The 23-year-old fast-rising cricketer talks about voicing the Indian Spider-Man in the upcoming animated film Spider-Man: Across the Spider-Verse

IMAGES from the second T20I in Gqeberha played between India and South Africa on Sunday

Lockie Ferguson became the sixth New Zealander to take a T20 hat-trick as the visitors edged Sri Lanka by four wickets in a low scoring match in Dambulla.

Ajit Chouhan and Rohit Raghav shone bright as U Mumba edged out UP Yoddhas 35-33 in a nail-biting contest to open the Noida leg of Pro Kabaddi League (PKL) at the Noida Indoor Stadium in Noida on Sunday.

<strong>EXPECTATIONS</strong> First things first, it is extremely surprising that the entire soundtrack of <em>Zero</em> released on the same day as the film's arrival in theatres. Even though <strong><em>'Mere Naam Tu'</em></strong>, <strong><em>'Issaqbaazi' </em></strong>as well as <strong><em>'Husn Parcham'</em></strong> had been received quite well, somehow the makers didn't unveil the entire soundtrack with four more songs. What's further surprising is that these songs have been quite well composed as well and hence one wonders why the jukebox release was delayed. Nonetheless, let's check out what Ajay-Atul and Tanishk Bagchi along with Irshad Kamil have to offer. <img class="aligncenter wp-image-936677 size-full" title="Music Review: Zero" src="https://www.bollywoodhungama.com/wp-content/uploads/2018/12/Music-Review-Zero-005.jpg" alt="Music Review: Zero" width="720" height="405" /> <strong> MUSIC</strong> <em>Zero</em> sees a fantastic start for itself, what with <strong><em>'Mere Naam Tu'</em></strong> turning out to be the love ballad of the year. A marvellous composition by Ajay-Atul with some beautiful poetic lyrics by Irshad Kamil, <em>'Mere Naam Tu'</em> has been sung brilliantly by Abhay Jodhpurkar. In fact his voice suits Shah Rukh Khan to the T and one now waits for their further collaborations. An all-rounder of a tune which makes one play this romantic number in loop<strong>, </strong><em>'Mere Naam Tu'</em> has a grand feel to it, especially the orchestra and the chorus that emerges at the end. Chartbuster. The combo of Ajay-Atul and Irshad Kamil continues with further offering in the form of<strong><em> 'Issaqbaazi'</em></strong>. This was meant to be a huge inclusion in<em> Zero</em> considering the fact that it features Shah Rukh Khan and Salman Khan together. However, Salman has limited appearance in this song which is rendered by Sukhwinder Singh and Divya Kumar. A catchy number with a foot tapping appeal, this one has a 80s feel to it with a UP-Bihar set up. Somehow the song doesn't cover an extra distance to emerge as a huge success and just about fits into the proceedings. As for Katrina Kaif, she does get a special song indeed; what with <strong><em>'Husn Parcham'</em></strong> pretty much paying homage to her <em>'husn'</em>. Think Katrina Kaif and you expect a song like this which takes her into <em>'Sheila Ki Jawaani'</em> zone. Of course, this one with Bhoomi Trivedi as the lead singer and Raja Kumari adding with her rap is more class oriented but it a chartbuster number nonetheless. As a matter of fact after you have heard this one a couple of times, <em>'Husn Parcham'</em> comes across as a tune that Vishal-Shekhar would have composed with ease. Yet again, it is huge orchestra at play as Ajay-Atul brings on the kind of canvas that is expected out of them. A song about separation and pining heart that is rooting for true love, <strong><em>'Ann Bann' </em></strong>is a very well written number that is sung quite well too by Kunal Ganjawala. It is after a long time that one hears the singer in a biggie and he does complete justice to <em>'Ann Bann'</em> which comes as a crucial juncture in the film's narrative and adds good weight to the proceedings. A well composed, tunes and sung situational number. Tanishk Bagchi takes over from this point on and is associated with as many as three songs. First to arrive is Nusrat Fateh Ali Khan's <strong><em>'Tanha Hua'</em></strong> which is recreated by Tanishk with Jyoti Nooran and Rahat Fateh Ali Khan coming together. An excellent number which has Irshad Kamil adding on to Khwaja Parvaiz's words, <em>'Tanha Hua'</em> is a heartfelt number of pain and intensity about loneliness in love. This is the kind of number that should have been promoted long ago as it has the adequate depth and is also in Shah Rukh zone. Hope it finds its audience soon. The soundtrack only continues to get better, what with <strong><em>'Heer Badnam'</em></strong> coming next. A superb song that is sung brilliantly by Romy, it has just the kind of lyrics that one would have expected from guest lyricist Kumaar. He pours in all the pain that one feels in love and it is remarkable to hear how Romy goes about rendering this one with Tanishk Bagchi coming up with a composition that is instantly catchy and impressive. Any regrets? Well, the song is just 140 seconds long when it could have just been apt had it been much longer. Altamash Faridi concludes <em>Zero </em>on a satisfactory note with the traditional <strong><em>'Duma Dam Mast Kalandar'</em></strong>. There is something magical about this sufi outing that you are entertained each time it is played. There may have been close to half a dozen filmy outings that the song has already witnessed in last few years but you never get tired of it. Same is the case here too in Zero. <strong> OVERALL</strong> <em> Zero</em> is a complete album and is one of the best that 2018 had to offer. Had the promotion of the entire soundtrack been intensive during last couple of months, the songs may well have reached a different level altogether. Nonetheless, now that the soundtrack is out, do give it a hear for sure. <strong>OUR PICK(S)</strong> <em> Mere Naam Tu, Husn Parhcham, Tanha Hua, Heer Badnaam</em>

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• This week's most popular movies on Netflix include its original thriller "Dangerous Lies" and "Den of Thieves."
• Netflix introduced daily top lists of the most popular titles on the service in February.
• Streaming search engine Reelgood keeps track of the lists and provides Business Insider with a rundown of the week's most popular movies on Netflix every Friday.
• Visit Business Insider's homepage for more stories.

The Netflix action movie "Extraction" is pacing to be the streaming giant's biggest movie premiere ever, but it was dethroned this week as the service's most popular movie. Another Netflix original, "Dangerous Lies," stole the crown.

Netflix introduced daily top 10 lists of its most viewed movies and TV shows in February (it counts a view if an account watches at least two minutes of a title).

Every week, the streaming search engine Reelgood compiles for Business Insider a list of which movies have been most prominent on Netflix's daily lists that week. On Reelgood, users can browse Netflix's entire movie library and sort by IMDb or Rotten Tomatoes ratings.

This week's list also includes "Den of Thieves," another movie starring Gerard Butler after his "Angel Has Fallen" enjoyed a few weeks on the list.

But the real winner this week is Netflix itself, as five of the seven movies on the list are Netflix originals. 

SEE ALSO: Insiders say major questions hang over DC Universe as its parent company prepares to launch Netflix rival HBO Max

7. "The Willoughbys" (2020 — Netflix original)

Netflix description: "Four siblings with horribly selfish parents hatch a plan to get rid of them for good and form a perfectly imperfect family of their own."

Rotten Tomatoes critic score: 89%

What critics said: "Though the film-makers are indebted to Edward Gorey and Lemony Snicket — and pay musical homage to Mark Mothersbaugh's work on The Royal Tenenbaums — they find their own voice, when it counts." — London Evening Standard

6. "Murder to Mercy: The Cyntoia Brown Story" (2020 — Netflix original)

Netflix description: "After 16-year-old Cyntoia Brown is sentenced to life in prison, questions about her past, physiology and the law itself call her guilt into question."

Rotten Tomatoes critic score: 75%

What critics said: "A moving reflection of what criminal justice reform means in personal terms." — New York Times

5. "Arctic Dogs" (2019)

Netflix description: "When he stumbles upon evil Otto Von Walrus's scheme to melt the Arctic, ambitious delivery fox Swifty assembles a ragtag crew to protect the planet."

Rotten Tomatoes critic score: 13%

What critics said: "There's really not much to recommend about this film: the animation lacks texture, the score is overwrought, the plotting is scattershot, and the character design is uninspired." — AV Club

4. "Den of Thieves" (2018)

Netflix description: "A highly skilled crew of bank robbers plotting a heist at the supposedly impenetrable Federal Reserve faces off against an elite unit of L.A. cops."

Rotten Tomatoes critic score: 41%

What critics said: "It often resembles a men's rights bonding weekend more than it does a movie." — Guardian

3. "Extraction" (2020 — Netflix original)

Netflix description: "A hardened mercenary's mission becomes a soul-searching race to survive when he's sent into Bangladesh to rescue a drug lord's kidnapped son."

Rotten Tomatoes critic score: 68%

What critics said: "Illustrates an important principle in escapist entertainment: you don't have to one-up your predecessors. Sometimes, it's enough to replicate what made them successful." — Newsday

2. "All Day and a Night" (2020 — Netflix original)

Netflix description: "While serving life in prison, a young man looks back at the people, the circumstances and the system that set him on the path toward his crime."

Rotten Tomatoes critic score: 56%

What critics said: "'All Day and a Night' lingers and sometimes meanders in that gray zone, where the story can accrue texture and feeling and emerge as more than the sum of its plot mechanics." — Los Angeles Times

1. "Dangerous Lies" (2020 — Netflix original)

Netflix description: "A broke caregiver unexpectedly inherits her patient's estate, but dark secrets swirl around her newfound wealth, tangling her in deceit and danger."

Rotten Tomatoes critic score: 39%

What critics said: "Looks like it cost the amount of your monthly Netflix subscription and is as satisfying to watch as it is paying that particular bill." — Globe and Mail

Ultimately, there are no easy solutions to reigniting a Covid-19 affected economy. It is evident, however, that addressing the public health crisis is non-negotiable, writes Haroon Bhorat.

β-Glucocerebrosidase (GBA) hydrolyzes glucosylceramide (GlcCer) to generate ceramide. Previously, we demonstrated that lysosomal GBA1 and nonlysosomal GBA2 possess not only GlcCer hydrolase activity, but also transglucosylation activity to transfer the glucose residue from GlcCer to cholesterol to form β-cholesterylglucoside (β-GlcChol) in vitro. β-GlcChol is a member of sterylglycosides present in diverse species. How GBA1 and GBA2 mediate β-GlcChol metabolism in the brain is unknown. Here, we purified and characterized sterylglycosides from rodent and fish brains. Although glucose is thought to be the sole carbohydrate component of sterylglycosides in vertebrates, structural analysis of rat brain sterylglycosides revealed the presence of galactosylated cholesterol (β-GalChol), in addition to β-GlcChol. Analyses of brain tissues from GBA2-deficient mice and GBA1- and/or GBA2-deficient Japanese rice fish (Oryzias latipes) revealed that GBA1 and GBA2 are responsible for β-GlcChol degradation and formation, respectively, and that both GBA1 and GBA2 are responsible for β-GalChol formation. Liquid chromatography–tandem MS revealed that β-GlcChol and β-GalChol are present throughout development from embryo to adult in the mouse brain. We found that β-GalChol expression depends on galactosylceramide (GalCer), and developmental onset of β-GalChol biosynthesis appeared to be during myelination. We also found that β-GlcChol and β-GalChol are secreted from neurons and glial cells in association with exosomes. In vitro enzyme assays confirmed that GBA1 and GBA2 have transgalactosylation activity to transfer the galactose residue from GalCer to cholesterol to form β-GalChol. This is the first report of the existence of β-GalChol in vertebrates and how β-GlcChol and β-GalChol are formed in the brain.

Actinobacillus pleuropneumoniae (App) is the etiological agent of acute porcine pneumonia and responsible for severe economic losses worldwide. The capsule polymer of App serotype 1 (App1) consists of [4)-GlcNAc-β(1,6)-Gal-α-1-(PO4-] repeating units that are O-acetylated at O-6 of the GlcNAc. It is a major virulence factor and was used in previous studies in the successful generation of an experimental glycoconjugate vaccine. However, the application of glycoconjugate vaccines in the animal health sector is limited, presumably because of the high costs associated with harvesting the polymer from pathogen culture. Consequently, here we exploited the capsule polymerase Cps1B of App1 as an in vitro synthesis tool and an alternative for capsule polymer provision. Cps1B consists of two catalytic domains, as well as a domain rich in tetratricopeptide repeats (TPRs). We compared the elongation mechanism of Cps1B with that of a ΔTPR truncation (Cps1B-ΔTPR). Interestingly, the product profiles displayed by Cps1B suggested processive elongation of the nascent polymer, whereas Cps1B-ΔTPR appeared to work in a more distributive manner. The dispersity of the synthesized products could be reduced by generating single-action transferases and immobilizing them on individual columns, separating the two catalytic activities. Furthermore, we identified the O-acetyltransferase Cps1D of App1 and used it to modify the polymers produced by Cps1B. Two-dimensional NMR analyses of the products revealed O-acetylation levels identical to those of polymer harvested from App1 culture supernatants. In conclusion, we have established a protocol for the pathogen-free in vitro synthesis of tailored, nature-identical App1 capsule polymers.

Lens proteins become increasingly cross-linked through nondisulfide linkages during aging and cataract formation. One mechanism that has been implicated in this cross-linking is glycation through formation of advanced glycation end products (AGEs). Here, we found an age-associated increase in stiffness in human lenses that was directly correlated with levels of protein–cross-linking AGEs. α-Crystallin in the lens binds to other proteins and prevents their denaturation and aggregation through its chaperone-like activity. Using a FRET-based assay, we examined the stability of the αA-crystallin–γD-crystallin complex for up to 12 days and observed that this complex is stable in PBS and upon incubation with human lens–epithelial cell lysate or lens homogenate. Addition of 2 mm ATP to the lysate or homogenate did not decrease the stability of the complex. We also generated complexes of human αA-crystallin or αB-crystallin with alcohol dehydrogenase or citrate synthase by applying thermal stress. Upon glycation under physiological conditions, the chaperone–client complexes underwent greater extents of cross-linking than did uncomplexed protein mixtures. LC-MS/MS analyses revealed that the levels of cross-linking AGEs were significantly higher in the glycated chaperone–client complexes than in glycated but uncomplexed protein mixtures. Mouse lenses subjected to thermal stress followed by glycation lost resilience more extensively than lenses subjected to thermal stress or glycation alone, and this loss was accompanied by higher protein cross-linking and higher cross-linking AGE levels. These results uncover a protein cross-linking mechanism in the lens and suggest that AGE-mediated cross-linking of α-crystallin–client complexes could contribute to lens aging and presbyopia.

This month, OM Italy is pleased to host the launch of the OM Arts School of Mission at their base, Forterocca.

As we celebrate the triumphs of the Great Generation this weekend, Writer at Large Neil Mackay explores how we squandered their legacy, and warns that the same mistakes cannot be made again

The Hero Duet could be replaced by something that was showcased at the Auto Expo 2016 but could still be undergoing development.

Hero MotoCorp has removed three 200cc bikes from its official India website. Is it a permanent discontinuation or a temporary one? We explain!

Hero MotoCorp has extended the free service and warranty period for its customers very recently. Here's is if your bike is covered!

In addition to the prizes and rewards, Hero MotoCorp may also make it a memorable experience for the participants by putting some of the entries into production.

Hero MotoCorp has confirmed through its official website that BS6 versions of the XPulse 200T and Xtreme 200R are coming soon. No word on BS6 Xtreme 200R yet.

TVS Radeon and Hero Splendor Plus, the two popular entry-level commuters have been launched in BS6 avatars very recently. Here's how the two fare against each other on paper.

BS6 Hero Splendor iSmart has seen a price revision very recently. Here's how much it now costs over its launch price and the outgoing BS4 model.

Yamaha and Suzuki both have pulled out of the 110cc scooter space in India and this has left only five players to compete in the space.

Yamaha, Suzuki and TVS are away from this segment while Bajaj's portfolio has shrunk to only bike in the 125cc space.

While most of the two-wheeler sales in India come from thrifty commuters the likes of Hero Splendor, it is the 150-160cc segment with price tags below Rs 1 lakh that allows sporty design and a hint of performance riding.

The low-speed electric two-wheelers are the ones the company hopes will sell the highest.

If you are in the process of circling in on what to buy, we're listing some here expected to launch in May - starting from Hero Xtreme 160R streetfighter to Ducati Panigale V2.

The Hero Splendor+ gets three variants and the minor price hike is uniform across all these models.