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Computer-aided discovery of phenylpyrazole based amides as potent S6K1 inhibitors

RSC Med. Chem., 2020, Advance Article
DOI: 10.1039/C9MD00537D, Research Article
Yan Yin, Yuxing Sun, Lianhua Zhao, Jinpeng Pan, Yangbo Feng
Ribosomal protein S6 kinase beta-1 (S6K1) is an attractive therapeutic target.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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No spectators allowed at Hungarian GP

'We do believe that staging the event behind closed doors, which our fans can still watch on television, is preferable to not having a race at all.'




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After net neutrality: a new deal for the digital age / Victor Pickard and David Elliot Berman

Dewey Library - HE7645.P535 2019




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Performance of longitudinal barriers on curved, superelevated roadway sections / Dhafer Marzougui; Cing-Dao "Steve" Kan; Umashankar Mahadevaiah; Fadi Tahan; Christopher Story; Stefano Dolci; Alberto Moreno; Kenneth S. Opiela; Richard Powers

Barker Library - TE7.N275 no.894




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Nodes in Transport Networks - Research, Data Analysis and Modelling: 16th Scientific and Technical Conference "Transport Systems. Theory and Practice 2019", Selected Papers / Elżbieta Macioszek, Nan Kang, Grzegorz Sierpiński, editors

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Decision-making for sustainable transport and mobility: multi actor multi criteria analysis / edited by Cathy Macharis (Professor, Vrije University Brussel-Research group MOBI (Mobility, Logistics and Automotive Technology), dep. BUTO, Belgium), Gino Baud

Rotch Library - HE305.D36 2018




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The highway capacity manual: a conceptual and research history. / Elena S. Prassas, Roger P. Roess

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Light metals 2020 Alan Tomsett, editor

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European port cities in transition: moving towards more sustainable sea transport hubs / Angela Carpenter, Rodrigo Lozano, editors

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Landscape development and management practices for urban freeway roadsides / Beverly J. Storey, John Habermann

Barker Library - HE336.E94 S76 2019




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Female pelvic surgery Farzeen Firoozi, editor

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18th Conference of Power System Engineering, Thermodynamics and Fluid Mechanics: 11-13 June 2019, Pilsen, Czech Republic / editors, Lukáš Richter, Michal Volf, Michaela Vacková, Petr Pavlíček and Miroslav Krejčí

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ICTE in Transportation and Logistics 2019 Egils Ginters, Mario Arturo Ruiz Estrada, Miquel Angel Piera Eroles, editors

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Knowledge management and engineering with decisional DNA Edward Szczerbicki, Cesar Sanin, editors

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Sustainability management and business strategy in Asia / editors, Katsuhiko Kokubu, Yoshiyuki Nagasaka

Dewey Library - HD30.255.S869 2020




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Underground works under special conditions: proceedings of the Workshop (W1) on Underground Works Under Special Conditions, Madrid, Spain, 6-7 July 2007 / editors, Manuel Romana, Áurea Perucho, Claudio Olalla

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Tubular structures XI: proceedings of the 11th International Symposium and IIW International Conference on Tubular Structures, Québec City, Canada, 31 August-2 September 2006 / editors, J.A. Packer & S. Willibald

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Tunnels and underground cities: engineering and innovation meet archaeology, architecture and art. Proceedings of the WTC 2019 ITA-AITES World Tunnel Congress (WTC 2019), May 3-9, 2019, Naples, Italy / editors, Daniele Peila, Giulia Viggiani, Tarcisio Cel

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Web Information Systems Engineering: WISE 2019 Workshop, Demo, and Tutorial, Hong Kong and Macau, China, January 19-22, 2020, Revised selected papers / Leong Hou U, Jian Yang, Yi Cai, Kamalakar Karlapalem, An Liu, Xin Huang (eds.)

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Unsaturated soils: proceedings of the 4th Asia Pacific Conference on Unsaturated Soils, Newcastle, Australia, 23- 25 November 2009 / editors, O. Buzzi, S. Fityus & D. Sheng

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Transit: a history of mass transit in the Puget Sound Region / by Jim Kershner

Dewey Library - HE4487.P84 K47 2019




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Field verification of proposed changes to the AASHTO R 30 procedures for laboratory conditioning of asphalt mixtures / David Newcomb, Edith Arámbula-Mercado, Amy Epps Martin, Mengge Yuan, Texas A&M Transportation Institute; Nam Tran, Fan Yin, Na

Barker Library - TE7.N25 no.919




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Technology innovation in underground construction / editor, Gernot Beer

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Towards user-centric transport in Europe 2: enablers of inclusive, seamless and sustainable mobility / Beate Müller, Gereon Meyer, editors

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Tunnelling: a decade of progress: GeoDelft 1995-2005 / editors, A. Bezuijen, H. van Lottum

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Diverse applications and transferability of maturity models / Shadrack Katuu [editor]

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Recent trends in environmental hydraulics: 38th International School of Hydraulics / Monika B. Kalinowska, Magdalena M. Mrokowska, Paweł M. Rowiński, editors

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The International Academy of Cytology Yokohama System for Reporting Breast Fine Needle Aspiration Biopsy Cytopathology Andrew S. Field, Wendy A. Raymond, Fernando Schmitt, editors

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Computation and big data for transport: digital innovations in surface and air transport systems / Pedro Diez, Pekka Neittaanmäki, Jacques Periaux, Tero Tuovinen, Jordi Pons-Prats, editors

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Obstetric anesthesia: a case-based and visual approach / Thomas L. Archer, editor

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Industry competitiveness: digitalization, management, and integration. / Aleksei V. Bogoviz, Yulia V. Ragulina, editors

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Responsible research for better business: creating useful and credible knowledge for business and society / László Zsolnai, Mike J. Thompson, editors

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Atlas of hysteroscopy Andrea Tinelli, Luis Alonso Pacheco, Sergio Haimovich, editors

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Research methodology in management and industrial engineering Carolina Machado, J. Paulo Davim, editors

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After coal: stories of survival in Appalachia and Wales / Tom Hansell

Hayden Library - TN805.A5 H36 2018




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Technological and modern irrigation environment in Egypt: best management practices & evaluation / El-Sayed E. Omran, Abdelazim M. Negm, editors

Online Resource




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Toxic shock: a social history / Sharra L. Vostral

Hayden Library - RG220.V67 2018




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Cesarean section: an American history of risk, technology, and consequence / Jacqueline H. Wolf

Hayden Library - RG761.W65 2018




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A telephone for the world: Iridium, Motorola, and the making of a global age / Martin Collins

Dewey Library - HE7797.I75 C65 2018




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Ecology in transport: problems and solutions / Aleksander Sładkowski, editor

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Success factors for future growth of car sharing services Jens Kopp

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Advanced joining processes Lucas F. M. da Silva, Paulo A.F. Martins, Mohamad S. El-Zein, editors

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XIXth Conference of PhD Students and Young Scientists: "Interdisciplinary topics in mining and geology": 29-31 May 2019, Sosnówka near Karpacz, Poland / Editors, Jan Blachowski

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Green, smart and connected transportation systems: proceedings of the 9th International Conference on Green Intelligent Transportation Systems and Safety. / Wuhong Wang, Martin Baumann, Xiaobei Jiang, editors

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Modern Japan [electronic resource] : a social and political history / Elise K. Tipton

London ; New York : Routledge, 2008




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Welcome to the Educator Impact Laboratory

The Educator Impact Laboratory is a center at Mathematica designed to expand our collaborations with state and local education agencies around the challenging task of measuring the impact that teachers and principals have on their students and using this information in creative ways to improve outcomes.




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Déjà vu and the end of history / Paolo Virno ; translated by David Broder

Virno, Paolo, 1952-




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Modern Japan : a history in documents / James L. Huffman

Huffman, James L., 1941-




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A history of the world in 100 objects : from the British Museum / The British Museum, Western Australian Museum, National Museum of Australia




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A sarong for Clio : essays on the intellectual and cultural history of Thailand : inspired by Craig J. Reynolds / Maurizio Peleggi, editor