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The Declaration of Independence

Hear the words that were catalyst to the Revolution, read by Bill Barker, Colonial Williamsburg's Thomas Jefferson.




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Backstory Radio Presents: The American Indian Story

In October 2010, the hosts of Backstory visited Colonial Williamsburg's Kimball Theatre to perform a live show.




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Formation and disappearance of aldehydes during simulated gastrointestinal digestion of fried clams

Food Funct., 2020, 11,3483-3492
DOI: 10.1039/C9FO03021B, Paper
Zhong-Yuan Liu, Yuan-Yuan Hu, Man-Tong Zhao, Hong-Kai Xie, Xiao-Pei Hu, Xiao-Chi Ma, Jiang-Hua Zhang, Yan-Hong Bai, Da-Yong Zhou
The formation and disappearance of aldehydes during simulated gastrointestinal digestion (SD) of fried clams was investigated in order to shed light on the underlying mechanism.
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Supplementation of nano-bubble curcumin extract improves gut microbiota composition and exercise performance in mice

Food Funct., 2020, 11,3574-3584
DOI: 10.1039/C9FO02487E, Paper
Yi-Ming Chen, Wan-Chun Chiu, Yen-Shuo Chiu, Tong Li, Hsin-Ching Sung, Chien-Yu Hsiao
NCE supplementation was able to modulate the gut microbiota increased the Lactobacillus genus.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Fucoxanthin alleviates palmitate-induced inflammation in RAW 264.7 cells through improving lipid metabolism and attenuating mitochondrial dysfunction

Food Funct., 2020, 11,3361-3370
DOI: 10.1039/D0FO00442A, Paper
Siyu Li, Xiaomeng Ren, Yuandong Wang, Jiangning Hu, Haitao Wu, Shuang Song, Chunhong Yan
Fucoxanthin mitigated palmitate-induced inflammation in macrophages through promoting fatty acid oxidation and ameliorating mitochondrial dysfunction.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Bilberry anthocyanin extracts enhance anti-PD-L1 efficiency by modulating gut microbiota

Food Funct., 2020, 11,3180-3190
DOI: 10.1039/D0FO00255K, Paper
Luoyang Wang, Guoqiang Jiang, Nan Jing, Xuerun Liu, Qicheng Li, Wei Liang, Zheng Liu
Bilberry anthocyanin extracts change the gut microbiota and enhance the anti-tumor efficiency of the PD-L1 antibody.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Vinegar extract ameliorates alcohol-induced liver damage associated with the modulation of gut microbiota in mice

Food Funct., 2020, 11,2898-2909
DOI: 10.1039/C9FO03015H, Paper
Ting Xia, Bo Zhang, Shaopeng Li, Bin Fang, Wenhui Duan, Jin Zhang, Jia Song, Min Wang
Vinegar extract inhibited alcohol-induced ROS generation and inflammation. Vinegar extract modulated gut microbiota and improved intestinal homeostasis, which could be used as a novel gut microbiota manipulator against alcohol-induced liver damage.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Capsaicin—the major bioactive ingredient of chili peppers: bio-efficacy and delivery systems

Food Funct., 2020, 11,2848-2860
DOI: 10.1039/D0FO00351D, Review Article
Muwen Lu, Chengyu Chen, Yaqi Lan, Jie Xiao, Run Li, Junqing Huang, Qingrong Huang, Yong Cao, Chi-Tang Ho
The mechanisms of bio-efficacy of capsaicin and delivery systems with enhanced bioavailability were reviewed.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Seaweed Porphyra yezoensis polysaccharides with different molecular weights inhibit hydroxyapatite damage and osteoblast differentiation of A7R5 cells

Food Funct., 2020, 11,3393-3409
DOI: 10.1039/C9FO01732A, Paper
Ling-Hong Huang, Hong Liu, Jia-Yun Chen, Xin-Yuan Sun, Zhi-hui Yao, Jin Han, Jian-Ming Ouyang
Porphyra yezoensis polysaccharide could effectively reduce the cell damage and osteogenic transformation of vascular smooth muscle cells induced by hydroxyapatite crystals.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Untargeted metabolomics revealed therapeutic mechanisms of icariin on low bone mineral density in older caged laying hens

Food Funct., 2020, 11,3201-3212
DOI: 10.1039/C9FO02882J, Paper
Jie Huang, Yanping Hu, Xiaofeng Tong, Lei Zhang, Zhengwang Yu, Zhongxin Zhou
Untargeted metabolomics revealed the therapeutic effects and mechanisms of icariin on low bone mineral density in older caged laying hens.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Tilapia head glycolipids reduce inflammation by regulating the gut microbiota in dextran sulphate sodium-induced colitis mice

Food Funct., 2020, 11,3245-3255
DOI: 10.1039/D0FO00116C, Paper
Zhipeng Gu, Yujie Zhu, Shuaiming Jiang, Guanghua Xia, Chuan Li, Xueying Zhang, Jiachao Zhang, Xuanri Shen
Tilapia head glycolipids reduce inflammation by regulating the gut microbiota in dextran sulphate sodium-induced colitis mice.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Girinimbine from curry leaves promotes gastro protection against ethanol induced peptic ulcers and improves healing via regulation of anti-inflammatory and antioxidant mechanisms

Food Funct., 2020, 11,3493-3505
DOI: 10.1039/D0FO00053A, Paper
Syam Mohan, Yahya Hasan Hobani, Emad Shaheen, Alaa Sayed Abou-Elhamd, Aymen abdelhaleem, Hassan A. Alhazmi, Siddig Ibrahim Abdelwahab
Curry leaves (Murraya koenigii) are a leafy spice used in Indian cookery for its fragrant aroma.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Preparation of theasinensin A and theasinensin B and exploration of their inhibitory mechanism on α-glucosidase

Food Funct., 2020, 11,3527-3538
DOI: 10.1039/C9FO03054A, Paper
Sainan Tao, Guijie Chen, Weiqi Xu, Yujia Peng, Peng Wan, Yi Sun, Xiaoxiong Zeng, Zhonghua Liu
Theasinensin A (TSA) and theasinensin B (TSB), dimers of tea catechins produced during the processing of oolong tea and black tea, had superior inhibitory effects on α-glucosidase.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Ethanolamides of essential α-linolenic and linoleic fatty acids suppress short-term food intake in rats

Food Funct., 2020, 11,3066-3072
DOI: 10.1039/C9FO02884F, Paper
Mandy Ho, G. Harvey Anderson, Lin Lin, Richard P. Bazinet, Ruslan Kubant
α-Linolenoylethanolamide and linoleoylethanolamide suppress short-term food intake in rats.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Purification, characterization and molecular cloning of a dicaffeoylquinic acid-hydrolyzing esterase from human-derived Lactobacillus fermentum LF-12

Food Funct., 2020, 11,3235-3244
DOI: 10.1039/D0FO00029A, Paper
Yujin Liu, Minhao Xie, Peng Wan, Guijie Chen, Chunxu Chen, Dan Chen, Shijie Yu, Xiaoxiong Zeng, Yi Sun
Dicaffeoylquinic acids (DiCQAs), the main components of kudingcha made from the leaves of Ilex kudingcha, could be transformed by gut microbiota.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Low-dose ethanol intake prevents high-fat diet-induced adverse cardiovascular events in mice

Food Funct., 2020, 11,3549-3562
DOI: 10.1039/C9FO02645B, Paper
Junhui Nie, Linel Darrel Ngokana, Jiayuan Kou, Yuchen Zhao, Jiajie Tu, Heng Ji, Peizhu Tan, Tingting Zhao, Yuwei Cao, Zhaojing Wu, Qi Wang, Shuangfeng Ren, Xiuchen Xuan, Hui Huang, Yanze Li, Huan Liang, Xu Gao, Lingyun Zhou
This study aimed to clarify whether low-dose ethanol intake could prevent high-fat diet-induced adverse effects on cardiomyocytes in mice.
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The prophylactic effects of different Lactobacilli on collagen-induced arthritis in rats

Food Funct., 2020, 11,3681-3694
DOI: 10.1039/C9FO02556A, Paper
Zhexin Fan, Bo Yang, R. Paul Ross, Catherine Stanton, Jianxin Zhao, Hao Zhang, Wei Chen
The current study evaluated the prophylactic effects of different Lactobacillus species on arthritis induced by collagen.
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Oleacein inhibits STAT3, activates the apoptotic machinery, and exerts anti-metastatic effects in the SH-SY5Y human neuroblastoma cells

Food Funct., 2020, 11,3271-3279
DOI: 10.1039/D0FO00089B, Paper
Santa Cirmi, Marilena Celano, Giovanni Enrico Lombardo, Valentina Maggisano, Antonio Procopio, Diego Russo, Michele Navarra
The present findings demonstrate that oleacein, the main secoiridoid of extravirgin olive oil, acts against neuroblastoma cells, by reducing cell adhesion and migration, inducing apoptotic death and modulating STAT3-dependent pathway.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Inducing secondary structural interplays between scallop muscle proteins and soy proteins to form soluble composites

Food Funct., 2020, 11,3351-3360
DOI: 10.1039/C9FO03106E, Paper
Chao Wu, Jiamei Wang, Xiaokang Na, Zhenyu Wang, Xianbing Xu, Tao Wang
Scallop muscle proteins and soya proteins were packed into a composite with tunable internal, molecular arrangements of the secondary structures.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Quantifying dietary vitamin K and its link to cardiovascular health: a narrative review

Food Funct., 2020, 11,2826-2837
DOI: 10.1039/C9FO02321F, Review Article
Claire R. Palmer, Lauren C. Blekkenhorst, Joshua R. Lewis, Natalie C. Ward, Carl J. Schultz, Jonathan M. Hodgson, Kevin D. Croft, Marc Sim
Potential beneficial pathways by which vitamin K may reduce the risk of cardiovascular disease mortality.
The content of this RSS Feed (c) The Royal Society of Chemistry




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DHA substitution overcomes high-fat diet-induced disturbance in the circadian rhythm of lipid metabolism

Food Funct., 2020, 11,3621-3631
DOI: 10.1039/C9FO02606A, Paper
Rulong Chen, Zhengyu Zuo, Qi Li, Hualin Wang, Na Li, Hongyu Zhang, Xiaoli Yu, Zhiguo Liu
DHA substitution overcomes high-fat diet-induced disturbance in the circadian rhythm of lipid metabolism via the core gene Clock/Bmal1 controlled circadian nuclear receptor pathway.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Colonization and immunoregulation of Lactobacillus plantarum BF_15, a novel probiotic strain from the feces of breast-fed infants

Food Funct., 2020, 11,3156-3166
DOI: 10.1039/C9FO02745A, Paper
Na Zhang, Chen Li, Zhihua Niu, Hongyan Kang, Miaoshu Wang, Bo Zhang, Hongtao Tian
Immunosuppression is a manifestation imbalance in the immune system, often during unhealthy states.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Protocatechuic acid and quercetin glucosides in onions attenuate changes induced by high fat diet in rats

Food Funct., 2020, 11,3585-3597
DOI: 10.1039/C9FO02633A, Paper
Katarzyna Grzelak-Błaszczyk, Joanna Milala, Krzysztof Kołodziejczyk, Michał Sójka, Andrzej Czarnecki, Monika Kosmala, Robert Klewicki, Bartosz Fotschki, Adam Jurgoński, Jerzy Juśkiewicz
Yellow onion waste from industrial peeling was used to obtain three pure preparations: protocatechuic acid (PA), quercetin diglycosides (QD) and quercetin monoglycosides (QM).
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Integrated anti-hyperlipidemic bioactivity of whole Citrus grandis [L.] osbeck fruits—multi-action mechanism evidenced using animal and cell models

Food Funct., 2020, 11,2978-2996
DOI: 10.1039/C9FO02290B, Paper
Li-Yun Lin, Boa-Chan Huang, Kuan-Chou Chen, Robert Y. Peng
Multi- antihyperlipidemic mechanism revealed by the pomelo phytonutrients. Both the sterol synthesis and lipogenesis pathways are affected by the pomelo phytonutrients. Dotted line: from citation. Solid line: verified in this experiment.
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Ptaquiloside from bracken (Pteridium spp.) promotes oral carcinogenesis initiated by HPV16 in transgenic mice

Food Funct., 2020, 11,3298-3305
DOI: 10.1039/D0FO00207K, Paper
Rui M. Gil da Costa, Tiago Neto, Diogo Estêvão, Magda Moutinho, Ana Félix, Rui Medeiros, Carlos Lopes, Margarida M. S. M. Bastos, Paula A. Oliveira
Bracken (Pteridium spp.) is a common weed that is consumed as food especially in Asia, and is suspected of promoting carcinogenesis induced by papillomaviruses in the digestive and urinary systems.
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Proteomic landscape of liver tissue in old male mice that are long-term treated with polysaccharides from Sargassum fusiforme

Food Funct., 2020, 11,3632-3644
DOI: 10.1039/D0FO00187B, Paper
Peichao Chen, Ya Zhang, Man Xu, Hongjun Chen, Huixi Zou, Xu Zhang, Haibin Tong, Cuiping You, Mingjiang Wu
The polysaccharides extracted from Sargassum fusiforme delays the aging process via mitochondria-associated anti-oxidation.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Chronic flavanol-rich cocoa powder supplementation reduces body fat mass in endurance athletes by modifying the follistatin/myostatin ratio and leptin levels

Food Funct., 2020, 11,3441-3450
DOI: 10.1039/D0FO00246A, Paper
Jose Ángel García-Merino, Diego Moreno-Pérez, Beatriz de Lucas, Maria Gregoria Montalvo-Lominchar, Elsa Muñoz, Lara Sánchez, Fernando Naclerio, Karen Marlene Herrera-Rocha, Martha Rocío Moreno-Jiménez, Nuria Elisabeth Rocha-Guzmán, Mar Larrosa
Flavanols-rich cocoa reduced body fat composition in athletes through modulation of follistatin and leptin levels.
The content of this RSS Feed (c) The Royal Society of Chemistry




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The effect of culinary doses of spices in a high-saturated fat, high-carbohydrate meal on postprandial lipemia and endothelial function: a randomized, controlled, crossover pilot trial

Food Funct., 2020, 11,3191-3200
DOI: 10.1039/C9FO02438G, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Kristina S. Petersen, Connie J. Rogers, Sheila G. West, David N. Proctor, Penny M. Kris-Etherton
Lower doses of spices (2 and 6 g) than previously tested may attenuate postprandial lipemia and impairments in endothelial function caused by a high-saturated fat, high-carbohydrate meal.
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Addition of flavonols and polysaccharides as excipient ingredients into epicatechin rich green tea extract inhibited free radical formation and glucose uptake

Food Funct., 2020, 11,3105-3111
DOI: 10.1039/C9FO03020D, Paper
So-Hee Yoo, Yeong-Eun Lee, Jin-Oh Chung, Chan-Su Rha, Yong-Deog Hong, Mi-Young Park, Soon-Mi Shim
Results from the current study suggested that whole green tea components rich in flavonols and polysaccharides could be potential hypoglycemic excipient ingredients into green tea catechins by enhancing catechin absorption.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Whole-wheat flour particle size influences dough properties, bread structure and in vitro starch digestibility

Food Funct., 2020, 11,3610-3620
DOI: 10.1039/C9FO02587A, Paper
Suyun Lin, Jing Gao, Xiaoxuan Jin, Yong Wang, Zhizhong Dong, Jian Ying, Weibiao Zhou
Whole-wheat flour (WWF) particle size is critical to dough properties, bread quality, and in vitro starch digestibility of bread.
The content of this RSS Feed (c) The Royal Society of Chemistry




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cis 9, trans 11, but not trans 10, cis 12 CLA isomer, impairs intestinal epithelial barrier function in IPEC-J2 cells and mice through activation of GPR120-[Ca2+]i and the MLCK signaling pathway

Food Funct., 2020, 11,3657-3667
DOI: 10.1039/D0FO00376J, Paper
Han Su, Weijie Zhao, Fenglin Zhang, Min Song, Fangfang Liu, Jisong Zheng, Mingfa Ling, Xiaohua Yang, Qiang Yang, Haiwen He, Lin Chen, Xumin Lai, Xiaotong Zhu, Lina Wang, Ping Gao, Gang Shu, Qingyan Jiang, Songbo Wang
In vitro and in vivo studies show that c9, t11-CLA, but not t10, c12-CLA isomer, impairs intestinal epithelial barrier function in IPEC-J2 cells and mice via activation of GPR120-[Ca2+]i and the MLCK pathway.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Cloning, expression and comparison of the properties of Scy p 9, a Scylla paramamosain allergen

Food Funct., 2020, 11,3006-3019
DOI: 10.1039/D0FO00004C, Paper
Xin-Rong He, Yi-Meng Cheng, Yang Yang, Jie-Jing Xie, Ka-Hou Chu, Yong-Xia Zhang, Gui-Xia Chen, Hong Liu, Min-Jie Cao, Guang-Ming Liu
This study investigated the properties of Scy p 9 in mud crab (Scylla paramamosain).
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Black mulberry ethanol extract attenuates atherosclerosis-related inflammatory factors and downregulates PPARγ and CD36 genes in experimental atherosclerotic rats

Food Funct., 2020, 11,2997-3005
DOI: 10.1039/C9FO02736J, Paper
Yun-Guo Liu, Jia-Li Yan, Yan-Qing Ji, Wen-Jing Nie, Yan Jiang
Atherosclerosis (AS) is the pathological basis of various vascular diseases and currently is seriously affecting human health.
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Dietary intake of Lycium ruthenicum Murray ethanol extract inhibits colonic inflammation in dextran sulfate sodium-induced murine experimental colitis

Food Funct., 2020, 11,2924-2937
DOI: 10.1039/D0FO00172D, Paper
Shuai Zong, Liu Yang, Hyun Jin Park, Jinglei Li
Lycium ruthenicum Murray extract protected experimental colitis by inhibiting pro-inflammatory cytokines production, inflammatory cell infiltration, inflammatory mediators activation and oxidative stress, and restored intestinal barrier integrity.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Metallic iron in cornflakes

Food Funct., 2020, 11,2938-2942
DOI: 10.1039/C9FO02370D, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Frederik Lermyte, Wen-Ying Zhang, Jake Brooks, Steven Huband, Joanna F. Collingwood, Martin R. Lees, Margaret P. Rayman, Peter J. Sadler
Magnetometry and X-ray analysis show that the iron in cornflake-style cereals fortified with this essential element at levels up to 14 mg per 100 g, is micron-sized body-centred cubic metallic iron, partially soluble at stomach pH.
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The impact of oligosaccharide content, glycosidic linkages and lactose content of galacto-oligosaccharides (GOS) on the expression of mucus-related genes in goblet cells

Food Funct., 2020, 11,3506-3515
DOI: 10.1039/D0FO00064G, Paper
Susana Figueroa-Lozano, Chengcheng Ren, Huifang Yin, Hien Pham, Sander van Leeuwen, Lubbert Dijkhuizen, Paul de Vos
Galacto-oligosaccharides (GOS) are molecules known to impact goblet cell function and mucus composition. Our results show that their molecular structure have a direct effect on goblet cells and impact mucus synthesis-related genes.
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Molecular mechanisms of selenium-biofortified soybean protein and polyphenol conjugates in protecting mouse skin damaged by UV-B

Food Funct., 2020, 11,3563-3573
DOI: 10.1039/C9FO02560J, Paper
Xing Zhang, Hui He, Tao Hou
A new selenium-biofortified protein and polyphenol conjugate with high antioxidant activity and stability for the treatment of photooxidation-related diseases.
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Correction: 5-Heptadecylresorcinol attenuates oxidative damage and mitochondria-mediated apoptosis through activation of the SIRT3/FOXO3a signaling pathway in neurocytes

Food Funct., 2020, 11,3749-3749
DOI: 10.1039/D0FO90012E, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Jie Liu, Yu Wang, Yiming Hao, Zongwei Wang, Zihui Yang, Ziyuan Wang, Jing Wang
The content of this RSS Feed (c) The Royal Society of Chemistry




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Lycium barbarum polysaccharides ameliorate intestinal barrier dysfunction and inflammation through the MLCK-MLC signaling pathway in Caco-2 cells

Food Funct., 2020, 11,3741-3748
DOI: 10.1039/D0FO00030B, Paper
Wei Li, Mingbo Gao, Ting Han
Impairment of the intestinal barrier often occurs in inflammatory bowel diseases, and pro-inflammatory factors play a vital role in the pathogenesis of intestinal diseases.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Cherry stem infusions: antioxidant potential and phenolic profile by UHPLC-ESI-QTOF-MS

Food Funct., 2020, 11,3471-3482
DOI: 10.1039/C9FO02693B, Paper
Juliana Peixoto, Gerardo Álvarez-Rivera, Rita C. Alves, Anabela S. G. Costa, Nelson Andrade, Andreia Moreira, Alejandro Cifuentes, Fátima Martel, M. Beatriz P. P. Oliveira, Elena Ibáñez
This study highlights not only the antioxidant potential of cherry stem infusion but also the need to globally harmonize the control and regulation of herbal products.
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Correction: Matrix-mediated distribution of 4-hydroxy-2-hexanal (nonenal) during deep-frying of chicken breast and potato sticks in vegetable oil

Food Funct., 2020, 11,3750-3750
DOI: 10.1039/D0FO90018D, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Lukai Ma, Guoqin Liu, Weiwei Cheng, Xinqi Liu, Huifan Liu, Qin Wang
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Dietary intakes of flavonoids and carotenoids and the risk of developing an unhealthy metabolic phenotype

Food Funct., 2020, 11,3451-3458
DOI: 10.1039/C9FO02852H, Paper
Nazanin Moslehi, Mahdieh Golzarand, Farhad Hosseinpanah, Parvin Mirmiran, Fereidoun Azizi
This study was designed to investigate prospective associations between dietary habitual intakes of flavonoids and carotenoids and the development of an unhealthy metabolic phenotype separately in normal-weight and excess weight individuals.
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Hot-water extract of ripened Pu-erh tea attenuates DSS-induced colitis through modulation of the NF-κB and HIF-1α signaling pathways in mice

Food Funct., 2020, 11,3459-3470
DOI: 10.1039/C9FO02803J, Paper
Yina Huang, Liang Qiu, Xuan Mi, Zhihong Zhang, Di Xu, Xueying Tao, Keyu Xing, Qinglong Wu, Hua Wei
There was lots of information on anti-obesity and reduced risk of cardiovascular disease, to our best knowledge, little was known about the prevention of colitis by RPT. We firstly assessed effects of RPT on phenotypic improvements of DSS-induced colitis in mice.
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Gut microbiota mediate the protective effects on endometritis induced by Staphylococcus aureus in mice

Food Funct., 2020, 11,3695-3705
DOI: 10.1039/C9FO02963J, Paper
Xiaoyu Hu, Ruiying Mu, Mingyue Xu, Xin Yuan, Peng Jiang, Jian Guo, Yongguo Cao, Naisheng Zhang, Yunhe Fu
Endometritis, the inflammation of the endometrial lining caused by bacterial pathogens, is associated with reproductive failure.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Inflammation and cardiovascular disease: are marine phospholipids the answer?

Food Funct., 2020, 11,2861-2885
DOI: 10.1039/C9FO01742A, Review Article
Ronan Lordan, Shane Redfern, Alexandros Tsoupras, Ioannis Zabetakis
This review presents the latest research on the cardioprotective effects of n-3 fatty acids (FA) and n-3 FA bound to polar lipids (PL). Overall, n-3 PL may have enhanced bioavailability and potentially bioactivity versus free FA and ester forms of n-3 FA.
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Potential neurotoxicity of 5-hydroxymethylfurfural and its oligomers: widespread substances in carbohydrate-containing foods

Food Funct., 2020, Advance Article
DOI: 10.1039/C9FO02526J, Paper
Cheng Wang, Zhenru Liu, Tian Hu, Youjia Li, Rui Liu, Junjie Zhang, Huaizhen He
5-Hydroxymethylfurfural (5-HMF) and its acid-catalyzed oligomers can inhibit nerve cell proliferation and induce neurological deficits at near or below the reported 24 h dietary intake of 5-HMF in humans.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Alleviating effects of noni fruit polysaccharide on hepatic oxidative stress and inflammation in rats under a high-fat diet and its possible mechanisms

Food Funct., 2020, 11,2953-2968
DOI: 10.1039/D0FO00178C, Paper
Xiaobing Yang, Wenjing Mo, Chuanjin Zheng, Wenzhi Li, Jian Tang, Xiaoyong Wu
Non-alcoholic fatty liver disease is associated with gut microbiota, oxidative stress, and inflammation.
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Ergosterol peroxide from Pleurotus ferulae inhibits gastrointestinal tumor cell growth through induction of apoptosis via reactive oxygen species and endoplasmic reticulum stress

Food Funct., 2020, Advance Article
DOI: 10.1039/C9FO02454A, Paper
Yi Yang, Xiaoyu Luo, Mayila Yasheng, Jun Zhao, Jinyu Li, Jinyao Li
Ergosterol peroxide was purified from Pleurotus ferulae by silica gel chromatography, Sephadex LH-20 chromatography and recrystallization and named as PFEP, which was identified by ESI-MS and NMR.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Flavonoids isolated from loquat (Eriobotrya japonica) leaves inhibit oxidative stress and inflammation induced by cigarette smoke in COPD mice: the role of TRPV1 signaling pathways

Food Funct., 2020, 11,3516-3526
DOI: 10.1039/C9FO02921D, Paper
Tunyu Jian, Jian Chen, Xiaoqin Ding, Han Lv, Jiawei Li, Yuexian Wu, Bingru Ren, Bei Tong, Yuanyuan Zuo, Kelei Su, Weilin Li
Total flavonoids isolated from loquat leaves inhibit inflammation and oxidative stress by regulating TRPV1 and the related pathway in cigarette smoke-induced COPD mice.
The content of this RSS Feed (c) The Royal Society of Chemistry