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Vehicle travel control device

A vehicle travel control device can accurately determine a driver's intention to adjust the vehicle speed. After applying attention attracting reaction force corresponding to outside circumstances and the like to an accelerator pedal through a reaction force application mechanism, a reaction force control unit outputs intention determining reaction force that is used to determine the driver's intention to adjust the vehicle speed and is smaller than the attention attracting reaction force, and determines the intention to adjust the vehicle speed on the basis of the accelerator pedal operation amount of the driver while the intention determining reaction force is being applied to the accelerator pedal through the reaction force application mechanism.




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Power steering device

A power steering device is mounted on a vehicle and includes a variable transmission ratio mechanism, a torque applying unit, and an applied friction torque changing unit. The torque applying unit sets an applied friction torque applied to the steering wheel and performs a control of applying the applied friction torque to the steering wheel. The applied friction torque changing unit changes the applied friction torque based on the transmission ratio of the variable transmission ratio mechanism.




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Map-assisted sensor-based positioning of mobile devices

Various methods, apparatuses and/or articles of manufacture are provided which may be implemented to estimate a trajectory of a mobile device within an indoor environment. In some embodiments, the trajectory may be estimated without the use of any signal-based positioning information. For example, a mobile device may estimate such a trajectory based, at least in part, on one or more sensor measurements obtained at the mobile device, and further affect the estimated trajectory based, at least in part, on one or more objects identified in an electronic map of the indoor environment.




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Control device and control method for electric powered vehicle

In an electric powered vehicle in which vehicle driving force for reverse running is produced by a traction motor, vehicle driving force is set by a product of a base value set at least based on an accelerator opening and an amplification factor. The amplification factor is set at k1=1.0 during reverse running (V1.0 at the start of reverse running (V≧0) depending on the vehicular speed. The vehicle driving force at the start of reverse running can thereby be made larger than the vehicle driving force after the start of reverse running at the same accelerator opening.




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Control device for hybrid vehicle

A control device for a hybrid vehicle includes a portion determining whether an engine torque is necessary, a portion controlling a motor to make a motor torque be a target torque, an engine rotation speed control portion controlling an engine output shaft to rotate at a target engine rotation speed for sudden start/reacceleration while the clutch being disengaged after starting the engine and before an actual rotation speed of the engine output shaft exceeds a reference target engine rotation speed in a case where the engine torque is necessary, a control portion engaging the clutch after the actual rotation speed exceeds the reference target engine rotation speed, and a portion controlling the engine so that the engine torque is assumed to be a target torque by canceling the control by the engine rotation speed control portion after the actual rotation speed exceeds the reference target engine rotation speed.




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Semiconductor device

A method for bypassing a defective through silicon via x in a group of n adjacent through silicon vias, includes receiving a plurality of relief signals to identify the defective through silicon via x, activating x−1 switch circuits to connect x−1 data circuits to through silicon vias 1 to x−1 in the group of n adjacent through silicon vias, activating n-x switch circuits to connect n-x data circuits to through silicon vias x+1 to n in the group of n adjacent through silicon vias, and activating a switch circuit to connect a data circuit to an auxiliary through silicon via which is adjacent through silicon via n in the group of n adjacent through silicon vias.




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Semiconductor device design method and design apparatus

A relationship between distance from a back bias control section which outputs a control signal for controlling a back bias of a transistor and an amount of noise in the control signal outputted from the back bias control section is found. An increase of jitter corresponding to the amount of the noise in a clock transmitted on a clock path connected to a circuit section (IP macro) is found on the basis of the relationship between the distance from the back bias control section and the amount of the noise. The circuit section and the clock path are placed on the basis of the increase of the jitter and an allowable jitter value for the circuit section.




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Interconnection substrate design supporting device, method of designing interconnection substrate, program, and interconnection substrate

A via disposition information acquiring unit acquires via disposition information indicating a disposition of the plurality of first vias (212). A second conductor information acquiring unit acquires second conductor information indicating disposition positions of a plurality of second conductors (232) repeatedly disposed in the second conductor layer (230). A via extracting unit extracts an extraction via with respect to each of the plurality of second conductors (232). The extraction via is each of the first vias (212) overlapping the second conductor (232). A via selecting unit selects a selection via with respect to each of the plurality of second conductors (232). The selection via is each of first vias (212) selected in a predetermined number from the extraction vias. An opening introducing unit introduces a first opening (234) to each of the plurality of second conductors (232). The first opening (234) overlaps the extraction via not selected by the via selecting unit in plan view.




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Prediction of dynamic current waveform and spectrum in a semiconductor device

A method for accurately determining the shape of currents in a current spectrum for a circuit design is provided. The method includes determining timing and power consumption characteristics. In one embodiment, timing characteristics are provided through a electronic design automation tool. The timing characteristics yield a current pulse time width. In another embodiment, power consumption characteristics are provided by an EDA tool. The power consumption characteristics yield a current pulse amplitude. The shape of the current pulse is obtained by incrementally processing a power analyzer tool over relatively small time increments over one or more clock cycles while capturing the switching nodes of a simulation of the circuit design for each time increment. In one embodiment, the time increments are one nanosecond or less.




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Magnetic tunnel junction device and fabrication

A method of forming a magnetic tunnel junction (MTJ) device includes forming a first MTJ cap layer on a MTJ structure. The first MTJ cap layer includes a first non-nitrified metal. The method also includes forming a second MTJ cap layer over the first MTJ cap layer. The second MTJ cap layer includes a second non-nitrified metal. The method further includes forming a top electrode layer over the second MTJ cap layer. The second MTJ cap layer is conductive and configured to reduce or prevent oxidation.




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Fabrication of a magnetic tunnel junction device

A magnetic tunneling junction device and fabrication method is disclosed. In a particular embodiment, a non-transitory computer-readable medium includes processor executable instructions. The instructions, when executed by a processor, cause the processor to initiate deposition of a capping material on a free layer of a magnetic tunneling junction structure to form a capping layer. The instructions, when executed by the processor, cause the processor to initiate oxidization of a first layer of the capping material to form a first oxidized layer of oxidized material.




dev

Low-loss superconducting devices

Low-loss superconducting devices and methods for fabricating low loss superconducting devices. For example, superconducting devices, such as superconducting resonator devices, are formed with a (200)-oriented texture titanium nitride (TiN) layer to provide high Q, low loss resonator structures particularly suitable for application to radio-frequency (RF) and/or microwave superconducting resonators, such as coplanar waveguide superconducting resonators. In one aspect, a method of forming a superconducting device includes forming a silicon nitride (SiN) seed layer on a substrate, and forming a (200)-oriented texture titanium nitride (TiN) layer on the SiN seed layer.




dev

Superconducting devices with ferromagnetic barrier junctions

A superconducting memory cell includes a magnetic Josephson junction (MJJ) with a ferromagnetic material, having at least two switchable states of magnetization. The binary state of the MJJ manifests itself as a pulse appearing, or not appearing, on the output. A superconducting memory includes an array of memory cells. Each memory cell includes a comparator with at least one MJJ. Selected X and Y-directional write lines in their combination are capable of switching the magnetization of the MJJ. A superconducting device includes a first and a second junction in a stacked configuration. The first junction has an insulating layer barrier, and the second junction has an insulating layer sandwiched in-between two ferromagnetic layers as barrier. An electrical signal inputted across the first junction is amplified across the second junction.




dev

Superconducting electromagnet device, cooling method therefor, and magnetic resonance imaging device

A superconducting magnet device is configured to include: a refrigerant circulation flowpath in which a refrigerant (R) circulates; a refrigerator for cooling vapor of the refrigerant (R) in the refrigerant circulation flowpath; a superconducting coil cooled by the circulating refrigerant (R); a protective resistor thermally contacting the superconducting coil and having an internal space (S); a high-boiling-point refrigerant supply section for supplying a high-boiling-point refrigerant having a higher boiling point than the refrigerant (R) and frozen by the refrigerant (R) to the internal space (S) in the protective resistor; and a vacuum insulating container for at least accommodating the refrigerant circulation flowpath, the superconducting coil, and the protective resistor.




dev

Layered superconductor device

A layered superconductor device includes multiple layers of a single crystal superconducting material having intermittent layers of superconducting material dispersed in a pattern with a second material such that each layer of the multiple layers a single crystal superconducting material are interconnected via superconducting material, allowing for a continuous current path, and a thickness of the superconducting material never exceeds a first predetermined thickness.




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Superconducting magnet device and magnetic resonance imaging system

A superconducting magnet device and a magnetic resonance imaging system not only avoid the need for costly aluminum alloy formers but also lower quench pressure effectively, have a baffle covering the former and the coil, with a gap between the baffle and the coil.




dev

Device and method for the densification of filaments in a long superconductive wire

A device for the high pressure densification of superconducting wire from compacted superconductor material or superconductor precursor powder particles, has four hard metal anvils (5, 6, 7, 8) with a total length (L2) parallel to the superconducting wire, the hard metal anvils borne in external independent pressure blocks (9, 10, 11), which are in turn either fixed or connected to high pressure devices, preferably hydraulic presses. At least one of the hard metal anvils is a free moving anvil (6) having clearances of at least 0.01 mm up to 0.2 mm towards the neighboring hard metal anvils (5, 8), so that no wall friction occurs between the free moving anvil and the neighboring anvils. This allows for high critical current densities Jc at reduced pressure applied to the hard metal anvils.




dev

Energy storage device and operating method

In order to store excess kinetic energy, an energy storage device and an operating method are described, in which the kinetic energy can be partially converted into electrical energy by a first electric machine using at least two electric machines arranged on a shaft and can be partially converted into additional kinetic energy, such as rotational energy, by a second electric machine. The method for energy storage of excess kinetic energy provides for converting kinetic energy partially into electric energy and partially into additional kinetic energy, such as rotational energy.




dev

Magnetic field generation device with alternative quench device

A magnetic field generation device for a magnetic resonance tomography apparatus has a vacuum container that encloses a magnetic coil made of superconducting material, and a conduit of a pipe system is connected with the magnetic coil so as to conduct heat. The pipe system and the conduit are filled with a coolant that places the magnetic coil in a superconducting state during normal operation of the tomography system. A valve connects the pipe system to the interior of a capture container. In the event of non-normal operation, such as a quench, evaporated coolant passes through the valve into the capture container.




dev

Layered superconductor device

A layered superconductor device includes multiple layers of a single crystal superconducting material having intermittent layers of superconducting material dispersed in a pattern with a second material such that each layer of the multiple layers a single crystal superconducting material are interconnected via superconducting material, allowing for a continuous current path, and a thickness of the superconducting material never exceeds a first predetermined thickness.




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Thought recollection and speech assistance device

Some embodiments of the inventive subject matter include a method for detecting speech loss and supplying appropriate recollection data to the user. Such embodiments include detecting a speech stream from a user, converting the speech stream to text, storing the text, detecting an interruption to the speech stream, wherein the interruption to the speech stream indicates speech loss by the user, searching a catalog using the text as a search parameter to find relevant catalog data and, presenting the relevant catalog data to remind the user about the speech stream.




dev

Language model creation device

This device 301 stores a first content-specific language model representing a probability that a specific word appears in a word sequence representing a first content, and a second content-specific language model representing a probability that the specific word appears in a word sequence representing a second content. Based on a first probability parameter representing a probability that a content represented by a target word sequence included in a speech recognition hypothesis generated by a speech recognition process of recognizing a word sequence corresponding to a speech, a second probability parameter representing a probability that the content represented by the target word sequence is a second content, the first content-specific language model and the second content-specific language model, the device creates a language model representing a probability that the specific word appears in a word sequence corresponding to a part corresponding to the target word sequence of the speech.




dev

Biometric voice command and control switching device and method of use

A biometric voice command and control switching device has a microphone assembly for receiving a currently spoken challenge utterance and a reference utterance, and a voice processing circuit for creating electronic signals indicative thereof. The device further includes a memory for storing the electronic signals, and a processor for comparing the electronic signals to determine if there is a match. If there is a match, an interface circuit enables the operable control of the controlled device.




dev

Low power activation of a voice activated device

In a mobile device, a bone conduction or vibration sensor is used to detect the user's speech and the resulting output is used as the source for a low power Voice Trigger (VT) circuit that can activate the Automatic Speech Recognition (ASR) of the host device. This invention is applicable to mobile devices such as wearable computers with head mounted displays, mobile phones and wireless headsets and headphones which use speech recognition for the entering of input commands and control. The speech sensor can be a bone conduction microphone used to detect sound vibrations in the skull, or a vibration sensor, used to detect sound pressure vibrations from the user's speech. This VT circuit can be independent of any audio components of the host device and can therefore be designed to consume ultra-low power. Hence, this VT circuit can be active when the host device is in a sleeping state and can be used to wake the host device on detection of speech from the user. This VT circuit will be resistant to outside noise and react solely to the user's voice.




dev

Service distribution device and service display device

A service distribution device is provided that, when acquiring services to be used in an information terminal mounted in a vehicle or used in its passenger compartment, recognizes service availability beforehand, thereby improving usability of the services. A service distribution device includes an information correlation unit for correlating information that denotes service utilization conditions in relation to travel condition of the vehicle with the services. The service distribution device distributes to an information terminal the information that denotes the service utilization conditions correlated by the information correlation unit along with contents of the relevant service so that the information and the contents can be visibly displayed on a display unit in the information terminal.




dev

Electronic device and method for providing menu using the same

An electronic device and a method for providing a menu are disclosed. The electronic device displays a plurality of words on the screen, detects a first action specifying selection of at least one of the displayed words, searches an option item related to the word selected by the first action, generates at least one menu item based on the selected word and the searched option item, and displays the generated menu item in a first area of the screen.




dev

Information processing apparatus for displaying screen information acquired from an outside device in a designated color

An information processing apparatus configured to display a user interface on a display unit according to screen information acquired from an outside device changes the screen information according to a display attribute set by a user, and if setting of a display attribute of an object included in the screen information is unchangeable, color conversion processing of a specified object included in the screen information is performed and the screen information obtained by executing conversion processing according to the display attribute set by the user with respect to the screen information including the object which has undergone the color conversion processing is displayed.




dev

Adaptive user interface for widescreen devices

Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for adapting user interfaces for devices that include widescreen displays. In one aspect, a method includes determining a size characteristic of a display of a mobile device, determining a size characteristic of content that is to be displayed on the display, and comparing the size characteristic of the content to the size characteristic of the display. The method also includes selecting one or more controls to display in a portion of the display that is not to be used to display the content based on comparing the size characteristic of the content to the size characteristic of the display, displaying the content, and displaying the selected controls in a portion of the display that is not used to display the content.




dev

Device, method, and graphical user interface for managing concurrently open software applications

A method includes displaying a first application view. A first input is detected, and an application view selection mode is entered for selecting one of concurrently open applications for display in a corresponding application view. An initial group of open application icons in a first predefined area and at least a portion of the first application view adjacent to the first predefined area are concurrently displayed. The initial group of open application icons corresponds to at least some of the concurrently open applications. A gesture is detected on a respective open application icon in the first predefined area, and a respective application view for a corresponding application is displayed without concurrently displaying an application view for any other application in the concurrently open applications. The open application icons in the first predefined area cease to be displayed, and the application view selection mode is exited.




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Handheld electronic device and method for performing spell checking during text entry and for providing a spell-check learning feature

A handheld electronic device includes a reduced QWERTY keyboard and is enabled with a disambiguation routine that is operable to disambiguate text input. In addition to identifying and outputting representations of language objects that are stored in the memory and that correspond with a text input, the device is able to perform a spell check routine during input of a text entry and to learn and automatically correct mistakes typically made by the particular user.




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Altering a view of a document on a display of a computing device

A document authoring program provides different views of a document opened by a user. In the editing view, the user can view the document contents and edit the contents in using a menu bar. In the semantic zoom view, the user is presented with a heading pane and a thumbnail pane and the menu bar is removed. The user can toggle from the editing view to the semantic zoom view by zooming out past a defined threshold using various user interface controls. Once the threshold is exceeded, the semantic view is presented. The editing view is returned to by selecting a heading or a thumbnail page, which respectively returns the user the page incorporating the selected heading or to the page incorporating the selected heading. This page will be displayed in the editing view at the same zoom level prior to toggling to the semantic zoom view.




dev

Portable communication device for providing phone calling service

A portable communication device for phone calling is herein disclosed and enabled. The portable communication device includes a USB interface for connecting to an external USB port of a computing device for enabling phone calling services using the portable communication device. Upon connecting the portable communication device to the external USB port of the computing device, a phone calling software component or data stored in the portable communication device may execute for enabling phone calling services. The portable communication device may also include one or more ports, and may include an interface for Ethernet connection for connecting to the Internet and for making phone calls without the need for connecting the portable communication device to the external USB port. The portable communication device may further include a Wi-Fi wireless component for local wireless communication, and may be implemented as an adapter-sized dongle for providing phone calling services.




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Systems and methods for dynamic development and deployment of computing applications using blueprints

Systems and methods for dynamic development and deployment of computing applications including a development framework, a visual design subsystem, and a deployment subsystem, where at runtime the deployment subsystem is operable to dynamically deploy a computing application realized by a blueprint by sending a request at runtime for graphs and components instantiated by the blueprint.




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Virtualizing embedded devices

A device virtualization system is described herein that separates common computer processing tasks of an embedded device from the application-specific peripherals of the embedded device to allow at least some functions of the device to be offloaded to servers or other computing devices. The device virtualization system greatly simplifies management, configuration, and control of virtual embedded devices. Because much of the software of the device runs on the virtualization server, information technology (IT) personnel can be assigned to manage the virtualization server and to apply any updates and diagnose any problems that occur. Moreover, a single server or group of servers can be used to provide virtualization services for a wide variety of virtualized embedded devices for a wide variety of users. Thus, the system enhances the usefulness of embedded devices and allows a longer lifetime and wider variety of uses than embedded devices today.




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Printing device, mobile terminal, and computer readable recording medium for the same

A printing device includes a printing device side wireless communication unit configured to execute wireless communication with a mobile terminal, an operation acquisition unit configured to acquire user operation thereof, and a processor. The processor is configured to acquire operation data which is generated as the operation acquisition unit acquires a user operation, acquire establishment data which is generated as the printing device side wireless communication unit establishes a wireless communication with the mobile terminal, and issue a request control to control the printing device side wireless communication unit to transmit request data requesting the mobile terminal to transmit print data necessary for printing, via the wireless communication, when the establishment data is acquired, the request control being issued in accordance with the operation data as acquired.




dev

Metronome device

The invention relates to a programmable electronic metronome, capable of registering all meter and speed characteristics of any musical work and of producing, when the musical work is to be performed, substantially sharp, perceivable, e.g. acoustic, signals representing said characteristics in the appropriate succession. The metronome comprises a keyboard for producing signals associated with at least three variables, which are bar number, speed and meter, and defining digital values for said variables, which values are stored in at least one volatile electronic memory, comprising segments severally correlated to each of said variables, to define digital data sequences. The metronome further comprises a reader for the data sequences, whereby to associate to each bar number digital values of speed and meter, and a transducer for transforming said values into electric impulses, which produce a corresponding succession of perceivable signals. Preferably a further transducer, having an inlet/outlet, is provided for transforming said data sequences into recording signals, which may be recorded onto and retrieved from a hard memory.




dev

Clock security device

A clock security device to be hung on a wall of a facility such as, for example, a store. The clock face has a convex mirrored surface which provides reflected panoramic view of the facility. The clock security device also includes a mounting bracket which provides for the mounting of the clock security device on the wall with the concave mirrored surface at different positions from parallel to the wall to tilted downwardly at different selected angles to the wall.




dev

Device and method for providing accurate time and/or frequency

A device and method provide for an accurate output from a unit, such as an oscillator and/or clock providing an output indicative of frequency and/or time. The device includes a processing section having a microprocessor that develops a model characterizing the performance of the device, including establishing predicted accuracy variations, and the model is then used to correct the unit output. An external reference is used to provide a reference input for updating the model, including updating of predicted variations of the unit, by comparison of the reference input with the unit output. The ability of the model to accurately predict the performance of the unit improves as additional updates are carried out, and this allows the interval between the updates to be lengthened and/or the overall accuracy of the device to be improved. The accuracy of the output is thus adaptively optimized in the presence of systematic and random variations.




dev

Wind direction indicator and time display device for golf courses

A wind direction indicating and time display unit is provided for use at the tee areas of a golf course. The unit wind direction indicating device is mounted on an upper surface of a support structure and extends upwardly therefrom. The wind direction indicating device includes a support pole, a sleeve mounted for rotation on the pole at the top thereof, a wind direction indicating element, such as a flag, secured to the sleeve and movable in response to changes in wind direction, and a pole support fitting. Secured to the upper surface of the support structure. A time display device, such as a clock, is secured in a laterally facing wall surface of the support structure.




dev

Electronic device, control method for electronic device, recharge-rate estimating method for secondary battery, and charging control method for secondary battery

A first circuit having a first coil electrically charges a second circuit having a second coil through electromagnetic coupling of the two coils. When data signals are to be transferred between the first and second circuits, signal transfer is started only after the second circuit has been charged for a predetermined period of time. The position relationship between the coils is also detected, and a charging/transfer selector changes a duty ratio between charge transfer and data transfer in accordance with the detected result. The charge is transferred in an intermittent manner, and the charging rate is adjusted according to the difference between the voltage of a secondary battery observed during a charging phase and the voltage of the secondary battery observed a certain time after interruption of the charging phase, or vice versa.




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Method for producing display device

An object of the present invention is to provide a method for producing a display device by which a substrate is thinned efficiently. Onto one original substrate having an area for a plurality of display devices, the other original substrate is bonded via a sealing resin layer, the pair of bonded original substrates is divided and separated into a plurality of pairs of substrates of a size of each individual display device, and thereafter a substrate thinning process of thinning the substrates is performed in a state where the substrates are held by substrate holding means.




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Method and device for synchronizing integrated circuits

A method and device for synchronizing the time between at least two integrated circuits (201, 202), which receive the same pulse signal. In the integrated circuits (201, 202) a counter (204, 206) is used to count the number of pulses in the received pulse signal to synchronize the common time between said integrated circuits.




dev

Magnification device for timepiece

The device consists in compensating for the distortion of the characters marked on the dial caused by a lens, by writing the characters with a reverse pin cushion or barrel distortion.




dev

Portable self contained light generating device powered by a flow of falling granular material

A portable self contained light generating device which is powered by a flow of granular material falling under the influence of gravity to impinge upon and cause a paddle wheel to rotate thereby turning a small generator producing electricity to power one or more light emitting diodes for illumination. The device equipped with a multi-position power/illumination control switch and in some embodiments also provided with a battery providing supplemental power.




dev

Control device for mobile body

A control device for a mobile body makes it possible to smoothly correct the deviation of an actual posture of a base body of a mobile body, which travels with the base body thereof moving up and down, from a desired posture of the base body while restraining an overshoot or an undershoot from occurring. To determine a required manipulated variable according to a feedback control law in order to converge a state amount deviation related to the posture of the base body of the mobile body to zero, the feedback gain of the feedback control law is determined by using the time series in a period from current time to predetermined time in the future in the time series of a desired inertial force of the mobile body or the base body. The required manipulated variable is determined by the calculation of the feedback control law on the basis of the determined feedback gain and an observed value of the state amount deviation.




dev

Storage device

To provide a storage device with low power consumption. The storage device includes a plurality of cache lines. Each of the cache lines includes a data field which stores cache data; a tag which stores address data corresponding the cache data; and a valid bit which stores valid data indicating whether the cache data stored in the data field is valid or invalid. Whether power is supplied to the tag and the data field in each of the cache lines is determined based on the valid data stored in the valid bit.




dev

Storage device and method for controlling data invalidation

A storage device according to an embodiment includes: a host interface connected to a host; a memory including a first buffer that stores a logical address range designated by an invalidation instruction received from the host via the host interface and a second buffer that stores an internal logical address range which is an area combination with the logical address range; a nonvolatile memory; and a controller. The controller includes: an invalidation instruction processor that stores the logical address range designated by the invalidation instruction in the first buffer; an area combination executor that generates the internal logical address range by the area combination with the logical address range and stores the internal logical address range in the second buffer; and an invalidation executor that executes invalidation processing on the nonvolatile memory based on the internal logical address range.




dev

Automatically preventing large block writes from starving small block writes in a storage device

A mechanism is provided in a storage device for performing a write operation. The mechanism configures a write buffer memory with a plurality of write buffer portions. Each write buffer portion is dedicated to a predetermined block size category within a plurality of block size categories. For each write operation from an initiator, the mechanism determines a block size category of the write operation. The mechanism performs each write operation by writing to a write buffer portion within the plurality of write buffer portions corresponding to the block size category of the write operation.




dev

Medical devices

Medical devices comprising an anti-connexin agent suitable for introduction into a subject.




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Cytosine analogue, a method of preparation of a cytosine analogue, a DNA methyltransferase 1 inhibitor, a method for DNA methylation inhibition, the use of the analogue in the treatment of diseases associated with deviations from normal DNA methylation

A cytosine analog, a method of preparation of a cytosine analog, a DNA methyltransferase 1 inhibitor, and a method for DNA methylation inhibition, is provided for the treatment of diseases associated with deviations from normal DNA methylation. The analog of cytosine may be comprised of 1, N4, 5 and 6-substituted derivatives of cytosine or 5,6-dihydrocytosine, wherein the analog can be described by the chemical formula where R1 is H, R3, R4, 2'-deoxyribosyl, R4 is alkyl or aryl, X is N or C, wherein if X in the analog of formula I is N, then R5 is no substituent and if X in the analog of formula I and/or II is C or if X in the analog of formula II is N, then R5 and R6 are independently alkyl, aryl, hydroxyalkyl, aminoalkyl, hydroxyl, carboxyl, amino group, alkoxyl, aryloxyl, aminoalkyl, aminoaryl, thio group, sulfonyl, sulfinyl or halogen.