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Light-triggered dual-modality drug release of self-assembled prodrug-nanoparticles for synergistic photodynamic and hypoxia-activated therapy

Nanoscale Horiz., 2020, 5,886-894
DOI: 10.1039/D0NH00034E, Communication
Dongyang Zhao, Wenhui Tao, Songhao Li, Lingxiao Li, Yixin Sun, Guanting Li, Gang Wang, Yang Wang, Bin Lin, Cong Luo, Yongjun Wang, Maosheng Cheng, Zhonggui He, Jin Sun
Prodrug-nanoparticles turn the disadvantage of the aggregation-caused quenching effect into an advantage to promote dual-modality PR104A release. Besides, photodynamic therapy-induced hypoxia activates PR104A for high-efficiency synergistic therapy.
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Polished game development: from first steps to final release / Steven Goodwin

Online Resource




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Surprise release of Saints G Larry Warford puts 3-time Pro Bowler on open market

Opportunity knocks for teams in need of interior line help.




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Bears could make a move for recently-released Saints guard Larry Warford

One of the best guards of 2019 is all of a sudden on the market.




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Elon Musk delays release of Tesla's Roadster sports car

Tesla Inc Chief Executive Elon Musk said in a podcast interview released on Thursday that the company`s planned Roadster sports car would take a backseat to the development of other vehicle models.




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Citizenship Amendment Act Protest – Over 2000 ‘Gana Satyagrahi’ detained and released in Guwahati

More than 2000 ‘Gana Satyagrahi’ are detained for protesting against the ‘Citizenship Amendment Act’ in Assam’s capital city Guwahati today. As the protests against the unconstitutional ‘Citizenship Amendment Act’ continues, more than 2000 civic citizens were gathered on the bank of ‘Dighalipukhuri’ of Guwahati to assemble ‘Satyagraha’ today morning. The civic protesters included Assamese artists, […]

The post Citizenship Amendment Act Protest – Over 2000 ‘Gana Satyagrahi’ detained and released in Guwahati appeared first on TIMES OF ASSAM by Pradip Deka.




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Robert Fripp Releases Free Ambient Music to Get You Through the Lockdown: Enjoy “Music for Quiet Moments”

King Crimson’s master guitarist Robert Fripp has had a career long reputation as an autocrat, and exacting, difficult taskmaster. He’s named an album, a band, and a record company “Discipline.” Drummer Bill Bruford once described him as an “an amalgam of Stalin, Gandhi and the Marquis de Sade,” according to The Telegraph. But recently, there’s […]

Robert Fripp Releases Free Ambient Music to Get You Through the Lockdown: Enjoy “Music for Quiet Moments” is a post from: Open Culture. Follow us on Facebook, Twitter, and Google Plus, or get our Daily Email. And don't miss our big collections of Free Online Courses, Free Online Movies, Free eBooksFree Audio Books, Free Foreign Language Lessons, and MOOCs.





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[ASAP] Smart Glycopolymeric Nanoparticles for Multivalent Lectin Binding and Stimuli-Controlled Guest Release

Biomacromolecules
DOI: 10.1021/acs.biomac.0c00292




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'Pal Pal Dil Ke Paas' gets new release date

Actor-turned-politician Sunny Deol's son Karan's debut film "Pal Pal Dil Ke Paas" will now hit the screens on September 20 instead of its initial release date of July 19.




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Leave The Captial Released Today

New Title: Leave The Capital: A History of Manchester Music in 13 Recordings by Paul Hanley released today. The story of music that couldn’t have been made anywhere else but Manchester.




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Thro My Eyes Released Today

NEW TITLE: Thro' My Eyes: A Memoir by Iain Matthews, a story of music, journeys, life and what it does to us, through the eyes of one of our most enduring singer-songwriters.




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Its The Beer Talking Released Today

NEW TITLE: 'It's The Beer Talking' - Ian Clayton's memoir on a life of adventures in public houses takes us on a journey to the soul of the British pub. 'Brimming with laughter, tall stories, great memories and endless rounds of wonderful beer. It’s also a call to arms to save this unique institution.' - Roger Protz, Editor Good Beer Guide 2000-2018




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Sorry We Missed You Released Today

Official book for Ken Loach and Paul Laverty’s new film Sorry We Missed You released today.




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Have A Bleedin Guess Released Today

HAVE A BLEEDIN GUESS: The Story of Hex Enduction Hour by Paul Hanley goes on general release today, 38 years to the day since the release of the album.




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Take a walk to release your creative juices




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Biocatalytic reversible control of the stiffness of DNA-modified responsive hydrogels: applications in shape-memory, self-healing and autonomous controlled release of insulin

Chem. Sci., 2020, 11,4516-4524
DOI: 10.1039/D0SC01319F, Edge Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Chen Wang, Amit Fischer, Avner Ehrlich, Yaakov Nahmias, Itamar Willner
Biocatalytic control over the stiffness of pH-responsive hydrogels is applied to develop shape-memory, self-healing and controlled release matrices.
The content of this RSS Feed (c) The Royal Society of Chemistry




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A liquid biopsy-guided drug release system for cancer theranostics: integrating rapid circulating tumor cell detection and precision tumor therapy

Lab Chip, 2020, 20,1418-1425
DOI: 10.1039/D0LC00149J, Paper
Chun-Miao Xu, Man Tang, Jiao Feng, Hou-Fu Xia, Ling-Ling Wu, Dai-Wen Pang, Gang Chen, Zhi-Ling Zhang
A system integrating diagnostic and therapeutic functions for cancer is presented using magnetically controlled microfluidics.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Clip-to-release on amplification (CRoA): a novel DNA amplification enhancer on and off microfluidics

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00318B, Paper
Ren Shen, Yanwei Jia, Pui-In Mak, Rui P. Martins
A proposed DNA amplification enhancer with a “clip-to-release on amplification” mechanism reduces dye-mediated inhibition to amplification, increases fluorescence signal up to 10-fold, and eliminates false-negative results for on-chip PCR.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Online release: It’s film producers vs multiplexes

Multiplex players may boycott studios, actors if exclusive theatrical window not honoured




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AYUSH releases immunity-boosting measures for self-care during COVID-19 pandemic: Here is what you can do

The advisory was issued by the Ministry of AYUSH to support the efforts of all as a measure towards enhancing immunity.




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Maths formulae book released

Maths formulae book released




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Controlled release of entrapped nanoparticles from thermoresponsive hydrogels with tunable network characteristics

Soft Matter, 2020, Advance Article
DOI: 10.1039/D0SM00207K, Paper
Yi Wang, Zhen Li, Jie Ouyang, George Em Karniadakis
Thermoresponsive hydrogels have been studied intensively for creating smart drug carriers and controlled drug delivery.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Patna serial bomb blasts: Detained persons released in Ranchi, raids continue

Police recovered black powder, materials used to make IEDs and pressure cookers during the raids.




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As ethnic tensions rise over kidnapping of Mizos, Bru leaders send envoys to gain release

The MZP is planning a "Long March for Peace" from Aizawl to the western town of Tuipuibari.




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Apple, Google release coronavirus contact tracing APIs to select developers

The release is to encourage feedback that will help improve various features of the framework before the final rollout