Component makers are also working overtime to restart factories, but delays in getting approvals are causing hindrance in some states, especially in Maharashtra and Tamil Nadu that have the biggest automotive manufacturing hubs, industry insiders said. This, they said, could weigh on the plans of the automakers.

“We have got clearance to open the office from the local authorities and are following the guidelines given by the government,” said a spokesperson for Maruti Suzuki India Ltd, the country’s biggest car maker. The company’s Delhi corporate office is at Nelson Mandela Marg.

Mukesh Ambani just sealed three deals in as many weeks to raise a combined $8 billion. And he isn't done yet.

Milwaukee Journal Sentinel: ‘We have to test more people’: Wisconsin expands coronavirus testing for African American, Latino and tribal communities. “All African Americans, Latinos and tribal community members in Wisconsin will have access to free COVID-19 testing under a plan announced Thursday by Gov. Tony Evers. Evers’ plan is an effort to combat the staggering … Continue reading ‘We have to test more people’: Wisconsin expands coronavirus testing for African American, Latino and tribal communities (Milwaukee Journal Sentinel)

Banksy droped off an art piece that is inspiring the world with its superhero nurse theme, in gratitude to NHS Southampton General Hospital in England.

The post Banksy Drops Off Superhero Nurse Artwork at Hospital in UK With a Thank You Note appeared first on Good News Network.

The British government has told airlines it will introduce a 14-day quarantine period for most people arriving from abroad to try to avoid a second peak of the coronavirus pandemic, an association representing the airlines said on Saturday.

The four parts of the UK could now move at ‘different speeds’ in adapting their Coronavirus restrictions

MIKE ELLIOTT, the former MILWAUKEE host, PD, GM, and sportscaster and HOUSTON ASTROS broadcaster, died APRIL 20th of pneumonia in BAYSIDE, WI at 82. ELLIOTT started his career at … more

Momofuku is a group of restaurants owned by renowned chef and founder, David Chang.

Unicef is the world’s leading organisation working for children in danger. Make a donation, fundraise or campaign – help us keep children safe.

Lakukan Ini, Dapatkan Panduan Itu Di Situs Poker Online Situs Poker Online – Jika Anda ingin mencari tahu di mana harus bermain game poker internet, lakukan pencarian online untuk kamar poker internet dan lihat sejumlah situs terkait poker online yang memiliki ulasan dan peringkat situs poker terperinci di halaman mereka. Akhirnya sebelum Anda mulai bermain […]

The post Lakukan Ini, Dapatkan Panduan Itu Di Situs Poker Online appeared first on Themegalaxy.

Scenic Road Trips in the UK that are Worth Capturing by Camera Some people like hiking. Some people like cycling. But, after chatting with online car dealership Carspring, it seems you can have just as much fun exploring your next trip in the complete, climate-controlled comfort of your car. Here we go through the most unforgettable road trips in England, Scotland and Wales. Drives that offer driving heaven, stunning scenery and plenty of fun along the way. All you need is the right company and you are all set to enjoy! England: Road from Glastonbury to Cheddar Gorge – Check out the route here. This route gives you a proper feel of medieval England. Begin deep in England’s spiritual realm on the outskirts of the hallowed town on Glastonbury (Therefore avoid at a certain summer weekend). Start at the Tor on the edge of town, where hippies will tell you ... Read more

The post Unforgettable Road Trips in the UK-A new of enjoying your next travel appeared first on Digital Photography Tutorials.

We have a very special guest, Jinjer vocalist Tatiana Shmayluk called into the show. She talked about the band's upcoming...

The post METAL INJECTION LIVECAST #537 - Hootie and the No Fish with JINJER's Tatiana Shmayluk appeared first on Metal Injection.

The present invention relates to oligomer compounds (oligomers) for the treatment and prevention of acute myeloid leukemia, which target GLI2 mRNA in a cell, leading to reduced expression of GLI2.

A digital jukebox (14) allows for playback of a first offering and a second offering. The contents of each offering are individually licensed for public performance at a particular location where the jukebox is found. The jukebox (14) displays advertisements that are selected in response to user interaction with the jukebox or a number of other factors. The jukebox (14) features a screen (18 and 20) that allows user to interact with the jukebox to select offerings, but also to respond to advertising. Jukebox can function in cooperation with a server (12), but in the alternate, can function as an independent and stand-alone device when connection (16) to server (12) is not available.

Compositions and methods for improved delivery of macromolecules into eukaryotic cells are provided. Fusogenic peptides from fusion proteins of non-enveloped viruses enhance the efficiency of transfection of eukaryotic cells mediated by transfection agents such as cationic lipids, polycationic polymers such as PEI and dendrimers. These fusogenic peptides are used as part of a transfection complex that efficiently delivers a macromolecule, for example, a nucleic acid, into a eukaryotic cell. Novel cationic lipids and compositions of cationic lipids also are provided that may be used for the introduction of macromolecules such as nucleic acids, proteins and peptides into a variety of cells and tissues. The lipids can be used alone, in combination with other lipids and/or in combination with fusogenic peptides to prepare transfection complexes.

The invention relates to a human Interleukin-2 (hIL-2) specific monoclonal antibody (mAb), or antigen binding fragment thereof, the binding of which to hIL-2 inhibits binding of hIL-2 to CD25 and the antibody is characterized by any of the parameters: the variable chain of the mAb comprises the amino acid sequence of SEQ ID NO 005 or SEQ ID NO 006; the binding to hIL-2 is characterized by a dissociation constant (KD)≦7.5 nmol/L; the binding to hIL-2 is characterized by an off-rate (Koff)≦1×10−4 s−1 and/or the antibody displays no measurable cross-reactivity to murine IL-2.

The invention provides compositions and methods for treating leukemia, for example, acute myeloid leukemia (AML) and B-cell acute lymphoid leukemia (B-ALL). The invention also relates to at least one chimeric antigen receptor (CAR) specific to CD123, vectors comprising the same, and recombinant T cells comprising the CD123 CAR. The invention also includes methods of administering a genetically modified T cell expressing a CAR that comprises a CD123 binding domain. The invention also includes methods of bone marrow ablation for use in treatments necessitating bone marrow reconditioning or transplant.

The present invention provides methods for assessing whether a subject is at risk of developing a neurological disorder, diagnosing or confirming whether a subject is afflicted with a neurological disorder, assessing whether PD has progressed in a subject afflicted with PD, assessing whether a neurological disorder is developing in a subject who has been identified as being at risk of developing the neurological disorder, assessing whether a subject afflicted with a neurological disorder is likely to benefit from a therapy, assessing whether a subject afflicted with a neurological disorder has benefited from a therapy, treating a subject afflicted with a neurological disorder, and prophylactically treating a subject who has been identified as being at risk of developing a neurological disorder. The present invention also provides epitopes, compounds and compositions relating to these methods.

The present invention relates to an in vitro method of diagnosing chronic myelomonocytic leukemia (CMML) in a subject, said method comprising the steps of: a) Detecting a monocyte population in a biological sample from said subject; b) Quantifying the CD14+/CD16− monocytes in said biological sample; c) Comparing the value of step b) to a reference value; and d) Diagnosing CMML based on said comparison. Preferably, said detecting step a) is performed by an exclusion gating strategy by flow cytometry.

Despite a surge in support for independence in the last few weeks, the Better Together campaign came through with a majority sufficient to put to bed the question of independence for Scotland, at least for now.

A SOUTHAMPTON grandmother spent years battling cancer.

THE Olivier Award-nominated production of Singin’ in the Rain will embark on a major UK and Ireland tour in 2021, making a splash in Southampton next spring.

FRANK Turner's Hampshire homecoming gig this week has been cancelled due to the threat of Coronavirus.

So now it’s officially confirmed by the man himself! After various celebrity sightings in the New Forest, Mayflower Park and Overdraft Craft Ale Bar Shirley, soul man of the moment Michael Kiwanuka dedicated a heartfelt rendition of Home Again to a sold out audience at the O2 Guildhall last night.

A “TOOTHLESS” attempt to curb the number of people taking part in mass cycling events in the New Forest looks set to be ignored.

THE Duke of Edinburgh has taken to the waters to watch Sir Ben Ainslie prepare in his bid to bring back the America's Cup to Britain for the first time in 165 years.

A TURKISH restaurant in Southampton, which launched in a blaze of glory last year winning Best Middle Eastern Restaurant in the UK, is crowd funding to reopen following the coronavirus crisis.

It's quite possibly the most adventurous ukulele player ever, in this encore session from Jake Shimabukuro. Join us as we revisit this interview/performance with WNCW morning host Martin Anderson. Mahalo, Jake!

Momentum building around one of Europe’s largest regeneration schemes in Solihull.

Stephen Pennell gives the lowdown on another night in Digbeth.

Anton Pukshansky’s name may be unfamiliar to hip-hop fans, but you definitely know his work. He was a key person at Power Play Studios in Queens, New York, and was deeply involved as an engineer, musician, and producer on classic performances by Kool G. Rap and Polo, Main Source, Eric B. and Rakim, Organized Konfusion, Akinyele, and more.

He also got a front-row seat to the development of soon-to-be iconic talents like Nas and Mobb Deep, who he worked with at the very beginning of their careers. Anton worked hand-in-hand with one of hip-hop’s greatest producers, Large Professor, and has also won Grammys for his work with Santana and Ozomatli.

See http://theciphershow.com/episode/147/ for full show notes and comments.

Birmingham-based Cure Leukaemia has announced record financial results that will see the charity double the amount of funding for research nurses in the West Midlands.

Fire fighters from Highgate, Kings Norton, Ladywood and Northfield fire stations are taking on a job like no other

Crescent Theatre to host glamorous international event.

Event aims to celebrate diversity in response to anti-LGBTQ protests.

 Moseley has been crowned as the best place in Britain for city living, according to the Sunday Times.

Fundraisers share their own poignant memories.

Fund raising by fire security company helps charities.

The Naukri JobSpeak is a monthly Index which calculates and records hiring activity based on the job listings on Naukri.com website month on month. The objective is to measure the hiring activities in various industries, cities, functional areas and experience levels.

The company said it would announce the locations of the restaurants next week, with plans to open them on May 13.

The first-half loss reflected an 11.1 percent slump in underlying sales in Mothercare's home market, which it blamed on wider market uncertainty and "negative press coverage" of its financial restructuring.

With 167 stores across 18 countries, Hamleys gives Reliance Retail a much-needed global footprint.

Even with Reliance's considerable experience, turning a trophy into a titan isn’t a given.

The 49-year-old, who has been lodged at Wandsworth Prison in south-west London since his arrest last year, appeared before a UK court via videolink.

Bansal said the startup has so far raised around $160 million and only less than 20% of the funds were utilised so far and the balance funds will be spent over the next few years towards developing fitness devices and technology platform, apart from expanding the footprint.

Hero Cycles picked up majority stake in UK-based Avocet Sports to mark entry into high-end bicycle market in Europe for an undisclosed sum.

I’M very worried about what’s going to happen after the weekend when the rest of the UK begins to ease lockdown, while Scotland chooses not to.