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Usage of supercritical fluid techniques to obtain bioactive alkaloid-rich extracts from cherimoya peel and leaves: extract profiles and their correlation with antioxidant properties and acetylcholinesterase and α-glucosidase inhibitory activities

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00342E, Paper
Oscar Galarce-Bustos, Mª Teresa Fernández-Ponce, Antonio Montes, Clara Pereyra, Lourdes Casas, Casimiro Mantell, Mario Aranda
The wastes generated by cherimoya cultivation and processing industries should be contemplated as a valuable source of bioactive alkaloids, with potential in pharmaceutical applications for the treatment or prevention of chronic diseases.
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Superior hypoglycemic activity of mulberry lacking monosaccharides is accompanied by better activation of the PI3K/Akt and AMPK signaling pathways

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00427H, Paper
Xiao-Shan Long, Sen-Tai Liao, Peng Wen, Yu-Xiao Zou, Fan Liu, Wei-Zhi Shen, Teng-Gen Hu
Mulberry removed monosaccharides (FM) displayed better hypoglycemic activity than untreated mulberry (MP), which may be attributed the stronger effects of FM on activating PI3K/Akt and AMPK signaling pathways.
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Lactobacillus fermentum CECT5716 prevents renal damage in NZBWF1 mice model of systemic lupus erythematosus

Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/D0FO00578A, Paper
Néstor de la Visitación, Iñaki Robles-Vera, Marta Toral, Francisco O’Valle, Javier Moleon, Manuel Gómez-Guzmán, Miguel Romero, Marcos Duarte, Manuel Sanchez, Rosario Jimenez, Juan Duarte
The aim of this work was to evaluate whether the immune-modulatory bacteria Lactobacillus fermentum CECT5716 (LC40) protects kidneys in a female mouse model of lupus with hypertension. Twenty-week-old NZBWF1 (lupus)...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Kinetic profile and urinary excretion of phenyl-γ-valerolactones upon consumption of cranberry: a dose-response relationship

Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/D0FO00806K, Paper
Claudia Favari, Pedro Mena, Claudio Curti, Geoffrey Istas, Christian Heiss , Daniele Del Rio, Ana Rodriguez-Mateos
Cranberries are a rich source of poly(phenols), mainly monomeric and oligomeric flavan-3-ols. However, information on the appearance of their main circulating microbial metabolites, namely phenyl-γ-valerolactones and phenylvaleric acid, is lacking...
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Pedro Ximenez sun-dried grape must: a dietary supplement for a healthy longevity

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00204F, Paper
Noelia Morales-Prieto, Paula V. Huertas-Abril, Nieves López de Lerma, Isabel. L. Pacheco, José Pérez, Rafael Peinado, Nieves Abril
Sun-dried Pedro Ximénez white grapes must (PXM) is a potent antioxidant that regularizes apoptosis, proliferation, and regeneration of the structure and the function of aged mice liver. PXM consumption contributes to a healthy aging process.
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Dietary supplementation of L-arginine and N-carbamylglutamate enhances duodenal barrier and mitochondrial functions and suppresses duodenal inflammation and mitophagy in suckling lambs suffering from intrauterine-growth-restriction

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00019A, Paper
Hao Zhang, Yi Ma, Mengzhi Wang, Mabrouk Elsabagh, Juan J. Loor, Hongrong Wang
The work aimed at investigating the effects of N-carbamylglutamate (NCG) or L-arginine (Arg) supplementation on the duodenal mitophagy, inflammation, and barrier function in suckling lambs suffering from intrauterine-growth-retardation (IUGR).
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Supplementation of Bacillus amyloliquefaciens AS385 culture broth powder containing 1-deoxynojirimycin in a high-fat diet altered the gene expressions related to lipid metabolism and insulin signaling in mice epididymal white adipose tissue

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00271B, Paper
Isabella Supardi Parida, Soo Takasu, Junya Ito, Ryoichi Ikeda, Kenji Yamagishi, Toshiyuki Kimura, Takahiro Eitsuka, Kiyotaka Nakagawa
Supplementation of Bacillus amyloliquefaciens AS385 culture broth powder in high-fat diet restored adiposity, glucose tolerance and insulin sensitivity in mice.
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Pterostilbene prevents LPS-induced early pulmonary fibrosis by suppressing oxidative stress, inflammation and apoptosis in vivo

Food Funct., 2020, Advance Article
DOI: 10.1039/C9FO02521A, Paper
Huahong Yang, Cong Hua, Xiaolin Yang, Xiaoye Fan, Hongyu Song, Liping Peng, Xinxin Ci
Schematic model of the protective effects by Pts on LPS-induced lung fibrosis.
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Polysaccharides from Enteromorpha prolifera protect against carbon tetrachloride-induced acute liver injury in mice via activation of Nrf2/HO-1 signaling, and suppression of oxidative stress, inflammation and apoptosis

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00575D, Paper
Fuchuan Guo, Xinyun Zhuang, Mengyuan Han, Wenting Lin
EPP protected against hepatic injury induced by CCl4-derived reactive intermediates through the suppression of hepatic oxidative stress, inflammation, and apoptosis.
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PhonePe launches Super Funds to help users in long-term wealth creation

The Super Fund identifies and invests in top funds across various categories and asset management companies




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iOS 9 Available as a Free Update for iPhone, iPad, and iPod touch Users September 16

Apple announced that iOS 9 will be available on September 16 as a free update for iPhone, iPad, and iPod touch users. iOS 9 makes iOS devices more intelligent and proactive with powerful search and improved Siri features, all while protecting users’ privacy. The way you interact with iPad gets even better with iOS 9, thanks to new multitasking features that let users view and interact with two apps at once, side by side. “iOS 9 is packed with intelligence that makes every experience with iPhone and iPad even more powerful — Siri can do more than ever and new proactive assistance helps you get more done before you ask, all while protecting users’ privacy,” said Craig Federighi, Apple’s senior vice president of Software Engineering.




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OS X El Capitan Available as Free Update Tomorrow

OS X El Capitan, the latest major release of the world’s most advanced desktop operating system, will be available Wednesday, September 30, as a free update for Mac users. El Capitan builds on the groundbreaking features and beautiful design of OS X Yosemite. “People love using their Macs, and one of the biggest reasons is the power and ease of use of OS X,” said Craig Federighi, Apple’s senior vice president of Software Engineering. “El Capitan refines the Mac experience and improves performance in a lot of little ways that make a very big difference. Feedback from our OS X beta program has been incredibly positive and we think customers are going to love their Macs even more with El Capitan.”




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Apple Updates iMac Family with Stunning New Retina Displays

Apple has updated the entire iMac family, bringing a new Retina 4K display to the 21.5-inch iMac for the first time and the Retina 5K display to every 27-inch iMac. The updated iMacs also feature more powerful processors and graphics, two Thunderbolt 2 ports, and new storage options that make the high-performance Fusion Drive even more affordable. Apple also introduced a new lineup of wireless accessories including the all-new Magic Keyboard, Magic Mouse 2, and Magic Trackpad 2. “From the first iMac to today, the spirit of iMac has never wavered — deliver the ultimate desktop experience with the latest technologies, gorgeous displays, and cutting-edge designs,” said Philip Schiller, Apple’s senior vice president of Worldwide Marketing. “These are the most stunning iMacs we’ve ever made. With our gorgeous new Retina displays, more powerful processors and graphics, and all-new Magic accessories, the new iMac continues to redefine the ultimate desktop experience.”




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Booo Sabki Phategi Review: Sex, slapstick, stupidity

If there's even the slightest chance of a laugh, its dummy cast ensures the joke doesn't land, feels Sukanya Verma.




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Send us your Super 30 review!

We give you *your* space to tell us just what you felt about Super 30.







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I take responsibility for the rebellion by MLAs: Kishore Upadhyay

Interview with Uttarakhand Pradesh Congress Committee President




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China SUV maker begins upscale climb with luxury brand

Wei Jianjun's Great Wall Motor Co will unveil its WEY brand on November 16





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Easy DIY projects to take up at home during the coronavirus lockdown

Easy DIY projects to take up at home during the coronavirus lockdown




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Anu Emmanuel to pair up with Udhayanidhi in Magizh Thirumeni's film?

Anu Emmanuel to pair up with Udhayanidhi in Magizh Thirumeni's film?




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Salman Khan and Jacqueline Fernandez share the inspiration behind their upcoming track 'Tere Bina' in the second lockdown interview

Salman Khan and Jacqueline Fernandez share the inspiration behind their upcoming track 'Tere Bina' in the second lockdown interview




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Lufthansa Group airlines to take off again in June with 160 aircraft, 106 destinations

Lufthansa Group airlines to take off again in June with 160 aircraft, 106 destinations




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Gujarat: These super-specialists joined forces to save Covid-19 patients

Gujarat: These super-specialists joined forces to save Covid-19 patients




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Ahmedabad lockdown: Today's updates

Ahmedabad lockdown: Today's updates




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Tirupur sees chance as global brands come calling for masks

Tirupur sees chance as global brands come calling for masks




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Newlywed couple drowns while clicking selfie

Newlywed couple drowns while clicking selfie




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Three at Delhi's IGI Airport test positive, CISF’s total number goes up to 14

Three at Delhi's IGI Airport test positive, CISF’s total number goes up to 14




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Delhi lockdown: Today's updates from your city

Delhi lockdown: Today's updates from your city




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Mumbai’s first migrants’ train rolls out from LTT for Basti, UP

Mumbai’s first migrants’ train rolls out from LTT for Basti, UP




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Mumbai lockdown: Today's updates from your city

Mumbai lockdown: Today's updates from your city




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‘Shouted at them to wake up, train was louder’

‘Shouted at them to wake up, train was louder’




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‘COVID-19 death is a wake-up call to improve surveillance in the area’

Even after more than six weeks of national lockdown, there is no sign of any flattening of the curve but instead the number of new novel coronavirus c




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PE/VC deals up by 34% to $2.5 bn in Jan on increased credit investments

After a record-setting 2019, PE/VC investments in 2020 are off to a good start, said Vivek Soni




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Coronavirus impact: Early funding of start-ups may hit a stumbling block

This comes as seed investments in India during the January-March quarter, which was hit by the lowest level in five quarters




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[ASAP] Update to Our Reader, Reviewer, and Author Communities—April 2020

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.0c00431




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[ASAP] Total Synthesis of Isohericenone J via a Stille Coupling Reaction

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b01251




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[ASAP] Effect of Temperature on <sup>1</sup>H NMR Spectra, Antitrypanosomal Activity, Conformational Analysis, and Molecular Docking of Curine Derivatives from <italic toggle="yes">Berberis brevissima</italic>

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b00397




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[ASAP] A Grand Challenge. 3. Unbiased Phenotypic Function of Metabolites from Australia Plants <italic toggle="yes">Gloriosa superba</italic> and <italic toggle="yes">Alangium villosum</italic> against Parkinson

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b00880




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[ASAP] Advances in the Biosynthesis of Pyranocoumarins: Isolation and <sup>13</sup>C-Incorporation Analysis by High-Performance Liquid Chromatography–Ultraviolet–Solid-Phase Extraction–Nuclear Magnetic Resonance Data

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b00607




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Budget's much-needed leg-up for small units: CRISIL SME Tracker

An evaluation of 13,000 MSMEs using the CRISIL Quantix database shows that working capital comprises over half of their need for debt




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Wanted to keep Budget Speech shorter but ended up breaking own record: FM

In July presenting her maiden Budget, Sitharaman had spoken for 2 hours 17 minutes




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Budget proposes to shut thermal power plants of 166,000 mw, says group

National powermen body to stage protests against 'anti-people' proposals




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Effect of Vitamin D3 Supplementation on Upper Respiratory Tract Infections in Healthy Adults: The VIDARIS Randomized Controlled Trial

Interview with Carlos A. Camargo, MD, author of Effect of Vitamin D3 Supplementation on Upper Respiratory Tract Infections in Healthy Adults: The VIDARIS Randomized Controlled Trial




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Challenges at the Intersection of Team-Based and Patient-Centered Health Care: Insights From an IOM Working Group

Interview with Matthew K. Wynia, MD, MPH, author of Challenges at the Intersection of Team-Based and Patient-Centered Health Care: Insights From an IOM Working Group




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Daily Sedation Interruption in Mechanically Ventilated Critically Ill Patients Cared for With a Sedation Protocol

Interview with Sangeeta Mehta, MD, author of Daily Sedation Interruption in Mechanically Ventilated Critically Ill Patients Cared for With a Sedation Protocol




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Effect of Vitamin D Supplementation on Progression of Knee Pain and Cartilage Volume Loss in Patients With Symptomatic Osteoarthritis: A Randomized Controlled Trial

Interview with Timothy McAlindon, DM, MPH, author of Effect of Vitamin D Supplementation on Progression of Knee Pain and Cartilage Volume Loss in Patients With Symptomatic Osteoarthritis: A Randomized Controlled Trial




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Association Between Maternal Use of Folic Acid Supplements and Risk of Autism Spectrum Disorders in Children

Interview with Pål Surén, author of Association Between Maternal Use of Folic Acid Supplements and Risk of Autism Spectrum Disorders in Children