3

Data | How significant were BJP’s deposit losses in 13.8% of Karnataka’s seats?

The BJP lost deposits in 38.4% of the seats it contested in Southern Karnataka




3

Andhra Pradesh Chief Minister lays foundation for three renewable energy projects with a total capacity of 5,314MW

A JV pact was also signed by the State power corporation and the National Hydropower Corporation for two pumped storage hydropower projects




3

Jammu and Kashmir UT faces 30 days worth of power cuts in a year | Data

In both the duration and number of power outages, the Union Territory’s numbers are relatively far higher




3

Telangana Assembly Elections 2023: All Muslim candidates of BRS and Congress trailing | Data

Among Muslim candidates fielded by the AIMIM, except two, others were leading




3

Bengal CM Mamata Banerjee's 'insult' at NITI Aayog meeting doesn't suit democratic norms: Sanjay Raut

The money which is distributed by the Centre belongs to the people of India. What did Maharashtra get... Our Chief Minister came back empty-handed: Shiv Sena UBT leader Sanjay Raut




3

Ludhiana woman raped after her brother elopes with accused's daughter

A man along with three family members allegedly gang-raped a woman after his daughter eloped with the victim's brother; they also recorded the act on their mobile phones




3

Tripura's connectivity project with Bangladesh may be delayed: Minister

Opening of Agartala-Akhaura rail link and Maitree bridge got further delayed due to the political turmoil and change in government in Bangladesh; this project was inaugurated by Prime Minister Narendra Modi and then Bangladesh PM Sheikh Hasina in 2023




3

'Guided tour not good': Omar Abdullah slams govt for inviting foreign diplomats to see J&K polls

This "guided tour" is not a good thing, says Omar Abdullah, alleging the Centre wants to take credit for the people's participation in these polls "which is a betrayal with the people here"



  • Jammu and Kashmir Assembly

3

AICF announces ₹3.2 crore rewards for Olympiad-winning teams

Each player from the winning teams will receive ₹25 lakh, while the captains of the men’s and women’s teams, Abhijeet Kunte and Srinath Narayanan, will be rewarded with ₹15 lakh each




3

Arjun Erigaisi is World No. 3




3

Akhil Sheoran wins rifle 3-position bronze in World Cup Final

China on top of the medals table with four gold and three bronze; India joint sixth with Denmark, with one silver and a bronze.




3

Under-23 World Wrestling Championships: Chirag Chikkara clinches gold as India shines with nine medals

Chirag Chikkara becomes the second Indian man, after Paris Olympics bronze medallist Aman Sehrawat, to win the gold at the U23 Championships.




3

President-elect Trump at 312 electoral votes, Harris at 226

Donald Trump’s victory dims the hopes of Arizona Democrats, who sought to continue their ascendance, which began with the 2018 flip of a longtime GOP-held Senate seat and continued in 2020 and 2022




3

Mauritius holds election with cost of living on everyone's minds

Mauritius parliamentary election: Economic promises, alliances, and voter expectations in the Indian Ocean archipelago




3

Democrat Marie Gluesenkamp Perez wins reelection in Washington’s closely watched 3rd District

First-term Democrat Marie Gluesenkamp Perez has won reelection in Washington state’s closely watched 3rd Congressional District




3

Israeli strikes kill 30 people, including 13 children: Gaza rescuers

Israel’s retaliatory campaign has killed 43,552 people in Gaza, most of them civilians, according to figures from the Hamas-run territory’s Health Ministry




3

Soldier with Yemen's exiled government opens fire, killing two Saudi troops, wounding another

Police in the area published pictures of the soldier, saying there was a 30-million-Yemeni-rial reward for information leading to the soldier's arrest




3

Kremlin says sees 'positive signals' from Trump on Ukraine

Kremlin spokesman Dmitry Pesko said it was hard to predict "to what extent he's going to stick to statements that he made on the campaign trail"




3

President-elect Trump to appoint former ICE director Tom Homan as U.S. 'border czar'

Mr. Homan, who served in the Trump administration for a year and a half during his first term, is also a contender for secretary of homeland security




3

ISKCON organises 'chariot parade' in Houston; draws criticism

Puri Govardhan Peeth spokesperson said the event was a "conspiracy against our religion"




3

Israel top diplomat says Palestinian state not 'realistic'

A Palestinian state would be "a Hamas state", Israeli Foreign Minister Gideon Saar said




3

South Korea's Yoon practises golf to prepare for future Trump meets

Analysts said Mr. Yoon may seek to find a way to capitalise on a personal friendship with Mr. Trump to advance Seoul's interests as Trump's "America First" foreign policy plan




3

35 dead as driver hits crowd at sports centre in South China

Police detained a 62-year-old man at the sports centre in the southern Chinese city of Zhuhai following the ramming; the suspect was dissatisfied with the split of financial assets in his divorce, according to preliminary investigation




3

Requested ₹130 crore from Centre for the development of Vijayawada GGH: Vijayawada MP Chinni

All Anganwadi centres in NTR district will get a building of their own with clean kitchens, says Chinni




3

Weak dependence [electronic resource] : with examples and applications / by Jérôme Dedecker, Paul Doukhan, Gabriel Lang, León R. José Rafael, Sana Louhichi, Clémentine Prieur

New York, NY : Springer New York, 2007




3

P3MOT-decorated metal-porphyrin-based zirconium-MOF for the efficient electrochemical detection of 4-nitrobenzaldehyde

Anal. Methods, 2024, 16,2093-2100
DOI: 10.1039/D4AY00152D, Paper
Wen-yi Chen, Xin-yu Huang, Qian Sun, En-qing Gao
Developed a novel hybrid P3MOT@PCN-222(Fe) via in situ polymerization for 4-NBA detection. Showcased broad detection range, high sensitivity, selectivity and stability, laying groundwork for environmental monitoring.
The content of this RSS Feed (c) The Royal Society of Chemistry




3

A novel isophorone-based fluorescent probe for recognizing Al3+ and its bioimaging in plants

Anal. Methods, 2024, 16,2120-2126
DOI: 10.1039/D4AY00023D, Paper
Yanna Zhao, Yuqi Wang, Yingying Zhang, Xiaowei Bai, Wentong Hou, Yuqing Huang
Aluminium ions (Al3+) are widely present in industries and daily life and are closely related to human health and environmental protection.
The content of this RSS Feed (c) The Royal Society of Chemistry




3

Study on the affinity sites of cadmium's binding to ligands by thermodynamics and nuclear magnetic resonance spectroscopy

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D3AY02253F, Paper
Jinsong Yu, Xu Huang, Xiuxiu Wu, Hui Cao, Min Yuan, Tai Ye, Fei Xu
According to the experimental parameters for the interaction of Cd(II) with ligands, the binding sites of Cys and GSH were –SH, –NH2 and –COOH, and the thermodynamic behaviour of Cd(II) with Cys/GSH in boric acid and HEPES buffers was different, exothermic in HEPES but endothermic in boric acid.
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3

Analysis of O-acetylated sialic acids by 3-nitrophenylhydrazine derivatization combined with LC-MS/MS

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00330F, Paper
Chenhao Zhao, Xingdan Wang, Jing Wu, Yeli Hu, Qiwei Zhang, Qi Zheng
The 3-NPH-labeled sialic acids produce a high abundance of reporter ions, which can improve the accuracy of quantitative analysis of O-acetylated species.
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3

An efficient electrochemical sensor based on the Ce-MOF/g-C3N5 composite for the detection of nitrofurazone

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D3AY02221H, Paper
Jianxia Gu, Yiqiong Jia, Zhanbin Jin, Tingting Wei, Yongxia Li
The Ce-MOF/g-C3N5 composite was first constructed using a simple reflux method in an oil bath, and the electrochemical sensor fabricated based on this composite shows excellent detection performance in nitrofurazone detection in practical samples.
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3

A novel ratiometric sensor for fluorimetric and visual dual-mode detection of Al3+ in environmental water based on the target-regulated formation of Eu MOFs

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00324A, Paper
Tao-Li Chen, Xiang-Juan Kong, Xin-Xin Dong, Zhi-Jie Mao, Fang-Fang Kong, Qiang Xiao
The illustration of the ratiometric sensor for fluorimetric (A) and visual detection (B) of Al3+.
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3

Construction of a stable fluorescent sensor based on CsPbBr3/CdS core/shell quantum dots for selective and sensitive detection of tetracycline in ethanol

Anal. Methods, 2024, 16,2267-2277
DOI: 10.1039/D4AY00032C, Paper
Yang He, Yangjie Li, Han Wang, Site Luo, Haihu Yu
Construction of a stable fluorescent sensor based on CsPbBr3/CdS core/shell quantum dots for selective and sensitive detection of tetracycline in ethanol via a mechanism integrating photoinduced electron transfer.
The content of this RSS Feed (c) The Royal Society of Chemistry




3

Fe3+-induced luminescence quenching in carbon dots – mechanism unveiled

Anal. Methods, 2024, 16,2349-2358
DOI: 10.1039/D3AY02202A, Paper
Varsha Raveendran P.T., Anjali C., Renuka Neeroli Kizhakayil
Luminescence quenching in carbon dots with an increase in Fe3+ concentration and the quantitative variation in luminescence intensity with added ferric ions.
The content of this RSS Feed (c) The Royal Society of Chemistry




3

A highly sensitive and selective fluorescent biosensor for breast cancer derived exosomes using click reaction of azide–CD63 aptamer and alkyne-polymer dots

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00146J, Paper
Dumei Ma, Yiting Luo, Xiaoya Zhang, Zehu Xie, Yinghua Yan, Chuan-Fan Ding
A fluorescence method based on Cu-triggered click reaction of azide modified CD63 aptamer and alkyne capped Pdots was developed for breast cancer derived exosome detection.
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The content of this RSS Feed (c) The Royal Society of Chemistry




3

More 'dead' mobile services?




3

It's a snapchatty world




3

Alia-Ranbir's Daughter Raha Turns 2

Alia Bhatt and Ranbir Kapoor's little girl Raha turned two on November 6, and we were treated to the most adorable pictures on social media.




3

Why Abhishek Missed Aishwarya's Birthday

When Aishwarya celebrated her birthday in Dubai on November 1, the speculation regarding the Abhishek-Aishwarya marital rift ran even higher.




3

'He Doesn't Have The Air He Is Raj Thackeray's Son'

'I love to meet people.'




3

Pathogenesis of Alzheimer's disease and therapeutic strategies involving traditional Chinese medicine

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00660G, Review Article
Shutang Li, Jinfei Yang
As research on AD has progressed, TCM and its active ingredients have increasingly played a crucial role in clinical treatment. This article summarizes extracts from TCM and briefly elucidates their pharmacological mechanisms against AD.
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The content of this RSS Feed (c) The Royal Society of Chemistry




3

The synthesis and bioactivities of ROCK2 inhibitors with 1,2-dithiolan-3-yl motif

RSC Med. Chem., 2024, 15,3576-3596
DOI: 10.1039/D4MD00438H, Research Article
Ruolin Cao, Fangyu Du, Zhiqiang Liu, Pengcheng Cai, Minggang Qi, Wei Xiao, Xuefei Bao, Guoliang Chen
Rho-associated coiled-coil containing kinase (ROCK) plays an important role in inflammation.
The content of this RSS Feed (c) The Royal Society of Chemistry




3

Synthesis of a celastrol derivative as a cancer stem cell inhibitor through regulation of the STAT3 pathway for treatment of ovarian cancer

RSC Med. Chem., 2024, 15,3433-3443
DOI: 10.1039/D4MD00468J, Research Article
Meijuan Liu, Na Li, Zhaoxue Wang, Shuo Wang, Shaoda Ren, Xiaojing Li
A synthetic celastrol derivative (Cel-N) attenuates cancer cell stemness, inhibits the STAT3 pathway, and exerts anti-ovarian cancer effects in cell and mouse models.
The content of this RSS Feed (c) The Royal Society of Chemistry




3

Design, synthesis and biological evaluation of a novel PSMA–PI3K small molecule drug conjugate

RSC Med. Chem., 2024, 15,3485-3494
DOI: 10.1039/D4MD00246F, Research Article
Shouguo Peng, Haixia Li, Weilu Cui, Tianning Xiong, Jiaqi Hu, Haixiang Qi, Songwen Lin, Deyu Wu, Ming Ji, Heng Xu
A novel PSMA–PI3K small molecule drug conjugate has been prepared, highlighting its potential in targeted cancer therapy.
The content of this RSS Feed (c) The Royal Society of Chemistry




3

Sidechain structure–activity relationships of cyclobutane-based small molecule αvβ3 antagonists

RSC Med. Chem., 2024, 15,3616-3624
DOI: 10.1039/D4MD00306C, Research Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Adam Throup, Manar Saleh Zraikat, Andrew Gordon, Shohreh Jafarinejad Soumehsaraei, Kathrin D. Haase, Laurence H. Patterson, Patricia A. Cooper, Katherine Hanlon, Paul M. Loadman, Mark Sutherland, Steven D. Shnyder, Helen M. Sheldrake
Cyclobutanes provide a versatile scaffold for the synthesis of small molecule integrin antagonists with good metabolic stability and in vivo tolerability.
The content of this RSS Feed (c) The Royal Society of Chemistry




3

Exploring 7β-amino-6-nitrocholestens as COVID-19 antivirals: in silico, synthesis, evaluation, and integration of artificial intelligence (AI) in drug design: assessing the cytotoxicity and antioxidant activity of 3β-acetoxynitrocholestane

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00257A, Research Article
Shahabuddin, Uzma, Mohammad Azam, Mehtab Parveen, Nurul Huda Abd Kadir, Kim Min, Mahboob Alam
In light of the ongoing pandemic caused by SARS-CoV-2, effective and clinically translatable treatments are desperately needed for COVID-19 and its emerging variants.
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The content of this RSS Feed (c) The Royal Society of Chemistry




3

Synthesis and biological evaluation of novel D-ring fused steroidal N(2)-substituted-1,2,3-triazoles

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00297K, Research Article
Branislava Tenjović, Sofija Bekić, Andjelka Ćelić, Edward Petri, Julia Scholda, Florian Kopp, Marija Sakač, Andrea Nikolić
In this study, a series of 13 new D-ring fused steroidal N(2)-substituted-1,2,3-triazoles were synthesized, characterized and evaluated for their biological activities.
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The content of this RSS Feed (c) The Royal Society of Chemistry




3

Design and synthesis of (E)-3-benzylideneindolin-2-one derivatives as potential allosteric inhibitors of Aurora A kinase

RSC Med. Chem., 2024, Accepted Manuscript
DOI: 10.1039/D4MD00373J, Research Article
YongLai Jiao, Jie Zhong, Jin-Fang Xu, Shaobo Ning, Taigang Liang, Mingzhu Zhao, Jian Zhang
The mitotic kinase Aurora A, a pivotal regulator of cell cycle, is overexpressed in various cancers and has emerged as one of the most promising targets for anticancer drug discovery....
The content of this RSS Feed (c) The Royal Society of Chemistry




3

Synthesis of cationic N-acylated thiazolidine for selective activity against Gram-positive bacteria and evaluation of N-acylation's role in membrane-disrupting activity

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00626G, Research Article
Aleena Pious, Vignesh Venkatasubramanian, Dharshini Karnan Singaravelu, Subburethinam Ramesh, Fuad Ameen, Anbazhagan Veerappan
Lipidation modulates the Gram-selective antibacterial activity of QPyNATh.
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3

meso-Substituted AB3-type phenothiazinyl porphyrins and their indium and zinc complexes photosensitising properties, cytotoxicity and phototoxicity on ovarian cancer cells

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00601A, Research Article
Open Access
Brém Balázs, Bianca Stoean (Vasile), Éva Molnár, Eva Fischer-Fodor, Ovidiu Bălăcescu, Raluca Borlan, Monica Focsan, Adriana Grozav, Patriciu Achimaş-Cadariu, Emese Gál, Luiza Gaina
New meso-substituted AB3-type phenothiazinyl porphyrins and ferrocenylvinyl phenothiazinyl porphyrin were synthesised by Suzuki–Miyaura and Mizoroki–Heck cross-coupling reactions, respectively.
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3

3-Thio-3,4,5-Trisubstituted-1,2,4-Triazoles: High Affinity Somatostatin Receptor-4 Agonist Synthesis and Structure-Activity Relationships

RSC Med. Chem., 2024, Accepted Manuscript
DOI: 10.1039/D4MD00597J, Research Article
Albert Michael Crider, Audrey Hospital, Karin Sandoval, William Neumann, Stephen Kukielski, Lejla Garic, Kristen Ingold, Matthew Dunahoo, Khush Srabony, Rafael Frare, Olivia Slater, Nathan Peel, Maria Kontoyianni, Ken Witt
Somatostatin receptor-4 (SST4) is a therapeutic target for several conditions, including Alzheimer’s disease, seizures, neuropsychiatric disorders, and pain. Our previous work on 1,2,4-triazole derivatives led to enhanced SST4 binding affinity,...
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