to polymerize a variety of ionizable and non-ionizable monomers to form stimuli-responsive nanoparticles with potential applications in biomaterials science.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ca Applications of peptide-based nanomaterials in targeting cancer therapy By pubs.rsc.org Published On :: Biomater. Sci., 2024, 12,1630-1642DOI: 10.1039/D3BM02026F, Review ArticleBeilei Sun, Limin Zhang, Mengzhen Li, Xin Wang, Weizhi WangTo meet the precise diagnosis and treatment as well as reduce systemic toxicity and side effects, self-assembled peptides are applied to the targeting therapy, including targeting theranostics, nanocarrier delivery, immunotherapy, and combination therapy.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ca Comparative analysis of supercritical fluid-based and chemical-based decellularization techniques for nerve tissue regeneration By pubs.rsc.org Published On :: Biomater. Sci., 2024, 12,1847-1863DOI: 10.1039/D3BM02072J, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Beom-Seok Kim, Jeong-Uk Kim, Jae Woo Lee, Kyung Min Ryu, Rachel H. Koh, Kyoung-Ha So, Nathaniel S. HwangThe supercritical (SC) fluid-based method were utilized for nerve tissue decellualrization. In vitro, vivo assessments underscore its potential for advanced tissue engineering and regenerative applications.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ca Self-assembled nanodrug delivery systems for anti-cancer drugs from traditional Chinese medicine By pubs.rsc.org Published On :: Biomater. Sci., 2024, 12,1662-1692DOI: 10.1039/D3BM01451G, Review ArticleQiao Li, Yuan Lianghao, Gao Shijie, Wang Zhiyi, Tang Yuanting, Chen Cong, Zhao Chun-Qin, Fu XianjunIn this review, we have summarized the common self-assembled mechanism of NSMs-based SANDDSs. Meanwhile, the potential applications for cancer treatment and future development prospects are also prospected.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ca Copper(II)-based metal–organic framework delivery of calcium ascorbate for enhanced chemodynamic therapy via H2O2 self-supply and glutathione depletion By pubs.rsc.org Published On :: Biomater. Sci., 2024, 12,1871-1882DOI: 10.1039/D3BM01922E, PaperMeng Zhang, Hongjin Xue, Jiaxin Yang, Xin Zhao, Mei Xue, Wei Sun, Jianfeng Qiu, Zhihong ZhuA Cu/ZIF-8/Vc-Ca/HA nanosystem synchronously releases Fenton catalytic Cu2+ and Vc-Ca to achieve improved chemodynamic therapy via H2O2 self-supply and GSH depletion.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ca Free drug and ROS-responsive nanoparticle delivery of synergistic doxorubicin and olaparib combinations to triple negative breast cancer models By pubs.rsc.org Published On :: Biomater. Sci., 2024, 12,1822-1840DOI: 10.1039/D3BM01931D, Paper Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Robert J. Cavanagh, Patrícia F. Monteiro, Cara Moloney, Alessandra Travanut, Fatemeh Mehradnia, Vincenzo Taresco, Ruman Rahman, Stewart G. Martin, Anna M. Grabowska, Marianne B. Ashford, Cameron AlexanderCombinations of the topoisomerase II inhibitor doxorubicin and the poly (ADP-ribose) polymerase inhibitor olaparib offer potential drug–drug synergy for treatment of triple negative breast cancers (TNBC) both in free drug form and when delivered by oxidation-responsive nanoparticles.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ca Ferroptosis and ferroptosis-inducing nanomedicine as a promising weapon in combination therapy of prostate cancer By pubs.rsc.org Published On :: Biomater. Sci., 2024, 12,1617-1629DOI: 10.1039/D3BM01894F, Review ArticleMengjun Huang, Qiliang Teng, Fei Cao, Jinsheng Huang, Jun PangExisting treatments could be sensitized by targeting the ferroptosis pathway in prostate cancer.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ca Sorafenib and tetrakis (4-carboxyphenyl) porphyrin assembled nanoparticles for synergistic targeted chemotherapy and sonodynamic therapy of hepatocellular carcinoma By pubs.rsc.org Published On :: Biomater. Sci., 2024, 12,1864-1870DOI: 10.1039/D3BM01994B, PaperYongzhi Chen, Qiuxia Tan, Yuanyu Tang, E. Pang, Rui Peng, Minhuan Lan, Dousheng BaiHepatocellular carcinoma (HCC) is characterized by a high degree of malignancy and mortality.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ca Self-adjuvanted L-arginine-modified dextran-based nanogels for sustained local antigenic protein delivery to antigen-presenting cells and enhanced cellular and humoral immune responses By pubs.rsc.org Published On :: Biomater. Sci., 2024, 12,1771-1787DOI: 10.1039/D3BM01150J, PaperJin Teng Chung, Mehrnoosh Rafiei, Ying ChauAntigens are delivered in self-adjuvanted arginine-modified dextran-based nanogels to the dendritic cells in promoting antigen specific cellular immunity.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ca Application of a meshed artificial dermal scaffold and negative-pressure wound therapy in the treatment of full-thickness skin defects: a prospective in vivo study By pubs.rsc.org Published On :: Biomater. Sci., 2024, 12,1914-1923DOI: 10.1039/D3BM01675G, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Pei Wei, Lijiao Wu, Hongteng Xie, Zhaohong Chen, Rongwei Tan, Zhaorong XuA novel meshed ADS combined with NPWT can reduce the risk of scaffold-related complications, which helps to improve the quality of wound repair and promotes a broader range of applications.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
