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Review article: Understanding change and continuity in India’s foreign policy

6 January 2017 , Volume 93, Number 1

Aseema Sinha

The field of Indian foreign policy is rich and wide ranging, offering new empirical material across a broad array of topics and relationships. This article reviews three recent books on the subject, with an eye towards evaluating change amid continuity in the pursuit of Indian foreign policy. This scholarship calls out for a new paradigm to understand India’s changing position and actions at global, regional and domestic levels. I argue that Indian foreign policy can and should be seen through the prism of an open border, interdependence framework, wherein both the domestic and global levels are analysed in a linked manner. While the literature surveyed here does not yet offer a new paradigm, some common findings suggest the need for new approaches. We also need to find and use new sources of data and seek ways to measure institutional effects in foreign policy. The task of measurement and theoretical modelling is made more challenging by the need to theorize the linkages across levels and to measure foreign policy variables in different countries simultaneously.




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Meet the Ohio health expert who has a fan club — and Republicans trying to stop her

Some Buckeyes are not comfortable being told by a "woman in power" to quarantine, one expert said.





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As many as 75,000 could die from "deaths of despair" as a result of the coronavirus pandemic. One expert says economic turmoil has always led to an increase in suicides.

"I think it's always important to think about suicide as individual vulnerabilities and context," Eric Caine said.





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China reports first coronavirus case in Wuhan since April 3 among 14 new infections

China's National Health Commission reported 14 new confirmed coronavirus cases on May 9, the highest number since April 28, including the first for more than a month in the city of Wuhan where the outbreak was first detected late last year. While China had officially designated all areas of the country as low-risk last Thursday, the new cases according to data published on Sunday represent a jump from the single case reported for the day before. The new Wuhan case, the first reported in the epicentre of China's outbreak since April 3, was previously asymptomatic, according to the health commission.





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Tripoli airport shelling hits fuel tanks, passenger plane-ministry

Shelling of Tripoli's Mitiga airport early on Saturday, part of an intensified barrage of artillery fire on the capital in recent days, hit fuel tanks and damaged passenger planes, the Transport Ministry said in a statement. Mitiga is the last functioning airport in the Libyan capital, though civilian flights stopped in March because of repeated shelling even before the country imposed a lockdown over the coronavirus pandemic. Brega Petroleum Marketing Company, part of the National Oil Corporation, said its jet fuel tanks at Mitiga caught fire after coming under attack and firemen were working to control the blaze.





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A photographer spent two weeks flying around in helicopters to capture the parked planes at US airports during the pandemic — see his eerie and beautiful work

Travel blogger and photographer Andy Luten drove 4,200 miles across six states to see the grounded jets, detailing the shocking state of aviation.





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Inhibition of glycosphingolipid biosynthesis reverts multidrug resistance by differentially modulating ABC transporters in chronic myeloid leukemias [Cell Biology]

Multidrug resistance (MDR) in cancer arises from cross-resistance to structurally- and functionally-divergent chemotherapeutic drugs. In particular, MDR is characterized by increased expression and activity of ATP-binding cassette (ABC) superfamily transporters. Sphingolipids are substrates of ABC proteins in cell signaling, membrane biosynthesis, and inflammation, for example, and their products can favor cancer progression. Glucosylceramide (GlcCer) is a ubiquitous glycosphingolipid (GSL) generated by glucosylceramide synthase, a key regulatory enzyme encoded by the UDP-glucose ceramide glucosyltransferase (UGCG) gene. Stressed cells increase de novo biosynthesis of ceramides, which return to sub-toxic levels after UGCG mediates incorporation into GlcCer. Given that cancer cells seem to mobilize UGCG and have increased GSL content for ceramide clearance, which ultimately contributes to chemotherapy failure, here we investigated how inhibition of GSL biosynthesis affects the MDR phenotype of chronic myeloid leukemias. We found that MDR is associated with higher UGCG expression and with a complex GSL profile. UGCG inhibition with the ceramide analog d-threo-1-(3,4,-ethylenedioxy)phenyl-2-palmitoylamino-3-pyrrolidino-1-propanol (EtDO-P4) greatly reduced GSL and monosialotetrahexosylganglioside levels, and co-treatment with standard chemotherapeutics sensitized cells to mitochondrial membrane potential loss and apoptosis. ABC subfamily B member 1 (ABCB1) expression was reduced, and ABCC-mediated efflux activity was modulated by competition with nonglycosylated ceramides. Consistently, inhibition of ABCC-mediated transport reduced the efflux of exogenous C6-ceramide. Overall, UGCG inhibition impaired the malignant glycophenotype of MDR leukemias, which typically overcomes drug resistance through distinct mechanisms. This work sheds light on the involvement of GSL in chemotherapy failure, and its findings suggest that targeted GSL modulation could help manage MDR leukemias.




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Classifying deaths from COVID-19: Why the official statistics will never reflect the true mortality from coronavirus, and how future studies could try to address this




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The multi-ness of fighting the short-term and long-term consequences of the COVID-19 pandemic




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Re: Covid-19: Brazil’s president rallies supporters against social distancing




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A real opportunity to improve neurology services in England




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US drug costs are rising faster than overall health spending, officials report




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Cancer Drugs Fund requires further reform




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Opportunities for Transatlantic Cooperation on International Migration

The EU-U.S. relationship is one of the most significant partnerships among wealthy nations. Interconnections between the two on migration issues make dialogue necessary and inevitable, as each relies on each other to attain a number of policy objectives, most clearly in the case of travel and border security.




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The Economic Integration of Immigrants in the United States: Long- and Short-Term Perspectives

The United States has historically offered unparalleled economic opportunity to successive generations of immigrants and their children, poised to play an increasing role in the U.S. economy. But the lasting impact of job loss and slower growth over the next decade will translate into fewer opportunities for workers—and immigrants may prove the most vulnerable.




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Shared Challenges and Opportunities for EU and U.S. Immigration Policymakers

This final report summarizes and reflects upon the key findings of the Improving EU and U.S. Immigration Systems: Learning from Experience comparative research project undertaken by MPI and the European University Institute through a grant from the European Commission.




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Breakenridge eyeing three in a row for Portmore

While many Red Stripe Premier League (RSPL) players are finding it very difficult to stay motivated and maintain their training regime until the league is able to restart, Portmore defender Romaine Breakenridge remains highly motivated and eager...




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Cricket legend Murray warns against hasty restart

BRIDGETOWN, Barbados (CMC): Former top West Indies cricket administrator, 76-year-old Deryck Murray, has warned against a forced restart of cricket amid the current challenges posed by the deadly coronavirus pandemic, and says any premature actions...




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#JamaicaTogether | Portia Simpson Miller

As daunting as this COVID-19 pandemic has proven to be, and as devastating as its impact is on people both here at home and around the world, we must stand together, united. We must all act with purpose, resolve, love and compassion because when we...




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Andrews: We’ve never been approached for registration - Chairman says staff hurt by Fearon tragedy; ministry moving to certify 17 facilities

Declaring it has been “pained” by the Jodian Fearon situation, the embattled Andrews Memorial Hospital (AMH) is speaking out, saying it has never been approached for or rejected efforts at registration or certification since it began operating 76...




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Queen of foster care - Supermom Mama Sweetie opens big heart to more than 40 children

To say Judith-Miranda Townsend has a special love for children would not even begin to capture the essence of the Westmoreland supermom. Affectionately called ‘Mama Sweetie’ by foster children and members of the Holly Hill community in Darliston,...




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Costly no-shows - Cancellation of major entertainment events could have $10b impact

Losses within the entertainment industry are already estimated to be in the billions as the sector continues to reel from the impacts of COVID-19. Major events like Reggae Sumfest, which has already been cancelled this year, had an estimated...




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Five-year INDECOM Act inertia - Williams, Golding still want prosecutorial powers for commission; DPP, Chuck, cops not sold on idea

Almost five years ago, lawmakers on a bipartisan committee of Parliament agreed unanimously to amend the law to give the Independent Commission of Investigations (INDECOM) the power to arrest and prosecute cops. That proposed amendment, which was...




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10 takeaways from the worst jobs report in US history

Brutal. Horrific. Tragic. Choose your ­description. The April jobs report showed, in harrowing ­detail, just how terribly the coronavirus outbreak has pummelled the United States economy. Most obviously, there’s the 14.7 per cent unemployment rate...




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GAP wants to delay capital projects at local airports

The operator Jamaica’s two largest airports wants to scrap or delay non-essential capital projects. It forms part of a wider halt of capital projects by the Grupo Aeroportuario del Pacífico – which translate to Pacific Airport Group, or GAP –...




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Trinidad to start reopening Tuesday, but borders to remain closed until June

(CMC): Trinidad and Tobago says its borders are to remain closed until June, even as it embarks on softening restrictions to re energise the economy, which had been halted by COVID-19.   Prime Minister Dr Keith Rowley said the...




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Teachers will need psycho-social support post COVID-19

Education officials across the Caribbean and Latin America have asserted that teachers will be in need of psycho-social support for their return to the classroom, following the COVID-19 pandemic. Approximately 91,710 teachers and seven million...




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Diasporas: New Partners in Global Development Policy

This edited volume examines the development impact of diasporas in six critical areas: entrepreneurship, capital markets, "nostalgia" trade and "heritage" tourism, philanthropy, volunteerism, and advocacy.




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Hoja de ruta para la participación de las diásporas en el desarrollo: Un manual para políticos y profesionales de los países de origen y de acogida

Este manual ofrece a los formuladores de políticas y especialistas una guía accesible y práctica sobre las iniciativas gubernamentales referentes a la diáspora. Este manual contiene un menú, seleccionado cuidadosamente, de opciones normativas y programáticas viables basadas en experiencias reales en distintas partes del mundo.




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Federal Update: A Conversation on Language Access with the U.S. Department of Justice

This MPI webinar features U.S. Department of Justice (DOJ) officials discussing the department’s efforts to improve communications with Limited English Proficient (LEP) communities in federal and federally-funded programs and activities.




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Federal Update: A Conversation on Language Access with the U.S. Department of Justice

This MPI webinar features U.S. Department of Justice (DOJ) officials discussing the department’s efforts to improve communications with Limited English Proficient (LEP) communities in federal and federally-funded programs and activities.




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Does Low-Skilled Immigration Hurt the U.S. Economy? Assessing the Evidence

In a report by MPI's Labor Markets Initiative, noted economist and Georgetown University Public Policy Institute Professor Harry J. Holzer examines the economic reasoning and research on these questions and looks at the policy options that shape the impact of less-skilled immigration on the economy. The discussion is on what policy reform would best serve native-born American workers, consumers, and employers, as well as the overall U.S. economy.




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How the Zika virus causes birth defects

New research provides the first direct evidence that Zika virus causes severe birth defects, and explains exactly how it does so

“I lifted up my T-shirt to check on what I thought had just been a small heat rash,” writes BuzzFeed correspondent Ali Watkins. “It had shown up along the right of my back, extending out from a handful of mosquito bites I had picked up… it had seemed relatively tame [but] now, it was inching across the front of my stomach and down my legs... Meanwhile, my right eye was inflamed and bright red, almost akin to a busted blood vessel.”

Watkins is describing the symptoms of a Zika virus infection that she contracted on a recent trip to Mexico. For many people, infection with this mosquito-borne virus causes an illness with symptoms just like those experienced by Watkins: fever, skin rash, joint pain and conjunctivitis. For others, these symptoms are so mild that they go completely unnoticed.

Related: Zika virus spreads across Americas - in pictures

Related: Zika forest: birthplace of virus that has spread fear across the world

Continue reading...




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[ Cooking & Recipes ] Open Question : My mom keeps putting me down and making fun of the meals I was making before using hello fresh and it hurts my feelings ?




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[ Other - Games & Recreation ] Open Question : A dnd session where the party killed a manticore and decided to bring the corpse back to town to sell. How much money should this give them?




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[ Elections ] Open Question : See why Boris Johnson will tell public to ‘stay alert, control the virus and save lives’ ?

https://diazhub.com/news/boris-johnson-will-tell-public-to-stay-alert-control-the-virus-and-save-lives/




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[ Politics ] Open Question : Would Northern Ireland be different to the Republic of Ireland culturally?




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[ United States ] Open Question : How do I report my income to irs. What forms should I be using?

I am a dog sitter for my sister, she pays me around $100 a week. I also do extra chores around the house such as cleaning as an exchange for not paying rent. The money she pays me is usually transferred through zelle or paid cash. Im not sure if I would be considered an independent contractor or an employee. Also does she have to report to the irs my income and what forms would she have to use? Ive always received w2s from employers, so I’m Clueless to what I should do this tax season.  Thank you in advance!  Sorry I forgot to mention that my income for this last year was approximately $5000




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[ Polls & Surveys ] Open Question : What happens if you go to a concert just to stand in the corner and stink the place up with your farts?




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[ Politics ] Open Question : Why can democrats never explain how sexism against women is a real issue when they get special treatment in society and courts?

Feminism is a lie and useless in modern America, patriarchy is a good thing and natural order of society. Women be like I'm oppressed cause I don't always get my way and choose careers that pay less