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Cardamonin protects against diabetic cardiomyopathy by activating macrophage NRF2 signaling through molecular interaction with KEAP1

Food Funct., 2024, 15,11083-11095
DOI: 10.1039/D4FO03543G, Paper
Wenshan Nan, Jialin Yin, Wenhao Hao, Huali Meng, Junduo Wu, Xiao Yin, Hao Wu
Cardamonin inhibited macrophage M1 polarization in diabetic cardiomyopathy by binding to KEAP1, leading to the dissociation of NRF2 from KEAP1. This promoted NRF2 nuclear translocation and antioxidant gene expression in M1 polarized macrophages.
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Solid-state fermentation of green lentils by Lactiplantibacillus plantarum leads to formation of distinct peptides that are absorbable and enhances DPP-IV inhibitory activity in an intestinal Caco-2 cell model

Food Funct., 2024, 15,11220-11235
DOI: 10.1039/D4FO03326D, Paper
Elisa Di Stefano, Nico Hüttmann, Pieter Dekker, Monic M. M. Tomassen, Teresa Oliviero, Vincenzo Fogliano, Chibuike C. Udenigwe
In vitro gastrointestinal digestion, brush border enzyme activity, and microbial fermentation with Lactiplantibacillus plantarum influenced the peptidome of green lentils and peptide transport across the intestinal Caco-2 cell monolayer.
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Regulation of redox enzymes by nutraceuticals: a review of the roles of antioxidant polyphenols and peptides

Food Funct., 2024, 15,10956-10980
DOI: 10.1039/D4FO03549F, Review Article
Joy I. Obeme-Nmom, Raliat O. Abioye, Samanta S. Reyes Flores, Chibuike C. Udenigwe
Several nutraceutical compounds, such as polyphenols and peptides, modulate the enzymatic antioxidant defence system, providing an avenue for the development of multifunctional functional foods.
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CoQ10 bioaccessibility and Caco-2 cell uptake improved with novel medium chain triglyceride encapsulation

Food Funct., 2024, 15,10981-10986
DOI: 10.1039/D4FO02844A, Communication
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Ziqi Li, Rachel E. Kopec
Coenzyme Q10 (CoQ10), a key component of the electron transport chain, is better micellarized and absorbed by intestinal cells following novel encapsulation with MCTs + phospholipid.
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Development of Pickering water-in-oil emulsions using a dual stabilization of candelilla wax and acylated EGCG derivatives to enhance the survival of probiotics (Lactobacillus plantarum) powder

Food Funct., 2024, 15,11141-11157
DOI: 10.1039/D4FO01342E, Paper
Zhaojuan Shi, Jun Wu, Xingting Wang, Tongqiao Nie, Qingmei Zeng, Chuanxun Yuan, Risheng Jin
Candelilla wax reinforced the stability of Pickering W/O emulsions with a three-dimensional crystal network. The oil phase volume fraction of the emulsions showed dramatic differences in protecting probiotic viability from environmental stresses.
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Advances in plant-derived extracellular vesicles: isolation, composition, and biological functions

Food Funct., 2024, Advance Article
DOI: 10.1039/D4FO04321A, Review Article
Yao-Bo Zeng, Xun Deng, Li-Sha Shen, Yong Yang, Xing Zhou, Lianbao Ye, Sibao Chen, Da-Jian Yang, Guo-Qing Chen
Plant-derived extracellular vesicles (PDEVs) are nanoscale vesicles released from plant cells into the extracellular space.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Association between olive oil consumption and all-cause, cardiovascular and cancer mortality in adult subjects: a systematic review and meta-analysis

Food Funct., 2024, Advance Article
DOI: 10.1039/D4FO04161E, Paper
Andrea del Saz-Lara, Alicia Saz-Lara, Iván Cavero-Redondo, Carlos Pascual-Morena, Carmen Mazarío-Gárgoles, Francesco Visioli, María-Carmen López de las Hazas, Alberto Dávalos
Fourteen studies were systematically reviewed and seven were included in the meta-analysis. Consumption of OO is associated with a reduction of cardiovascular mortality (16%), all-cause mortality (15%) and cancer mortality (11%) in adult population.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Lacticaseibacillus paracasei JM053 alleviates osteoporosis in rats by increasing the content of soy isoflavone aglycones in fermented soymilk

Food Funct., 2024, Accepted Manuscript
DOI: 10.1039/D4FO04381B, Paper
Yaping Zheng, Shasha Cheng, Hongxuan Li, Yilin Sun, Ling Guo, Chaoxin Man, Yu Zhang, Wei Zhang, Yujun Jiang
Lacticaseibacillus paracasei JM053 has a high ability to convert soy isoflavones and can be used as a fermentation strain to ferment soymilk, thereby increasing the content of free aglycones in...
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Implications of RBI’s securities buyback

It serves in smoothening out debt redemption of the government, and with it keeping the fiscal deficit and interest rates in check




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Can Israel sustain the economic pressures of war?

Without a swift ceasefire, Israel’s economic outlook appears bleak, with long-term consequences for the wider region as well




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Can ‘BRICS Bridge’ curb dollar’s dominance?

It can be a cheaper and more efficient alternative to SWIFT for transactions, if trust and liquidity issues are sorted out




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Holistic healthcare

Govt has focussed on a citizen-centric approach




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Editorial. BRICS’ financial ambitions cannot be wished away

BRICS countries have expressed the need for developing a platform where central bank digital currencies can be linked. This will reduce intermediation costs




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Retail investors need an education

Their greed and lack of awareness has cost them dear in derivatives trading. SEBI should lead an awareness campaign




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Cash keeps pace with e-payments

It’s paradoxical that despite soaring e-transactions, the circulation of high denomination ₹500 notes has marched ahead




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Editorial. German Chancellor’s visit can boost multi-level engagement

Germany’s overtures to India are significant on various counts — geo-politics, technology sharing, immigration and trade talks




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Librarians’ vital role in the world of academics

Their part in fostering knowledge is invaluable




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Pitfalls of Congress playing the caste card

The Congress’ caste politics will only help the BJP, particularly at the national level




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Tepid FDI flows call for a policy review

The government must look beyond rules and procedures and rationalise taxation, particularly in sectors like electronics




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Another star makes a political debut

Vijay’s entry adds an interesting twist to the 2026 TN elections



  • From the Viewsroom

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What Indian trade can expect from Trump 2.0

India could well face higher tariffs on exports like textiles, chemicals, pharma and auto/engineering products




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Trump’s political comeback — a historical take

There have been spectacular comebacks in history the world over, but for now, Donald Trump carries the day




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When hobbies can be all-consuming

There must be lots of other top-class minds who were devoted to their hobbies but who never let them distract them as completely as Bibek Debroy did



  • From the Viewsroom

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Making higher education an accessible public good

Through interest subvention and guarantee cover for banks, PM-Vidyalaxmi should help create a more skilled workforce




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Captain Miller Review

When you leave the cinema hall, what stays with you is the message of inclusion and the need to stand up for your freedom, observes Divya Nair.




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Karmma Calling Review

Despite its flaws, you can watch Karmma Calling if you like the glitz and drama of the ultra-rich, notes Mohnish Singh.




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Despicable Me 4 Review

This movie is perfect for all ages. Avan Verma gives his thumbs up.




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Call Me Bae Trailer: Ananya Being Ananya

Call Me Bae: Unpretentious, easy-peasy entertainment that distracts from the ugliness of real life, vouches Mayur Sanap.




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Call Me Bae Review

Call Me Bae is a spirited new addition in guilty pleasures for the fashion-loving, rom-com starved soul, applauds Sukanya Verma.




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Punjab CM dedicates state-of-the-art Bhagwan Valmiki-ji Panorama




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Punjab on threshold of revolution in education sector: CM Mann




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PGI Chandigarh makes history with three cervical spine disc replacements




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Under new captain Badoni, Delhi looks to return to winning ways

Host will look to put in a much better show against Jharkhand than it did against Chandigarh last week, where a wretched display led to a nine-wicket defeat




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Stop the free fall: On India-Canada ties

India and Canada must not allow ties to deteriorate further 




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A mixed report card for the India-Middle East-Europe Corridor

Implementation on the northern part of the corridor, which is mostly in West Asia, is going to move slowly until the conflict subsides, while progress is faster on the eastern leg connecting the UAE and Indian ports




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Sri Lanka hires South African consultant coach

Neil McKenzie’s playing career highlights included sharing a 415-run stand with Graeme Smith against Bangladesh in 2008




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Significance of Adi Sankara




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Mercedes-Benz India introduces sportscar AMG C 63 S E at ₹1.95 crore

The Mercedes-AMG C 63 S E Performance’s hybrid powertrain merges a 2.0-litre AMG turbo engine with an Electric Drive Unit (EDU)




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Will demolish all obstacles preventing people from all castes from becoming priests: CM




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Education not a prerogative of the ‘upper caste‘, says Siddaramaiah

Ramayana, Mahabharata authored by “lower castes”, says CM




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When the Centre carried out a drive to ‘cleanse public life’ in Tamil Nadu

Immediately after the Karunanidhi government was dismissed on corruption charges, Governor K.K. Shah convened a meeting of Collectors and police officers to underscore the importance of a “clean, impartial, efficient, upright and just administration”. He said months later that he would restore Tamil Nadu’s image as the best-administered State




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Government cites 17 reasons to deny or cancel foreign fund registration of NGOs

The reasons include diversion of foreign funds for carrying out anti-development activities or inciting malicious protests and religious conversions




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EC asks police to register case against Anvar 




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Medical officers told to take measures to reduce TB burden




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AUT calls for regulation of self-financing colleges in T.N.

Association wants a fee fixation committee to regulate fees of self-financing courses in private colleges




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Cantonment MLA pushes for merger with GHMC




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Lorry catches fire near Vandavasi; 10 tonnes of onion gutted




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Elephant, calf found dead at Thenkara




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DRDO carries maiden test of land attack long range cruise missile

Complementing DRDO on the successful launch, Defence Minister Rajnath Singh said this paves the way for future indigenous cruise missile development programmes




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Bypoll candidates milk caste identity in western U.P.

Caste factor often cuts through the religious and social divide in the region’s politics