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Gestational Diabetes Mellitus and Diet: A Systematic Review and Meta-analysis of Randomized Controlled Trials Examining the Impact of Modified Dietary Interventions on Maternal Glucose Control and Neonatal Birth Weight

Jennifer M. Yamamoto
Jul 1, 2018; 41:1346-1361
Reconsidering Pregnancy With Diabetes




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ADA advocates that third-party payers modify fee schedules as dentists consider going back to work

The ADA is urging third-party payers to alter their fees to account for the increasing cost of personal protective equipment that dentists are using to protect themselves, their staff and patients.




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Brain model links herpes virus to development of Alzheimer's disease

Bio-engineered models of the human brain infected with herpes simplex virus-1 develop many of the same characteristics found in Alzheimer's disease, according to a new analysis published by Science Advances.




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Dapagliflozin Versus Placebo on Left Ventricular Remodeling in Patients With Diabetes and Heart Failure: The REFORM Trial

OBJECTIVE

To determine the effects of dapagliflozin in patients with heart failure (HF) and type 2 diabetes mellitus (T2DM) on left ventricular (LV) remodeling using cardiac MRI.

RESEARCH DESIGN AND METHODS

We randomized 56 patients with T2DM and HF with LV systolic dysfunction to dapagliflozin 10 mg daily or placebo for 1 year, on top of usual therapy. The primary end point was difference in LV end-systolic volume (LVESV) using cardiac MRI. Key secondary end points included other measures of LV remodeling and clinical and biochemical parameters.

RESULTS

In our cohort, dapagliflozin had no effect on LVESV or any other parameter of LV remodeling. However, it reduced diastolic blood pressure and loop diuretic requirements while increasing hemoglobin, hematocrit, and ketone bodies. There was a trend toward lower weight.

CONCLUSIONS

We were unable to determine with certainty whether dapagliflozin in patients with T2DM and HF had any effect on LV remodeling. Whether the benefits of dapagliflozin in HF are due to remodeling or other mechanisms remains unknown.




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Novel Use of GLP-1 Receptor Agonist Therapy in HNF4A-MODY




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AAI Corp., a division of Textron, nabs $20.7M contract modification for Navy drone program

Textron was awarded a $20.7 million contract modification Friday for work on the Navy's Unmanned Influence Sweep System and Unmanned Surface Vehicle program.




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“Merit-Based” Immigration: Trump Proposal Would Dramatically Revamp Immigrant Selection Criteria, But with Modest Effects on Numbers

The Trump administration’s plan to create a "merit-based" U.S. immigration system, lessening the longstanding focus on family reunification in favor of more economic migrants, has met with a lackluster response from Democrats and Republicans alike. This Policy Beat article explores how the Trump proposal would reshape immigration to the United States, and how it compares to selection systems in other countries and past debates about changing the U.S. system.




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Signs of Modern Human Cognition Were Found in an Indonesian Cave

Painted images of intriguing human-animal hybrids are signs of modern thought

-- Read more on ScientificAmerican.com




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K-12 Instructional Models for English Learners: What They Are and Why They Matter

Marking the release of an MPI brief, experts on this webinar examine the key features of English Learner (EL) instructional models and discuss state- and district-level approaches to supporting schools in implementing effective EL program models, with a particular focus on what is being done in New York and Madison Wisconsin. 




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Inoreader mobile apps updated to support Automatic Night Mode, Microblogs, Sort by Magic and popularity indicators.

Hey, it’s been quite some time without updates on this front, but our latest updates to our Android and iOS…




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Diapression: An Integrated Model for Understanding the Experience of Individuals With Co-Occurring Diabetes and Depression

Paul Ciechanowski
Apr 1, 2011; 29:43-49
Feature Articles




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'Pay for Success' Funding Model Focus of Policy Toolkit

The Urban Institute released a toolkit aimed at policymakers and investors interested in using private dollars to pay for public programs, such as prekindergarten.




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Source Murray Model - method for determining permitted take in the Victorian Murray, Kiewa and Ovens SDL resource units.




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Modelling carp biomass : estimates for the year 2023 / Charles R. Todd, John D. Koehn, Tim R. Brown, Ben Fanson, Shane Brooks and Ivor Stuart.




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A reproducible framework for 3D acoustic forward modelling of hard rock geological models with Madagascar / Andrew Squelch, Mahyar Madadi, Milovan Urosevic.

"A special challenge of hard rock exploration is to identify targets of interest within complex geological settings. Interpretation of the geology can be made from direct geological observations and knowledge of the area, and from 2D or 3D seismic surveys. These interpretations can be developed into 3D geological models that provide the basis for predictions as to likely targets for drilling and/or mining. To verify these predictions we need to simulate 3D seismic wave propagation in the proposed geological models and compare the simulation results to seismic survey data. To achieve this we convert geological surfaces created in an interpretation software package into discretised block models representing the different lithostratigraphic units, and segment these into discrete volumes to which appropriate density and seismic velocity values are assigned. This approach allows us to scale models appropriately for desired wave propagation parameters and to go from local to global geological models and vice versa. Then we use these digital models with forward modelling codes to undertake numerous 3D acoustic wave simulations. Simulations are performed with single shot and with exploding reflector (located on extracted geological surface) configurations" -- Summary.




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The invention of the modern dog : breed and blood in Victorian Britain / Michael Worboys, Julie-Marie Strange, & Neil Pemberton.

Dogs -- Breeding -- Great Britain -- History -- 19th century.




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Addressing modern slavery / Justine Nolan and Martijn Boersma.

Human trafficking.




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The undying : a meditation on modern illness / Anne Boyer.

Boyer, Anne, 1973-




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Australia Modern : architecture, landscape & design / Hannah Lewi & Philip Goad.

Architecture -- Australia -- History -- 20th century.




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The missing pages : the modern life of a medieval manuscript from genocide to justice / Heghnar Zeitlian Watenpaugh.

Tʻoros Ṛoslin, active 13th century.




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Iconic : modern Australian houses 1950-2000 / Karen McCartney ; photography by Michael Wee.

Architecture, Domestic -- Australia -- History -- 20th century.




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The craft of dying : the modern face of death / Lyn H. Lofland ; introduction by John Troyer ; epilogue by Ara A. Francis.

Death -- Psychological aspects.




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In the land of the lion and sun, or : Modern Persia : being experiences of life in Persia from 1866 to 1881 / by C.J. Wills.

London ; New York : Ward, Lock and Co., 1891.




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Disability in the modern world

The collection comprises 150,000 pages of primary sources, supporting materials, and archives, along with 125 hours of video relating to the history of disability.




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Early modern letters online

Early Modern Letters Online is a combined finding aid and editorial interface for basic descriptions of early modern correspondence: a collaboratively populated union catalogue of sixteenth, seventeenth, and eighteenth-century letters.




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A descriptive catalogue of wet preparations, casts, drawings, models, books, etc., contained in the Museum of the Birmingham and Midland Counties Lying-in Hospital and Dispensary for the Diseases of Women and Children / arranged and edited in compliance w

Birmingham : printed by M. Billing, 1847.




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Diarrhoea and dysentery : modern views of their pathology and treatment / by Alonzo B. Palmer.

Detroit, Mich. : G.S. Davis, 1887.




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Die Aetiologie der alteren und modernen Ophthalmologie in ihrer besonderen Bedeutung fur die Therapie / von Wilhelm Manz.

Freiburg : H.M. Poppen, 1886.




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Die Furchen und Wulste am Grosshirn des Menschen : zugleich als Erlauterung zu dem Hirnmodell / von Ad. Pansch.

Berlin : R. Oppenheim, 1879.




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Die Hämodynamik, nach Versuchen / von Alfred Wilhelm Volkmann.

Leipzig : Breitkopf und Hartel, 1850.




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Die moderne Behandlung der Nervenschwäche (Neurasthenie) der Hysterie und verwandter Leiden : mit besonderer Berücksichtigung der Luftcuren, Bäder, Anstaltsbehandlung und der Mitchell-Playfair’schen Mastkur / von Dr. Loewenfeld.

Wiesbaden : J.F. Bergmann, 1889.




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Die moderne Biologie und die Entwicklungstheorie / von Erich Wasmann.

Freiburg im Breisgau : Herder, 1904.




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Die Moderne physiologische Psychologie in Deutschland : eine historisch-kritische Untersuchung mit besonderer Berücksichtigung des Problems der Aufmerksamkeit / von W. Heinrich.

Zürich : Speidel, 1895.




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Dietetical and medical hydrology : a treatise on baths; including cold, sea, warm, hot, vapour, gas, and mud baths, also on the watery regimen, hydropathy, and pulmonary inhalation; with a description of bathing in ancient and modern times / by John Bell.

Philadelphia : Barrington and Haswell, 1850.




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Diseases and remedies : a concise survey of the most modern methods of medicine / written expressly for the drug trade by physicians and pharmacists.

London : Chemist and Druggist, 1898.




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Diseases of the nervous system : being a treatise on spasmodic, paralytic, neuralgic and mental affections : for the use of students and practitioners of medicine / by Charles Porter Hart.

London : Boericke & Tafel, 1881.




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Dispensatorium universale ad tempora nostra accommodatum, et ad formam lexici chimico-pharmaceutici redactum / Christ. Frider. Reuss.

Argentorati : Sumtibus Amandi Koenig, 1786-1787.




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A dissertation on the best mode of treating spasmodic cholera ; with a view of its history and progress, from its origin in India, in 1817 down to the present time ; together with an appendix, containing a review of Dr McCormac's pamphlet, &c / by

London : Longman, Rees, Orme, Brown, and Green, 1834.




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Documents and dates of modern discoveries in the nervous system.

London : J. Churchill, 1839.




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Du diabète phosphatique : recherches sur l'élimination des phosphates par les urines, conditions physiologiques modifiant l'élimination des phosphates, influence du régime alimentaire, variations pathologiques / par L.-J. Teiss

Paris : J.-B. Baillière, 1877.




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Du passage de quelques médicaments dans les urines : modifications qu'ils y apportent, transformations qu'ils subissent dans l'organisme / par Léopold Bruneau.

Paris : V.A. Delahaye, 1880.




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Electricity : its application in medicine and surgery : a brief and practical exposition of modern scientific electro-therapeutics / by Wellington Adams.

Detroit, Mich. : G.S. Davis, 1891.




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Elements of pathology and therapeutics being the outlines of a work, intended to ascertain the nature, causes, and most efficacious modes of prevention and cure, of the greater number of the diseases incidental to the human frame : illustrated by numerous

Bath : And sold by Underwood, London, 1825.




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Enteric fever : its prevalence and modifications, aetiology, pathology and treatment as illustrated by Army data at home and abroad / by Francis H. Welch.

London : H.K. Lewis, 1883.




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Ergebnisse von 240 operierten Lupusfällen nebst Bemerkungen zur modernen Lupusbehandlung / von Ludwig Spitzer und Alfred Jungmann.

Wien : SafÏar, 1905.




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Parce que, travestis et transgenres, notre regard sur le mode et les autres se veut teinté de respect et de douceur / Hommefleur.

Châtillon, France : Association Hommefleur, [date of publication not identified]




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UCLA's Natalie Chou on her role models, inspiring Asian-American girls in basketball

Pac-12 Networks' Mike Yam has a conversation with UCLA's Natalie Chou during Wednesday's "Pac-12 Perspective" podcast. Chou reflects on her role models, passion for basketball and how her mom has made a big impact on her hoops career.




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The limiting behavior of isotonic and convex regression estimators when the model is misspecified

Eunji Lim.

Source: Electronic Journal of Statistics, Volume 14, Number 1, 2053--2097.

Abstract:
We study the asymptotic behavior of the least squares estimators when the model is possibly misspecified. We consider the setting where we wish to estimate an unknown function $f_{*}:(0,1)^{d} ightarrow mathbb{R}$ from observations $(X,Y),(X_{1},Y_{1}),cdots ,(X_{n},Y_{n})$; our estimator $hat{g}_{n}$ is the minimizer of $sum _{i=1}^{n}(Y_{i}-g(X_{i}))^{2}/n$ over $gin mathcal{G}$ for some set of functions $mathcal{G}$. We provide sufficient conditions on the metric entropy of $mathcal{G}$, under which $hat{g}_{n}$ converges to $g_{*}$ as $n ightarrow infty $, where $g_{*}$ is the minimizer of $|g-f_{*}| riangleq mathbb{E}(g(X)-f_{*}(X))^{2}$ over $gin mathcal{G}$. As corollaries of our theorem, we establish $|hat{g}_{n}-g_{*}| ightarrow 0$ as $n ightarrow infty $ when $mathcal{G}$ is the set of monotone functions or the set of convex functions. We also make a connection between the convergence rate of $|hat{g}_{n}-g_{*}|$ and the metric entropy of $mathcal{G}$. As special cases of our finding, we compute the convergence rate of $|hat{g}_{n}-g_{*}|^{2}$ when $mathcal{G}$ is the set of bounded monotone functions or the set of bounded convex functions.




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Statistical convergence of the EM algorithm on Gaussian mixture models

Ruofei Zhao, Yuanzhi Li, Yuekai Sun.

Source: Electronic Journal of Statistics, Volume 14, Number 1, 632--660.

Abstract:
We study the convergence behavior of the Expectation Maximization (EM) algorithm on Gaussian mixture models with an arbitrary number of mixture components and mixing weights. We show that as long as the means of the components are separated by at least $Omega (sqrt{min {M,d}})$, where $M$ is the number of components and $d$ is the dimension, the EM algorithm converges locally to the global optimum of the log-likelihood. Further, we show that the convergence rate is linear and characterize the size of the basin of attraction to the global optimum.




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Generalised cepstral models for the spectrum of vector time series

Maddalena Cavicchioli.

Source: Electronic Journal of Statistics, Volume 14, Number 1, 605--631.

Abstract:
The paper treats the modeling of stationary multivariate stochastic processes via a frequency domain model expressed in terms of cepstrum theory. The proposed model nests the vector exponential model of [20] as a special case, and extends the generalised cepstral model of [36] to the multivariate setting, answering a question raised by the last authors in their paper. Contemporarily, we extend the notion of generalised autocovariance function of [35] to vector time series. Then we derive explicit matrix formulas connecting generalised cepstral and autocovariance matrices of the process, and prove the consistency and asymptotic properties of the Whittle likelihood estimators of model parameters. Asymptotic theory for the special case of the vector exponential model is a significant addition to the paper of [20]. We also provide a mathematical machinery, based on matrix differentiation, and computational methods to derive our results, which differ significantly from those employed in the univariate case. The utility of the proposed model is illustrated through Monte Carlo simulation from a bivariate process characterized by a high dynamic range, and an empirical application on time varying minimum variance hedge ratios through the second moments of future and spot prices in the corn commodity market.