Tax-credit scholarship programs in 17 states collected $1.1 billion in contributions in 2017, a new analysis from the GAO finds.

Source: El Periódico - Las políticas climáticas que se centran en la agricultura y los bosques podrían llevar al aumento de los precios de los alimentos, pero reducir la deforestación e incrementar la captura de carbono en la agricultura podría reducir significativamente las emisiones de gases de efecto invernadero, evitando riesgos para la seguridad alimentaria, según un nuevo estudio publicado en 'Environmental Research Letters'.

Extreme preterm birth is associated with developmental shortcomings that may reduce exercise capacity and participation in physical activities in later life. The number of studies addressing these issues in adolescent populations is limited, test methods differ, and results are diverging.

Exercise capacity after preterm birth was in the same range as in term-born control subjects. Participation in physical activity was lower in preterm subjects compared with control subjects; however, the response to exercise in terms of increased aerobic capacity was similar. (Read the full article)

Preterm infants from 33 gestational weeks can detect specific shape features (prism and cylinder) by touch (without visual control), and remember them; however, nothing is known about such abilities earlier in development.

The preterm infant, even when very immature (from 28 gestational weeks), is endowed with tactile sensory abilities: the exploration and memorization of an object by touch, the discrimination of a novel object, and the recognition of a familiar object after interference. (Read the full article)

Sudden infant death syndrome remains the major cause of postneonatal death in developed countries. Although infant-parent bed-sharing following antenatal smoking or maternal consumption of alcohol on the bed-sharing night increases the risk of death, the mechanism is not known.

Bed-sharing infants experienced more oxygen desaturations and episodes of carbon dioxide rebreathing than cot-sleeping infants but showed appropriate behavioral and physiologic responses. A deficit in these responses in vulnerable infants could link to increased risk of sudden infant death syndrome. (Read the full article)

Few reports have explored the measurement validity of the relative value unit (RVU) system, particularly in pediatrics. The RVU system, although broadly applied in health care settings, was developed for the adult population and thus may possess unique inadequacies in pediatrics.

We found deficiencies in the ability of the RVU system to capture features of case mix complexity and differences related to age. Additional investigation may be warranted to determine the validity of RVU as a measurement tool in pediatrics. (Read the full article)

Resistance exercise is known to have a robust effect on glycemic control and cardiometabolic health among children and adolescents, even in the absence of weight loss.

Normalized strength capacity is associated with lower cardiometabolic risk clustering in boys and girls, even after adjustment for cardiorespiratory fitness, level of physical activity, and BMI. (Read the full article)

The population of youth with chronic medical conditions is growing and many attend college. Yet we know little about US colleges’ capacity to identify and care for these youth, nor how transition guidelines and financing models should incorporate college health.

This is the first study to find that although many colleges can provide some clinical care for youth with chronic conditions, few colleges have systems to identify and track these students, elucidating gaps that pediatricians and institutions need to address. (Read the full article)

Authorities unable or unwilling to face up to a reality that might reveal their own shortcomings and ineptitude, usually resort to pinpointing a scapegoat. This year, Covid-19 fits that bill, says Terry Bell.

Despite the worldwide re-emergence of the chikungunya virus (CHIKV) and the high morbidity associated with CHIKV infections, there is no approved vaccine or antiviral treatment available. We here aim to identify the target of a novel class of CHIKV inhibitors i.e. CHVB series. CHVB compounds inhibit the in vitro replication of CHIKV isolates with 50% effective concentrations in the low micromolar range. A CHVB-resistant variant (CHVB^res) was selected that carried two mutations in the gene encoding nsP1 (responsible for viral RNA capping), one mutation in nsP2 and one mutation in nsP3. Reverse genetics studies demonstrated that both nsP1 mutations were necessary and sufficient to achieve ~18-fold resistance, suggesting that CHVB targets viral mRNA capping. Interestingly, CHVB^res was cross-resistant to the previously described CHIKV capping inhibitors from the MADTP series, suggesting they share a similar mechanism of action. In enzymatic assays, CHVB inhibited the methyltransferase and guanylyltransferase activities of alphavirus nsP1 proteins. To conclude, we identified a class of CHIKV inhibitors that targets the viral capping machinery. The potent anti-CHIKV activity makes this chemical scaffold a potential candidate for CHIKV drug development.

Two non-amidated host defence peptides named Pin2[G] and FA1 were evaluated against three types of pathogenic bacteria; two isolated from diabetic foot ulcer patients, Staphylococcus aureus UPD13 and Pseudomonas aeruginosa UPD3, and another from a commercial collection, Salmonella enterica serovar Typhimurium (ATCC 14028). In vitro experiments showed that the antimicrobial performance of the synthetic peptides, Pin2[G] and FA1, was modest, although FA1 was more effective than Pin2[G]. In contrast Pin2[G] had superior in vivo anti-infective activity to FA1 in rabbit wound infections by the diabetic foot ulcer pathogens S. aureus UPD13 and P. aeruginosa UPD3. Indeed, Pin2[G] reduced bacterial colony counts of both S. aureus UPD13 and P. aeruginosa UPD3 by >100,000-fold after 48-72 h on skin wounds of infected rabbits, while in similar infected wounds, FA1 had no major effects at 72-96 h of treatment. Ceftriaxone was equally effective vs. Pseudomonas but less effective vs. S. aureus infections. Additionally, the two peptides were evaluated in mice against intragastrically inoculated S. enterica ser. Typhimurium (ATCC 14028). Only Pin2[G], at 0.56 mg/kg, was effective in reducing systemic (liver) infection by >67-fold, equivalent to the effect of treatment with levofloxacin. Pin2[G] showed superior immunomodulatory activity in increasing chemokine production by a human bronchial cell line and suppressing poly(IC)-induced pro-inflammatory IL6 production. These data showed that the in vitro antimicrobial activity of these peptides was not correlated with their in vivo anti-infective activity, and suggest that other factors such as immunomodulatory activity were more important.

The UEFA Champions League is back and UEFA.com are here to guide #UCLfantasy managers through the first legs of the round of 16.

Gauteng, the Western Cape and KwaZulu-Natal are the hot spots for card fraud in South Africa, according to a report on global fraud activity.

Extremely low or negative yields in global markets make it challenging for investors to generate meaningful returns, says Brian McMillan of Investec Structured Products.

With the best scanning and OCR apps, you can save whiteboard text, business cards, and important documents so that you can not only read them, but also edit them.

The Herald is bringing you the latest coronavirus news and updates from Scotland, the UK and the world.

Reliable tipster Evan Blass shares details of HMD Global's next budget Android 10 smartphone, which is expected to be called the Nokia 5.2.

UEFA EURO 2016 dominated the UEFA.com landscape for much of the year, but how much do you remember? Allow us to recap the headline news from a memorable summer in France.

As the round of 16 comes to a conclusion, UEFA.com presents a captaincy option for each of the four gamedays.

A new supercapacitor based on manganese oxide could combine the storage capacity of batteries with the high power and fast charging of other supercapacitors, according to researchers at Penn State and two universities in China.

After months of hard work and preparation, nearly a dozen Penn State Hazleton seniors are now one step closer to graduating after presenting their Capstone Research and Design Thesis projects.

To view more press releases, please visit http://ir.wintrust.com/news.aspx?iid=1024452.

Somerset West stands out as one of the fastest growing property areas – commercial, residential and industrial - in the Western Cape, according to a new report on the state of the property sector in the Western Cape.

All three property sectors – residential, commercial and industrial – are currently experiencing a so-called buyers’ market in the Western Cape, says David Maynier, Western Cape Minister of Finance and Economic Opportunities.

The Cape Town metro scooped the highest prices paid for residential property in South Africa this year, says the MD of Seeff Atlantic Seaboard and City Bowl.

Super-rich visitors to Cape Town over the holiday season have once again been willing to dig deep into their pockets for luxury rental accommodation.

Cape Town's East City Precinct - between the CBD and District Six - are undergoing a revival and the new The Harri residential development is an example of this trend.

Construction work on FWJK's R800 million residential development known as 16 on Bree has topped out with the 36th floor having been cast.

Gianluigi Buffon won his 175th and final Italy cap on Monday, a record for a European. Could that soon be under threat, though? We check out the top ten.

The Nebula Capsule II by Anker is an unusual entertainment projector: It runs the Android TV operating system, and can double as a Bluetooth speaker.

The 63-year-old was found living in a remote cave on the side of a steep cliff.

The DJI Mavic Mini weighs just 249 grams, so you can fly it in the US—and many other regions—without having to register it with the government. It has very capable specifications, but also some artificial limitations we're not happy to see.

Although cash should still be seen as a "trashy" asset class, investors do not have many other places to park their money, says an analyst.

The City of Cape Town has partnered with Barcelona to set up an "entrepreneurship ecosystem".

How to overcome enhanced index ETF data.

Lebanese banks are working on a national financial rescue plan that would preserve some of their capital rather than writing it all off as outlined in a government program, the banking association head said.

  September 3, 2019 Delaware is a finalist for non-Asian domicile of the year.  Captive Review magazine released the shortlists for the 2019 Asia Captive Awards for both captive insurance domiciles in Asia and non-Asian domiciles having a significant presence on the continent. “The Delaware Insurance Department has one of the highest international profiles of […]

Captives reduce taxpayer burden Insurance Commissioner Trinidad Navarro announced data showing a strong year of captive insurance formations in Delaware, with 56 licenses provided in 2019, outpacing previous years. “The success of Delaware’s captive insurance program is reflective of the hard work of Delaware’s captive staff in applying firm but fair regulations and finding innovative […]

In India, however, this is not likely to be a separate offering — Disney titles are being made available on the homegrown Hotstar, with no change in subscription plans, as of now.

Billionaire Mukesh Ambani just sealed three deals in as many weeks to raise a combined $8 billion, including from Facebook Inc.

The Delaware Forest Service funded a streetscape project in Georgetown, highlighted by the planting of 18 new cherry and lilac trees along East Market Street near the Sussex County Courthouse. Total cost was estimated at $37,000.

Agency: CSD Closing Date: 5/13/2020

NEW CASTLE (Sept. 26, 2019) – The Centers for Medicare and Medicaid Services (CMS) recently awarded the Delaware Department of Health and Social Services a $3.58 million planning grant to increase the treatment capacity of Medicaid providers to deliver substance use disorder treatment and recovery services to Delawareans in need. Delaware was one of 15 […]

Start meditation and yoga for physical gain especially mental toughness. Today, you are likely to attain economic benefits due to your children. This will make you very happy. Good advice from family members will decrease your mental pressure. Today, you will not be able to fulfill any of your promises, which can make your lover grumpy. You can waste your free time today on surfing on mobile or watching TV. Seeing this can annoy your spouse, as you will not show any interest in talking to them. You might fight today on an old issue with your spouse like he/she forgot your birthday, or something like that. But, everything will be alright at the end of the day. Avoid stepping out of your boundaries while joking with friends, as it can ruin your friendship.

LEWES – The Point at Cape Henlopen State Park, including a stretch of ocean beach and dunes, and a half-mile along the bay shoreline, will close Sunday, March 1, for the benefit of threatened and endangered beachnesters and migratory shorebirds, including red knot, piping plovers, oystercatchers, least terns, and other species. The Point’s nesting habitat […]