po System, method and apparatus for computing, monitoring, measuring, optimizing and allocating power and energy for a rod pumping system By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A system and methods are provided for controlling a motor of a rod pumping system using previous RPMs of the motor and predicting an RPM of the motor; correcting a power factor of a motor of a rod pumping system; allocating energy consumption and allocating energy generation for a set of wells connected to an electricity meter using an amount of energy generated by each well; and generating an alert if a set of data is beyond a threshold for the set of data. Full Article
po Power outage detection By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A network device receives notification configuration information that includes a time interval criteria and a selected geographical area for providing power outage notifications. The network device receives, during a particular time interval, a loss-of-power alarm from a network interface device (NID) associated with a customer premises. The loss-of-power alarm includes a particular NID identifier. The network device retrieves, from a database, customer configuration information that associates the particular NID identifier with a particular address and identifies a power outage in a particular region associated with the particular address. The identifying is based on receiving the loss-of-power alarm and determining if other loss-of-power alarms have been received from other NIDs in the same region and within the particular time interval. Full Article
po Adaptive control of electrical devices to achieve desired power use characteristics By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A system and method is provided for energizing and managing digitally-controlled devices at different levels of granularity, to achieve desired power use characteristics. At the lowest level, a digitally-controlled device is energized using a variable load-sensing adaptive control (VLSAC). Operation of the device is controlled using digital signals input to the device, so that limits on parameters, such as power consumption are met. A plurality of VLSACs can be coupled to a power distribution unit (PDU), which is controlled to achieve desired levels for selected parameters, set for the PDU. Multiple PDUs can be coupled to a power conversion and regulation unit (PCRU), which can be controlled by a master control to achieve a desired power profile for an entire facility, enabling the facility to meet requirements of a utility supplying the power and thus, reducing operational costs. The VLSACs and PCRU include high efficiency power sources having low distortion. Full Article
po Acoustic characteristics setting support system and acoustic characteristics setting apparatus By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT An audio setting application of a smart phone acquires tuning data from a tuning data setting server, which meets a search condition specified by a user. The audio setting application performs filtering of tuning parameters included in the tuning data. The tuning parameters are parameters of a plurality of acoustic characteristic items of an audio apparatus, and such parameters are excluded if the parameter cannot be expected to achieve an appropriate effect when the parameter is applied to the audio apparatus. Full Article
po Apparatus, and associated method, for generating an information technology incident report By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT Apparatus, and an associated method, for generating a trouble ticket related to an IT incident. When an IT incident occurs, a worklog is formed by a reporter that enters information associated with the incident. Successive inputs, made by appropriate personnel, are made to update the status of the incident. A table-of-contents is formed, associated with the collection of entries of information. And, each entry of information is categorized, to identify the entry by an associated category. Full Article
po Vision correction method for tool center point of a robot manipulator By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A vision correction method for establishing the position of a tool center point (TCP) for a robot manipulator includes the steps of: defining a preset position of the TCP; defining a preset coordinate system TG with the preset position of the TCP as its origin; capturing a two-dimensional picture of the preset coordinate system TG to establish a visual coordinate system TV; calculating a scaling ratio λ of the vision coordinate system TV relative to the preset coordinate system TG; rotating the TCP relative to axes of the preset coordinate system TG; capturing pictures of the TCP prior to and after rotation; calculating the deviation ΔP between the preset position and actual position of the TCP; correcting the preset position and corresponding coordinate system TG using ΔP, and repeating the rotation through correction steps until ΔP is less than or equal to a maximum allowable deviation of the robot manipulator. Full Article
po Positive control of robotic surgical instrument end effector By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A method of controlling an operation of a robotically-controlled surgical instrument can include receiving a first input signal at a controller indicative of a user's readiness to actuate the surgical instrument to perform a surgical procedure, outputting an output signal from the controller to provide feedback to the user in response to the received first input signal, receiving a second input signal at the controller confirming the user's readiness to actuate the surgical instrument, outputting an actuation signal from the controller in response to receiving the second input signal, and actuating the surgical instrument to perform the surgical procedure based on the actuation signal. Full Article
po Walking robot and method for controlling posture thereof By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A walking robot having joints which move using a torque servo, a posture of the robot being stably controlled, and a method of controlling a posture of the robot. It is possible to maintain a stable angle of the upper body while keeping an erect posture and balance using the COG of the robot and the inclination and the direction of the upper body and the pelvis of the robot, even in an external variation including external force or an inclination angle of the ground. Even in a state in which terrain information is not known in advance, the robot may keep an erect posture in a direction of gravity. Even when a plane where the robot stands is gradually inclined, the postures of the upper body and the legs of the robot may be kept while actively changing the angle of the ankle joint. Full Article
po Power system stabilization By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A method of damping power system oscillations include obtaining a time synchronized damping control signal from a remote location and determining a communication time delay in receiving the time synchronized damping control signal from the remote location. The time synchronized damping control signal is then modified based on a phase compensation factor and an amplitude compensation factor determined from the time delay. Finally, a damping signal is generated based on the modified time synchronized damping control signal. Full Article
po Neutral layer polymer composition for directed self assembly and processes thereof By www.freepatentsonline.com Published On :: Tue, 16 Sep 2014 08:00:00 EDT The present invention relates to a novel polymeric composition comprising a novel polymer having two or more repeat units and a terminus having the structure (1): wherein R1 represents a C1-C20 substituted or unsubstituted alkyl group, w is a number from 1-8, X is oxygen (O) or nitrogen (N), and Rd is a reactive group. The invention also relates to a process for forming a pattern using the novel polymeric composition. The invention further relates to a process of making the novel polymer. Full Article
po Alkali earth metal precursors for depositing calcium and strontium containing films By www.freepatentsonline.com Published On :: Tue, 07 Oct 2014 08:00:00 EDT Methods and compositions for the deposition of a film on a substrate. In general, the disclosed compositions and methods utilize a precursor containing calcium or strontium. Full Article
po Manufacture and use of modified polysaccharide chitosan bonds and a process to improve the preparation of HES-medicinal substance compounds By www.freepatentsonline.com Published On :: Tue, 14 Oct 2014 08:00:00 EDT The invention relates to a bonding product suitable as a carrier for medicinal substances and to the compound derived therefrom that carries medicinal substances. The invention further relates to a process and device for preparing such bonding products and compounds. Further, the invention relates to a pharmaceutical composition containing such bonding products and compounds, and to the use thereof for preparing an infusible medicament for treating a disease. Full Article
po Methods and compositions for diagnostic and therapeutic targeting of COX-2 By www.freepatentsonline.com Published On :: Tue, 21 Oct 2014 08:00:00 EDT The presently disclosed subject matter provides compositions that selectively bind cyclooxygenase-2 and comprise a therapeutic and/or diagnostic moiety. Also provided are methods for using the disclosed compositions for diagnosing (i.e., by imaging) a target cell and/or treating a disorder associated with a cyclooxygenase-2 biological activity. Full Article
po Light absorption anisotropic film, polarizing film, process for producing the polarizing film and display device using the polarizing film By www.freepatentsonline.com Published On :: Tue, 21 Oct 2014 08:00:00 EDT A light absorption anisotropic film, wherein content of a liquid crystalline non-colorable low molecular weight compound is 30% by mass or less; and which is obtained by fixing the alignment of a dichroic dye composition comprising at least one type of azo-based dichroic dye having nematic liquid crystallinity; and shows a diffraction peak derived from a periodic structure in a direction parallel to the alignment axis on measurement of X-ray diffraction. The light absorption anisotropic film is high in dichroism. Full Article
po (Amide amino alkane) metal compound, method of manufacturing metal-containing thin film using said metal compound By www.freepatentsonline.com Published On :: Tue, 28 Oct 2014 08:00:00 EDT The present invention relates to an (amide amino alkane) metal compound represented by the formula (1): wherein M represents a metal atom;R1 represents a linear, branched or cyclic alkyl group having 1 to 6 carbon atoms;R2 and R3 may be the same as, or different from each other, and each independently represents a linear or branched alkyl group having 1 to 3 carbon atoms, or R2 and R3 may form a substituted or unsubstituted 5- or 6-membered ring together with the nitrogen atom to which they are bound;Z represents a linear or branched alkylene group having 1 to 10 carbon atoms (a part of which may optionally form a ring); andn represents a number of the ligands, which is equal to the valence of the metal (M), and represents an integer of from 1 to 3; with the proviso that the metal compounds in which M is Li (Lithium), Be (Beryllium), Ge (Germanium) or Nd (Neodymium) are excluded;the metal compounds in which M is Mg (Magnesium) and R1 is methyl group are excluded;the metal compounds in which M is Zn (Zinc) and R1 is methyl group are excluded;the metal compounds in which M is Bi (Bismuth) and R1 is t-butyl group are excluded; andin cases where n is two or greater, two or more ligands may be the same as, or different from each other; and a method of producing a metal-containing thin film using the metal compound. Full Article
po Diaryl phosphine compounds By www.freepatentsonline.com Published On :: Tue, 28 Oct 2014 08:00:00 EDT A method for making diazo-compounds, diazonium salts thereof and other protected forms of these compounds. Diazo-compounds are prepared by reaction of a tertiary phosphine reagent carrying a reactive carbonyl group with an azide. The reaction can also generate an acyl triazene which can be converted thermally or by addition of base to form the diazo-compound or the acyl triazene can be isolated. The method is particularly useful for conversion of azides carrying one or more electron withdrawing groups to diazo-compounds. The method can be carried out in aqueous medium under mild conditions and is particularly useful for conversion of azido sugars to diazo-compounds and diazonium salts thereof under physiological conditions. Tertiary phosphine reagents, particularly those that are water-soluble, and precursors for preparation of the reagents are provided. Full Article
po Basic bisazo compounds By www.freepatentsonline.com Published On :: Tue, 30 Dec 2014 08:00:00 EST The invention relates to basic bisazo compounds according to formula (I) wherein all substituents are defined as in Claim 1, their production, their use as dyestuffs as well as material dyed with these dyestuffs. Full Article
po Dichroic dye composition, light absorption anisotropic film, and polarizing element By www.freepatentsonline.com Published On :: Tue, 06 Jan 2015 08:00:00 EST A light absorption anisotropic film, having at least one dichroic dye, in which the light absorption anisotropic film shows a diffraction peak derived from a periodic structure in a direction in a plane of the light absorption anisotropic film in X-ray diffraction measurement and the diffraction peak has a half width of 1.0 Å or less. Full Article
po Azo compound, ink composition, recording method and colored material By www.freepatentsonline.com Published On :: Tue, 13 Jan 2015 08:00:00 EST A coloring matter which exhibits excellent (ozone) gas resistance, high print density, low color rendering properties, low color saturation, and high-quality black hue when is recorded on a paper only for inkjet exclusive use, i.e., an azo compound represented by formula (1), a tautomer of the azo compound, or a salt of the azo compound or the tautomer; and an ink composition containing the coloring matter, particularly a black ink composition for inkjet recording applications. Full Article
po Process for preparing a polyester By www.freepatentsonline.com Published On :: Tue, 13 Jan 2015 08:00:00 EST Disclosed is a process for preparing a polyester or copolymer containing ester functionalities. The process can comprise: providing an optionally substituted lactone having a ring size of from 6 to 40 carbon atoms; andsubjecting said lactone to metal mediated ring-opening polymerization using as catalyst a compound according to general formula (I): wherein M can be Al, Cr, Mn and Co;X and X' are independently a heteroatom;Y and Y' can be, independently, selected from O, N, S, P, C, Si, and B;Z can be selected from hydrogen, borohydrides, aluminum hydrides, carbyls, silyls, hydroxide, alkoxides, aryloxides, carboxylates, carbonates, carbamates, amidos, thiolates, phosphides, and halides;L1 and L2 can be independently an organic ligand linking X and Y together and linking X' and Y' together, respectively; andL3 is an optional organic ligand linking Y and Y' together. Full Article
po Photo-responsive liquid crystalline compound and its applications By www.freepatentsonline.com Published On :: Tue, 13 Jan 2015 08:00:00 EST The purpose of the present invention is to provide novel liquid crystalline compounds that are capable of inducing phase transition by a light stimulus and are useful in the display, optoelectronics, and photonics field. The present invention relates to the liquid crystalline compounds represented by general formula (1): wherein R1, R2 and R3 are independently selected from the group consisting of hydrogen, alkyl, alkoxyl, alkoxycarbonyl, alkoxycarbonyloxy, alkanoyl, alkanoyloxy, alkoxyphenyl, and N-alkylaminocarbonyl, and n is an integer. Full Article
po Azo compound and dye polarizing film containing the same By www.freepatentsonline.com Published On :: Tue, 27 Jan 2015 08:00:00 EST Disclosed is an azo compound represented by the formula (1) below, a salt thereof, or a copper complex salt compound thereof. (In the formula, R1 and R2 independently represent a hydrogen atom, a sulfonic acid group, a lower alkyl group or a lower alkoxyl group; R3-R6 independently represent a hydrogen atom, a lower alkyl group or a lower alkoxyl group; R7 represents a lower alkyl group or a lower alkoxyl group; and n represents 0 or 1.) Full Article
po Azo compounds reducing formation and toxicity of amyloid beta aggregation intermediates By www.freepatentsonline.com Published On :: Tue, 10 Mar 2015 08:00:00 EDT The present invention relates to compounds suitable as modulators of protein misfolding and/or protein aggregation. The compounds are particularly suitable as inhibitors of amyloid aggregate formation and/or modulators of amyloid surface properties, and/or as activators of degradation or reduction of amyloid aggregates. Full Article
po Organometallic compositions and coating compositions By www.freepatentsonline.com Published On :: Tue, 14 Apr 2015 08:00:00 EDT The present invention is directed to novel organometallic complexes as catalysts for the reaction of compounds with isocyanate and hydroxyl functional groups to form urethane and/or polyurethane and the process employing such catalysts. More particularly, the present invention is directed to novel complexes of zinc(II) with substituted amidines. These novel catalysts are useful for the production of urethanes and polyurethanes which are important in many industrial applications. Full Article
po Liquid-crystal compound, liquid-crystal composition, light absorption anisotropic film, and liquid-crystal display device By www.freepatentsonline.com Published On :: Tue, 21 Apr 2015 08:00:00 EDT A liquid-crystal compound denoted by general formula (I) below wherein each of the groups is defined and Dye denotes an azo dye residue denoted by general formula (II) with X and n also being defined. The azo liquid-crystal compound is capable of orientation with a high degree of orientation order. Full Article
po Visible/near-infrared porphyrin-tape/C60 organic photodetectors By www.freepatentsonline.com Published On :: Tue, 28 Apr 2015 08:00:00 EDT Porphyrin compounds are provided. The compounds may further comprise a fused polycyclic aromatic hydrocarbon or a fused heterocyclic aromatic. Fused polycyclic aromatic hydrocarbon s and fused heterocyclic aromatics may extend and broaden absorption, and modify the solubility, crystallinity, and film-forming properties of the porphyrin compounds. Additionally, devices comprising porphyrin compounds are also provided. The porphyrin compounds may be used in a donor/acceptor configuration with compounds, such as C60. Full Article
po Azoquinone compound, electrophotographic photoconductor, and image forming apparatus By www.freepatentsonline.com Published On :: Tue, 05 May 2015 08:00:00 EDT The present disclosure relates to an azoquinone compound represented by formula (1) below. In formula (1), R1 to R4 are identical or different and each represents a hydrogen atom, a C1 to C6 alkyl group or a C6 to C12 aryl group, and Ar represents a C6 to C12 aryl group. Full Article
po Nitroimidazole-amino acid hypoxia contrast medium, preparation method and use thereof By www.freepatentsonline.com Published On :: Tue, 12 May 2015 08:00:00 EDT A hypoxia contrast medium including nitroimidazole-amino acid chelate with a positively charged radioactive nuclide, a preparation method and use thereof. The contrast medium can be used in imaging cerebral thrombosis, tumors or other diseases such as ulceration, thrombosis, and so on. Full Article
po Container and method for transporting a syringe containing radioactive material By www.freepatentsonline.com Published On :: Tue, 30 Jul 2002 08:00:00 EDT A method and apparatus for transporting syringes containing radioactive material. The apparatus includes a radiopharmaceutical pig having an inner chamber in which a sharps container can be secured. The sharps container has a housing and an attachable cap. The method includes assembling the radiopharmaceutical pig so that the chamber of the radiopharmaceutical pig contains the syringe in the sharps container housing. The radiopharmaceutical pig is disassembled, where upon the syringe is removed, discharged, and then replaced in the sharps container housing. The cap of the sharps container is affixed to the housing of the sharps container, thus enclosing the contaminated syringe therein. The radiopharmaceutical pig is assembled so that its chamber contains the sharps container and the syringe. The radiopharmaceutical pig is transported to a disposal area, where it is disassembled and the sharps container containing the syringe is placed in a particular disposal container. Full Article
po Radiopharmaceutical pig and transportation apparatus By www.freepatentsonline.com Published On :: Tue, 01 Jul 2003 08:00:00 EDT An apparatus and method for transporting radiopharmaceutical substances. The apparatus comprises a radiation shielding pig having an elongated sidewall that extends between two ends and that defines an elongated, interior chamber. The sidewall is thinner than each of the ends. A radiation shield defines at least one cavity. The shield has two open ends and a central area between the open ends that is thicker than each of the two open ends. Also, a method of assembling and disassembling the apparatus includes, placing a syringe filled with a radiopharmaceutical substance into the pig; placing the pig containing the filled syringe in the radiation shield; placing the pig and the shield into an ammunition can for transporting the radioactive substance contained in the syringe. Full Article
po Container transporting a syringe containing radioactive material By www.freepatentsonline.com Published On :: Tue, 20 Apr 2004 08:00:00 EDT A method and apparatus for transporting syringes containing radioactive material. The apparatus includes a radiopharmaceutical pig having an inner chamber in which a sharps container can be secured. The sharps container has a housing and an attachable cap. The method includes assembling the radiopharmaceutical pig so that the chamber of the radiopharmaceutical pig contains the syringe in the sharps container housing. The radiopharmaceutical pig is disassembled, where upon the syringe is removed, discharged, and then replaced in the sharps container housing. The cap of the sharps container is affixed to the housing of the sharps container, thus enclosing the contaminated syringe therein. The radiopharmaceutical pig is assembled so that its chamber contains the sharps container and the syringe. The radiopharmaceutical pig is transported to a disposal area, where it is disassembled and the sharps container containing the syringe is placed in a particular disposal container. Full Article
po Container and method for transporting a syringe containing radioactive material By www.freepatentsonline.com Published On :: Tue, 09 May 2006 08:00:00 EDT A method and apparatus for transporting syringes containing radioactive material. The apparatus includes a radiopharmaceutical pig having an inner chamber in which a sharps container can be secured. The sharps container has a housing and an attachable cap. The method includes assembling the radiopharmaceutical pig so that the chamber of the radiopharmaceutical pig contains the syringe in the sharps container housing. The radiopharmaceutical pig is disassembled, where upon the syringe is removed, discharged, and then replaced in the sharps container housing. The cap of the sharps container is affixed to the housing of the sharps container, thus enclosing the contaminated syringe therein. The radiopharmaceutical pig is assembled so that its chamber contains the sharps container and the syringe. The radiopharmaceutical pig is transported to a disposal area, where it is disassembled and the sharps container containing the syringe is placed in a particular disposal container. Full Article
po Container and method for transporting a syringe containing radioactive material By www.freepatentsonline.com Published On :: Tue, 08 Aug 2006 08:00:00 EDT A method and apparatus for transporting syringes containing radioactive material. The apparatus includes a radiopharmaceutical pig having an inner chamber in which a sharps container can be secured. The sharps container has a housing and an attachable cap. The method includes assembling the radiopharmaceutical pig so that the chamber of the radiopharmaceutical pig contains the syringe in the sharps container housing. The radiopharmaceutical pig is disassembled, where upon the syringe is removed, discharged, and then replaced in the sharps container housing. The cap of the sharps container is affixed to the housing of the sharps container, thus enclosing the contaminated syringe therein. The radiopharmaceutical pig is assembled so that its chamber contains the sharps container and the syringe. The radiopharmaceutical pig is transported to a disposal area, where it is disassembled and the sharps container containing the syringe is placed in a particular disposal container. Full Article
po Power source for re-circulation pump and method of controlling the same By www.freepatentsonline.com Published On :: Tue, 15 May 2007 08:00:00 EDT A variable-voltage variable-frequency power source for an electric motor that drives a re-circulation pump for a boiling water nuclear reactor. The power source has a semiconductor electric power converter and a speed controller for controlling the semiconductor electric power converter. When a part of the semiconductor electric power converter comes into an inoperative state, that part is electrically disconnected, and the variable-voltage variable-frequency power source temporarily stops outputting power, thereby idling the re-circulation pump. Thereafter, the power source re-starts outputting power before the re-circulation pump completely stops. Thus, the re-circulation pump keeps operating, without stopping. Full Article
po Power conversion circuitry By www.freepatentsonline.com Published On :: Tue, 26 Aug 2008 08:00:00 EDT One form of the invention is directed to an apparatus that comprises step-down circuitry to better match impedance between an input and an output that includes a number of stages each electrically coupled to another and each including a charge storage device. The circuitry further includes a number of switching devices operable in a first electrical connectivity state to connect the charge storage device of each of the stages in series to receive electrical charge from the input and in a second electrical connectivity state opposite the first state to connect the charge storage device of each of the stages in parallel to discharge electricity through the output. This circuitry can be used in connection with a radioisotopic conversion cell. Full Article
po Mixed-layered bismuth-oxygen-iodine materials for capture and waste disposal of radioactive iodine By www.freepatentsonline.com Published On :: Tue, 26 Feb 2013 08:00:00 EST Materials and methods of synthesizing mixed-layered bismuth oxy-iodine materials, which can be synthesized in the presence of aqueous radioactive iodine species found in caustic solutions (e.g. NaOH or KOH). This technology provides a one-step process for both iodine sequestration and storage from nuclear fuel cycles. It results in materials that will be durable for repository conditions much like those found in Waste Isolation Pilot Plant (WIPP) and estimated for Yucca Mountain (YMP). By controlled reactant concentrations, optimized compositions of these mixed-layered bismuth oxy-iodine inorganic materials are produced that have both a high iodine weight percentage and a low solubility in groundwater environments. Full Article
po Compositions and methods for treating nuclear fuel By www.freepatentsonline.com Published On :: Tue, 13 Aug 2013 08:00:00 EDT Compositions are provided that include nuclear fuel. Methods for treating nuclear fuel are provided which can include exposing the fuel to a carbonate-peroxide solution. Methods can also include exposing the fuel to an ammonium solution. Methods for acquiring molybdenum from a uranium comprising material are provided. Full Article
po Compositions and methods for treating nuclear fuel By www.freepatentsonline.com Published On :: Tue, 28 Jan 2014 08:00:00 EST Compositions are provided that include nuclear fuel. Methods for treating nuclear fuel are provided which can include exposing the fuel to a carbonate-peroxide solution. Methods can also include exposing the fuel to an ammonium solution. Methods for acquiring molybdenum from a uranium comprising material are provided. Full Article
po Polypeptides with permease activity By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT The invention relates to a polypeptide having a mutation at one or more position corresponding to T219 of SEQ ID NO: 55, wherein the polypeptide has at least 50% sequence identity with SEQ ID NO: 55, and wherein the polypeptide has permease activity. Full Article
po Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT Capture compounds and collections thereof and methods using the compounds for the analysis of biomolecules are provided. In particular, collections, compounds and methods are provided for analyzing complex protein mixtures, such as the proteome. The compounds are multifunctional reagents that provide for the separation and isolation of complex protein mixtures. Automated systems for performing the methods also are provided. Full Article
po Methods of using antibodies during anticoagulant therapy of dabigatran and/or related compounds By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT The present invention relates to antibody molecules against anticoagulants, in particular dabigatran, and their use as antidotes of such anticoagulants. Full Article
po Antioxidant, anti-inflammatory, anti-radiation, metal chelating compounds and uses thereof By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT Potent compounds having combined antioxidant, anti-inflammatory, anti-radiation and metal chelating properties are described. Short peptides having these properties, and methods and uses of such short peptides in clinical and cosmetic applications are described. Full Article
po Compounds that inhibit Hsp90 protein-protein interactions with IAP proteins By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT Disclosed herein are compounds that inhibit Hsp90 interactions with IAP proteins, such as Survivin, XIAP, cIAP1, or cIAP2, and methods for identifying and using such compounds. Full Article
po Temperature sensitive conjugate compositions By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT This disclosure relates to temperature sensitive conjugates, compositions, and uses related thereto. In certain embodiments, the disclosure relates to conjugate polymers comprising a) a temperature sensitive polymer and b) an antibody. Typically the antibody has an epitope to a platelet receptor. The antibody may be a single-chain antibody wherein the platelet receptor is GPIIb/IIIa, such as an anti-GPIIb/IIIa antibody. In certain embodiments, the antibody binds specifically to the activated conformation of GPIIb/IIIa, i.e., an activation-specific GPIIb/IIIa antibody. Full Article
po CX3CR1-binding polypeptides comprising immunoglobulin single variable domains By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT The present invention relates to CX3CR1-binding polypeptides, in particular polypeptides comprising specific immunoglobulin domains. The invention also relates to nucleic acids encoding such polypeptides; to methods for preparing such polypeptides; to host cells expressing or capable of expressing such polypeptides; to compositions comprising such polypeptides; and to uses of such polypeptides or such compositions, in particular for prophylactic, therapeutic and diagnostic purposes. Full Article
po Hypoallergenic molecules By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT The present invention relates to a hypoallergenic molecule consisting of Bet v Ia or an allergen having at least 40% identity to Bet v Ia comprising mutations of at least four amino acid residues in the region of amino acids 100 to 125 of Bet v Ia or its corresponding region of the allergen having at least 40% identity to Bet v 1a. Full Article
po Binding interaction of proanthocyanidins with bacteria and bacterial components By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A composition having proanthocyanidin compounds having an average degree of polymerization of at least about 6. A method of administering to an immunosuppressed patient or a patient diagnosed with sepsis or septic shock a composition having a proanthocyanidin. A method of administering to a patient diagnosed with a gram negative bacterial infection a composition having proanthocyanidin compounds having an average degree of polymerization of at least about 6. Full Article
po Cyclosporine emulsion By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT The present invention relates to a cyclosporine emulsion containing: i) a cyclosporine ii) a natural oil (long chain triglyceride) iii) a phosphatidylcholine, iv) glycerol, v) a pharmaceutically tolerable alkali salt of a free fatty acid, vi) a medium chain triglyceride-oil vii) optionally, hydrochloric acid or sodium hydroxide for pH adjustment viii) water. Full Article
po Support for affinity chromatography and method for isolating immunoglobulin By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT Provided are a support for affinity chromatography which has excellent alkali resistance, and a method for isolating immunoglobulin. A support for affinity chromatography, containing an immobilized protein ligand represented by the following formula (1): R—R2 (1) wherein R represents a polypeptide consisting of 4 to 30 amino acid residues that contains an amino acid sequence represented by ATK or ASK; and R2 represents a polypeptide consisting of 50 to 500 amino acid residues containing an immunoglobulin-binding domain consisting of an amino acid sequence represented by SEQ ID NO: 1 or SEQ ID NO: 2, the partial sequence thereof, or an amino acid sequence having 70% or more identity to these sequences; with the proviso that a terminus at which R2 binds to R is C-terminus or N-terminus of the immunoglobulin-binding domain. Full Article
po Methods and compositions comprising a C-terminal Bax peptide By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT In an aspect, the invention relates to compositions and methods for permeabilizing membranes of cells. In an aspect, the invention relates to compositions and methods for killing cells. In an aspect, the invention relates to compositions and methods of permeabilizing the membranes of cancer cells or microbial cells. Full Article