The present invention includes a device comprising a lid and a vessel forming an interface that allows transfer of waste from a purification chamber to a waste chamber and method for purification of an analyte are disclosed wherein a supernatant is separated from a solid phase to which an analyte is bound by centrifugation via the lid of the device. The present invention also includes methods for use of the device.

A device for capturing a three-dimensional object is presented, which allows, on one hand, a sufficiently large number of projected pixels and a high image quality of the projected pixels, and which has, on the other hand, a compact size and low assembly costs.

The invention refers to a device for recording biometric data, such as lines of finger or hand. A rest is provided on the device for the hand and finger, respectively, as well as an illuminating unit. According to the invention an illuminating unit and/or rest is provided that can traverse and be positioned.

A 3D image sensor includes a depth pixel that includes; a photo detector generating photo-charge, first and second floating diffusion regions, a first transfer transistor transferring photo-charge to the first floating diffusion region during a first transfer period in response to a first transfer gate signal, a second transfer transistor transferring photo-charge to the second floating diffusion region during a second transfer period in response to a second transfer gate signal, and an overflow transistor that discharges surplus photo-charge in response to a drive gate signal. Control logic unit controlling operation of the depth pixel includes a first logic element providing the first transfer gate signal, a second logic element providing the second transfer gate signal, and another logic element providing the drive gate signal to the overflow transistor when the first transfer period overlaps, at least in part, the second transfer period.

A portable, tabletop fluid sampling device simplifies spectral analysis to produce an accurate but inexpensive chromatic fingerprint for fluid samples. In one embodiment, the sampling device uses an array of variable wavelength LED emitters and photodiode detectors to measure Rayleigh scattering of electromagnetic energy from the fluid sample contained in a cuvette. Either the fluid itself, or particles suspended in the fluid can then be identified by performing spectral pattern matching to compare results of a spectral scan against a library of known spectra. A wide range of applications include substance identification, security screening, authentication, quality control, and medical diagnostics.

A defect inspection device has: an illumination optical system which irradiates a predetermined region of an inspection target with illumination light; a detection optical system which has a detector provided with a plurality of pixels by which scattered light from the predetermined region of the inspection target due to illumination light from the illumination optical system can be detected; and a signal processing portion which is provided with a correction portion which corrects pixel displacement caused by change in a direction perpendicular to a surface of the inspection target with respect to a detection signal based on the scattered light detected by the detector of the detection optical system, and a defect determination portion which determines a defect on the surface of the inspection target based on the detection signal corrected by the correction portion.

Spectroscopy apparatuses oriented to the critical angle of the sample are described that detecting the spectral characteristics of a sample wherein the apparatus consists of an electromagnetic radiation source adapted to excite a sample with electromagnetic radiation introduced to the sample at a location at an angle of incidence at or near a critical angle of the sample; a transmitting crystal in communication with the electromagnetic radiation source and the sample, the transmitting crystal having a high refractive index adapted to reflect the electromagnetic radiation internally; a reflector adapted to introduce the electromagnetic radiation to the sample at or near an angle of incidence near the critical angle between the transmitting crystal and sample; and a detector for detecting the electromagnetic radiation from the sample. Also, provided herein are methods, systems, and kits incorporating the peri-critical reflection spectroscopy apparatus.

An estimation device is configured to estimate a feature value of a specific component contained in a sample and includes: a spectral estimation parameter storage module; a calibration parameter storage module; a multiband image acquirer; an optical spectrum operator configured to compute an optical spectrum from a multiband image using a spectral estimation parameter; and a calibration processor configured to compute the feature value from the optical spectrum using a calibration parameter.

An apparatus for securing a diagnostic tool proximate to and in front of a display device between the corners thereof. A harness is adapted to releasably hold the diagnostic tool, a restraining bracket extends from the harness, and there is at least one elastic cord having a first end, an intermediate portion and a second end. The cord is threaded through the restraining bracket and is sized so as to impart elastic tension to the corners of the display device while concomitantly protecting the front surface from pressure due to the position of the harness and diagnostic tool.

Techniques and devices for measuring polarization crosstalk in birefringence optical media including polarization maintaining fiber.

[Problem to be Solved] To improve the measurement accuracy of an interference measurement device which utilizes interference of light. [Means for Solution] An interference measurement device includes a light source 10 for emitting supercontinuum light (SC light), an optical fiber coupler 11 for splitting the SC light into measurement light and reference light, a dispersion compensation element 12, a drive unit 13 for moving the dispersion compensation element 12, and light-receiving means 14 for measuring an interference waveform produced as a result of interference between the measurement light and the reference light. A measurement object 15 to be measured is an Si substrate having a thickness of 800 μm. The dispersion compensation element 12 is an Si substrate having a thickness of 780 μm. Namely, the dispersion compensation element 12 is formed of the same material as that of the measurement object 15 and is 20 μm thinner than the measurement object 15. The interference caused by reflection on the back surface of the measurement object 15 and reflection on the back surface of the dispersion compensation element 12 has a narrow peak width because wavelength dispersion is cancelled almost completely. Thus, the accuracy in measuring the peak position improves. As a result, the accuracy in measuring temperature, etc., improves.

An optical electrical field enhancing device includes: a transparent substrate having a structure of fine protrusions and recesses on the surface thereof; and a metal structure layer of fine protrusions and recesses formed on the surface of the structure of fine protrusions and recesses. The metal structure layer of fine protrusions and recesses has a structure of fine protrusions and recesses, in which the distances among adjacent protrusions are less than the distances among corresponding adjacent protrusions of the structure of fine protrusions and recesses of the transparent substrate.

A binding device includes binding rod portions, coupling portions for coupling a plurality of the binding rod portions, and an axis portion serving as a center upon opening/closing of binding rods. The coupling portions have lower portions to which the axis portion is provided at a position close to base portions of the binding rods so that a leaf bound at the binding rod portions can be flipped along the binding rods and flipped through 360 degrees and leaves can make contact with each other with the axis portion sandwiched therebetween. The axis portion includes a shaft portion and receiving portions for the shaft portion. The receiving portions are provided to the coupling portions the shaft portion is disposed therein.

A binding device includes a plurality of binding rings, a holding member which enables the binding rings to be disposed with a spacing therebetween, an operating member having a surface to which base portions of the binding rings are secured such that the binding rings are disposed with a spacing therebetween, the operating member including a pair of operating pieces movable in the holding member in a longitudinal direction of the holding member, and an opening-closing member which causes the binding rings to be changed in an opening direction. The opening-closing member includes an elastic member. The elastic member is provided in the operating member such that a distance between the operating pieces in an opening-closing direction of the binding rings is maintained at a distance enabling the pair of the operating pieces to be moved and is arranged to move the pair of the operating pieces defining the operating member relative to each other in respective opposite directions and so as to elastically urge the pair of the operating pieces in a direction allowing the binding rings to be held in an opened state.

A scrapbooking page alignment device for temporarily aligning at least two adjacent scrapbook pages having retention receivers extending from their respective spine edges, the device comprising (i) a base; and (ii) two or more spaced retention posts extending from said base; where said retention posts are dimensioned to temporarily receive the retention receivers of the two adjacent scrapbook pages.

A binding device is provided which allows reduction in profile. A binding device 10 includes: a holding member 16 having a length which allows a plurality of openable-closable binding rings 12 and 14 to be disposed with a spacing therebetween; an operating member 18 secured inside the holding member 16; and an opening/closing member 40. The operating member 18 includes a pair of operating pieces 30 and 32 on which the binding rings 12 and 14 are secured. For housing the opening/closing member 40, an opening/closing member housing portion 36 is provided in a manner such as to be recessed from a reverse side, opposite to a surface on which the binding rings 12 and 14 are secured, towards the surface side. The opening/closing member 40 is secured to the opening/closing member housing portion 36 of the operating member 18 on the reverse side opposite to the surface on which the binding rings 12 and 14 are secured, and is formed to, when the binding rings 12 and 14 are opened, cause the binding rings 12 and 14 to be changed in an opening direction so that the operating pieces are moved in a longitudinal direction of the holding member 16 and are held in a direction approaching an inner surface of the holding member 16, within the holding member 16.

An additional electric power receiving method replacing conventional grounding with a negative voltage source includes the step of transmitting electromagnetic wave or current from a power supply source to a rectifier, wherein a grounding end of the rectifier is in electrical communication with the negative voltage source, and the negative voltage source is selected from a negative potential intrinsic of an organism. A device applicable to the electric power receiving method includes a rectifier having an input end and two output ends, wherein the input end is in electrical communication with a power supply source, and rectified direct current is transmitted from the output ends. With the method and device, not only an increase in additional electric power obtained is achieved, but conversion efficiency and stability of current and electromagnetic wave is enhanced.

A power supply can provide brown-out protection and overheat protection. The power supply includes a rectifier, a transformer, and a power management device. The rectifier is used for receiving an alternating current voltage. The alternating current voltage has a voltage cycle. The transformer coupled to the rectifier has an inductor coupled to a switch for supplying an output voltage. The power management device is used for controlling the switch to make the inductor save power or release power. The power management device has a multi-functional pin coupled to the rectifier for receiving a detection voltage corresponding to a positive half cycle of the alternating current voltage. The multi-functional pin is also coupled to a thermistor for receiving an overheat protection signal.

A semiconductor device of a three-level inverter circuit with a reduced number of power supplies for driving IGBTs. The semiconductor device includes a series-connected circuit of IGBTs between P and N of a DC power supply and an AC switch element that is connected between a series connection point of the series-connected circuit and a neutral point of the DC power supply. The series-connected circuit and the AC switch element are integrated into one module. The AC switch element is formed by connecting a collector of a first IGBT to which a diode is connected in reverse parallel and a collector of a second IGBT to which a diode is connected in reverse parallel, and an intermediate terminal is provided at a connection point between the collectors.

Embodiments provide a magnetic flux conversion device (MFCD) that may produce a regulated output signal with a target value (e.g., target voltage and/or target current) from a source signal on a power line. The MFCD may include a secondary stage configured to be inductively coupled with the power line. The source signal may cause a secondary electrical signal to flow in the secondary stage. A regulator module may be coupled to the secondary stage and configured to produce the output signal with the target value across output nodes by sensing the output signal and shunting the secondary stage if a value of the output signal is above the target value.

An optical head device (11) provided with: an optical element (36) for transmissively diffracting a light beam emitted from a semiconductor laser (34), generating a zero-order diffracted light beam and ±1-order diffracted light beams; and a photodetector (40) for receiving the zero-order diffracted light beam and the +1-order diffracted light beam after reflection from an optical disc (2). The photodetector (40) includes a primary light receiving section (400) for receiving the zero-order diffracted light beam, and a first secondary light receiving section (401) disposed outward from the primary light receiving section (400). The first secondary light receiving section (401) is positioned to detect an outer portion of the received light spot of the +1-order diffracted light beam, performs photoelectric conversion of this portion, and outputs a secondary detected signal.

Provided are an optical pickup device and an optical disk drive including the same. The optical pickup device includes a quarter-wave plate (QWP) that is disposed parallel to an objective lens and a reflection mirror that reflects a beam back onto the QWP after the beam passed through the QWP. The optical pickup device also includes a polarization mirror that is disposed between the objective lens and the QWP, and which reflects the beam which is generated from a light source onto the QWP, and allows the beam reflected by the reflection mirror to pass through to the objective lens.

A recording head for recording information on a rotating recording medium of a storage device includes a main magnetic pole which generates a recording magnetic field in a direction perpendicular to a recording medium facing surface of the magnetic recording head, and a light generating element which is provided on a leading side of the main magnetic pole, and generates light for heating the recording layer of the recording medium. The main magnetic pole includes an end surface facing the light generating element that is inclined with respect to the direction perpendicular to the recording medium facing surface toward the light generating element.

An optical disk device includes an optical pickup that directs light beams onto a recording surface of an optical disk and receives reflected light, a signal generating unit that generates playback signals based on reflected light received by the optical pickup, an equalizer adjustment unit that performs equalizer adjustment of the playback signals, and an adjustment control unit. The adjustment control unit controls the equalizer adjustment unit so as to perform equalizer adjustment of the playback signals according to the playback signals based on reflected light from a management information area on a recording surface of the optical disk, the management information area including predetermined management information recorded thereon.

Disclosed is an optical information recording and reproducing device capable of recording an interference fringe pattern as a hologram in an optical information recording medium, the interference fringe pattern being formed by a signal beam superimposed with signal information and a reference beam, and also capable of reproducing the signal information from the optical information recording medium, the device having a light source unit to emit light, a light splitting unit to split the light into the reference beam and the signal beam, a spatial light modulation unit to superimpose the signal information on the signal light, and a light detection unit to detect an image reproduced by the reference beam, wherein information about defects on the spatial light modulation unit is recorded in the optical information recording medium.

A wireless media player and a related system and methodology are disclosed. One aspect of the wireless media player system pertains to a virtual connector system, apparatus, and method for the automatic establishment of wireless connectivity with other electronic devices. In one embodiment, the media player device employs the use of integrated Radio Frequency Identification (RFID) technology to exchange communication settings, media capability, and other parameters with an external device that also has integrated RFID technology. The automatic exchange of settings and other information via a proximity-based RFID data exchange allows a media player to quickly establish a secure communication link with another device via a commonly supported wireless protocol such as Ultra Wideband (UWB) or Bluetooth. Another aspect of the media player system pertains to a method of using the captured media capability of the connecting device to customize certain menu options and software parameters in the media player.

An apparatus includes a write element configured to apply a magnetic field to write data on a portion of a heat-assisted magnetic recording media in response to an energizing current. An energy source is configured to heat the portion of the media being magnetized by the write element. A preheat energizing current is applied to the write element during an interval before writing the data to the portion of the media. The preheat energizing current does not cause data to be written to the media and brings at least one of the write element and driver circuitry into thermal equilibrium prior to writing the data on the portion.

According to one embodiment, a multilayer optical recording medium including a substrate, a guide layer group that is provided on the substrate and has guide layers in which positional information in a radial direction is recorded, and a recording layer group that is provided on the substrate and has recording layers in which information can be recorded. In the recording layer group, positional information of the recording layers associated with the positional information recorded in the guide layers and control information of the optical device where reflected light volumes of the laser beams on the guide layers and the recording layers become maximum at the positions in the radial direction are recorded at the positions in the radial direction of the recording layers.

A wireless media player and a related system and methodology are disclosed. One aspect of the wireless media player system pertains to a virtual connector system, apparatus, and method for the automatic establishment of wireless connectivity with other electronic devices. In one embodiment, the media player device employs the use of integrated Radio Frequency Identification (RFID) technology to exchange communication settings, media capability, and other parameters with an external device that also has integrated RFID technology. The automatic exchange of settings and other information via a proximity-based RFID data exchange allows a media player to quickly establish a secure communication link with another device via a commonly supported wireless protocol such as Ultra Wideband (UWB) or Bluetooth. Another aspect of the media player system pertains to a method of using the captured media capability of the connecting device to customize certain menu options and software parameters in the media player.

A data storage device is disclosed comprising a head actuated over a disk, wherein the head comprises a laser configured to heat the disk while writing data to the disk. A temperature is measured, and a first input power is generated based on a first function of the measured temperature, wherein the first function compensates for a temperature dependent output power of the laser. A second input power is generated based on a second function of the measured temperature, wherein the second function compensates for a temperature dependent coercivity of the disk. The first input power is combined with the second input power to generate a write power applied to the laser while writing data to the disk.

In an optical information recording device and optical information recording method for angularly multiplexing and recording data on pages on the same recording region on a hologram disk, data on each page is sequentially generated by sequentially dividing input data in predetermined units, the pages to be recorded on the same recording region are divided into page groups so that pages to be recorded adjacently by the angular multiplexing may not belong to the same group, each page group is individually subjected to inter-page coding processing for computing an error-correcting code and adding the computed error-correcting code, and data on the pages subjected to the inter-page coding processing is angularly multiplexed and recorded on the hologram disk.

An near-field light device (100) is provided with: a first electrode layer (123) having a protruding portion (123a); a second electrode layer (121); and a light emitting layer (122), the protruding portion protrudes along a predetermined direction (Y axis direction) to be capable of extracting energy which is caused by emission of light at the light emitting layer, the predetermined direction intersects with a laminated direction (X axis direction) of the near-field light device, an edge surface of at least one portion of the projection portion is located at more outward side in the optical device than an edge surface of the second electrode layer is.

Orthopedic devices, systems, and methods of using the same are disclosed. In an embodiment, an orthopedic device intended for use with at least one moveable body part of a user may comprise a tubular body forming an interior surface and an exterior surface. The tubular body may include at least one opening and one or more shrinkable materials. The tubular body may be moveable between a first position, wherein the tubular body is configured to at least partially receive and at least partially surround the at least one moveable body part of the user, and a second position, wherein one or more portions of the tubular body are configured to generally conform to and at least partially restrict movement of the at least one moveable body part in one or more directions. The tubular body may be configured to move from the first position to the second position in response to a treatment.

This application presents retention devices that afford the user quick and easy placement. These retention devices may accommodate objects of various shapes and sizes. The device provides sturdy means for retaining and securing an object to a surface without the need to handle and position flaps of tape. The device allows easy removal from the retained object without adhesives directly contacting or damaging it sensitive surfaces. The retention described here may be used to quickly secure anatomic structures during operations, such as securing the penis against the abdomen during vasectomy, without causing discomfort or damage to sensitive skin during application or removal.

A custom brace and method for fabricating the custom brace includes marking a body with reference points and/or other indicators. Multiple images of the body from multiple angles are then obtained. The images are used to determine the contours of the body and the other markings are located and used to design the custom brace. Fenestrations can be added to the brace design. The custom brace can be fabricated with the fenestrations as a single piece structure or in multiple pieces that are assembled to complete the custom device.

A bandage and method for securing a tension member comprising a central body and a plurality of tabs disposed about the central body. A tension member may be disposed across or through a slit or aperture of the central body. A body adhesive on the lower surface of the central body may secure the bandage to the patient. The tension member may then be pulled across the upper surface of the central body and a first tab may be folded over and adhered to the tension member and central body. The tension member may then be pulled back across the first tab and a second tab may be folded over and adhered to the tension member and first tab. Likewise, the tension member may then be pulled back across the second tab and a third tab may be folded over and adhered to the tension member and second tab.

An orthopedic device for correcting abnormalities in the wrist, hand, fingers and thumb of a newborn baby comprises a lightweight glove shaped semi rigid shell constructed and dimensioned to fit a newborn baby within a few hours of birth. A wrist or lower arm and hand engaging portion are rotatably connected and adjustable in one millimeter increments. The adjustments are made with no more than one millimeter correction per 24 hour period. The shell includes a wrist and lower forearm engaging portion, a hand engaging portion and a finger engaging portion and is adjustable for rotationally clockwise or counterclockwise about the longitudinal axis of the lower arm bone. Further adjustments may be made to rotate the fingers upwardly or downwardly, to the left or right and rotationally and/or rotational movement between the hand and lower arm. The invention also contemplates an orthopedic method for correcting skeletal abnormalities of the wrist, hand, fingers and thumb of a newborn baby.

A wound treatment device comprises a wound surface contacting plug and a cover for covering the wound surface and the plug, wherein said plug consists of a flat textile isolating material comprising at least one first surface layer, one second surface layer and one intermediate space arranged between said surface layers. At least the first surface layer is provided with a biocompatible surface and a structure which enables a liquid to pass and prevents a wound tissue from growing in said structure. The intermediate space is provided with isolating threads elastically holding the first surface layer and the second surface layer at a certain distance from each other.

An orthopedic device has a main body panel including a longitudinal length with a curved cross-section, and opposed lateral and medial sides. A posterior panel is secured to the lateral and medial sides of the main body panel, and is sized longitudinally shorter than the main body panel in a non-stretched condition. The posterior panel is secured to the main body panel in a pretensioned condition and spans the longitudinal length of the main body panel along the lateral and medial sides thereof.

In a walking assistance device (10) that can transmit the power generated by a power generator (26, 28) to a femoral part of a user, a swing arm (60, 62) is attached to an output member of the power generator at a base end thereof, and is connected to a femoral support plate (68, 70) at a free end thereof via a pivot joint (64). The pivot joint includes a spherical projection (100) provided on the free end of the swing arm and a socket (112) provided on the femoral support plate, the socket defining a spherical recess (110) configured to receive the spherical projection to permit a tilting movement of the femoral support plate at least in two directions with respect to the free end of the swing arm. Thereby, the femoral support plate is enabled to accommodate the build and/or the movement of the femoral part of the user.

A junctional and truncal tourniquet and a hip-girdling pelvic sling device for maintaining a desired amount of tension surrounding a person's hips and pelvis to securely support and stabilize a pelvis that has been fractured and for securing a pressure applying device to a person so that blood vessel-occluding pressure can be applied. Areas of mating types of fastener material such as mating hook-bearing fastener material and loop pile fastener material are arranged on the device to enable a strap to be secured at various effective lengths to provide a wide range of adjustability. The device may include inflatable bladders, stays, and a chin support and may be wrapped around a patient's neck as a cervical support collar, or around the torso to occlude blood vessels proximal to an injury on a limb.

The invention relates to a fixing element (33) extending as a flat, particularly lamellar element along a preferred direction (34) and comprising a corrugated sheet metal core (18) as a central component, said core providing the fixing element (33) with the characteristic of being integrally rigid and permanently deformable by hand, and said core being covered by a cover (36, 37). For such a fixing element, a large range of use is achieved in that the corrugations of the corrugated core sheet (18) are oriented substantially parallel to the preferred direction (34), and that means (38, 39) for releasably attaching the fixing element (33) are disposed on the fixing element (33).

Orthopedic device for treating neuropathic ulcers and other injuries while allowing easy access to the wound site on the plantar surface of a patient's foot includes a base portion and a sole that is either movably connected or removably connected to either the base or to a strut member. The base or strut is maintained in position on the lower leg while the sole may be rotated, slid, or completely removed for allowing inspection and access to the plantar surface of the patient's foot.

A hammer toe treatment device to help uncurl a hammer toe and protect the toe including a base pad configured to extend in a neck portion of the between the toe mound and tip of the toe. The base pad including an arcuate top surface extending in the direction of the hammer toe and configured to produce a straightening force against the toe. The pad including a bottom surface generally opposite to the top surface that includes a generally flat surface configured to engage a shoe insole when the shoe is worn. The base pad further including a tubular toe sleeve fixed relative to the base pad and extending forwardly along a sleeve axis from a reward toe opening. The sleeve axis extending at a sleeve angle relative to the bottom surface and the sleeve being shaped to receive the hammer toe and cover a substantial portion of the toe.

A polyester resin is a polycondensate obtained by reacting a divalent alcohol, a divalent carboxylic acid, and a mono- or divalent rosin by the use of a zinc compound as a reaction catalyst.

Devices and methods for gastrointestinal bypass are described. A gastrointestinal bypass device includes a gastrointestinal cuff and a gastrointestinal sleeve. The cuff may be configured to be attached in the esophagus, and may be sufficiently flexible to expand and collapse to conform with the inside of the esophagus to allow the esophagus to function substantially normally. The sleeve is configured to be coupled to the cuff, and may be made of a material that is floppy or flaccid but does not substantially expand radially.

A method for securing an implantable medical device onto a balloon which includes applying a coating, which includes a film-forming polymer and at least one solvent, to the outer surface of the balloon. The solvents can include alcohol, water, ether and combinations thereof. The film-forming polymer can include a zwitterionic polymer, such as, for example a phosphorylcholine polymer. The coating can be applied to the entire balloon surface or a portion of the surface. The implantable medical device is then positioned on the outer surface of the balloon and secured. The film-forming polymer is then allowed to cure in order to define an adhesive layer between an inner surface of the implantable medical device and the outer surface of the balloon. This method prevents or reduces the leaching or redistribution of any therapeutic agents dispersed within or on the surface of the implantable medical device.

A device and method for delivering a vascular device to a target site is provided that maintains a proximal portion of the vascular device within a tubular sleeve by positioning a stop of an inner member at a distal opening of the tubular sleeve to block the opening. Once the stop has been moved distally via movement of the inner member to clear the opening, a band of increased thickness on the inner member can urge the proximal portion of the vascular device out of the tubular sleeve to deploy the vascular device. The vascular device may be recaptured within a delivery sheath prior to the full deployment of the proximal portion of the vascular device from the tubular sleeve by re-positioning the stop at the distal opening to hold the vascular device within the tubular sleeve as the delivery device is retracted with respect to the delivery sheath.

An implantable device having a power source is provided. The power source uses reverse electrowetting technology to generate a charge to power the implantable device. The power source includes a flexible, non-conductive substrate having a first side and a second side opposite the first side with a channel between the first and second sides. Electrodes are arranged about the channel in a predefined pattern. A liquid is contained in the channel. The liquid includes a dielectric liquid and a conductive liquid that do not mix. The electric change is generated by moving the liquid back and forth across the electrodes. The force to pump or move the liquid is provided by organic means, such as, for example, the change in blood pressure between systolic and diastolic, the expansion and contraction of an organ, or the movement of a muscle.

Devices and methods for implantation at a native mitral valve. One embodiment of the device includes a valve support having a first region and a second region, and anchoring member having a longitudinal dimension with a first portion configured to contact tissue at the non-circular annulus, a second portion configured to be attached to the valve support, and a lateral portion transverse to the longitudinal dimension between the first portion and the second portion. The anchoring member and the valve support are configured to move from a low-profile configuration to an expanded configuration in which the first portion of the anchoring member at least partially adapts to the non-circular annulus of the native mitral valve and a shape of the first region of the valve support is at least partially independent of a shape of the first portion of the anchoring member.