Rayner, N M. Geological Survey of Canada, Open File 8868, 2022, 7 pages, https://doi.org/10.4095/329641
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/gid_329641.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/gid_329641.jpg" title="Geological Survey of Canada, Open File 8868, 2022, 7 pages, https://doi.org/10.4095/329641" height="150" border="1" /></a>

Galloway, J M; Bringué, M; Buryak, S D; Reyes, A V; West, C K; Siver, P A. Geological Survey of Canada, Open File 8864, 2022, 29 pages, https://doi.org/10.4095/329615
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/gid_329615.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/gid_329615.jpg" title="Geological Survey of Canada, Open File 8864, 2022, 29 pages, https://doi.org/10.4095/329615" height="150" border="1" /></a>

Midwinter, D; Hadlari, T; Dewing, K. Geological Survey of Canada, Open File 8855, 2022, 17 pages, https://doi.org/10.4095/329398
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/gid_329398.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/gid_329398.jpg" title="Geological Survey of Canada, Open File 8855, 2022, 17 pages, https://doi.org/10.4095/329398" height="150" border="1" /></a>

Issler, D R; McDannell, K T; O'Sullivan, P B; Lane, L S. Geochronology vol. 4, 2022 p. 373-397, https://doi.org/10.5194/gchron-4-373-2022
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/20210455.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/20210455.jpg" title="Geochronology vol. 4, 2022 p. 373-397, https://doi.org/10.5194/gchron-4-373-2022" height="150" border="1" /></a>

Soucy La Roche, R; Dyer, S C; Zagorevski, A; Cottle, J M; Gaidies, F. Lithos 7708357, 2022, 1-29 pages, https://doi.org/10.2113/2022/7708357
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/20210423.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/20210423.jpg" title="Lithos 7708357, 2022, 1-29 pages, https://doi.org/10.2113/2022/7708357" height="150" border="1" /></a>

McClenaghan, M B; Spirito, W A; Day, S J A; McCurdy, M W; McNeil, R J; Adcock, S W. Geochemistry: Exploration, Environment, Analysis vol. 22, no. 1, geochem2021-070, 2022 p. 1-21, https://doi.org/10.1144/geochem2021-070
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/20210301.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/20210301.jpg" title="Geochemistry: Exploration, Environment, Analysis vol. 22, no. 1, geochem2021-070, 2022 p. 1-21, https://doi.org/10.1144/geochem2021-070" height="150" border="1" /></a>

Handkamer, N M; Pratt, B R; MacNaughton, R B. Journal of Paleontology vol. 96, S89, 2022, 47 pages, https://doi.org/10.1017/jpa.2022.13
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/20210288.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/20210288.jpg" title="Journal of Paleontology vol. 96, S89, 2022, 47 pages, https://doi.org/10.1017/jpa.2022.13" height="150" border="1" /></a>

Re-release; McDannell, K T; Pinet, N; Issler, D R. Sedimentary basins of northern Canada: contributions to a 1000 Ma geological journey and insight on resource potential; by Lavoie, D (ed.); Dewing, K (ed.); Geological Survey of Canada, Bulletin 609, 2022 p. 287-322, https://doi.org/10.4095/326100
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/gid_326100.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/gid_326100.jpg" title="Sedimentary basins of northern Canada: contributions to a 1000 Ma geological journey and insight on resource potential; by Lavoie, D (ed.); Dewing, K (ed.); Geological Survey of Canada, Bulletin 609, 2022 p. 287-322, https://doi.org/10.4095/326100" height="150" border="1" /></a>

Re-release; Larmagnat, S; Lavoie, D. Sedimentary basins of northern Canada: contributions to a 1000 Ma geological journey and insight on resource potential; by Lavoie, D (ed.); Dewing, K (ed.); Geological Survey of Canada, Bulletin 609, 2022 p. 185-213, https://doi.org/10.4095/326091
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/gid_326091.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/gid_326091.jpg" title="Sedimentary basins of northern Canada: contributions to a 1000 Ma geological journey and insight on resource potential; by Lavoie, D (ed.); Dewing, K (ed.); Geological Survey of Canada, Bulletin 609, 2022 p. 185-213, https://doi.org/10.4095/326091" height="150" border="1" /></a>

Re-release; Lavoie, D; Pinet, N; Zhang, S; Reyes, J; Jiang, C; Ardakani, O H; Savard, M M; Dhillon, R S; Chen, Z; Dietrich, J R; Hu, K; Craven, J A; Roberts, B; Duchesne, M J; Brake, V I; Huot-Vézina, G; Galloway, J M; McCracken, A D; Asselin, E; Decker, V; Beauchemin, M; Nicolas, M P B; Armstrong, D K; Hahn, K E. Sedimentary basins of northern Canada: contributions to a 1000 Ma geological journey and insight on resource potential; by Lavoie, D (ed.); Dewing, K (ed.); Geological Survey of Canada, Bulletin 609, 2022 p. 37-76, https://doi.org/10.4095/326090
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/gid_326090.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/gid_326090.jpg" title="Sedimentary basins of northern Canada: contributions to a 1000 Ma geological journey and insight on resource potential; by Lavoie, D (ed.); Dewing, K (ed.); Geological Survey of Canada, Bulletin 609, 2022 p. 37-76, https://doi.org/10.4095/326090" height="150" border="1" /></a>

McNeil, D H; Dixon, J; Xiu, Z; Fowler, S P. Bulletin of Canadian Petroleum Geology vol. 68, no. 4, 2022 p. 141-157, https://doi.org/10.35767/gscpgbull.68.4.141
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/20190288.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/20190288.jpg" title="Bulletin of Canadian Petroleum Geology vol. 68, no. 4, 2022 p. 141-157, https://doi.org/10.35767/gscpgbull.68.4.141" height="150" border="1" /></a>

Pehrsson, S J (ed.); Wodicka, N (ed.); Rogers, N (ed.); Percival, J A (ed.). Geological Survey of Canada, Bulletin 612, 2023, 419 pages, https://doi.org/10.4095/332492
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/gid_331492.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/gid_331492.jpg" title="Geological Survey of Canada, Bulletin 612, 2023, 419 pages, https://doi.org/10.4095/332492" height="150" border="1" /></a>

Amini, A; Benoit, N; Russell, H A J. Geological Survey of Canada, Open File 9065, 2023, 17 pages, https://doi.org/10.4095/332258
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/gid_332258.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/gid_332258.jpg" title="Geological Survey of Canada, Open File 9065, 2023, 17 pages, https://doi.org/10.4095/332258" height="150" border="1" /></a>

Bingham-Koslowski, N; Grey, M; Pufahl, P; Ehrman, J; Strauss, A. Geoscience Canada vol. 50, 2023 p. 118, https://doi.org/10.12789/geocanj.2023.50.20
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/20220635.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/20220635.jpg" title="Geoscience Canada vol. 50, 2023 p. 118, https://doi.org/10.12789/geocanj.2023.50.20" height="150" border="1" /></a>

Jin, X; Tomimatsu, Y; Yin, R; Onoue, T; Franceschi, M; Grasby, S E; Du, Y; Rigo, M. Earth and Planetary Science Letters vol. 607, 118075, 2023 p. 1-10, https://doi.org/10.1016/j.epsl.2023.118075
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/20220607.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/20220607.jpg" title="Earth and Planetary Science Letters vol. 607, 118075, 2023 p. 1-10, https://doi.org/10.1016/j.epsl.2023.118075" height="150" border="1" /></a>

Kabanov, P B; Abdi, W; Biggin, A J; Bilot, I; van der Boon, A; Gouwy, S; Grasby, S; Minions, N; Percival, J; Thallner, D; Twemlow, C; VandenBerg, R. Geological Survey of Canada, Open File 8940, 2023, 13 pages, https://doi.org/10.4095/331201
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/gid_331201.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/gid_331201.jpg" title="Geological Survey of Canada, Open File 8940, 2023, 13 pages, https://doi.org/10.4095/331201" height="150" border="1" /></a>

Du, Y; Grasby, S E; Xing, T; Song, H; Tien, L; Chu, D; Wu, Y; Dal Corso, J; Algeo, T; Tong, J. Earth and Planetary Science Letters vol. 602, 117944, 2023 p. 1-12, https://doi.org/10.1016/j.epsl.2022.117944
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/20220395.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/20220395.jpg" title="Earth and Planetary Science Letters vol. 602, 117944, 2023 p. 1-12, https://doi.org/10.1016/j.epsl.2022.117944" height="150" border="1" /></a>

Berman, R G; Taylor, B E; Davis, W J; Sanborn-Barrie, M; Whalen, J B. Canada's northern Shield: new perspectives from the Geoscience for Energy and Minerals Program; Geological Survey of Canada, Bulletin 612, 2024 p. 115-158, https://doi.org/10.4095/332497
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/gid_332497.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/gid_332497.jpg" title="Canada's northern Shield: new perspectives from the Geoscience for Energy and Minerals Program; Geological Survey of Canada, Bulletin 612, 2024 p. 115-158, https://doi.org/10.4095/332497" height="150" border="1" /></a>

Posten Bring has rapidly rolled out Europe's longest network of parcel lockers, with 6,000 self-service parcel lockers at 2,000 locations across Norway.

Together with technology partner Nuki, Austrian Post is launching in-house delivery as a regular service.

1. State’s $16m to protect babies from virus  MSN
2. World-leading approach to protect babies from RSV  Department of Health
3. New program will see pregnant mothers and babies protected from life-threatening virus  SBS
4. Government-funded RSV vaccines to protect infants from severe disease  Australian Pharmacist
5. Free RSV vaccines for mothers and babies as cases spike by 37,000  Sydney Morning Herald

Ramandeep Singh makes his India debut, gets cap and speech from Hardik Pandya: Here's his story  Hindustan TimesView Full coverage on Google News

1. Even if Indira Gandhi returns from heaven, Article 370 will not be restored: Amit Shah  Greater Kashmir
2. 'Even if Indira Gandhi returns from heaven ... ': What Amit Shah said on Article 370 and Muslim reservati  The Times of India
3. Article 370 won’t be restored even if Indira Gandhi returns from heaven: Amit Shah  India Today
4. Maharashtra Assembly elections 2024: ‘Language of Pakistan’: Modi, Shah criticise Congress push to reinstate Article 370  The Hindu
5. UP CM Yogi Adityanath: 'Even 4th generation of Congress will not be able to restore Article 370 in Kashmir'  India.com

It is adorable, practical, and so green. READ MORE...

The airline reported a revenue decrease of $61m compared to the same time last year

For many Welsh speakers, Eryri and Yr Wyddfa are the names they have used all along.

Filed under: Business, Talking Travel

Skift Acquires Gadling Travel From AOL originally appeared on Gadling on Thu, 12 Jun 2014 09:04:00 EST. Please see our terms for use of feeds.

Endogenous reprogramming of glia into neurogenic progenitors holds great promise for neuron restoration therapies. Using lessons from regenerative species, we have developed strategies to stimulate mammalian Müller glia to regenerate neurons in vivo in the adult retina. We have demonstrated that the transcription factor Ascl1 can stimulate Müller glia neurogenesis. However, Ascl1 is only able to reprogram a subset of Müller glia into neurons. We have reported that neuroinflammation from microglia inhibits neurogenesis from Müller glia. Here we found that the peripheral immune response is a barrier to CNS regeneration. We show that monocytes from the peripheral immune system infiltrate the injured retina and negatively influence neurogenesis from Müller glia. Using CCR2 knock-out mice of both sexes, we found that preventing monocyte infiltration improves the neurogenic and proliferative capacity of Müller glia stimulated by Ascl1. Using scRNA-seq analysis, we identified a signaling axis wherein Osteopontin, a cytokine highly expressed by infiltrating immune cells is sufficient to suppress mammalian neurogenesis. This work implicates the response of the peripheral immune system as a barrier to regenerative strategies of the retina.

The activation of autonomic and hypothalamo-pituitary-adrenal (HPA) systems occurs interdependently with behavioral adjustments under varying environmental demands. Nevertheless, laboratory rodent studies examining the neural bases of stress responses have generally attributed increments in these systems to be monolithic, regardless of whether an active or passive coping strategy is employed. Using the shock probe defensive burying test (SPDB) to measure stress-coping features naturalistically in male and female rats, we identify a neural pathway whereby activity changes may promote distinctive response patterns of hemodynamic and HPA indices typifying active and passive coping phenotypes. Optogenetic excitation of the rostral medial prefrontal cortex (mPFC) input to the ventrolateral periaqueductal gray (vlPAG) decreased passive behavior (immobility), attenuated the glucocorticoid hormone response, but did not prevent arterial pressure and heart rate increases associated with rats’ active behavioral (defensive burying) engagement during the SPDB. In contrast, inhibition of the same pathway increased behavioral immobility and attenuated hemodynamic output but did not affect glucocorticoid increases. Further analyses confirmed that hemodynamic increments occurred preferentially during active behaviors and decrements during immobility epochs, whereas pathway manipulations, regardless of the directionality of effect, weakened these correlational relationships. Finally, neuroanatomical evidence indicated that the influence of the rostral mPFC->vlPAG pathway on coping response patterns is mediated predominantly through GABAergic neurons within vlPAG. These data highlight the importance of this prefrontal->midbrain connection in organizing stress-coping responses and in coordinating bodily systems with behavioral output for adaptation to aversive experiences.

The sudden appearance of a visual distractor shortly before saccade initiation can capture spatial attention and modulate the saccade trajectory in spite of the ongoing execution of the initial plan to shift gaze straight to the saccade target. To elucidate the neural correlates underlying these curved saccades, we recorded from single neurons in the frontal eye field of two male rhesus monkeys shifting gaze to a target while a distractor with the same eccentricity appeared either left or right of the target at various delays after target presentation. We found that the population level of presaccadic activity of neurons representing the distractor location encoded the direction of the saccade trajectory. Stronger activity occurred when saccades curved toward the distractor, and weaker when saccades curved away. This relationship held whether the distractor was ipsilateral or contralateral to the recorded neurons. Meanwhile, visually responsive neurons showed asymmetrical patterns of excitatory responses that varied with the location of the distractor and the duration of distractor processing relating to attentional capture and distractor inhibition. During earlier distractor processing, neurons encoded curvature toward the distractor. During later distractor processing, neurons encoded curvature away from the distractor. This was observed when saccades curved away from distractors contralateral to the recording site and when saccades curved toward distractors ipsilateral to the recording site. These findings indicate that saccadic motor planning involves dynamic push–pull hemispheric interactions producing attraction or repulsion for potential but unselected saccade targets.

The prefrontal cortex is critical for decision-making across species, with its activity linked to choosing between options. Drift diffusion models (DDMs) are commonly employed to understand the neural computations underlying this behavior. Studies exploring the specific roles of regions of the rodent prefrontal cortex in controlling the decision process are limited. This study explored the role of the prelimbic cortex (PLC) in decision-making using a two-alternative forced-choice task. Rats first learned to report the location of a lateralized visual stimulus. The brightness of the stimulus indicated its reward value. Then, the rats learned to make choices between pairs of stimuli. Sex differences in learning were observed, with females responding faster and more selectively to high-value stimuli than males. DDM analysis found that males had decreased decision thresholds during initial learning, whereas females maintained a consistently higher drift rate. Pharmacological manipulations revealed that PLC inactivation reduced the decision threshold for all rats, indicating that less information was needed to make a choice in the absence of normal PLC processing. μ-Opioid receptor stimulation of the PLC had the opposite effect, raising the decision threshold and reducing bias in the decision process toward high-value stimuli. These effects were observed without any impact on the rats’ choice preferences. Our findings suggest that PLC has an inhibitory role in the decision process and regulates the amount of evidence that is required to make a choice. That is, PLC activity controls "when," but not "how," to act.

Basolateral amygdala (BLA) neurons are engaged by emotionally salient stimuli. An area of increasing interest is how BLA dynamics relate to evolving reward-seeking behavior, especially under situations of uncertainty or ambiguity. Here, we recorded the activity of individual BLA neurons in male rats across the acquisition and extinction of conditioned reward seeking. We assessed ongoing neural dynamics in a task where long reward cue presentations preceded an unpredictable, variably time reward delivery. We found that, with training, BLA neurons discriminated the CS+ and CS– cues with sustained cue-evoked activity that correlated with behavior and terminated only after reward receipt. BLA neurons were bidirectionally modulated, with a majority showing prolonged inhibition during cued reward seeking. Strikingly, population-level analyses revealed that neurons showing cue-evoked inhibitions and those showing excitations similarly represented the CS+ and behavioral state. This sustained population code rapidly extinguished in parallel with conditioned behavior. We next assessed the contribution of the orbitofrontal cortex (OFC), a major reciprocal partner to the BLA. Inactivation of the OFC while simultaneously recording in the BLA revealed a blunting of sustained cue-evoked activity in the BLA that accompanied reduced reward seeking. Optogenetic disruption of BLA activity and OFC terminals in the BLA also reduced reward seeking. Our data indicate that the BLA represents reward-seeking states via sustained, bidirectional cue-driven neural encoding. This code is regulated by cortical input and is important for the maintenance of vigilant reward-seeking behavior.

Belen, 20, discovers she doesn't need to wait to serve God in missions when He sends her to Africa for six weeks.

Twenty students graduate OM Russia’s Discipleship programme with a heart for missions.

OM Russia’s Business for Transformation ministry supports eight projects that empower locals through employment, while impacting the kingdom.

Nineteen boys and girls graduated from Fishport Kids Tutorial Club's day care programme in Manila, Philippines, this month.

From 8-26 April, OM Philippines will host their annual short-term missions conference GO EXTRA MILE in Palawan for the first time ever.

God can accomplish much when learning moves outside the classroom and a mission student serves in Namibia.

In 2008, the Greek Evangelical Church in Athens opened a community centre, in a suburb where many Albanians live. OM worker Martha describes how she and other staff are reaching out with God's love to local young people.

OM Greece and partner organisations help Syrians and other refugees as they reach the island of Lesbos from Turkey and disembark from dinghies.

Surprises await Bus4Life coordinator Esko when visiting a Romanian village: Meeting orphaned girls saved on a visit 26 years ago, and the former Chief of Police from the Communist era.

OM workers explain, their home has become a mix of Latin American and Middle Eastern cultures.

OM teams in the Near East Field share ministry updates from Jordan, Lebanon, Syria and Iraq.