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Educational Opportunities and Performance in West Virginia

This Quality Counts 2020 Highlights Report captures all the data you need to assess your state's performance on key educational outcomes.




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Educational Opportunities and Performance in Michigan

This Quality Counts 2020 Highlights Report captures all the data you need to assess your state's performance on key educational outcomes.




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Educational Opportunities and Performance in Illinois

This Quality Counts 2019 Highlights Report captures all the data you need to assess your state's performance on key educational outcomes.




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Educational Opportunities and Performance in Illinois

This Quality Counts 2020 Highlights Report captures all the data you need to assess your state's performance on key educational outcomes.




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Notre Dame WBB puts up highlight-reel performance in dominating Purdue

Dazzling first with a relentless hawking defense that helped force 22 turnovers, then adding an almost frantic-paced offensive assault, the 2-0 No. 6-ranked Irish overwhelmed Purdue (1-1), 102-58, at Mackey Arena in West Lafayette, Ind. Dynamo guard Hannah Hidalgo was slapping, diving and picking pockets all night, making life miserable for any Boilermaker stuck bringing the ball up the floor. ► Snap Counts: Here's who played for Notre Dame football against Florida St.




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Former Marquette women's basketball coach Carolyn Kieger accused of misconduct by ex-players

Onward State published a story this week that contained on-the-record comments from former Marquette players about Carolyn Kieger's coaching style.




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Lady Vols rely on best 3-point shooting performance of season to beat Middle Tennessee

Lady Vols basketball relied on its best 3-point shooting night of the season to close out a win over Middle Tennessee State on Tuesday




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Intraneuronal beta-Amyloid Aggregates, Neurodegeneration, and Neuron Loss in Transgenic Mice with Five Familial Alzheimer's Disease Mutations: Potential Factors in Amyloid Plaque Formation

Holly Oakley
Oct 4, 2006; 26:10129-10140
Neurobiology of Disease




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Stressed Memories: How Acute Stress Affects Memory Formation in Humans

Marloes J. A. G. Henckens
Aug 12, 2009; 29:10111-10119
BehavioralSystemsCognitive




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On Myelinated Axon Plasticity and Neuronal Circuit Formation and Function

Rafael G. Almeida
Oct 18, 2017; 37:10023-10034
Viewpoints




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Intraneuronal beta-Amyloid Aggregates, Neurodegeneration, and Neuron Loss in Transgenic Mice with Five Familial Alzheimer's Disease Mutations: Potential Factors in Amyloid Plaque Formation

Holly Oakley
Oct 4, 2006; 26:10129-10140
Neurobiology of Disease




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Recent Visual Experience Reshapes V4 Neuronal Activity and Improves Perceptual Performance

Recent visual experience heavily influences our visual perception, but how neuronal activity is reshaped to alter and improve perceptual discrimination remains unknown. We recorded from populations of neurons in visual cortical area V4 while two male rhesus macaque monkeys performed a natural image change detection task under different experience conditions. We found that maximizing the recent experience with a particular image led to an improvement in the ability to detect a change in that image. This improvement was associated with decreased neural responses to the image, consistent with neuronal changes previously seen in studies of adaptation and expectation. We found that the magnitude of behavioral improvement was correlated with the magnitude of response suppression. Furthermore, this suppression of activity led to an increase in signal separation, providing evidence that a reduction in activity can improve stimulus encoding. Within populations of neurons, greater recent experience was associated with decreased trial-to-trial shared variability, indicating that a reduction in variability is a key means by which experience influences perception. Taken together, the results of our study contribute to an understanding of how recent visual experience can shape our perception and behavior through modulating activity patterns in the mid-level visual cortex.




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TRIM46 Is Required for Microtubule Fasciculation In Vivo But Not Axon Specification or Axon Initial Segment Formation

Vertebrate nervous systems use the axon initial segment (AIS) to initiate action potentials and maintain neuronal polarity. The microtubule-associated protein tripartite motif containing 46 (TRIM46) was reported to regulate axon specification, AIS assembly, and neuronal polarity through the bundling, or fasciculation, of microtubules in the proximal axon. However, these claims are based on TRIM46 knockdown in cultured neurons. To investigate TRIM46 function in vivo, we examined male and female TRIM46 knock-out mice. Contrary to previous reports, we find that TRIM46 is dispensable for axon specification and AIS formation. TRIM46 knock-out mice are viable, have normal behavior, and have normal brain structure. Thus, TRIM46 is not required for AIS formation, axon specification, or nervous system function. However, we confirm that TRIM46 is required for microtubule fasciculation. We also show TRIM46 enrichment in the first ~100 μm of axon occurs independently of ankyrinG (AnkG) in vivo, although AnkG is required to restrict TRIM46 only to the AIS. Our results highlight the need for further investigation of the mechanisms by which the AIS and microtubules interact to shape neuronal structure and function.




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Anterior Olfactory Cortices Differentially Transform Bottom-Up Odor Signals to Produce Inverse Top-Down Outputs

Odor information arrives first in the main olfactory bulb and is then broadcasted to the olfactory cortices and striatum. Downstream regions have unique cellular and connectivity architectures that may generate different coding patterns to the same odors. To reveal region-specific response features, tuning and decoding of single-unit populations, we recorded responses to the same odors under the same conditions across regions, namely, the main olfactory bulb (MOB), the anterior olfactory nucleus (AON), the anterior piriform cortex (aPC), and the olfactory tubercle of the ventral striatum (OT), of awake male mice. We focused on chemically closely related aldehydes that still create distinct percepts. The MOB had the highest decoding accuracy for aldehydes and was the only region encoding chemical similarity. The MOB had the highest fraction of inhibited responses and narrowly tuned odor-excited responses in terms of timing and odor selectivity. Downstream, the interconnected AON and aPC differed in their response patterns to the same stimuli. While odor-excited responses dominated the AON, the aPC had a comparably high fraction of odor-inhibited responses. Both cortices share a main output target that is the MOB. This prompted us to test if the two regions convey also different net outputs. Aldehydes activated AON terminals in the MOB as a bulk signal but inhibited those from the aPC. The differential cortical projection responses generalized to complex odors. In summary, olfactory regions reveal specialized features in their encoding with AON and aPC differing in their local computations, thereby generating inverse net centrifugal and intercortical outputs.




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Spatiotemporal Neural Network for Sublexical Information Processing: An Intracranial SEEG Study

Words offer a unique opportunity to separate the processing mechanisms of object subcomponents from those of the whole object, because the phonological or semantic information provided by the word subcomponents (i.e., sublexical information) can conflict with that provided by the whole word (i.e., lexical information). Previous studies have revealed some of the specific brain regions and temporal information involved in sublexical information processing. However, a comprehensive spatiotemporal neural network for sublexical processing remains to be fully elucidated due to the low temporal or spatial resolutions of previous neuroimaging studies. In this study, we recorded stereoelectroencephalography signals with high spatial and temporal resolutions from a large sample of 39 epilepsy patients (both sexes) during a Chinese character oral reading task. We explored the activated brain regions and their connectivity related to three sublexical effects: phonological regularity (whether the whole character's pronunciation aligns with its phonetic radical), phonological consistency (whether characters with the same phonetic radical share the same pronunciation), and semantic transparency (whether the whole character's meaning aligns with its semantic radical). The results revealed that sublexical effects existed in the inferior frontal gyrus, precentral and postcentral gyri, temporal lobe, and middle occipital gyrus. Additionally, connectivity from the middle occipital gyrus to the postcentral gyrus and from postcentral gyrus to the fusiform gyrus was associated with the sublexical effects. These findings provide valuable insights into the spatiotemporal dynamics of sublexical processing and object recognition in the brain.




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FAO and Thomson Reuters Foundation to launch online food security information service

The Thomson Reuters Foundation, the corporate charity of the world’s biggest news and information providers, is teaming up with the UN Food and Agriculture Organization (FAO) to improve [...]




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Euro-Mediterranean Conference on Agriculture welcomes FAO transformational changes

Rome, 2 December 2014 – The Ministers of Agriculture of the European Union and of other Mediterranean countries welcomed FAO’s transformational changes implemented in the last two years, and underlined [...]




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FAO launches new South-South Cooperation Gateway: an information sharing platform

South-South Cooperation is the mutual sharing and exchange of development solutions - knowledge, experiences and good practices, policies, technology and resources - between and among countries in the global [...]




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Turning performance around

Published by the United Kingdom’s Department for International Development (DFID), the latest Multilateral Development Review describes FAO as a [...]




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Launch of The State of Food and Agriculture 2017 – Leveraging food systems for inclusive rural transformation

Since the 1990s, rural transformations have helped millions of people exit poverty while remaining in rural areas. This underscores an important fact: revitalising rural economies helps create jobs for rural [...]




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Informal Seminar: Human resources policies

Informal Seminar: Human resources policies - Invitation for all Permanent Representatives

 Friday, 12 October 2018 - 15.00 to 17.30 (Green Room)





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FAO titles in e-reader format – bringing knowledge to you

How do you prefer to read? On your phone, on your tablet, on your computer, or in print? And maybe the way you do it today is not the same [...]




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AMR Multi-Stakeholder Partnership Platform - Creating a movement for change through engaging multiple actors and voices

The Tripartite organizations (FAO, OIE, WHO) invite partners to join public discussion on the establishment of the AMR Multi-Stakeholder Partnership Platform.




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Transforming agrifood systems: from strategy to action

The Committee on Agriculture (COAG) is one of FAO’s Governing Bodies providing overall policy and regulatory guidance on issues relating to agriculture, livestock, food safety, nutrition, rural development and [...]




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FAO in Review: Leveraging partner strengths to transform agrifood systems

Read the series on how FAO increased efficiency, effectiveness and transparency to better support its Members in the transformation of agrifood systems.




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FAO in Review: Transforming agrifood systems in the face of the climate crisis

Read the series on how FAO increased efficiency, effectiveness and transparency to better support its Members in the transformation of agrifood systems.




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Information note - July 2023

The importance of Ukraine and the Russian Federation for global agricultural markets and the risks associated with the war in Ukraine. 




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FAO launches Global Information Exchange System under the 2009 Agreement on Port State Measures

Global exchange of information on compliance with national, regional, and international fisheries laws and regulations governing sustainable fishing is now possible with the launch of the Global [...]




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A transformative partnership

See how, together, the European Union and FAO are leveraging innovative approaches that benefit the global community




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The Hirshhorn Transforms for After Hours

Art and music lovers who attended the museum's premier event were treated to Andy Warhol's "Shadows" and live music




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Performing Ask Your Mama

In a workshop at the University of Michigan, composer Laura Karpman oversees a rehearsal of Ask Your Mama, a musical rendition of the Langston Hughes epic poem, with George Manahan conducting




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American History Museum Transformed

A step-by-step tour of the renovation of the National Museum of American History (Narration by Beth Py-Lieberman / Edited by Ryan Reed and Brian Wolly)




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Former Poet Laureate Billy Collins Reads "The Unfortunate Traveler"

Smithsonian magazine's poetry consultant recites his poem commissioned for a special photography issue




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A Former Afghan Interpreter for the U.S. Military Recalls the Dangers of the Job

(Footage: Erin Trieb. Video Editing: Nicole Boliaux)




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Civil War (Joan Baez), With Dance Performance By Djassi Johnson and Kevin Boseman

Part of the visual album of Joan Baez' "Whistle Down the Wind," this cover of Joe Henry's "Civil War" was directed by New York University's Deborah Willis




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How Water Beads Form

Duke University scientists used vibrations from a loudspeaker to understand how water beads and rolls off lotus leaves




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Buzz Aldrin and Thomas Dolby Perform "She Blinded Me With Science"

Some of the brightest minds in the world gathered at Smithsonian's "The Future is Here" conference to discuss the great triumphs and future innovations in science and technology http://www.smithsonianmag.com/ideas-innovations/The-Future-is-Here.html




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Hazel Scott, Jazz and Classical Pianist, Performs Liszt

Read more at http://www.smithsonianmag.com/arts-culture/Hazel-Scotts-Lifetime-of-High-Notes.html In a performance filmed for World War II soldiers, Hazel Scott begins with a section from Liszt's "Hungarian Rhapsody No. 2" and ends with a jazzy tune (Army / Navy Screen Magazine).




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See the Vatican's Magnificent Marble Statue of the Greek God Apollo Restored to Its Former Glory

Experts added a carbon fiber pole to help anchor the "Apollo Belvedere," which had developed cracks along the legs and knees. Now, the looming Roman sculpture is finally back on display




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Biden Issues a 'Long Overdue' Formal Apology for Native American Boarding Schools

The president atoned for the federal government's role in forcing Native American children into boarding schools, where many were abused and more than 900 died




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Banksy's Former Manager Sells His Trove of Artworks and Other Objects Connected to the Anonymous Street Artist

Steve Lazarides' personal collection of prints, original works, handwritten press releases and burner phones sold at auction for around $1.4 million




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Former mayor accused of property encroachment violations in Dawson City files his defence against town

Former Dawson City Mayor Bill Kendrick has filed his defence against the town's encroachment violation lawsuit.



  • News/Canada/North

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RCMP ask for information, photos of Xavia Butler to fill in timeline before she was found

Over the weekend, RCMP says officers searched for answers in the death of the toddler, knocking door-to-door on Saturday in Ashern and the surrounding communities of Gypsumville as they canvassed for information that may shed light on the timeline surrounding the child's death.



  • News/Canada/Manitoba

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Doctor pushes back on medical misinformation

CBC Winnipeg News host Brittany Greenslade speaks with Canadian gynecologist Dr. Jen Gunter, who is part of a Tuesday panel discussion about health misinformation and how to separate fact from fiction. It's part of Together Against Misinformation Week, a nationwide event that runs until Nov. 17.




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8-year-old Sammy Wong to perform with K-W Symphony musicians

Sammy Wong, 8, of Waterloo has been playing the violin since he was 5 years old. He has been rehearsing for an upcoming concert with the musicians of the K-W Symphony on Saturday night at the Registry Theatre in Kitchener. The show, titled Prodigio del Violino:An Evening with Sammy Wong, will feature the music of Mozart and Vivaldi.




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Apology long overdue for U.S. Indian boarding schools, says former student

A former student of federal Indian boarding schools in the U.S. says Joe Biden's rare presidential apology was long overdue. "They should have done it years ago," says 74-year-old Rosie Yellowhair.




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Ontario Liberals announce tax cuts for middle class families as part of election platform

The Ontario Liberal Party is pledging to reduce the income tax rate for middle class families and eliminate provincial sales tax on hydro bills, if they win in the 2026 election.



  • News/Canada/Toronto

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Mosquito Egg Development and Eggshell Formation

Anautogenous female mosquitoes, which ingest a blood meal from warm-blooded vertebrates to produce eggs, have become a valuable model organism for investigating signaling pathways and physiological processes that occur during egg development. Different molecular pathways tightly regulate the initiation of egg development and are governed by a balance among different insect hormones. Gravid (mature egg-carrying) females deposit fully developed eggs at the end of each gonotrophic cycle, which is defined as the time interval between the ingestion of a blood meal to oviposition. An intact eggshell protects the oocyte and embryo inside from external factors such as desiccation, physical damage, etc., and the various eggshell proteins are spatially and temporary deposited during oogenesis. Additionally, follicle resorption (oosorption) during blood meal–induced mosquito ovarian follicle development is an adapted physiological process that optimizes reproductive fitness. Mosquito oocytes grow and mature synchronously throughout oogenesis; however, during the later stages of oogenesis, some oocytes may undergo oosorption if sufficient nutrients are unavailable. This introduction highlights how mosquito egg development can be used to investigate follicular resorption and identify proteins involved in eggshell formation in Aedes aegypti mosquitoes.




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DS SolidWorks Education Edition 2009 Expands Access To Advanced CAD Functionality While Boosting Performance

New Licensing, Support Programs For Certification Accompany Software Upgrades




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SolidWorks Software Helps Transform Bathroom into Design-Inspired Retreat

With SolidWorks Enterprise PDM Software, DECOLAV Accelerates and Coordinates Global Design of Luxury Bathrooms