SAN JOSE, Calif., Oct. 16, 2024 — Supermicro, Inc. is launching a new optimized storage system for high performance AI training, inference and HPC workloads. This JBOF (Just a Bunch […]

The post Supermicro Introduces JBOF Storage Platform Powered by NVIDIA BlueField-3 for Scalable AI and HPC appeared first on HPCwire.

An American woman who was traveling in Hungary was killed in Budapest last week allegedly by a man she met on vacation.

Haiti's ruling transitional council has fired Prime Minister Garry Conille, six months after the doctor and former UNICEF Latin America head was appointed to lead the troubled nation.

A flight of Florida-based Spirit Airlines was hit by gunfire while attempting to land in Haiti with a crew member that sustained "minor injuries."

Oct. 31, 2024 — Giga Computing, a subsidiary of GIGABYTE and a leader in generative AI servers and advanced cooling technologies, will participate in today’s AI Accelerator Skyscraper Congress, hosted […]

The post GIGABYTE Joins AI Accelerator Skyscraper Congress to Highlight Sustainable Supercomputing Advances appeared first on HPCwire.

A baby goat stranded on a Hawaii cliff was rescued by members of the public after four days.

A wallaby on the loose in Kentucky was caught on security camera during a nighttime visit to a Perry County family's front yard.

The Pentagon on Monday ordered all Department of Defense civilian employees to be fully vaccinated against COVID-19 by no later than Nov. 22.

SANTA CLARA, Calif. and MUNICH, Nov. 7, 2024 — Cerabyte, a pioneer of ceramic-based data storage solutions, today announced its participation at SuperComputing 2024 (SC24), taking place at the Georgia […]

The post Cerabyte Discusses Use Cases for Its Ceramic Data Storage Solution at SC24 appeared first on HPCwire.

Cameron Crowe, the writer and director behind "We Bought a Zoo," "Almost Famous" and "Jerry Maguire," has a new baby girl with girlfriend Anais Smith.

The Federal Aviation Administration has banned flights to-and-from Haiti for at least 30 days after JetBlue and Spirit Airlines planes were hit by gunfire Monday during attempts to land in Port-au-Prince.

A robot powered by artificial intelligence created an abstract portrait of Alan Turing that could sell for an estimated $180,000.

Study of women over 50 suggests how to cut dementia risk by 90 percent.

Not only does hearing this statement lower IQ, it also makes people more aggressive, other studies have shown.

A study reveals how six simple food additions could dramatically lower your dementia risk.

Which types of exercise can help keep the brain healthy?

What if solving poverty, caring for nature and fostering well-being were the ultimate goals of the economy, instead of growth for its own sake? Environmentalist and economist Gaya Herrington proposes a shift in thinking from "never enough" to "enough for each," asking us to contemplate whether the end of exponential growth on a finite planet will come by design — or disaster.

In a universe not unlike ours, a tech-environmentalist group claims to have created an AI that is the direct “voice of the earth,” a computer connected via electrodes to the mycelium network under an ancient forest named S.A.N (Sentient Advocate of Nature). The film imagines what nature thinks of human impact on the planet, as a renowned reporter conducts a world-first interview with S.A.N.

Pennsylvania Gov. Tom Wolf, a Democrat, has become increasingly critical of charter schools this year, and his new proposals for charters would change how they operate and how they are funded.

Rhode Island's Council on Elementary and Secondary Education has postponed a decision on whether school districts can charge for summer school.

Lucille Bridges, the mother of civil rights activist Ruby Bridges, who walked with her then-6-year-old daughter past crowds screaming racist slurs as she became the first Black student at her all-white New Orleans elementary school, has died at the age of 86.

Now Newark, New Jersey, is exploding, thanks to the attempts at intimidation by Governor Christie's hand-picked superintendent of schools, Cami Anderson.

The Connecticut Coalition for Achievement Now, or ConnCAN, has profiled five successful early childhood education programs in other states for ideas to help programs in Connecticut.

No place in Georgia has suffered a higher rate of coronavirus cases than Dougherty County. And the school system, largely rural and poor, is in the middle of it.

In a case involving a transgender track athlete, the Trump administration says female transgender athletes are seeking "special treatment" to compete in girls' or women's sports.

The judge said the law likely discriminates on the basis of transgender status in violation of the equal-protection clause of the U.S. Constitution.

Kenzie Lalonde will become the first woman play-by-play announcer for an NHL team's TV broadcasts in Canada. Reactions and endorsements have poured in.

Who is the best player in Penguins' history to wear #64?

The Calgary Flames' fifth game in eight nights and three time zones was a tough one they need to learn from

How did the Miami and Georgia losses impact the CFP rankings in their second release?

Tennessee won easily over Mississippi State. Indiana and BYU won nail-biters. So why did they jump over the Vols? We asked the CFP committee chair.

Academic and health offerings have increased in McDowell County, W.Va., due to a private-public partnership.

The court declined to take up an appeal backed by school groups of a ruling allowing some property taxpayers challenge their assessments in federal court.

Onward State published a story this week that contained on-the-record comments from former Marquette players about Carolyn Kieger's coaching style.

Donna M. Wilcock
May 1, 2003; 23:3745-3751
Development Plasticity Repair

Mahsa Altafi
Oct 23, 2024; 44:e0518242024-e0518242024
Systems/Circuits

Matthew F. Glasser
Aug 10, 2011; 31:11597-11616
BehavioralSystemsCognitive

The brain's extracellular matrix (ECM) regulates neuronal plasticity and animal behavior. ECM staining shows a net-like structure around a subset of neurons, a ring-like structure at the nodes of Ranvier, and diffuse staining in the interstitial matrix. However, understanding the structural features of ECM deposition across various neuronal types and subcellular compartments remains limited. To visualize the organization pattern and assembly process of the hyaluronan-scaffolded ECM in the brain, we fused a HaloTag to hyaluronan proteoglycan link protein 1, which links hyaluronan and proteoglycans. Expression or application of the probe in primary rat neuronal cultures enables us to identify spatial and temporal regulation of ECM deposition and heterogeneity in ECM aggregation among neuronal populations. Dual-color birthdating shows the ECM assembly process in culture and in vivo. Sparse expression in mouse brains of either sex reveals detailed ECM architectures around excitatory neurons and developmentally regulated dendritic ECM. Our study uncovers extensive structural features of the brain's ECM, suggesting diverse roles in regulating neuronal plasticity.

Neural circuits supporting innate behaviors, such as feeding, exploration, and social interaction, intermingle in the lateral hypothalamus (LH). Although previous studies have shown that individual LH neurons change their firing relative to the baseline during one or more behaviors, the firing rate dynamics of LH populations within behavioral episodes and the coordination of behavior-related LH populations remain largely unknown. Here, using unsupervised graph-based clustering of LH neurons firing rate dynamics in freely behaving male mice, we identified distinct populations of cells whose activity corresponds to feeding, specific times during feeding bouts, or other innate behaviors—social interaction and novel object exploration. Feeding-related cells fired together with a higher probability during slow and fast gamma oscillations (30–60 and 60–90 Hz) than during nonrhythmic epochs. In contrast, the cofiring of neurons signaling other behaviors than feeding was overall similar between slow gamma and nonrhythmic epochs but increased during fast gamma oscillations. These results reveal a neural organization of ethological hierarchies in the LH and point to behavior-specific motivational systems, the dysfunction of which may contribute to mental disorders.

Aggression involves both sexually monomorphic and dimorphic actions. How the brain implements these two types of actions is poorly understood. We found that in Drosophila melanogaster, a set of neurons, which we call CL062, previously shown to mediate male aggression also mediate female aggression. These neurons elicit aggression acutely and without the presence of a target. Although the same set of actions is elicited in males and females, the overall behavior is sexually dimorphic. The CL062 neurons do not express fruitless, a gene required for sexual dimorphism in flies, and expressed by most other neurons important for controlling fly aggression. Connectomic analysis in a female electron microscopy dataset suggests that these neurons have limited connections with fruitless expressing neurons that have been shown to be important for aggression and signal to different descending neurons. Thus, CL062 is part of a monomorphic circuit for aggression that functions parallel to the known dimorphic circuits.

A statement by FAO Director-General QU Dongyu

The UN Food Systems Summit +2 Stocktaking Moment, taking place in Rome, Italy, from 24-26 July, will build on the momentum of the 2021 Food Systems Summit and [...]

Transitions: Photographs by Robert Creamer

Megan Leftwich, an engineering professor at George Washington University, is building a robotic flipper based on her observations of sea lions