New England has a negative point differential heading into Week 4 for the first time since 2008.

Expectations were high for Jacksonville heading into the season. The game charters at Pro Football Focus ranked them as the league’s top secondary, the second-best pass rush and the seventh-best run-stopping unit in 2018.

Goff started the season with 941 yards and six touchdowns over his first three games then completed 26 of his 33 passes against the Minnesota Vikings for 465 yards and five touchdowns in Week 4.

Getting a jump on early lines can give bettors added value in their wagering. Here are three teams to focus on for Week 5.

Smith has lived up to expectations in 2018, completing 66 of 96 passes (career-high 69 percent) for 767 yards, four touchdowns and one interception.

The Patriots put their stamp back on the AFC East after throttling the Miami Dolphins 38-7 on Sunday. The Colts are next.

Contrarian bettors are off to their best start through the first four weeks of the season since 2003.

Anderson has had to face Darius Slay, Xavien Howard, Denzel Ward and Jalen Ramsey in coverage during the first four weeks of the season. Better days should be ahead, starting next week against the Colts.

Khalil Mack has helped turn the Bears into a solid commodity in the betting market.

Prescott's touchdown rate is down and his interception rate is up for the second straight season.

Cam Newton is 4-0 against the Redskins, with 11 touchdowns (nine passing, two rushing) and zero interceptions for his career.

Houston’s defensive front, featuring one-man wrecking crew J.J. Watt, has the sixth-highest adjusted sack rate.

The work of Chargers quarterback Philip Rivers shouldn’t go unnoticed.

Michel will face a Chicago Bears defense that stops opposing rushers a league-low 13 percent of the time.

Colts have the the fifth-best run-stopping unit per PFF and the fourth-highest stuff rate per Football Outsiders.

Goff is using play-action more often than any other quarterback in 2018.

Mack carried the ball 19 times for 126 yards and a touchdown and added two catches for 33 yards and a touchdown on Sunday against the Bills.

Boston's pitchers aren't performing as well as they did during the regular season, making them vulnerable to an upset by Los Angeles.

Washington is a good bet to win at least two of their next three games (42 percent chance), with 3-to-1 odds to win all three.

Thomas and the Saints will have to contend with a Vikings defense that has limited No. 1 receivers to an average of 53 yards per game.

Pittsburgh is stuffing 25 percent of rushers in 2018, eighth-most in the NFL.

Giants' offensive line is allowing an adjusted sack rate of over eight percent, the eighth-worst in the NFL.

A.J. Green and Tyler Boyd (Cincinnati Bengals) plus Odell Beckham Jr. (New York Giants) are among the top fantasy receivers off next week.

The Seahawks are barely over .500, but they measure up in a critical statistic that has helped narrow the field of likely Super Bowl teams.

Accelerate, the 5-2 favorite in the final Breeders' Cup Classic future wagering pool, is coming off a big win as the 3-10 favorite in the Awesome Again Stakes at Saratoga. But should you bet him?

Six teams are on a bye this week, giving stars like Saquon Barkley, Odell Beckham Jr., Andrew Luck, Zach Ertz and A.J. Green the week off. Here are three players that could have big games in their stead.

According to Football Outsiders, Atlanta has the second-worst defense this season after adjusting its performance for strength of schedule.

Against No. 1 receiver types like Mike Evans, the Panthers rank fourth-best per Football Outsiders' Defense-adjusted Value Over Average.

This year’s Classic, a 1¼-mile race for 3-year-olds and up, will be held at Churchill Downs and features several strong entrants.

Favorites have won 99 of 318 races (31 percent) in the Breeders’ Cup.

The dismissal of coach Hue Jackson seems to have given Duke Johnson Jr. new life with the Browns.

The Saints' defense has some work to do — it is allowing 2.5 points per drive, fourth-most in the NFL — but New Orleans compensates for that by scoring 3.3 points per drive on offense, second-most after the Kansas City Chiefs.

Milwaukee has embraced the modern NBA.

The Braves' Acuna appears to be a runaway winner right now, but a closer look shows Soto had a tremendous impact on the Nationals.

It's a bad week to own a Washington skill position player, but a great time to get Tevin Coleman and other into your lineup.

Kansas City's opponent, Arizona, is scoring slightly more than a point per possession, making it the NFL's second-worst offense.

Pittsburgh has had trouble with the strengths of Carolina's offense.

The Bills, Browns, Patriots, Jets and 49ers all have byes. That leaves a number of holes to plug in your fantasy lineup.

Golden State has had one of the best offenses for the past five years and has done so while slowly moving away from the pick-and-roll.

Lamar Jackson, the 2016 Heisman Trophy winner and first round pick in the 2018 NFL draft, produced 117 rushing yards against the Bengals. Fantasy owners should take notice.

The Colts' QB is playing at an MVP level, completing 83 of 112 attempts (74 percent) for 977 yards, 13 touchdowns and one interception during the Colts' four-game winning streak.

Last Sunday, Jameis Winston started the game on the Buccaneers' bench. Here's why he needs to be in your lineup this week.

Washington will be without their starting right guard, right tackle, left guard, left tackle, center and starting quarterback on Sunday, making the Dallas defense a very solid pickup.

The Chargers are scoring 2.4 points per drive, the sixth-most this season, and are only forced to go three-and-out once out of every four drives.

Since 2002, the year the league expanded to 32 teams, favorites playing on Thanksgiving are 28-12 against the spread.

The running back situation in Philadelphia is gaining clarity, and the starter is available in more than a third of fantasy leagues.

Since 2002, the first year the league expanded to 32 teams, the Chargers have made the playoffs six times, just one of which saw them advance further than the divisional round. That could change this season.

Baltimore has a good chance at nine wins with 10 and possibly 11 wins within reach.

If you were relying on Jaguars running back Leonard Fournette to help you this week you’re going to need a back up plan.

Even with the Dolphins, Broncos, Bengals and Titans within striking distance, if you are hoping for a dramatic playoff push in the AFC to end the season, bad news: there won’t be any.